• Title/Summary/Keyword: 인간이동

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A Case of a 46,XX Male with SRY Gene (SRY 유전자를 가진 46,XX 남성 1례)

  • Min, Jeong-Yong;Lee, Dong-Suk;Cho, Soo-Kyung;Park, So-Hyun;Lee, Soo-Min;Baek, Min-Kyung;Kim, Ki-Chul;Hwang, Do-Yeong
    • Journal of Genetic Medicine
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    • v.5 no.2
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    • pp.145-149
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    • 2008
  • 46,XX male is a rare sex constitution characterized by the development of bilateral testis in persons who lack a Y chromosome. Manifestations of 46,XX males are usually hypogonadism, gynecomastia, azoospermia, and hyalinations of seminiferous tubules. The incidence of XX male reversal is approximately 1 in 20,000 male neonates. The SRYgene is located at the short arm of the Y chromosome(Yp11.31) and codes for testis determining factor in humans. Here, the patient, who presented with a normal male phenotype, was referred for azoospermia. Conventional cytogenetic analysis showed a 46,XX karyotype. Quantitative fluorescent polymerase chain reaction(QF-PCR) and Multiplex PCR studies identified SRY gene. And, Fluorescence In Situ Hybridization(FISH) confirmed the SRY gene on the distal short arm of chromosome X. We identified the SRY gene on the distal short arm of chromosome X by molecular cytogenetic and molecular analyses. Therefore, molecular-cytogenetics and molecular studies were proved to be clinically useful adjunctive tool to conventional prenatal cytogenetic analysis.

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A Study of Drug Content and Cell Cytotoxicity of Paclitaxel-eluting Stents Coated with Various Biopolymer (다양한 생체고분자로 코팅된 Paclitaxel Eluting Stent의 약물함량과 세포독성 연구)

  • Kim, Dong-Gon;Shin, Il-Gyun;Kim, Gi-Han;Kim, Seong-Hyeon;Lee, Ju-Ho;Ki, Byoyng-Yun;Nah, Jae-Woon;Suh, Tae-Suk;Kim, Sang-Ho
    • Progress in Medical Physics
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    • v.20 no.3
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    • pp.125-131
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    • 2009
  • In this study, the paclitaxel eluting stent (PES) was prepared by coating a biliary stent with paclitaxel using various biopolymer such as poly (vinyl acetate) (PVAc), poly (lactic-co-glycolic acid) (PLGA), Silicone rubber for restenosis prevention in gastrointestinal disease by a dip-coating method. Drug contents of PES were increased as surface area of stent, concentration and molecular weight of coating polymer increase. In $^1H-NMR$ specta, we know that drug did not change by confirming specific peaks of paclitaxel in PES. As shown in SEM image, PES prepared using various biopolymer is coated clearly and regularly except Silicone rubber coating polymer. In in vitro cell cytotoxicity test, bare stent showed low cytotoxic effect against CT-26 colon carcinoma cell line on 3 day. However, PES coated with PLGA 502H showed the highest cytotoxicity because PLGA 502H is biodegradable polymer and has less molecular weight than other coating polymer. These results suggest that PES coated various biopolymer can be prevented restenosis in gastrointestinal disease.

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Historic Development of Navajo Textiles - Focus on the Classic Period - (Navajo 직물의 역사적 발달에 대한 연구 - 고전시대를 중심으로 -)

  • 정미실
    • Journal of the Korean Society of Costume
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    • v.45
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    • pp.5-16
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    • 1999
  • 본 연구의 목적은 Navajo 직물의 역사적 발달을 고전시대를 중심으로 살펴보고 특히 외부영향에 따른 직물의 변화를 고찰하는데 있다. 구체적으로 1) 고전시대의 전통적인 직물은 어떻게 발달하였는가\ulcorner 2) 고전시대 직물의 전통적 요소와 외부영향요인은 어떤 점이 다른가\ulcorner 예 초점을 맞추었다. 연구방법은 아메리카 인디언의 이동,문화 Navajo 직조 및 직물에 대한 문헌을 바탕을 조사하였고 아리조나 주립박물과 아리조나 역사 박물관을 방문하였으며 박물관 안에 있는 전문가들의 조언을 듣고 연구의 자료를 보완하였다. 또 비교 미학적 차원에서 고전시대 navajo 직물의 전통적 요소와 외부영향 요인을 분석하였고 외부영향을 받은 직물의 예를 시각적자료로 제시하였다. 이연구는 인디언직물에 대한 이해, 고전시대. Navajo 직물의 문헌고찰을 통한 민족의복의 문화적측면에 기여할수 이고 현대적 감각을 지닌 Navajo 직물을 한국직물에 접목 응용하는데 도움을 줄수 있다 본 연구의 결과는 다음과 같다. 1. Navajo 직물을 고전, 전환, 양탄자 시대로 구분되었고. 이중에서 고전시대가 navajo 직물의 특성을 가장 잘 나타내었으며 발달된 직조기술을 보였다. Navajo인들의 직조기술은 1863년경 최고조에 달했다. Navajo 직물의 디자인 주제로 주로 인간을 둘러싸고 있는 환경에서 얻어졌고 이것들은 직선의 기하학적 형태로 구체화되었다. 또한 직물에 표현된 색도 자연과 밀접한 관련성을 갖는 있었다. 2. Navajo 직물의 주용한 용도는 여성용 드레스, 남성용 셔츠는 어깨에 걸치는 두르개였다. 여성용 드레스는 동일한 크기의 직물의 두장을 직조한 후에 꿰매었고 남성용 셔츠는 머리가 들어갈수 있는 구멍이 있는 장방형 판쵸 스타일이었다. 어깨에 걸치는 두르개는 여성의 경우 가운데가 검은색이고 가장자리가 푸른색인형태오 흰색과 붉은 색이 교대로 나타나는 형태의 2가지가 있었고 남성용은 고전시대의 대표라고 일컬어지는 족장 두르개였다. 3. Navajo 직물은 외부의 영향을 받아 많은 변화를 가져왔다. 즉 스페인 사람들로 인하여 면 섬유대신 양모섬유를 사용하게 되었고 전통적 모양과 다른직물이 출현하게 되었다. 또한 인디고 염류, 색소니 실, 바에타 직물의 도입으로 다양한 색상의 표현이 가능해졌고 이와 관련하여 다이아몬드 십자형 톱니형 무늬드이 나타나게 되었다. 4, 고전시대를 대표하는 직물로 족장 두르개, 쇼올, 안장덮개를 들수 있으며 이 직물들에서 뚜렷하게 외부영향 요인을볼수 있다. 즉 족장 두르개의 가장 정교한 단계에서 다이아몬드 무늬가 가장가리 가운데 모서리에 위치하여 9지점 배치를 이룬 것 쇼올의 경우 폭보다 길이가 긴 형태의 비전통적 모습을 나타낸 것 안장덮개에서 보여지는 여덟포인트 별 무늬도 외부의 영향을 받은예이다. 뛰어난 직조기술로 유명한 navajo인들은 변화에 잘 적응하는 특성을 갖고 있었다. 외부의 영향을 그들은 긍정적으로 받아들였고 자기 자신들의 필요에 맞도록 수정하여 정체감을 잃지 않으면서도 문화를 발전시켰다. 따라서 고전시대의 Navajo 직물은 고유적 요인과 외래적 요인의 조화를잘 나타내고 있으며 디자인의 탁월함이 세련됨 천연염료와 인조염료의 배\ulcorner에 의한 색상의 우월성 등으로 오늘까지 높이 평가되고있다.

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Estimating a Range of Lane Departure Allowance based on Road Alignment in an Autonomous Driving Vehicle (자율주행 차량의 도로 평면선형 기반 차로이탈 허용 범위 산정)

  • Kim, Youngmin;Kim, Hyoungsoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.15 no.4
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    • pp.81-90
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    • 2016
  • As an autonomous driving vehicle (AV) need to cope with external road conditions by itself, its perception performance for road environment should be better than that of a human driver. A vision sensor, one of AV sensors, performs lane detection function to percept road environment for performing safe vehicle steering, which relates to define vehicle heading and lane departure prevention. Performance standards for a vision sensor in an ADAS(Advanced Driver Assistance System) focus on the function of 'driver assistance', not on the perception of 'independent situation'. So the performance requirements for a vision sensor in AV may different from those in an ADAS. In assuming that an AV keep previous steering due to lane detection failure, this study calculated lane departure distances between the AV location following curved road alignment and the other one driving to the straight in a curved section. We analysed lane departure distance and time with respect to the allowance of lane detection malfunction of an AV vision sensor. With the results, we found that an AV would encounter a critical lane departure situation if a vision sensor loses lane detection over 1 second. Therefore, it is concluded that the performance standards for an AV should contain more severe lane departure situations than those of an ADAS.

An Analysis of Change in the Employment Structure Data Caused by the Industrial Revolution (산업혁명에 따른 고용구조 변화 데이터 분석)

  • Kim, JeaYoung;Kim, Hyunsoo
    • Journal of Service Research and Studies
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    • v.7 no.3
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    • pp.57-70
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    • 2017
  • It is anticipated that the employment structure of the whole industry will change drastically as the Fourth Industrial Revolution era arrives. Particularly, there are numerous reseraches that the development of artifical intelligence will promote automation causing jobs in manufacturing industry to decrease; thus, the economy will be reorganized with service-centered jobs, which heavily depend on human ability. This study was conducted to verify the trend-forecasting model based on the theoretical analysis. We analyzed the change in employment structure over the past decades in each country and period to gain insights from the changes in the employment structure caused by the Fourth Industrial Revoltion. The results of this study are as follows: First, we investigaed whether the current economy is moving along the U-shaped model suggested by an existing researcher. As a result of the analysis, the data substantiated that the change of the employment structure is moving along the U-shaped model. It is also suggested that this U-shaped trend is expected to accelerate in the era of the Fourth Industrial Revolution. In the future, more accurate data analyses are needed to verify the model, and additional researches on the change in the employment structed is also needed.

A Study on the Makeup Trend of Digital Communication Environment (디지털 커뮤니케이션 환경의 메이크업 트렌드 연구)

  • Barng, Kee-Jung
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.37 no.1
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    • pp.23-36
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    • 2011
  • The purpose of this study is to make theoretical examinations into the makeup trend shown in digital communication environment and thereby determine potential associations of makeup trend with digital communication environment and characterize said trend, so that it can provide reference materials required for follow-up studies. This study comes to the following findings: First, it is found that there are sociocultural characteristics of digital communication environment, such as interactivity, technology-orientedness, sentiment-orientedness and mixture of time and space. Secondly, it is found that trends developed in makeup fall categorically into interactivity, virtuality, amusement and mobility. Thirdly, it is found that each type of digital communication adopts a mixture and juxtaposition of contemporary styles or categories with traditional ones through eclectic combination based on open-minded and horizontal ideas. Fourthly, it is found that a trend from digital communication environment doesn't coincide perfectly with any makeup trend, but the former trend works interactively and organically with the latter trend on the basis of homogeneity and similarity within a general framework that represents external esthetics of human being. With the creation of digital communication environment, our contemporary society forms as the complex phenomena of digital society in a combination and destruction of different categories beyond any certain international boundary, so that a hybrid tendency appears in contemporary makeup trend as well. Based on these findings, this study has its implications in the sense that it gives a new viewpoint based on design, formative characteristics and expression styles of makeup, and also provides useful reference materials for related industrial sectors.

Seasonal Monitoring of Residual Veterinary Antibiotics in Agricultural Soil, Surface Water and Sediment Adjacent to a Poultry Manure Composting Facility (계분 퇴비화 시설 인근 농경지 토양, 지표수 및 저질토의 계절별 잔류 항생물질 모니터링)

  • Lee, Sang-Soo;Kim, Sung-Chul;Kim, Kwon-Rae;Kwon, Oh-Kyung;Yang, Jae-E.;Ok, Yong-Sik
    • Korean Journal of Environmental Agriculture
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    • v.29 no.3
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    • pp.273-281
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    • 2010
  • Concentration of antibiotics including a tetracycline group (TCs) of tetracycline (TC), chlortetracycline (CTC), and oxytetracycline (OTC), a sulfonamide group (SAs) of sulfamethoxazole (SMX), sulfathiazole (STZ), and sulfamethazine (SMT), an ionophore group (IPs) of lasalocid (LSL), monensin (MNS), and salinomycin (SLM), and a macrolide group (MLs) of tylosin (TYL) was determined from samples collected from the agricultural soil, stream water, and sediment. For the agricultural soil samples, the concentration of TCs had the highest value among all tested antibiotic's groups due to its high accumulation rate on the surface soils. The lower concentrations of SAs in the agricultural soils may be resulted from its lower usage and lower distribution coefficient (Kd) compared to TCs. The concentration of TCs in stream water was significantly increased through June to September. It would be likely due to soil loss during an intensive rainfall event and a reduction of water level after the monsoon season. A significant amount of TCs in the sediment was also detected due to its accumulation from runoff, which occurred by complexation of divalent cations, ion exchange, and hydrogen bonding among humic acid molecules. To ensure environmental or human safety, continuous monitoring of antibiotics residues in surrounding ecosystems and systematic approach to the occurrence mechanism of antibiotic resistant bacteria are required.

An Empirical Study of SNS Users' Switching Intention Toward Closed SNS (SNS 이용자의 폐쇄형 SNS로의 전환의도에 영향을 미치는 요인에 관한 연구)

  • Park, Hyunsun;Kim, Sanghyun
    • Information Systems Review
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    • v.16 no.3
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    • pp.135-160
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    • 2014
  • Most Social Network Service (SNS) provide online chat, video and file sharing, blogging and others. Because of this advantage, people depend on SNS to communicate with others. However, recently SNS encourage people to reveal too much information broadly so SNS users are concerned about privacy invasion and data spill. They also feel fatigue in process of touching people they don't know while using SNSs. That is the reason why they attempt to switch from opened SNS to Closed SNS. Therefore, the purpose of this study is to empirically investigate and analyze the effect of the factors on the SNS users' switching behavior when using SNS. To accomplish this purpose, this research adopted "Push-Pull-Mooring (PPM)" framework. The PPM is proposed by population geologist, who used it to explain the incentives of demographic migration. Following PPM model, this research empirically examines the three categories of antecedents for SNS switching intention toward closed SNS: push (i.e., weak connection, privacy concern, relative complexity), pull (i.e., enjoyment, belongingness, peer influence), mooring (i.e., SNS fatigue, user resistance) factors. The survey was conducted for 285 users on SNS communities in Korea. The results of this study are as follows; First, wear connection and privacy concern are significantly related to SNS switching intention. Second, enjoyment and belongingness are significantly related to SNS switching intention. Finally, the results show that SNS fatigue has a moderating effect on the links between push factors and SNS switching Intention. Also, user resistance has a moderating effect on the links between pull factors and SNS switching Intention. These findings contribute to the SNS literature both theoretically and practically.

Design and Implementation of a Real-Time Lipreading System Using PCA & HMM (PCA와 HMM을 이용한 실시간 립리딩 시스템의 설계 및 구현)

  • Lee chi-geun;Lee eun-suk;Jung sung-tae;Lee sang-seol
    • Journal of Korea Multimedia Society
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    • v.7 no.11
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    • pp.1597-1609
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    • 2004
  • A lot of lipreading system has been proposed to compensate the rate of speech recognition dropped in a noisy environment. Previous lipreading systems work on some specific conditions such as artificial lighting and predefined background color. In this paper, we propose a real-time lipreading system which allows the motion of a speaker and relaxes the restriction on the condition for color and lighting. The proposed system extracts face and lip region from input video sequence captured with a common PC camera and essential visual information in real-time. It recognizes utterance words by using the visual information in real-time. It uses the hue histogram model to extract face and lip region. It uses mean shift algorithm to track the face of a moving speaker. It uses PCA(Principal Component Analysis) to extract the visual information for learning and testing. Also, it uses HMM(Hidden Markov Model) as a recognition algorithm. The experimental results show that our system could get the recognition rate of 90% in case of speaker dependent lipreading and increase the rate of speech recognition up to 40~85% according to the noise level when it is combined with audio speech recognition.

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The Scattering and Absorption Effects of Fluorescence Spectroscopy in a Real Time Optical Biopsy (실시간 광학적 생검에서 형광분광법의 산란과 흡수에 대한 영향)

  • Han, Seunghee;Muller, Markus G.;Kang, Seunghee;Kang, Haejin
    • Progress in Medical Physics
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    • v.12 no.1
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    • pp.79-94
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    • 2001
  • The fluorescence emanating from a biological tissue contains information about scattering, absorption and the intrinsic fluorescence (fluorescence only due to fluorophores). Becaue fluorescence spectra of biological tissue are often significantly affected by the presence of tissue absorbers and scatterers, the measured tissue fluorescence cannot be interpreted as a linear combination of intrinsic fluorescence spectra of different tissue biochemical. We conducted experiments to examine the influence of scattering and absorption on the experimentally measured fluorescence of a turbid medium such as biological tissue. Therefore, we acquired fluorescence and reflectance spectra of tissue phantoms with a wide range of scatterer and absorber concentrations. By applying a photon migration model, which uses the scattering and absorption information contained in reflectance spectra to remove their distortion also present in fluorescence spectra, we extract the intrinsic fluorescence of these tissue models. We achieved excellent agreement between modeled and actual intrinsic fluorescence spectra. The motivation for this research is that intrinsic fluorescence spectra are expected to change with progression of disease in human tissue, due to changes in the tissue biochemical composition. It is not possible to distinguish the two tissue types by using only the measured fluorescence, however clear separation can be achieved with the intrinsic fluorescence in real time optical biopsy.

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