• Title/Summary/Keyword: 입자 조작

Search Result 59, Processing Time 0.023 seconds

Single beam acoustic tweezers for biomedical applications (단일 빔 음향 집게를 이용한 바이오메디컬 응용 연구)

  • Hae Gyun Lim
    • The Journal of the Acoustical Society of Korea
    • /
    • v.42 no.5
    • /
    • pp.452-459
    • /
    • 2023
  • Acoustic tweezers represent an exceptionally versatile and adaptable collection of instruments that harness the intrinsic power of sound waves to manipulate a wide spectrum of bioparticles, ranging from minuscule extracellular vesicles at the nanoscale to more substantial multicellular organisms measuring in millimeters. This field of research has witnessed remarkable progress over the course of the past few decades, primarily in the domain of Single Beam Acoustic Tweezers (SBAT) which utilizes a single element transducer for its operation. Initially conceived as a method for particle trapping, SBAT has since evolved into an advanced platform capable of achieving precise translation of cells and organisms. Recent groundbreaking advancements have significantly enhanced the capabilities of SBAT, unlocking new functionalities such as particle/cell separation and controlled deformation of single cells. These advancements have propelled SBAT to the forefront of bioparticle/cell manipulation, gathering attention within the scientific community. This review explores the core principles of SBAT and how sound waves affect bioparticles/cells. We aim to build a strong conceptual foundation for understanding advancements in this field by detailing its principles and methodologies.

Research on Mobile Wheelchair Lift Design (이동식 휠체어 리프트 디자인 연구)

  • 이명기
    • Archives of design research
    • /
    • v.15 no.4
    • /
    • pp.275-284
    • /
    • 2002
  • To improve the social and economic position of the disabled people and secure their human rights, an integrated society should be buill. To build such a society, an adequate access should be provided to the movement or in using buildings or facilities. The inconveniences from social life on the part of the disabled people might not result from their impairment or disability, but from physical and social barriers in the environment surrounding them. Therefore, it is necessary to reconstruct entire systems of the society as a disabled people-friendly structure in order to remove those barriers, make them stand their own feet in our communities and freely participate in the social activities. This will eventually lead to build a society in which all people including the disabled people can use those facilities in a more convenient way. It is almost impossible for the disabled people to safely and conveniently access to and use facilities and equipments and freely move to their desired places, without any help from others in Korea. Even though, there are currently many disabled people-related convenience facilities, they have been independently built without a connection with other facilities and buildings, thus not greatly useful. Even when convenience facilities have been built, mostly they are superficially set up; therefore, in many cases, the disabled peOple cannot use those facilities. In this. research, I tried a new concept of mobile wheelchair lift design, which the disabled people can operate without restrictions, when using the public facilities. The key to this research was to develop the existing import-oriented simple functional products to a new system with functional safety and high quality orientation. Also, this research aimed at bringing an. import substitution effect, as well as preempting the mobile wheelchair lift market by advancing into overseas markets through application of new image designs in the field of disabled people aid equipments.

  • PDF

A Study on Analysis of electrolyzed water properties with pH changes (pH 변화에 따른 전리수 분석에 관한 연구)

  • Kim, Baekma;Kim, Minjung;Kim, Wohyuk;Kim, Bongsuk;Ryoo, Kunkul
    • Clean Technology
    • /
    • v.10 no.1
    • /
    • pp.47-51
    • /
    • 2004
  • 현재 반도체 공정에서 사용되는 세정기술은 대부분이 1970년대 개발된 RCA 세정법인 과산화수소를 근간으로 하는 습식 세정으로, 표면의 입자를 제거하기 위한 SC-1 세정액은 강력한 산화제인 과산화수소에 의한 표면과 입자의 산화와 암모니아에 의한 표면의 에칭이 동시에 일어나 입자를 표면으로부터 분리시킨다. 금속 불순물을 제거하기 위한 SC-2 세정액은 염산과 과산화수소 혼합액을 사용하며 금속 불순물을 용해시켜 알칼리나 금속 이온을 형성하거나 용해 가능한 화합물을 형성시켜 제거한다. 또한 황산과 과산화수소를 혼합한 Piranha 세정액은 효과적인 유기물 제거제로서 웨이퍼에 오염된 유기물을 용해 가능한 화합물로 만들거나 과산화수소에 의해 형성되는 산화막내에 오염물을 포함시켜 불산 용액으로 산화막을 제거할 때 함께 제거된다. 최근 금속과 산화막을 동시에 제거하기 위해 희석시킨 불산에 과산화수소를 첨가한 세정공정이 사용되고 있으며 불산에 의해 표면의 산화막이 제거될 때 산화막내에 포함된 금속 불순물을 동시에 제거시킬 수 있다. 그러나 이와 같이 습식세정액 내에 공통적으로 포함되어 있는 과산화수소의 분해는 그만큼 가속화되어 사용되는 화학 약품의 양이 그만큼 증가하게 되고 조작하기 어려운 단점도 있다. 이를 해결하기 위해 환경친화적인 관점으로 화학약품의 사용을 최소화하는 등 RCA세정을 보완하는 연구가 계속 진행되고 있다. 본 연구에서는 RCA세정법을 환경적으로 대체할 수 있는 세정에 사용되는 전리수의 pH변화에 따른 전리수 분석을 하였다. 전리수의 제조를 위하여 전해질로는 NH4CI (HCI:H2O:NH4OH=1:1:1)를 사용하였다. pH 11 이상, ORP -700mV~-850mV인 환원수와 pH 3 이하, ORP 1000mV~1200mV인 산화수를 제조하였으며, 초순수를 첨가하여 pH 7.2와 ORP 351.1mV상태까지 조절하였다. 이렇게 만들어진 산화수와 환원수를 시간 변화와 pH 변화에 따라 Clean Room 안에서 FT-IR과 접촉각 측정기로 실험하였다. FT-IR분석에서 산화수는 pH가 높아질수록, 환원수는 낮아질수록 흡수율이 낮아졌다. 접촉각 실험에서는 산화수의 pH가 높아질수록 환원수의 pH가 낮아질수록 접촉각이 커짐을 확인하였다. 결론적으로 전리수를 이용하여 세정을 하면, 접촉성을 조절할 수 있어 반도체 세정을 가능하게 할 수 있으며, 환경친화적인 결과를 도출할 것으로 전망된다.

  • PDF

Analysis of the Pre-service Chemistry Teachers' Cognition of the Nature of Model in the Design and Development Process of Models Using Technology: Focusing on Boyle's Law (테크놀로지를 활용한 모델의 설계와 개발 과정에서 나타난 예비화학교사의 모델의 본성에 대한 인식 분석: 보일 법칙을 중심으로)

  • Na-Jin Jeong;Seoung-Hey Paik
    • Journal of the Korean Chemical Society
    • /
    • v.67 no.5
    • /
    • pp.378-392
    • /
    • 2023
  • The purpose of this study is to analyze the pre-service chemistry teachers' cognition of the nature of model in process of designing and developing models using technology. For this purpose, 19 pre-service chemistry teachers' in the 3rd grade of a education college located in the central region observe experimental phenomena related to Boyle's law presented in the 7th grade science textbook and researchers required the design and development of a model related to the observed experimental results using technology. Based on previous studies, the nature of model were classified into two aspect: 'Representational aspect' and 'Explanatory aspect'. The 'Representational aspect' was classified into 'Representation', 'Abstraction', and 'Simplification', and the 'Explanatory aspect' was classified into 'Analysis', 'Interpretation', 'Reasoning', 'Explanation', and 'Quantification'. The pre-service chemistry teachers' cognition were analyzed by the classification. As a result of the study, the 'Representation' of the 'expressive aspect' was uniformized in the form of space that changes in volume, and the pressure was expressed as the Brightness inside the cylinder or frequency of color change of particles for 'Abstraction'. In the case of 'Simplification', the particle collision was expressed as a perfectly elastic collision, but there was a group that could not simply indicate the type of particle. In the 'Explanatory aspect', in the case of 'Analysis', volume was classified as a manipulated variable, and in the case of 'Interpretation', most groups analyzed the change in pressure through the collision of gas particles. However, the cognition involved in 'Reasoning' was not observed much. In the case of 'Explanation', there were groups that did not succeed in explanation because the area where the particles collided was not set or incorrectly set, and in the case of 'Quantification', there was a group that formulated the number of collisions per unit time, and on the contrary, there was a group that could not quantify the number of collisions because they could not be expressed in numbers.

Spray Modeling: An Augmented Reality Based Tangible 3D Modeling Interface (스프레이 모델링: 증강현실 기반의 실체적인 3차원 모델링 인터페이스 제안)

  • Jung, Hee-Kyoung;Nam, Tek-Jin
    • Archives of design research
    • /
    • v.18 no.4 s.62
    • /
    • pp.119-128
    • /
    • 2005
  • This paper presents an intuitive 3D modeling interlace based on a field study and prototype development. The process and tools of modeling were observed in workshops of professional design model making, day modeling, wood caning and glass crafting. The Spray Modeling interlace was developed from the observational analysis of the field study. It is a 3D modeling interface which combines particle spraying and day modeling in Virtual or Augmented Reality space. Virtual volume particles are sprayed on frames in Augmented Reality space as day modeling. It adopts a real air spay gun as a tangible interface device which provides coherent sound and air-force feedback. The prototype development and a user study showed that the interface supports new patterns of form development and expression. Control interfaces and requirements of auxiliary devices were found to be improved. This study examines the potential of the new interlace for designers working in 3D virtual and augmented reality. The new spraying interface is also expected to be used as an alternative interface in 3D computer workspace, games, education software and media art.

  • PDF

Study on Equilibrium, Kinetic and Thermodynamic for Adsorption of Coomassi Brilliant Blue G Using Activated Carbon (입상 활성탄에 의한 Coomassi Brilliant Blue G의 흡착에 대한 평형, 동력학 및 열역학에 관한 연구)

  • Lee, Jong-Jib
    • Clean Technology
    • /
    • v.20 no.3
    • /
    • pp.290-297
    • /
    • 2014
  • Batch adsorption studies were carried out for equilibrium, kinetics and thermodynamic parameters for adsorption of coomassi brilliant blue G (CBBG) using activated carbon with varying the operating variables like initial concentration, contact time and temperature. Equilibrium adsorption data were fitted into Langmuir, Freundlich and Dubinin-Radushkevich isotherms. From estimated separation factor of Langmuir and Freundlich, this process could be employed as effective treatment for removal of CBBG. Also from Dubinin-Radushkevich isotherm model, adsorption energy (E) indicated adsorption process is physical adsorption. From kinetic experiments, the adsorption reaction was found to confirm to the pseudo second order model with good correlation. Intraparticle diffusion was rate controlling step. Thermodynamic parameters like change of free energy, enthalpy, and entropy were also calculated to predict the nature of adsorption. The change of enthalpy (406.12 kJ/mol) indicated endothermic nature of the adsorption process. The change of entropy (1.66 kJ/mol K) showed increasing disorder in process. The change of free energy found that the spontaneity of process increased with increasing adsorption temperature.

Enrichment of Chromium(Ⅵ) by Macrorecticular DPC Resin (큰 그물 구조-DPC 수지에 의한 Cr(Ⅵ)의 농축)

  • In Hwa Woo;Tong Oh Seo;Kyu Ja Whang;Yong Keun Lee
    • Journal of the Korean Chemical Society
    • /
    • v.27 no.5
    • /
    • pp.345-352
    • /
    • 1983
  • Using a column of macrorecticular gel beads impregnated with alcohol solution of diphenylcarbarzide (DPC), the enrichment of Cr(Ⅵ) ion in 0.1M sulfuric acid was investigated. The column performance was compared with respect to the types of solid support such as Amberlite XAD and Diaion HP. Diaion HP-20 was found to be most suitable for this purpose. The break through point was increased when increasing the amount of DPC absorbed in the resin and the concentrated sample solution showed higher break through capacity than the dilute one. The extraction of Cr(Ⅵ) was not affected by the presence of 100 ppm Fe(Ⅲ) which amounted to ten times of 10 ppm Cr(Ⅵ) and the presence of other metal ions which amounted to 100 times of 10 ppm Cr(Ⅵ). Because the used gel particles were effectively regenerated with methanol, they were able to be used repeatedly.

  • PDF

Peeling Operations of Root Vegetables: Potato, Sweet Potato and Carrot (근채류(감자, 고구마, 당근)의 탈피조작)

  • Lee, Cherl-Ho;Lee, Soon-Woo
    • Korean Journal of Food Science and Technology
    • /
    • v.16 no.3
    • /
    • pp.329-335
    • /
    • 1984
  • The effect of peeling methods, spherecity and weight of potatoes and carrots on the peeling efficiency were investigated. The changes in the surface texture by peeling were estimated by Rheometer and were related to the changes in the microstructure. The optimum mechanical peeling conditions using abrasion type rotary peeler were 90 sec. at 300 rpm for potatoes, 70 sec. at 300 rpm for sweet potatoes and 60 sec. at 300 rpm for carrots. The peeling loss was influenced by the sphericity and weight of the sample. The optimum conditions for alkali peeling were 90 sec. immersion in boiling 10% NaOH solution for potatoes, 300 sec. in boiling 10% NaOH solution for sweet potatoes and 60 sec. in boiling 6% NaOH solution for carrots. Severe damage of surface structure was noticed by alkali peeling, demonstrated by denaturation of starch granules in the cell. The structural damage observed by microscope was related to the reduction of cutting force after peeling.

  • PDF

Control Effect of Hydro-kinetic Force of a Special Rudder attached Flap (플랩이 부착된 특수타의 동유체력 제어효과에 관한 연구)

  • Gim, Ok-Sok;Lee, Gyoung-Woo;Ahn, Young-Kyu
    • Journal of Navigation and Port Research
    • /
    • v.32 no.10
    • /
    • pp.771-776
    • /
    • 2008
  • The main purpose in having a control surface on a ship is to control the motion of it. It is the important element to determine the maneuvering characteristics of the ship. In this paper, the measured results has been compared with each other to predict the performance characteristics of flapped rudder's 2-dimensional section at $Re=3.0{\times}10^4$ using 2-frame grey level cross correlation PIV method. The side force of the rudder could be mainly improved by the lift force at 10 degrees angle of attack and the drag force at 20 degrees angle of attack. The separation point and boundary layer could be controlled by the change of the only flap's angle at 10 degrees angle of attack.

Development of deep learning-based holographic ultrasound generation algorithm (딥러닝 기반 초음파 홀로그램 생성 알고리즘 개발)

  • Lee, Moon Hwan;Hwang, Jae Youn
    • The Journal of the Acoustical Society of Korea
    • /
    • v.40 no.2
    • /
    • pp.169-175
    • /
    • 2021
  • Recently, an ultrasound hologram and its applications have gained attention in the ultrasound research field. However, the determination technique of transmit signal phases, which generate a hologram, has not been significantly advanced from the previous algorithms which are time-consuming iterative methods. Thus, we applied the deep learning technique, which has been previously adopted to generate an optical hologram, to generate an ultrasound hologram. We further examined the Deep learning-based Holographic Ultrasound Generation algorithm (Deep-HUG). We implement the U-Net-based algorithm and examine its generalizability by training on a dataset, which consists of randomly distributed disks, and testing on the alphabets (A-Z). Furthermore, we compare the Deep-HUG with the previous algorithm in terms of computation time, accuracy, and uniformity. It was found that the accuracy and uniformity of the Deep-HUG are somewhat lower than those of the previous algorithm whereas the computation time is 190 times faster than that of the previous algorithm, demonstrating that Deep-HUG has potential as a useful technique to rapidly generate an ultrasound hologram for various applications.