• The Journal of Korean Society for Radiation Therapy
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• v.18 no.2
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• pp.89-96
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• 2006

Purpose: To study effectiveness of heterogeneity correction of internal-body inhomogeneities and patient positioning immobilizers in dose calculation, using images obtained from CT-Simulator. Materials and Methods: A water phantom($250{\times}250{\times}250mm^3$) was fabricated and, to simulate various inhomogeneity, 1) bone 2) metal 3) contrast media 4) immobilization devices(Head holder/pillow/Vac-lok) were inserted in it. And then, CT scans were peformed. The CT-images were input to Radiation Treatment Planning System(RTPS) and the MUs, to give 100 cGy at 10 cm depth with isocentric standard setup(Field Size=$10{\times}10cm^2$, SAD=100 cm), were calculated for various energies(4, 6, 10 MV X-ray). The calculated MUs based on various CT-images of inhomogeneities were compared and analyzed. Results: Heterogeneity correction factors were compared for different materials. The correction factors were $2.7{\sim}5.3%$ for bone, $2.7{\sim}3.8%$ for metal materials, $0.9{\sim}2.3%$ for contrast media, $0.9{\sim}2.3%$ for Head-holder, $3.5{\sim}6.9%$ for Head holder+pillow, and $0.9{\sim}1.5%$ for Vac-lok. Conclusion: It is revealed that the heterogeneity correction factor calculated from internal-body inhomogeneities have various values and have no consistency. and with increasing number of beam ports, the differences can be reduced to under 1%, so, it can be disregarded. On the other hand, heterogeneity correction from immobilizers must be regarded enough to minimize inaccuracy of dose calculation.

• Proceedings of the Korean Society of Medical Physics Conference
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• 2003.09a
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• pp.65-65
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• 2003

목적 : 방사선치료기술이 날로 발전함에 따라 방사선치료계획시스템에 대한 주기적인 정도관리의 필요성은 증대하고 있으나, 국내 실정에 적합한 표준화된 정도관리절차서가 없는 실정이다. 따라서 본 연구에서는 방사선치료계획용 시스템에 대한 정도관리용 고체팬톰을 제작하여 주기적인 정도관리 활용 및 절차서를 제시하고자 한다. 대상 및 방법 : 체윤곽 보정을 위한 삼각기둥 모형 (30cm$\times$30cm$\times$5cm, 30cm$\times$15cm$\times$5$\times$) 및 정형ㆍ부정형, 불균질 측정이 가능한 물등가고체팬톰을 제작하였고, 컴퓨터단층촬영(AcQsim)을 통해 영상을 얻었으며, RTPS(AcQplan)에 입력하여 영상 내 기준점에서의 선량값을 계산하였다. RTPS를 통해 계산된 값의 평가를 위해 동일한 조건하에서 각 기준점에 대한 실제 측정을 이온함을 이용하여 측정하였다. 평가 항목으로는 정방형 조사면, 부정형 조사면, 쐐기 조사면, 불균질 물질 보정, 사방향 조사 등에 대해서 알고리즘별로 수행하였다. 결과 : RTPS를 이용하여 계산된 값과 실제 측정한 값을 비교하여 RTPS의 정확성을 평가한 결과로 합성의 불확도 허용 기준 (3%), 선속 중심축 상에서의 허용 기준 (2%) 등, 선진 각국 및 각 학회에서 권고하고 있는 허용 범위 내에서 잘 일치하였다. 결론 : RTPS는 측정된 심부선량과 선량분포 등 물리적인 인자에 의존하는 제한성이 있고, 실제로 선량계산 알고리즘과 기하학적 변화에 따라 계산값과 측정값 간에 차이가 발생할 수 있었다. 실제 인체의 체윤곽 불균일성과 불균질성을 모사한 팬톰을 제작하여 이용함으로써 다양한 RTPS간의 비교를 통한 치료 선량의 정확성을 평가하고, 방사선 치료의 원활하고 정확한 수행을 위해 실용적이고, 보편적인 치료계획 시스템의 정도관리 방법과 절차서를 수립하는데에 유용할 것으로 사료된다.

• Journal of Radiation Protection and Research
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• v.23 no.3
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• pp.139-147
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• 1998

Purpose: Tissue inhomogeneity such as lung affects tumor dose as well as transmission dose in new concept of on-line dosimetry which estimates tumor dose from transmission dose using the new algorithm. This study was carried out to confirm accuracy of correction by tissue density in tumor dose estimation utilizing transmission dose. Methods: Cork phantom (CP, density $0.202\;gm/cm^3$) having similar density with lung parenchyme and polystyrene phantom (PP, density $1.040\;gm/cm^3$) having similar density with soft tissue were used. Dose measurement was carried out under condition simulating human chest. On simulating AP-PA irradiation, PPs with 3 cm thickness were placed above and below CP, which had thickness of 5, 10, and 20 cm. On simulating lateral irradiation, 6 cm thickness of PP was placed between two 10 cm thickness CPs additional 3 cm thick PP was placed to both lateral sides. 4, 6, and 10 MV x-ray were used. Field size was in the range of $3{\times}3$ cm through $20{\times}20$ cm, and phantom-chamber distance (PCD) was 10 to 50 cm. Above result was compared with another sets of data with equivalent thickness of PP which was corrected by density. Result: When transmission dose of PP was compared with equivalent thickness of CP which was corrected with density, the average error was 0.18 (${\pm}0.27$) % for 4 MV, 0.10 (${\pm}0.43$) % for 6 MV, and 0.33 (${\pm}0.30$) % for 10 MV with CP having thickness of 5 cm. When CP was 10 cm thick, the error was 0.23 (${\pm}0.73$) %, 0.05 (${\pm}0.57$) %, and 0.04 (${\pm}0.40$) %, while for 20 cm, error was 0.55 (${\pm}0.36$) %, 0.34 (${\pm}0.27$) %, and 0.34 (${\pm}0.18$) % for corresponding energy. With lateral irradiation model, difference was 1.15 (${\pm}1.86$) %, 0.90 (${\pm}1.43$) %, and 0.86 (${\pm}1.01$) % for corresponding energy. Relatively large difference was found in case of PCD having value of 10 cm. Omitting PCD with 10 cm, the difference was reduced to 0.47 (${\pm}$1.17) %, 0.42 (${\pm}$0.96) %, and 0.55 (${\pm}$0.77) % for corresponding energy. Conclusion When tissue inhomogeneity such as lung is in tract of x-ray beam, tumor dose could be calculated from transmission dose after correction utilizing tissue density.