• Title/Summary/Keyword: 일산화 질소

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A Ginseng Saponin Induces Production of Nitric Oxide in Macrophages (인삼사포닌에 의한 대식세포 일산화질소 생성 유도)

  • Kim Ji Yeon;Lee Hwa Jin;Kim Ji Sun;Ahn Hanna;Ryu Jae-Ha
    • YAKHAK HOEJI
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    • v.49 no.1
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    • pp.80-85
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    • 2005
  • Ginseng root is an important remedy in oriental countries, which has been used for thousands of years. Saponins of ginseng root has been known to be the major component which mediate diverse pharmacological actions of the ginseng. Heat processing of ginseng root potentiates its biological activity such as anti-tumor and anti-oxidative activities. The butanol fraction of heat-processed ginseng (HGB) induced the production of nitric oxide in macrophages in a dose-dependent manner with IFN-${\gamma}$(30 U/ml) priming. The active component was identified as ginsenoside-$Rg_5$ from the activity-guided purification. Ginsenoside $Rg_5$ is one of major components of heat-processed ginseng and red ginseng that is responsible for the potentiated biological activities of processed ginseng. The induction of NO production by heat-processed ginseng might contribute to the potentiated biological activity of heat-processed ginseng.

Emission of Carbon Monoxide and Carbon Dioxide Gases during Fire Tests of Specimens Treated with Phosphorus-Nitrogen Additives (인-질소 첨가제로 처리된 시험편의 연소 시에 발생하는 일산화탄소와 이산화탄소 생성)

  • Chung, Yeong-Jin
    • Applied Chemistry for Engineering
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    • v.26 no.5
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    • pp.609-614
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    • 2015
  • This study was to investigate the production of combustion toxic gases of pinus rigida specimens treated with pyrophosphoric acid (PP)/4ammonuium ion ($4NH_4{^+}$), methylenepiperazinomethyl-bis-phosphonic acid (PIPEABP) and PIPEABP/$4NH_4{^+}$. Each pinus rigida plates was painted in three times with 15 wt% in the aqueous solution followed by drying the species at room temperature. Emission of combustion toxic gases was examined by the cone calorimeter (ISO 5660-1). First-time to peak mass loss rate (1st-$TMLR_{peak}$) treated with chemicals was delayed upto 66.7~250.0% compared to those of untreated specimens. For test pieces treated with the chemicals, the emission of peak carbon monoxide ($CO_{peak}$) values of 0.0136~0.0178% and peak carbon dioxide ($CO_{2\;peak}$) value of 0.04432~0.3648% were obtained, which were higher than those for the virgin plate. In particular, oxygen emission is much higher than the level of 15% which can be fatal to humans. Therefore, the resulting risk could be eliminated. However it is supposed that the combustion-toxicities were partially increased compared to those of virgin plate.

Combustion Performance Test of Syngas Gas in a Model Gas Turbine Combustor - Part 2 : NOx/CO emission Characteristics, Temperature Characteristics and Flame Structures (모델 가스터빈 연소기에서 합성가스 연소성능시험 - Part 2 : NOx/CO 배출특성, 온도특성, 화염구조)

  • Lee, Min Chul;Yoon, Jisu;Joo, Seong Pil;Yoon, Youngbin
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.41 no.8
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    • pp.639-648
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    • 2013
  • This paper describes on the NOx/CO emission characteristics, temperature characteristics and flame structures when firing coal derived synthetic gas especially for gases of Buggenum and Taean IGCC. These combustion characteristics were observed by conducting ambient-pressure elevated-temperature combustion tests in GE7EA model combustor when varying heat input and nitrogen dilution ratio. Nitrogen addition caused decrement in adiabatic flame temperature, thus resulting in the NOx reduction. At low heat input condition, nitrogen dilution raised the CO emission dramatically due to incomplete combustion. These NOx reduction and CO arising phenomena were observed at certain flame temperature of $1500^{\circ}C$ and $1250^{\circ}C$, respectively. As increasing nitrogen dilution, adiabatic flame temperature and combustor liner temperature were decreased and singular points were detected due to change in flame structure such as flame lifting. From the results, the effect of nitrogen dilution on the NOx/CO and flame structure was examined, and the test data will be utilized as a reference to achieve optimal operating condition of the Taean IGCC demonstration plant.

An Experimental Study on the Ambient and High Pressure Combustion Characteristics of Gas Turbine for IGCC (석탄가스화 복합발전용 가스터빈의 상압 및 고압연소특성에 관한 실험적 연구)

  • Lee, Min-Chul;Seo, Seok-Bin;Yoon, Young-Bin
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2011.11a
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    • pp.685-693
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    • 2011
  • In the era of energy climate, IGCC technology is one of the powerful solutions for the demands of new energy with low carbon green growth. The present study is conducted to investigate the combustion characteristics of syngas from the coal gasifier to predict problems when it is fed to the gas turbine. Through high and low combustion tests, we understood that hydrogen is the main reason of NOx emission but easily controled by injecting the dilution of nitrogen. CO emission of syngas was comparable with that of methane and pressure fluctuation of syngas was not significant. The data from this study will be used for the optimization of combustion in the Korea first IGCC plant in 2015.

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Synthesis of Mesoporous Tin Oxide and Its Application as a Gas Sensor (메조세공을 갖는 이산화 주석의 합성 및 가스센서로서의 응용)

  • Kim, Nam-Hyon;Kim, Geon-Joong
    • Applied Chemistry for Engineering
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    • v.18 no.2
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    • pp.142-147
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    • 2007
  • In this study, mesoporous tin oxide was synthesized by sol-gel method using $C_{16}TMABr$ surfactant as a template in a basic condition. The optimum conditions for the synthesis of mesoporous $SnO_2$ were investigated and the obtained samples were characterized by XRD, nitrogen adsorption and TEM analysis. A mesoporous and nanostructured $SnO_2$ gas sensor with Au electrode and Pt heater has been fabricated on alumina substrate as one unit via a screen printing process. Sensing abilities of fabricated sensors were examined for CO and $CH_4$ gases, respectively, at $350^{\circ}C$ in the concentration range of 1~10,000 ppm. Influence of loading amount of palladium impregnated on $SnO_2$ was also tested in detection of those gases. High sensitivity to detecting gases and the fast response speed with stability were obtained with the mesoporous tin oxide sensor as compared to a non-porous one under the same detection conditions.

Experimental Study on Capacity Variation of Paving Materials with TiO2 in Wet Condition (광촉매 이산화티타늄(TiO2)을 혼합한 도로 포장재의 습윤 조건에서의 성능 변화에 관한 실험적 연구)

  • Seo, Dawa;Yun, Tae Sup
    • Journal of the Korean Geotechnical Society
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    • v.32 no.5
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    • pp.49-55
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    • 2016
  • This study aims to present the practical Nitrogen monoxide (NO) removal capacity of cement mortar with Titanium dioxide ($TiO_2$) which is one of the paving materials by considering the environment of pavement in urban areas. NO removal capacity test under designated conditions of humidity of inflow gas and the test with variation of the degree of saturation of specimen were conducted. In the test for humidity, dry specimen is subject to the test and NO removal ratio was observed. Humidity-NO removal ratio curve is a log normal distribution in shape, and the maximum NO removal ratio appears at specific humidity. NO removal capacity test relying on the degree of saturation was carried out with wet specimen to reflect the unsaturated pavement by rainfall and domestic sewage. Wet specimen presents less NO removal capacity than dry specimen and the recovering evolution of NO removal capacity follows evaporation. Moreover, $TiO_2$ under the specific depth of specimen hardly contributes to NO removal capacity.

A Study on the Characteristics of CO Oxidation by NO Poisoning in Pt/TiO2 Catalyst (Pt/TiO2 촉매에서의 NO 피독에 의한 CO 산화반응특성 연구)

  • Kim, Min Su;Kim, Se Won;Hong, Sung Chang
    • Clean Technology
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    • v.25 no.4
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    • pp.296-301
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    • 2019
  • This study was conducted to investigate the characteristics of CO oxidation by NO poisoning in Pt/TiO2 catalyst prepared by wet impregnation method and calcined at 400 ℃. In order to confirm the NO poisoning effect of the Pt/TiO2 catalyst, the change of reaction activity was observed when NO was injected during the CO+O2 reaction where it was ascertained that the CO conversion rate rapidly decreased below 200 ℃. Also, CO conversion was not observed below 125 ℃. Recovery of initial CO conversion was not verified even if NO injection was blocked at 125 ℃. Accordingly, various analyses were performed according to NO injection. First, as a result of the TPD analysis, it was confirmed that NO pre-adsorption in catalyst inhibited CO adsorption and conversion desorption from adsorbed CO to CO2. When NO was pre-adsorbed, it was confirmed through H2-TPR analysis that the oxygen mobility of the catalyst was reduced. In addition, it was validated through FT-IR analysis that the redox cycle (Pt2+→Pt0→Pt2+) of the catalyst was inhibited. Therefore, the presence of NO in the Pt/TiO2 catalyst was considered to be a poisoning factor in the CO oxidation reaction, and it was determined that the oxygen mobility of the catalyst is required to prevent NO poisoning.

Enhancement of Skin Antioxidant and Anti-Inflammatory Potentials of Agastache rugosa Leaf Extract by Probiotic Bacterial Fermentation in Human Epidermal Keratinocytes (프로바이오틱 유산균 발효에 의한 배초향 잎 추출물의 피부 항산화 및 항염증 활성 증대)

  • Lim, Hye-Won;Lee, Yoonjin;Huang, Yu-Hua;Yoon, Ji-Young;Lee, Su Hee;Kim, Kyunghoon;Lim, Chang-Jin
    • Microbiology and Biotechnology Letters
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    • v.45 no.1
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    • pp.35-42
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    • 2017
  • This study aimed to investigate the effects of probiotic fermentation by comparing the skin antioxidant and anti-inflammatory properties of non-fermented (ARE) and fermented (ARE-F) hot water extracts of Agastache rugosa leaves. ARE-F was obtained via ARE fermentation using Lactobacillus rhamnosus HK-9. In vitro, anti-inflammatory properties were evaluated by analyzing the levels of nitric oxide (NO), reactive oxygen species (ROS), and inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-stimulated HaCaT keratinocytes. In vitro antiradical activity was measured using 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Attenuation of LPS-stimulated NO (p < 0.01), ROS (p < 0.001) and iNOS (p < 0.05) levels by ARE-F was significantly stronger than that by ARE in HaCaT keratinocytes. However, no differences were observed between the DPPH radical scavenging activities of ARE and ARE-F. ARE-F possesses enhanced skin antioxidant and anti-inflammatory properties, suggesting that probiotic bacterial fermentation can be considered an effective tool for augmenting some pharmacological properties of A. rugosa leaves. In brief, the skin antioxidant and anti-inflammatory potentials of A. rugosa leaf extract are augmented by the fermentation with L. rhamnosus HK-9, a probiotic bacterium.

Analysis of statistical models for ozone concentrations at the Paju city in Korea (경기도 파주시 오존농도의 통계모형 연구)

  • Lee, Hoon-Ja
    • Journal of the Korean Data and Information Science Society
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    • v.20 no.6
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    • pp.1085-1092
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    • 2009
  • The ozone data is one of the important environmental data for measurement of the atmospheric condition of the country. In this article, the Autoregressive Error (ARE) model and Neural Networks (NN) model have been considered for analyzing the ozone data at the northern part of the Gyeonggi-Do, Paju monitoring site in Korea. In the both ARE model and NN model, seven meteorological variables and four pollution variables are used as the explanatory variables for the ozone data set. The seven meteorological variables are daily maximum temperature, wind speed, relative humidity, rainfall, dew point temperature, steam pressure, and amount of cloud. The four air pollution explanatory variables are Sulfur dioxide ($SO_2$), Nitrogen dioxide ($NO_2$), Cobalt (CO), and Promethium 10 (PM10). The result showed that the NN model is generally better suited for describing the ozone concentration than the ARE model. However, the ARE model will be expected also good when we add the explanatory variables in the model.

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Modulatory Effects of 21 kinds of Medicinal Herbs Including Herba Pogostemi (Agastache rugosa) on Nitric Oxide Production in Macrophage Cell line RAW 264.7 cells (곽향(Agastache rugosa)을 포함한 21종의 한약재가 대식세포주 RAW 264.7 세포의 nitric oxide(NO) 생산 조절에 미치는 효과)

  • Kim, Seung-Hyun;Kang, Mi-Young;Nam, Seok-Hyun
    • Applied Biological Chemistry
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    • v.48 no.4
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    • pp.411-417
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    • 2005
  • Aqueous extracts were prepared from 21 medicinal herbs including Herba Pogostemi (Agastache rugosa) to examine their modulatory effects on NO production in mouse macrophage cell line RAW264.7 cells. While almost all medicinal herb extracts failed to show marked scavenging activities to NO produced by LPS stimulation, only Herba Pogostemi showed a rather strong induction of NO production in RAW264.7 cells without stimulation with LPS. When we treated the cell with $200{\mu}M\;of\;N^G-monomethyl-L-arginine\;(N^GMMA)$, a NOS2 inhibitor, a significant reduction in NO production could be observed. Moreover, a treatment of $100{\mu}M$ pyrrolidine dithiocarbamate (PDTC) led to about a 79% reduction of NO production. These results demonstrated that the aqueous extract of Herba Pogostemi might provide a second signal for the expression of NOS2 in RAW264.7 cells, and suggested that Herba Pogostemi induces NO production through L-argininedependent pathway.