• Title/Summary/Keyword: 자가이식술

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Mosaicplasty for the Treatment of the Chondral Defect of the Knee (슬관절의 연골결손에 대한 자가 골연골 이식술)

  • Choi, Nam-Hong
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.4 no.1
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    • pp.12-17
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    • 2005
  • Several methods to resurface the lost cartilage of the knee have been used, multiple drilling, microfracture, abrasion arthroplasty Resurfaced cartilages resulting from above techniques are mostly fibrocartilage. Autologous osteochondral graft transfer and autologous chondrocyte transfer are known to resurface the lost cartilage with mostly hyaline cartilage. This article reviews basic researches, indications, operative technique, and clinical results of autologous osteochondral graft transfer.

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Mosaicplasty for The Treatment of the Chondral Defect of The Knee (슬관절의 연골결손에 대한 자가 골연골 이식술)

  • Choi, Nam-Hong
    • Journal of the Korean Arthroscopy Society
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    • v.12 no.3
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    • pp.147-153
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    • 2008
  • Several methods to resurface the lost cartilage of the knee have been used; multiple drilling, microfracture, abrasion arthroplasty. Resurfaced cartilages resulting from above techniques are mostly fibrocartilage. Autologous osteochondral graft transfer and autologous chondrocyte transfer are known to resurface the lost cartilage with mostly hyaline cartilage. This article reviews basic researches, indications, operative technique, and clinical results of autologous osteochondral graft transfer.

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Autologous Chondrocyte Implantation (자가연골 세포이식)

  • Jeong, Hwa-Jae
    • Journal of the Korean Arthroscopy Society
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    • v.12 no.3
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    • pp.159-166
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    • 2008
  • Articular cartilage is a unique tissue with no vascular, nerve, or lymphatic supply. This uniqueness may be one of the reasons why chondral injuries will hardly heal and may progress to osteoarthritis over time. Currently, there are several surgical options for the treatment of articular cartilage lesions. Although there is some discrepancy as to which procedures work best in certain patients. The spectrum of treatment alternatives for articular cartilage defects can range from simple lavage and debridement, drilling, micro-fracturing, and abrasion to osteochondral grafting and autologous chondrocyte implantation. In 1984, for the first time, results of autologous chondrocyte implantation in a rabbit model were presented, showing hyaline cartilage repair. Clinical study using autologous cultured chondrocyte implantation in chondral defects of the human knee has been reported in 23 patients in 1994. In 14 out of 16 patients treated for chondral injuries on the femoral condyles, the results were good to excellent. It is important for the surgeon to understand the autologous chondrocyte implantation technique and to be aware on the postoperative management. Attention to surgical technique and selection of appropriate patient for the autologous chondrocyte implantation will provide with the best results.

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연골 결손의 치료

  • Lee, Beom-Gu;Sim, Jae-Ang
    • 대한관절경학회:학술대회논문집
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    • 2009.10a
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    • pp.165-169
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    • 2009
  • 연골 결손은 자체 치유 능력이 적어 그 크기가 1 cm 이상인 경우 골관절염이 발생할 수 있다. 최근에는 3-tesla MRI 등의 발전으로 인해 수술 전에 미리 연골 손상을 정확히 진단할 수 있어 연골 손상의 치료를 더욱 적극적으로 할 수 있다. 이제까지 연골 손상에 대한 수술적 치료는 세척술(lavage) 및 변연 절제술(debridement), 미세 천공술(microfracture), 자가 골연골 이식술(autologous osteochondral graft), 자가 연골 세포 이식술(autologous chondrocyte implantation, ACI), 동종 골연골 이식술(osteochondral allograft)이 있다.

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Osteochondral Lesion of the Talus (거골의 골연골 병변)

  • Lee, K.B.
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.6 no.1
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    • pp.19-26
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    • 2007
  • 최근에 스포츠 손상이 증가하고 관절경을 이용한 치료가 발전하면서 조기에 더 적극적인 치료를 하는 추세이다. 또한 방사선 소견에 비하여 관절경하에서는 연골이 불안정하거나 분리되어 있는 경우도 있으므로 기존의 수술 적응증보다는 좀 더 광범위하게 관절경 검사 및 수술적 치료가 요구된다고 생각한다. 치료 방법을 하면 $1.5cm^2$ 이하의 병변을 가진 50세 이하의 환자는 관절경을 이용하여 변연 절제술, 연골하 천공, 연마, 미세 골절술, 소파술 등의 방법으로 치료할 수 있다. 같은 방법으로 50세 이상의 $3cm^2$ 이하의 병변을 가진 환자 중 mosaicplasty와 자가 연골 세포 이식술을 적용할 수 없는 환자에서 시도해볼 수 있다. $1.5\sim3cm^2$의 병변을 가진 50세 이하의 환자, 그전의 관절경적 치료로 실패한 경우에는 자가골 연골 이식 또는 자가 연골 세포 이식술을 이용하여 치료해야 한다. $3cm^2$ 이상의 병변을 가진 50세 이하의 환자는 자가 연골 세포 이식술이나 동종 골 연골 이식을 이용하여 치료하며, 50세 이상의 환자는 관절 고정술이나 족근 관절 인공치환술을 고려하는 것이 바람직하다.

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PHYSIOLOGIC ERUPTION INDUCTION OF TRANSPOSED IMPACTED UPPER INCISORS THROUGH AUTOTRANSPLANTATION (변위매복된 상악전치의 자가이식을 통한 자발적 맹출 유도)

  • Kim, Jae-Gon;Lee, Doo-Cheol;Oh, Kyong-Seon;Baik, Byeong-Ju
    • Journal of the korean academy of Pediatric Dentistry
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    • v.28 no.2
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    • pp.281-286
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    • 2001
  • The treatment method of impacted tooth is various from simple observation to surgical exposure and orthodontic methods, autotransplantation is concerned to severe malposed impacted tooth. Autotransplantation is the transplantation of embedded, impacted, of unerupted tooth, into extraction socket of surgically prepared in the same individual. Autotransplantation of tooth with $\frac{1}{2}{\sim}\frac{3}{4}$ root development provides a good chance of easily extracted, a little complication, pulp survival, and complete root formation. Transplantation of uncompleted root apex tooth is aim to pulpal healing, not endodontic treatment. The case which were treated with autotransplantation is reported, and induced normal physiologic eruption and good dental alignment.

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Surgical Treatments of Osteosarcoma around the Knee in Children (소아 슬관절 주위 골육종의 수술적 치료)

  • Nam, Kwang-Woo;Lee, Sang-Hoon;Kim, Han-Soo;Oh, Joo-Han;Cho, Whan-Sung
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.1-12
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    • 2004
  • Purpose: The current study was performed to analyze the oncological and functional results, and the patient, the limb and the prosthesis survival of osteosarcoma around the knee in children according to the treatment options. Materials and Methods: From 1982 to 2002, 63 patients with osteosarcoma around the knee underwent surgical treatments before 16 years of age. Surgical treatment options were amputation, endoprosthetic replacement, and implantation of low heat-treated autogenous bone graft after wide resection of tumor. The mean age of patients was 11.5 years (4.4~16), and the mean follow-up period was 6.1 years (2.1~16.8). All patients had neoadjuvant and adjuvant chemotherapy. All endoprosthses were extendible types. Anatomical locations of osteosarcoma were distal femur in 40 patients, and proximal tibia in 23 patients. As regard to Enneking stage, 4 patients had stage $II_A$, 50 patients had stage $II_B$, and 9 patients had stage III tumors. Results: The 5 year survival rate of stage $II_B$ patients was 72.7% in amputation, 83.7% in endoprosthesis, and 100% in low heat-treated autogenous bone graft. The 5 year survival rate of salvaged limb was 84.4% in endoprosthesis, and 80% in low heat-treated autogenous bone graft. The survival rate of prosthesis was 92.7% at 5 years, 67.4% at 10 years in endoprosthesis, and 75% at 5 years in low heat-treated autogenous bone graft. Mean functional outcome scores were 8.7 points in amputation, 20.6 points in endoprosthesis, and 16 points in low heat-treated autogenous bone graft. Distant metastasis occurred 15.8% in amputation, 27% in endoprosthesis and local recurrence occurred 8.1% in endoprosthesis, 14.3% in low heat-treated autogenous bone graft. Major complications happened 26.3% in amputation, 35.1% in endoprosthesis, and 28.6% in low heat-treated autogenous bone graft. Conclusion: Limb salvage procedure had functionally better results than amputation in children with osteosarcoma around the knee. Reconstruction with endoprosthesis after resection of tumor had good results in children as adults. In certain circumstances as too small bone for endoprosthesis or minimal bony destruction or too skeletally immature patient, low heat-treated autogenous bone graft may be a good treatment option. Low heat-treated autogenous bone graft may be considered as not only a substitute for endoprosthesis but also a temporary method before endoprosthesis.

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