• Tuberculosis and Respiratory Diseases
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• 제61권6호
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• pp.533-546
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• 2006

Background: The aim of this study was to determine the effectiveness of self-efficacy promoting pulmonary rehabilitation in patients with chronic obstructive pulmonary disease (COPD). Methods: thirty six patients, with clinically stable COPD were randomly assigned: 18 to a rehabilitation group and another 18 as a control group, The subjects participated in a the self-efficacy promoting pulmonary rehabilitation program for 8 weeks. This program consisted of education, breathing retraining, exercise training, relaxation and counseling. The control group received education only. The outcome variables were self-efficacy, dyspnea, exercise endurance, pulmonary function, and quality of life. Dyspnea was measured using the modified Borg scale. Exercise endurance was measured by the six minute walking distance. The quality of life was measured by the quality of life index for pulmonary disease patients. Results: In the rehabilitation group after performing the self-efficacy promoting pulmonary rehabilitation program, the self-efficacy score, exercise endurance, and quality of life score were higher than the control group (p=0.007, p=0.038, and p=0.039, respectively). and the exertional dyspnea score was significantly lower than controls(p=0.045). However, the dyspnea score and FEV1 were similar after performing the self-efficacy promoting pulmonary rehabilitation program. Conclusion: The self-efficacy promoting pulmonary rehabilitation program is effective to in improve self-efficacy, exertional dyspnea, exercise endurance and quality of life in patients with COPD.

• Progress in Medical Physics
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• 제25권2호
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• pp.72-78
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• 2014

The aim of the study is to test a hypothesis that quasi-breath-hold (QBH) biofeedback improves the residual respiratory motion management in gated 3D thoracic MR imaging, reducing respiratory motion artifacts with insignificant acquisition time alteration. To test the hypothesis five healthy human subjects underwent two gated MR imaging studies based on a T2 weighted SPACE MR pulse sequence using a respiratory navigator of a 3T Siemens MRI: one under free breathing and the other under QBH biofeedback breathing. The QBH biofeedback system utilized the external marker position on the abdomen obtained with an RPM system (Real-time Position Management, Varian) to audio-visually guide a human subject for 2s breath-hold at 90% exhalation position in each respiratory cycle. The improvement in the upper liver breath-hold motion reproducibility within the gating window using the QBH biofeedback system has been assessed for a group of volunteers. We assessed the residual respiratory motion management within the gating window and respiratory motion artifacts in 3D thoracic MRI both with/without QBH biofeedback. In addition, the RMSE (root mean square error) of abdominal displacement has been investigated. The QBH biofeedback reduced the residual upper liver motion within the gating window during MR acquisitions (~6 minutes) compared to that for free breathing, resulting in the reduction of respiratory motion artifacts in lung and liver of gated 3D thoracic MR images. The abdominal motion reduction in the gated window was consistent with the residual motion reduction of the diaphragm with QBH biofeedback. Consequently, average RMSE (root mean square error) of abdominal displacement obtained from the RPM has been also reduced from 2.0 mm of free breathing to 0.7 mm of QBH biofeedback breathing over the entire cycle (67% reduction, p-value=0.02) and from 1.7 mm of free breathing to 0.7 mm of QBH biofeedback breathing in the gated window (58% reduction, p-value=0.14). The average baseline drift obtained using a linear fit was reduced from 5.5 mm/min with free breathing to 0.6 mm/min (89% reduction, p-value=0.017) with QBH biofeedback. The study demonstrated that the QBH biofeedback improved the upper liver breath-hold motion reproducibility during the gated 3D thoracic MR imaging. This system can provide clinically applicable motion management of the internal anatomy for gated medical imaging as well as gated radiotherapy.

• Progress in Medical Physics
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• 제24권3호
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• pp.135-139
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• 2013

We evaluated the effect of two kinds of breathing biofeedback technique such as audio-instruction and audio-visual biofeedback on breathing reproducibility and the CTV coverage during repeated treatment regimes in respiration-gated radiotherapy. In this study, the breathing data of nineteen lung cancer patients acquired from Medical College of Virginia (MCV) during five weeks were used. The dose evaluation algorithm was programmed in MATLAB. In the result, the CTV coverage was decreased as 30.0% due to the breathing irreproducibility for free-breathing. For audio-visual biofeedback, the CTV coverage was improved as 20.0% because patients can learn how control their breathing stably. And the audio-instruction was effective to preserve the breathing reproducibility.

• Investigative Magnetic Resonance Imaging
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• 제18권3호
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• pp.244-252
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• 2014

Purpose : We proposed a multi-physiological signals based real-time intelligent triggering system(MITS) for Cardiac MRI. Induced noise of the system was analyzed. Materials and Methods: MITS makes cardiac MR imaging sequence synchronize to the cardiac motion using ECG, respiratory signal and second order derivative of $SPO_2$signal. Abnormal peaks due to arrhythmia or subject's motion are rejected using the average R-R intervals and R-peak values. Induced eddy currents by gradients switching in cardiac MR imaging are analyzed. The induced eddy currents were removed by hardware and software filters. Results: Cardiac MR images that synchronized to the cardiac and respiratory motion are acquired using MITS successfully without artifacts caused by induced eddy currents of gradient switching or subject's motion or arrhythmia. We showed that the second order derivative of the $SPO_2$ signal can be used as a complement to the ECG signals. Conclusion: The proposed system performs cardiac and respiratory gating with multi-physiological signals in real time. During the cardiac gating, induced noise caused by eddy currents is removed. False triggers due to subject's motion or arrhythmia are rejected. The cardiac MR imaging with free breathing is obtained using MITS.

• Journal of the Korea Institute of Information and Communication Engineering
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• 제24권9호
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• pp.1138-1143
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• 2020

MRI scans in the abdominal area are difficult to achieve optimal images due to artificial respiration. Among 45 patients (male:female = 30:15) who underwent abdominal MRI examination, a metronome-based examination method was studied for patients whose breathing is difficult and difficult to examine. The images examined without using a metronome were divided into group A, and the images examined using a metronome were divided into group B. Image quality improvement (30%) and inspection time (approximately 50 seconds) were reduced in images using metronome. During abdominal magnetic resonance imaging (ABD MRI), the images examined using a metronome had differences in quality and examination time compared to the unused images. It is more effective to use a metronome brace that controls the patient's respiratory rate during abdominal magnetic resonance imaging under respiratory induction in patients with difficulty in respiratory-gated.

• Investigative Magnetic Resonance Imaging
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• 제15권1호
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• pp.22-31
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• 2011

Purpose : To compare free-breathing and respiratory-triggered diffusion-weighted imaging on 1.5-T MR system in the detection of hepatic lesions. Materials and Methods: This single-institution study was approved by our institutional review board. Forty-seven patients (mean 57.9 year; M:F = 25:22) underwent hepatic MR imaging on 1.5-T MR system using both free-breathing and respiratory-triggered diffusion-weighted imaging (DWI) at a single examination. Two radiologists retrospectively reviewed respiratory-triggered and free-breathing sets (B50, B400, B800 diffusion weighted images and ADC map) in random order with a time interval of 2 weeks. Liver SNR and lesion-to-liver CNR of DWI were calculated measuring ROI. Results : Total of 62 lesions (53 benign, 9 malignant) that included 32 cysts, 13 hemangiomas, 7 hepatocellular carcinomas (HCCs), 5 eosinophilic infiltration, 2 metastases, 1 eosinophilic abscess, focal nodular hyperplasia, and pseudolipoma of Glisson's capsule were reviewed by two reviewers. Though not reaching statistical significance, the overall lesion sensitivities were increased in respiratory-triggered DWI [reviewer1: reviewer2, 47/62(75.81%):45/62(72.58%)] than free-breathing DWI [44/62(70.97%):41/62(66.13%)]. Especially for smaller than 1 cm hepatic lesions, sensitivity of respiratory-triggered DWI [24/30(80%):21/30(70%)] was superior to free-breathing DWI [17/30(56.7%):15/30(50%)]. The diagnostic accuracy measuring the area under the ROC curve (Az value) of free-breathing and respiratory-triggered DWI was not statistically different. Liver SNR and lesion-to-liver CNR of respiratory-triggered DWI ($87.6{\pm}41.4$, $41.2{\pm}62.5$) were higher than free-breathing DWI ($38.8:{\pm}13.6$, $24.8{\pm}36.8$) (p value < 0.001, respectively). Conclusion: Respiratory-triggered diffusion-weighted MR imaging seemed to be better than free-breathing diffusion-weighted MR imaging on 1.5-T MR system for the detection of smaller than 1 cm lesions by providing high SNR and CNR.

• Journal of radiological science and technology
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• 제39권2호
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• pp.149-156
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• 2016

Measurement of cardiac blood flow using the magnetic resonance imaging has been limited due to breathing and involuntary movements of the heart. The present study attempted to improve the accuracy of cardiac blood flow testing through phase contrast magnetic resonance imaging by presenting the adequate breathing method and imaging variables by comparing the measurement values of cardiac blood flow. Each was evaluated by comparing the breath hold retrospective 1NEX and non breath hold retrospective 1-3NEX in the ascending aorta and descending aorta. As a result, the average blood flow amount/velocity of the breath hold retrosepctive 1NEX method in the ascending aorta were $96.17{\pm}19.12ml/sec$, $17.04{\pm}4.12cm/sec$ respectively, which demonstrates a statistically significant difference(p<0.05) with the non-breath hold retrospective method 1NEX of $72.31{\pm}13.27ml$ and $12.32{\pm}3.85$. On the other hand, the average 2NEX blood flow and mean flow velocity is $101.90{\pm}24.09$, $16.84{\pm}4.32$, 3NEX $103.06{\pm}25.49$, $16.88{\pm}4.19$ did not show statistically significant differences(p>0.05).The average blood flow amount/ velocity of the breath hold retrospective 1NEX method in the descending aorta were $76.68{\pm}19.72ml/s$, and $22.23{\pm}4.8$, which did not demonstrate a significant difference in comparison to non-breath hold retrospective method 1-3 NEX. Therefore, the non breath hold retrospective method does not significantly differ in terms of cardiac blood flow in comparison with the breath hold retrospective method in accordance with the increase of NEX, so pediatric patients or patients who are not able to breathe well must have the diagnostic value of their cardiac blood flow tests improved.

• Proceedings of the KSMRM Conference
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• 대한자기공명의과학회 1999년도 제4차 추계학술대회 초록집
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• pp.17-18
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• 1999

최근까지 복부 자기공명영상은 간의 국소병변의 특성을 규명하는 데 가장 많이 사용되어 왔다고 할 수 있다. 그러나, 자기공명영상의 기법과 장비의 발달로 인해 그 적응증이 더욱 확대되어 가는 추세에 있고 , 특히 자기공명담췌관촬영술의 도입과 발전은 복부 자기공명영상의 적응증을 한층 넓히는 데 크게 기여하고 있다. 이와 함께, 2차원 또는 3차원 경사에코기법과 조영제를 병용하여 호흡정지 상태에서 자기공명혈관촬영상을 얻을 수 있게 되어 자기공명담췌관촬영술과 혈관촬영술을 복합하여 다양한 담췌관질환을 평가하는 데 이용하는 빈도가 증가하고 있다. 이 강의 에서는 최근에 널리 사용되는 자기공명담췌혈관촬영술 또는 역동적 역상과의 복합적 사용의 유용성을 돌아보고자 한다.

• Proceedings of the KIEE Conference
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• 대한전기학회 2011년도 제42회 하계학술대회
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• pp.2031-2032
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• 2011

일반적으로 심장자기공명영상을 이용하여 우관상동맥을 영상화 하기 위해서 3차원 데이터를 얻는다. 그렇게 하는 경우 데이터를 받는 시간이 오래 걸리고, 받은 3차원 데이터에서 차원 원하는 부분만을 2차원으로 재구성하는 작업을 해야 하는 번거러움이 있다. 반면에 호흡 정지상태에서 우관상동맥의 위치를 잘 선택하게 되면 한번 숨을 참을 수 있는 시간안에 원하는 영상을 얻을 수 있는 이점이 있다. 그렇게 하기 위해서는 우관상동맥을 찾아서 그 부분만 영상화해야 하는데, 본 논문에서는 한 영상에 같이 나타내기 어려운 대동맥에서 시작하여 심장 뒤편으로 돌아 들어가는 전체 우관상동맥을 쉽게 찾고, 한번 호흡을 참는 시간안에 영상화 하는 방법을 제안한다.

• Journal of the Korean Magnetics Society
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• 제22권5호
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• pp.178-182
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• 2012

This research suggested that the extraction of respiratory rate could be made possible by using frequency analysis in the data process for clip-type pulsimeter equipped with permanent magnet and Hall sensor. The pulse analysis included of cardiac motion information depending on variation of pulse waveforms is investigated by means of Fast Fourier Transformation (FFT). The peaks of FFT spectrums measured at 15, 20, 30, 40, and 50 tempos are coincided to each respiratory rate having 0.125 Hz, 0.16 Hz, 0.25 Hz, 0.33 Hz, and 0.41 Hz, respectively. The FFT spectrum using algorithm for the extraction of respiratory rate showed the best pulse waves measured during 300 s. Based upon these results, the clip-type pulsimeter could extract the effective respiratory rate reflecting physical effects.