• Journal of Chest Surgery
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• v.34 no.6
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• pp.441-446
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• 2001

Background: Electrical breathing pacing has many advantages over mechanical ventilation. However, clinically permanent diaphragmatic pacing has been applied to limited patients and few temporary pacing has been reported. Our purpose is to investigate the feasibility of temporary electrical diaphragm pacing in explothoracotomy canine cases. Methods: Five dogs were studied under the general anesthesia. Left 5th intercostal space was opened. Self designed temporary pacing leads were placed around the left phrenic nerve and connected to the myostimulator. Chest wall was closed after tube insertion with underwater drainage. Millar catheter was introduced to the aorta and right atrium. Swan-Ganz catheter was introduced to the pulmonary artery. When the self respiration was shallow with deep anesthesia, hemodynamic and tidal volume were measured with the stimulator on. Results: Tidal volume increased from 143.3$\pm$51.3 ml to 272.3$\pm$87.4 ml(p=0.004). Right atrial diastolic pressure decreased from 0.7$\pm$4.0 mmHg to -10.5$\pm$4.7 mmHg(p=0.005). Pulmonary arterial diastolic pressure decreased from 6.1+2.5 mmHg to 1.2$\pm$4.8 mmHg(p<0.001). The height of water level in chest tube to show intrathoracic pressure change was from 10.3$\pm$6.7cmH$_{2}$O to 20.0$\pm$5.3 cmH$_{2}$O. Conclusion: Temporary electrical diaphragmatic pacing is a simple method to assist respiration in explothoracotomy canine cases. Self designed pacing lead is implantable and removable. Negative pressure ventilation has favorable effects on the circulatory system. Therefore, clinical application of temporary breathing pacing is feasible in thoracotomy patients to assist cardiorespiratory function.

• Investigative Magnetic Resonance Imaging
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• v.18 no.1
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• pp.7-16
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• 2014

Purpose : To evaluate the prevalence and pattern of perfusion defect (PD) on first-pass stress perfusion MR imaging in relation with the degree of left ventricular hypertrophy (LVH) and late gadolinium-enhancement (LGE) in patients with apical hypertrophic cardiomyopathy (APH). Materials and Methods: Cardiac MR imaging with first-pass stress perfusion, cine, and LGE sequence was performed in 26 patients with APH from January 2008 to December 2012. We analyzed a total of 416 segments for LV wall thickness on end-diastolic phase of cine images, and evaluated the number of hypertrophied segment and number of consecutive hypertrophied segment (NCH). We assessed the presence or absence of PD and LGE from all patients. If there was PD, we subdivided the pattern into sporadic (sporadic-PD) or ring (ring-PD). Using univariate logistic method, we obtained the independent predictor for presence of overall PD and ring-PD. Results: PD on stress perfusion MRI was observed in 20 patients (76.9%), 12 of them (60%) showed ring-PD. Maximal LV wall thickness and number of hypertrophied segment were independent predictors for overall PD (all, p < 0.05). NCH with more than 3 segments was an additional independent factor for ring-PD. However, LGE was not statistically related with PD in patients with APH. Conclusion: About three quarters of the patients with APH showed PD, most of them represented as ring-PD. LVH degree or distribution was related with pattern of PD, however, LGE was not related with PD. Therefore, the clinical significance of PD in the patients with APH seems to be different from those with non-APH, and further comparison study between the two groups should be carried out.

• Journal of the Korean Society of Food Science and Nutrition
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• v.33 no.2
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• pp.349-355
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• 2004

The purpose of this study was to estimate effect of academic examination stress on taste perception and nutrient intakes in university students. Physical status, blood pressure, stress score using stress test of 2 types, recognition threshold and preference for taste, nutrient intakes using diet record method were measured before and after examination in 20 subjects. Mean age, height, weight, and BMI of the subjects were 23.39$\pm$1.20 years, 164.56$\pm$7.99 cm, 60.66$\pm$13.23 kg, 22.28$\pm$4.56 kg/$m^2$, respectively. Stress scores before examination of the subjects were significantly higher than those after examination. There were no significant differences in blood pressure, pulse rate, recognition threshold and just right concentration for sweetness and saltness, and food and nutrient intakes between pre- and post-examination. There were significantly positive correlation between stress score and diastolic blood pressure. And threshold concentration for saltness was positively correlated with threshold concentration for sweetness and animal protein intake. These results show no effect of examination stress on taste perception and nutrient intakes in university students. This may be due to low level of stress. Therefore, it is needed to study about effect of more higher level of stress on taste perception and nutrient intakes.

• Journal of the Korean Society of Radiology
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• v.9 no.4
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• pp.213-217
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• 2015

To report problems found in a patient who has implemented stent implantation and then conducted a perfusion MRI using ASL(Arterial Spin Labeling), in order to suggest a solution to them. The perfusion MRI was conducted, using pCASL among ASL methods. Data from pCASL(Pseudo Continuous Arterial Spin Labeling) was acquired together with the structural image simply by changing position(labeling gap 15 mm, 170 mm) of the labeling pulse to avoid stent. Data was processed through the ASLtbx. When perfusion MRI was acquired using pCASL, it showed that the position of the conventional labeling pulse (labeling gap 24 mm) was overlapped with that of stent, which made signal intensity in right brain tissue appear as if it were void. When the labeling pulse was positioned (labeling gap 15 mm) to avoid stent, high signal intensity images were acquired. In labeling pulse (labeling gap 170 mm), the signal intensity was more reduced due to relaxation before labeled blood arrived at the imaging slice. pCASL can be stably repeated measurements because it does not use a contrast agent. And it should be selected with the appropriate image acquisition parameters for the high quality image.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.8
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• pp.3696-3703
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• 2013

This study is a qualitative case study for discovering any change in the perception of elderly women about sexuality through a group counseling program. For this the study selected eight elderly people who are female aged 65 or over living in D city and have a spouse who is able to have a consistent sex life. Then the study collected relevant data by offering eight sessions of a group counseling program, and carried out an analysis with an approach to case studies. As a result of the research, there were changes in their perceptions about and current life satisfaction, relationships for unity, pleasure relaxation active self-expression, sexual relations. After their participation in the program, participants had a positive perception about a sex concept, namely sexuality and they came to think about the need for an increase of sexuality for raising the satisfaction of life in late years. These research results would be offered as basic data of research into sexuality which may be able to enhance the quality of the lives of elderly people, such as the positive recognition of sex, active sexual intercourses, and the improvement of self-esteem.

• Journal of Korea Game Society
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• v.15 no.2
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• pp.63-72
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• 2015

Avatars are a visual representation of users in a virtual world such as an MMORPG. These avatars are often seen as representations or idealizations of the user's actual self. However, this view does not account for the prevalence of two behaviors: multiple avatars and 'gender swapping'. An exercise and questionnaire were created to study avatar customization practices across players outside the context of any particular game to understand better user motivations in creating their virtual selves. A preliminary trial of the exercise showed little correlation between age or gender and gender swapping. While those of non-traditional sexuality were more likely to gender swap, half of traditional sexuality also swapped. Finally, the personality trait, Openness to Experience, showed promising correlation with gender swapping.

• Progress in Medical Physics
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• v.12 no.1
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• pp.31-39
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• 2001

NMR spectroscopy enables us to measure the molar concentration of the metabolites in the organisms, and this technique is the only method to measure the concentration non-invasively. The proton NMR spectroscopy has been used to study the biochemical changes in human as well as in animal brain. MRI uses the proton densities and its relaxation times for reconstructing images, but MRS gives the biochemical changes inside the body. NMR spectroscopy could provide the information which MRI and CT could not, and this makes NMR spectroscopy more useful in diagnosing diseases. This study was tried to develop the quantitation of the molar concentration of the metabolites in the brain using the proton MR spectroscopy. The spectra of each metabolites was obtained, and the proton MR spectra was obtained from the insula gray matter areas of the 16 volunteers. And this spectra was analyzed to estimated the molar concentrations of the metabolites in the region. The results showed the very similar to those of the others.

• Physical Therapy Korea
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• v.14 no.1
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• pp.55-63
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• 2007

This study was designed to examine the relationship between clinical symptoms, self-efficacy, and performance of women with osteoarthritis. It is a survey study of 60 women who were diagnosed as osteoarthritis and given medical treatments from September, 2005 to October, 2005 in hospital 'H' located in Yongin-si. For clinical symptoms, radiographs of the subjects' knees were taken and evaluated the pathology grade by the Kellgren-Lawrence grade. Pain and stiffness was measured by the measure of WOMAC (Western Ontario and McMaster Universities Osteoarthritis Index), and functional reach test was measured in order to examine balancing abilities. Self-efficacy was measured by a tool which has revised the ASES (Arthritis Self-Efficacy Scale), and performance was measured by recording the difficulty of the WOMAC measurements themselves, and the time taken for 20 m walking, going up and down 9 stairs, and 5 sit-down and stand-up repetitions. The resulting differences in the other variables according to performance and the relationship between performance with variables are the following. First, an increase in pain in women with osteoarthritis led to decreased functional ability. Second, an increase in stiffness in women with osteoarthritis led to a decrease in functional ability. Third, a decrease in balance in women with osteoarthritis led to a decrease in functional ability. Fourth, a decrease in self-efficacy in women with osteoarthritis led to a decrease in functional ability. Fifth, the variables for estimating the performance by self-report were pain and self-efficacy. The variables for estimating the performance by recording the time taken was balance and self-efficacy. As a result factors such as pain, balance and self-efficacy in women with osteoarthritis were closely related to performance. Based on the results, it seems that physical therapy programs to decrease pain and to increase the balance in women with osteoarthritis, and psychological approaches to increasing self-efficacy are needed. I hope that the results of this study will be useful data for clinical management and intervention for women with osteoarthritis.

• The Journal of Korean Academic Society of Nursing Education
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• v.13 no.1
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• pp.95-104
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• 2007

연구목적: 고혈압환자의 효과적인 자가관리 간호중재를 개발하는데 필요한 기초자료로 혈압자가측정(self-monitoring of blood pressure)에 대한 특성, 장점, 범위 및 제한점을 파악한다. 연구방법: 1996년부터 2005년까지 PubMed에 수록된 고혈압환자의 자가관리 방법중 혈압자가측정방법이 포함된 외국의 연구를 중심으로 체계적인 고찰을 실시하였다. 전체 69개 자가관리방법을 적용한 논문 중에서 혈압자가측정이나 가정에서의 혈압측정(home monitoring)에 대한 45개 논문을 선정하여 분석하였다. 연구결과 전반적으로 혈압자가측정 방법은 고혈압환자의 혈압조절을 향상시키는 효과가 유의한 것으로 나타났다. 환자가 혈압을 자가측정한 방법에서 평균 혈압, 수축기 혈압, 맥압이 유의하게 감소한 것으로 보고되었다. 장기적 프로그램에서 혈압조절율이 향상되거나, 이완기혈압의 감소효과도 보고되었다. 혈압자가측정의 기준치는 연구마다 일치하지는 않았지만 135/85mmHg 수준이 정상혈압의 상한수준으로 제시되었다. 일부 연구에서는 가정 내 혈압측정이 24시간혈압측정을 대체하는 방법으로 추천되었다. 보다 정확한 혈압자가측정을 위해서 신뢰성 있는 혈압측정기구의 사용과 정확한 측정방법이 환자들에게 교육될 필요가 있다. 결론: 혈압자가측정은 고혈압환자의 혈압조절에 유용한 방법으로 고찰되었다. 또한 고혈압의 진단, 혈압치료와 고혈압 약물복용 행위를 향상시키는 교육적 효과도 긍정적으로 나타났다. 따라서 고혈압환자를 위한 효과적인 자기조절프로그램에 혈압자가측정법을 포함하는 것이 추천되며, 추후 한국에서 시도된 관련 연구에 관한 문헌고찰의 비교연구가 필요하다.

• Investigative Magnetic Resonance Imaging
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• v.5 no.1
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• pp.33-37
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• 2001

Purpose : The water exchange rate between bulk water and bound water is an important parameter in deciding the efficiency of paramagnetic contrast agents. In this study, we evaluated the water exchange rates of various Gd-chelates using oxygen-17 NMR technique. Material and Methods : The samples (Gd-DTPA, Gd-DTPA-BMA, Gd-DOTA, Gd-EOB-DTPA) were prepared by mixing 5% $^{17}O-enriched$ water (Isotech, USA). The pH of the samples was adjusted to physiological value [pH=7.0] by buffer solution. The variable temperature $^{17}O-NMR$ measurements were performed using Bruker-600 (14.1 T, 81.3 MHz) spectrometer. Bruker VT-1000 temperature control units were used to stabilize the temperature. The $^{17}O$ spin-spin relaxation times (T2) were measured using Carr-Purcell-Meiboom-Gill (CPMG)I pulse sequence with 24 echo trains. The variable temperature T2 relaxation data were then fitted into Solomon-Bloembergen equations using least square fit algorithm to estimate the water exchange times. Results : From the measured $^{17}O-NMR$ relaxation rates, the determined water exchange rates at 300K are $0.42{\;}{\mu}s$ for Gd-DTPA, $1.99{\;}{\mu}s$ for Gd-DTPA-BMA, $0.27{\;}{\mu}s$ for Gd-DOTA, and $0.11{\;}{\mu}s$ for Gd-EOB-DTPA. The Gd-DTPA-BMA showed slowest exchange whereas Gd-EOB-DTPA had fastest water exchange rate. In addition, it was found that the water exchange rates (${\tau}_m$) of all samples had exponential temperature dependence with different decay constant. Conclusion : $^{17}O-NMR$ relaxation rate measurements, when combined with variable temperature technique, provide a solid tool for studying water exchange rate, which is very important in investigating the detailed mechanism of relaxation enhancement effect of the paramagnetic contrast agents.