• Title/Summary/Keyword: 인지저하

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Physical and Mental Health Status and Its Related Factors among Centenarians in Korea (100세 이상 고령자의 신체적·정신적 건강수준 및 관련 요인)

  • Song, Young-Su;Kim, Tae-Baek;Bae, Nam-Kyou;Kim, Ki-Hyang;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.5
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    • pp.268-277
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    • 2017
  • This study was performed to determine the level of physical health(ADL, IADL) and mental health (cognitive impairment, dementia) among centenarians and to find the related factors. The study subjects were 268 centenarians who received medical check-ups from the National Health Insurance Corporation during 2011-2014. From the results, the factors that significantly influenced the ADL of the study subjects were gender, residential area, IADL, cognitive impairment and dementia. ADL and cognitive impairment were selected as the influencing factors of IADL, smoking status, ADL and IADL were selected as the influencing factors of cognitive impairment, and gender and ADL were selected as the influencing factors of dementia. These results suggested that the levels of physical and mental health of the centenarians were significantly affected by socio-demographic characteristics and health-related variables. Especially, the levels of physical and mental health were decreased with the poor group of health-related variables such as smoking, alcohol drinking and regular exercise.

Main Cause of the Interference between Visual Search and Spatial Working Memory Task (시각 탐색과 공간적 작업기억간 상호 간섭의 원인)

  • Ahn Jae-Won;Kim Min-Shik
    • Korean Journal of Cognitive Science
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    • v.16 no.3
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    • pp.155-174
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    • 2005
  • Oh and Kim (2004) and Woodman and Lurk (2004) demonstrated that spatial working memory (SWM) load Interfered concurrent visual search and that search process also impaired the maintenance of spatial information implying that visual search and SWM task both require access to the same limited-capacity mechanism. Two obvious possibilities have been suggested about what this shared limited-capacity mechanism is: common demand for attention to the locations where the items f9r the two tasks were presented (spatial attention load hypothesis), and common use of working memory to maintain a record of locations have been processed(SWM load hypothesis). To test these two hypothetical explanations, Experiment 1 replicated the mutual interference between visual search and SWM task in spite of difference of procedure with preceding researches; possible areas where the items for two tasks were presented were not separated. In Experiment 2, we presented the items for visual search either in the same quadrants where the items for SWM task had appeared (same-location rendition) or in the different quadrants (different-location condition). As a result, search efficiency was more impaired in the different-location condition than in the same-location condition. The memory accuracy was worse in the different-location rendition than in the same-location rendition. Overall results of study indicate that the mutual interference between SWM and visual search might be related to the overload of spatial attention, but not to that of SWM.

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Characteristics of Psychiatric Consultation between Presenile and Senile Inpatients (초로기와 노년기 입원환자에 대한 정신건강의학과 자문의 특성)

  • Lee, Ji Woong;Cheon, Jin Sook;Kim, Kang Ryul;Kim, Hyun Seuk;Oh, Byoung Hoon
    • Korean Journal of Psychosomatic Medicine
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    • v.21 no.2
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    • pp.114-121
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    • 2013
  • Objectives: The aim of this study was to know differences of characteristics between presenile and senile patients who were consulted to the department of psychiatry during medical-surgical admission. Methods: The demographic and clinical data obtained from the medical records of psychiatric consultation in the presenile inpatients with age 50 to 64 years(N=162) and those of the senile inpatients with age over 65 years(N=171) were reviewed and compared. Results: 1) The most common chief complaints for psychiatric consultation in presenile patients were somatic symptoms, anxiety and sleep disturbance in order, while cognitive decline, clouded consciousness and depressed mood were most common in senile patients with statistical significance. 2) The most frequent psychiatric diagnoses after consultation in presenile patients were delirium, mood disorder and substance use disorder in order, while delirium, mood disorder and major neurocognitive disorder were most frequent in senile patients with statistical significance. 3) There were no significant difference in numbers of physical illnesses, while numbers of therapeutic drugs for them were more in senile patients. Conclusions : Our study found significant differences between presenile and senile patients on psychiatric symptoms and diagnoses in geropsychiatric consultation. Therefore, more subdivided age-specific approach seems to be needed for the geropsychiatric consultation activities.

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The Influence of Participation of Physical Activity in Adolescence and Senescence Adults on Affective Cognition (청년기·노년기 성인의 신체활동 참여가 정서인지에 미치는 영향)

  • Yoon, Byungtak;Ryu, Kwangmin;Kim, Jingu
    • Science of Emotion and Sensibility
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    • v.20 no.4
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    • pp.41-54
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    • 2017
  • Physical activity has positive effects on cognitive functions by aging. However, it is rare to find research that have scientifically investigated the effects on the affective-cognitive function. Thus, this study aims to brain-scientifically research its effects of physical activity on the affective-cognitive function of adults in adolescence and senescence. As subjects of this study, a total of 60 males adults in D region were selected, and then equally divided into four groups of young exercise group(25~35y/o), young non-exercise group(26~35y/o), old exercise group(60~70y/o), and old non-exercise group(60~70y/o). As experiment tools, the EEG measuring equipment and International Affective Picture System(IAPS) were used. The experiment of this study used an affective-cognitive task where subjects pressed a button depending on emotional valence(positive, neutral, negative) shown in the pictures. During the task, EEG measured eight areas(Fp1, Fp2, Fz, C3, C4, Cz, T3, T4) out of brain areas in accordance with the international 10-20 electrode system, EEG was measured. For statistical analysis, a three-way ANOVA on $4(group){\times}3(stimulus){\times}8(area)$ was conducted. The results showed main effects of group in both reaction time and accuracy, and also in the latency of P3. And there was an interaction between group and stimulus the amplitude of P3. In conclusion, Physical activity has positive effects on the affective-cognitive function of people in adolescence and senescence.

Differentiation of expression on 5-day workweek concerned advertising -focused on lifestyle and cognitive inconsistency perspective (주5일 근무제 관련광고의 표현차별화 방식-라이프 스타일 및 인지 불균형의 관점에서)

  • 이현우
    • Archives of design research
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    • v.17 no.1
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    • pp.25-36
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    • 2004
  • The purpose of this study is to analyse and interpret the way of differentiated expression and changing creative trend following 5-day workweek which has been recently adopted. For this aim 11 pieces of distinctive advertising text were analysed. The criteria for selection of analysing text were relativeness with 5-day workweek and cognitive inconsistency. These texts were negative phrases, exaggerated expression, and excessively humorous appeals. The study revealed the followings: First, 5-day workweek concerned advertising texts were considered as high attention getting and successful in stimulating advertising audiences' curiosity by using the elements opposing the value and belief system formed in the existing audience. Second, consumption-driving lifestyle was found in most expressions for credit cards advertising. Third, hedonic need-oriented lifestyle was typical in young consumer products category. Fourth, family centered lifestyle emphasized meaning of rest and solidarity of family.

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A feasibility study on new stimulation method in fMRI language examinations using custom designed images (기능적 자기공명영상의 언어기능검사 시 image를 이용한 자극방법의 타당성 연구)

  • Choi, Kwan-Woo;Son, Soon-Yong;Jeong, Mi-Ae;Min, Jung-Whan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.11
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    • pp.5005-5011
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    • 2011
  • The purpose of this work is to know the validity of a new stimulation method in cognitive functional imaging using custom-designed images correspond to words or syllables improving the shortcomings of existing method using text. From March 2011 to May five Subjects in need of language related functional MRI scanning were selected and both of text stimulating method and image stimulating method sacanning were carried out three times each. Using 3.0T Philps MRI machine and Invivo Co's Eloquence system, data acquisition was performed with EPI-BOLD technique. Post processing was performed with SPM 99 while the activated signals were determined within 95 percent confidence level.The number of activation clusters and the activation ratio inside ROI were compared. As as result, all of the subject showed activation inside Broca area but it did not have statistical significance. In conclusion, the image sitimulation method has potential because image itself is a common means of recognition and it can be recognised easily even if there language barrier. This stimulation method can be applied to replacing the exising scanning method especially in the elderly, infants, foerigners who may not fully understand about the examination.

The Effect of Treadmill Exercise and Environmental Enrichment on Cognitive Function, Muscle Function, and Levels of tight junction protein in an Alzheimer's Disease Animal Model (트레드밀 운동 및 환경강화가 알츠하이머 질환 동물 모델의 인지기능, 근 기능 및 밀착연접 단백질 수준에 미치는 영향)

  • Hyun-Seob Um;Jong-Hwan Jung;Tae-Kyung Kim;Yoo-Joung Jeon;Joon-Yong Cho;Jung-Hoon Koo
    • Journal of the Korean Applied Science and Technology
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    • v.41 no.1
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    • pp.58-68
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    • 2024
  • The purpose of this study was to investigate the effects of treadmill exercise treadmill exercise (TE) and environmental enrichment (EE) interventions on cognitive function, muscle function, and the expression of tight junction proteins in an Alzheimer's disease (AD) animal model. To create the AD animal model, aluminum chloride (AlCl3) was administered for 90 days (40mg/kg/day), while simultaneously exposing the animals to TE (10-12m/min, 40-60min/day) or EE. The results showed that cognitive impairment and muscle dysfunction induced by AlCl3 administration were alleviated by TE and EE. Furthermore, TE and EE reduced the increased expression of β-amyloid(Aβ), alpha-synuclein, and tumor necrosis factor-α (TNF-α) proteins observed in AD pathology. Additionally, TE and EE significantly increased the expression of decreased adhesive adjacent proteins (Occludin, Claudin-5, and ZO-1) induced by AlCl3 administration. Lastly, correlation analysis between Aβ protein and tight junction proteins showed negative correlations (Occludin: r=-0.853, p=0.001; Claudin-5: r=-0.352, p=0.915; ZO-1: r=-0.424, p=0.0390). In conclusion, TE or EE interventions are considered effective exercise methods that partially alleviate pathological features of AD, improving cognitive and muscle function.

A Study on Analysis of Variant Factors of Recognition Performance for Lip-reading at Dynamic Environment (동적 환경에서의 립리딩 인식성능저하 요인분석에 대한 연구)

  • 신도성;김진영;이주헌
    • The Journal of the Acoustical Society of Korea
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    • v.21 no.5
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    • pp.471-477
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    • 2002
  • Recently, lip-reading has been studied actively as an auxiliary method of automatic speech recognition(ASR) in noisy environments. However, almost of research results were obtained based on the database constructed in indoor condition. So, we dont know how developed lip-reading algorithms are robust to dynamic variation of image. Currently we have developed a lip-reading system based on image-transform based algorithm. This system recognize 22 words and this word recognizer achieves word recognition of up to 53.54%. In this paper we present how stable the lip-reading system is in environmental variance and what the main variant factors are about dropping off in word-recognition performance. For studying lip-reading robustness we consider spatial valiance (translation, rotation, scaling) and illumination variance. Two kinds of test data are used. One Is the simulated lip image database and the other is real dynamic database captured in car environment. As a result of our experiment, we show that the spatial variance is one of degradations factors of lip reading performance. But the most important factor of degradation is not the spatial variance. The illumination variances make severe reduction of recognition rates as much as 70%. In conclusion, robust lip reading algorithms against illumination variances should be developed for using lip reading as a complementary method of ASR.

A Study of Image Characteristics due to Focus-Grid and Head Phantom Decentering from the Armorphos Silicon Thin Film Transistor Detector the Fixed Focus-Grid is Applied (고정식 초점형 격자가 적용된 비정절 실리콘 평판형 검출기에서 초점-격자와 두부 팬텀의 중심 변위에 의한 화질 특성에 관한 연구)

  • Choi, Jun-Gu;Kim, Byeong-Gi;Cha, Seon-Hwa;Kim, Gyeong-Su
    • Korean Journal of Digital Imaging in Medicine
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    • v.9 no.1
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    • pp.7-15
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    • 2007
  • This study aim to investigate image characteristics due to focus-grid and head phantom decentering from the armorphos silicon thin film transistor detector the fixed focus-grid is applied, wish to propose right use method of digital medical equipment. Acquired image according to focus-grid and head phantom position decentering using head phantom on armorphos silicon thin film transistor detector the fixed focus-grid is applied. acquired image evaluate pixel value, histogram, plot profile, surface plot using NIB (Image J) image analysis program and compared decentering image with standard image. Mean value and standard deviation value of focus-grid lateral decentering and duplex decentering of focus-grid and head phantom decreased by ratio, consequently increase of horizontality, diagonal decentering. also, deteriorated contrast of image because frequency of high pixel value decreases fairly. according increases decentering, image distortion phenomenon was increase, by next time, pixel mean value of head phantom decentering was no big change but horizontality, diagonal, mean value and standard deviation value of pixel decreased by ratio. Even if increase pixel noise of image because wide latitude and post processing ability of digital detector, radiotechnologist can not recognize. Therefore, radiotechnologist must recognize correctly the photographing factors which increases pixel noise on the grid system installation digital detector and should exam.

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The role of hipocampus and posterior pariental cortex in acquisition of spatial learnig (공간기억의 습득에 있어서 해마와 두정엽후위의 역할)

  • Shim, Beom;Leem, Joong-Woo;Nam, Taick-Sang;Paik, Kwang-Se;Lee, Bae-Hwan;Park, Yong-Gou
    • Korean Journal of Cognitive Science
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    • v.10 no.4
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    • pp.41-50
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    • 1999
  • It is widely known that the hippocampus plays an important role in spatial memory. Recent studies have suggested that the posterior parietal cortex (PPC) is involved in spatial memory. However it is unclear whether the PPC is involved in w working memory or reference memory of spatial learning. The purpose of the present study was to determine contribution of the hippocampus and the PPC to spatial working memory and acquisition of reference memory. Using an eight-arm radial maze in which e each arm was baited. working memory was tested by measuring rat's ability to remember arms they had visited. Reference memory was tested by measuring rat's ability to avoid visiting four consistently unbaited arms. Effects of hippocampal or PPC lesion on working memory or acquisition of reference memory in radial-arm maze learning were investigated Working memory was impaired by hippocampal lesion whereas not affected by PPC lesion. Acquisition of reference memory was impaired by lesion in either site. The results suggest that the hippocampus plays an important role in the spatial working memory while both the hippocampus and the PPC contribute to the acquisition of spatial reference memory.

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