• 제목/요약/키워드: 자기공명

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Hybrid Two-Dimensional Proton Spectroscopic Imaging of Pediatric Brain: Clinical Application (소아 뇌에서의 혼성 이차원 양성자자기공명분광법의 임상적 응용)

  • Sung Won Youn;Sang Kwon Lee;Yongmin Chang;No Hyuck Park;Jong Min Lee
    • Investigative Magnetic Resonance Imaging
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    • v.6 no.1
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    • pp.64-72
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    • 2002
  • Purpose : To introduce and demonstrate the advantages of the new hybrid two-dimensional (2D) proton spectroscopic imaging (SI) over the single voxel spectroscopy (SVS) and conventional 2D SI in the clinical application of spectroscopy for pediatric cerebral disease. Materials and Methods : Eighty-one hybrid 2D proton spectroscopic imaging was performed in 79 children (36 normal infants and children, 10 with hypoxic-ischemic injury, 20 with toxic-metabolic encephalopathy, seven with brain tumor, three with meningoencephalitis, one with neurofibromatosis, one with Sturge-Weber syndrome and one with lissencephaly) ranging in age from the third day of life to 15 years. In adult volunteers (n=5), all three techniques including hybrid 2D proton SI, SVS using PRESS sequence, and conventional 2D proton SI were performed. Both hybrid 2D proton SI and SVS using PRESS sequence were performed in clinical cases (n=). All measurements were performed with a 1.5-T scanner using standard head quadrature coil. The 16$\times$16 phase encoding steps were set on variable field of view (FOV) depending on the size of the brain. The hybrid volume of interest inside FOV was set as $75{\times}75{\times}15{\;}\textrm{mm}^3$ or smaller to get rid of unwanted fat signal. Point-resolved spectroscopy (TR/TE=1,500 msec/135 or 270msec) was employed with standard chemical shift selective saturation (CHESSI pulses for water suppression. The acquisition time and spectral quality of hybrid 2D proton SI were compared with those of SVS and conventional 2D proton SI. Results : The hybrid 2D proton SI was successfully conducted upon all patients.

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3.0-Tesla 자기공명 영상장치용 TX/RX C-spine RF Coil의 개발

  • 류연철;류승학;최보영;오창현
    • Proceedings of the KSMRM Conference
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    • 2001.11a
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    • pp.143-143
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    • 2001
  • 목적: 현재 3.0T MRI system은 세계적으로 개발이 진행되고 있는 가운데, 3.0T에서 사용할 수 있는 RF coil의 개발이 시급한 상황이다. 1.0T 및 1.5T MRI 와는 달리 3.0T에서 사용할 수 있는 Body coil 및 그에 따른 High power RF amplifier 제작에 많은 제약이 있다. 작은 용량의 RF amplifier를 이용하여 신체의 부분을 촬영 하고자 한다면, Tx/Rx 가능한 coil을 이용하면 가능할 것이다. 이러한 이유로 본 연구에서는 Tx/Rx 가능한 Quadrature type C-spine RF coil을 설계, 제작하여 3.0T 고자장 자기공명 영상장치에서의 임상진단 활용범위를 확대하였다.

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Study of Motion Effects in Cartesian and Spiral Parallel MRI Using Computer Simulation (컴퓨터 시뮬레이션을 이용한 직각좌표 및 나선주사 방식의 병렬 자기공명 영상에서 움직임 효과 연구)

  • Park, Sue-Kyeong;Ahn, Chang-Beom;Sim, Dong-Gyu;Park, Ho-Chong
    • Investigative Magnetic Resonance Imaging
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    • v.12 no.2
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    • pp.123-130
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    • 2008
  • Purpose : Motion effects in parallel magnetic resonance imaging (MRI) are investigated. Parallel MRI is known to be robust to motion due to its reduced acquisition time. However, if there are some involuntary motions such as heart or respiratory motions involved during the acquisition of the parallel MRI, motion artifacts would be even worse than those in conventional (non-parallel) MRI. In this paper, we defined several types of motions, and their effects in parallel MRI are investigated in comparisons with conventional MRI. Materials and Methods : In order to investigate motion effects in parallel MRI, 5 types of motions are considered. Type-1 and 2 are periodic motions with different amplitudes and periods. Type-3 and 4 are segment-based linear motions, where they are stationary during the segment. Type-5 is a uniform random motion. For the simulation, Cartesian and spiral grid based parallel and non-parallel (conventional) MRI are used. Results : Based on the motions defined, moving artifacts in the parallel and non-parallel MRI are investigated. From the simulation, non-parallel MRI shows smaller root mean square error (RMSE) values than the parallel MRI for the periodic (type-1 and 2) motions. Parallel MRI shows less motion artifacts for linear(type-3 and 4) motions where motions are reduced with shorter acquisition time. Similar motion artifacts are observed for the random motion (type-5). Conclusion : In this paper, we simulate the motion effects in parallel MRI. Parallel MRI is effective in the reduction of motion artifacts when motion is reduced by the shorter acquisition time. However, conventional MRI shows better image quality than the parallel MRI when fast periodic motions are involved.

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기능적 자기공명영상에 나타난 숫자연산의 대뇌 활성화 연구

  • 유재욱;이홍재;이동훈;문찬홍;이은정;나동규
    • Proceedings of the KSMRM Conference
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    • 2001.11a
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    • pp.103-103
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    • 2001
  • 목적: 기능적 자기공명영상을 이용하여 숫자 연산과 연관된 뇌영역을 알아보고자 하였다. 대상 및 방법: 정상 성인 자원자 6명을 대상으로 연산과제를 이용하여 연산과제와 관계된 대뇌영역 꼭 활성화를 유도하였다. 실험은 실험 I과 실험II로 나누어 진행하였다. 실험 I에서 연산과제는 스크린을 통해 보여주고 계산식이 맞는지를 판단하여 신호하도록 하였고[예:(4+5)$\times$8=72], 대조과제는 십자모양을 집중하여 보도록 하였다. 실험II에서 연산과제는 실험 I과 동일하였고, 대조과제는 화면에 제시되는 세 개의 수가 모두 홀수 또는 짝수일 때 신호하도록 하였다. 기능적 자기공명영상은 1.5T 초전도 자기공명영상장치에서 EPI BOLD 기법을 이용하여 얻었으며 6명에서 얻은 영상을 정상화(normalize)한 후 SPM 프로그램을 이용하여 통계분석을 하였다. 활성화된 뇌 영역은 모형뇌에 지도화하여 두 과제에서 활성화된 뇌 영역을 비교 분석하였다.

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