• Explosives and Blasting
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• v.21 no.3
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• pp.17-22
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• 2003

발파작업에서 발생하는 공해로 인한 재산상의 피해나 정신적인 피해를 최소화하기 위하여 대부분의 현장에서 제어발파를 시행하고 있다. 이완식 제어발파는 발파의 규모가 일반발파와 비교하여 작고, 대상 구조물이 근거리에 위치하므로 그 전달특성이 다를 수 있다. 근거리에서 계측된 발파진동의 특징은 고주파이고 진동의 지속시간이 짧다. 본 연구는 국내의 8개 지역에서 계측한 자료를 분석하여 이완식 제어발파의 진동전달 특성에 관하여 국내의 현장에서 시공 전에 진동을 추정할 수 있는 진동전파식을 제안하였다. 또한 제어발파시에 사용하는 폐타이어를 부착한 철재매트에 의한 폭풍압의 저감 효과와 전달특성을 분석하였다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.159-159
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• 1993

개의 관상동맥평활근세포를 이용하여 $K^{＋}$channel openers인 cromakalim과 pinacidil의 이완반응을 관찰하고, 이러한 이완반응의 세포내 기전에 대하여 검토하고자 하였다. Collagenase로 소화시켜 구한 평활근 세포들은 frypan blue 배출 검사 및 전자현미경학적으로 검사시 건전하고 생존해 있었다. 분산평활근세포들은 phenylephrine(PE)의 용량에 의존하여 수축하였고, EC$_{50}$는 2.3$\times$$10^{－12}$M이었다. PE에 의한 수축반응은 $K^{＋}$channel openers인 cromakalim 및 pinacidil의 용량에 의존하여 억제되었고 이때의 EC$_{50}$치는 각각 1,2$\times$$10^{－10}$M 및 6.B$\times$$10^{－10}$M이었다. 비교실험으로서 근절편의 장력을 측정하여 수축을 검정한 실험에서는 cromakalim의 이완반응의 ECEC$_{50}$치는 1.94$\times$$10^{－7}$ M로 근세포실험에 비하여 감수성이 훨씬 약하였다.훨씬 약하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.1834-1836
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• 2015

스트레스는 인체 생리에 영향을 미쳐 과도한 스트레스가 지속되는 경우 신체적 질환으로 이어질 가능서이 크다. 따라서 스트레스 감소의 필요성이 증가하고 있으며 향기요법과 조명을 활용하여 스트레스를 감소시키기 위한 활동이 활발해지고 있다. 본 연구에서는 향기요법과 조명이 스트레스에 미치는 영향에 대한 기존 연구 사례를 조사하여 보편적으로 적용되는 스트레스 이완법에 대하여 고찰하였다. 결과적으로 발향 방법은 연구마다 달랐지만 보편적으로 베르가못(Bergamot) 향을 10분 정도 흡입하였을 때 스트레스 이완효과가 나타남을 확인하였다. 조명의 경우 파랑색, 녹색과 같은 한색 계열의 색상을 3분 정도 투사하는 경우 이완효과를 보이는 것으로 조사되었다.

• Journal of Music and Human Behavior
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• v.7 no.1
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• pp.17-36
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• 2010

The purpose of this study is to investigate the effects of imagery-centered music listening on the physiological and psychological relaxation of women with high-risk pregnancy. A total sample of 15 subjects participated in 11 sessions. The research data was collected only in the first session for each subject. In this experimental study, physiological and psychological relaxation were evaluated by peripheral temperatures and the Visual Analog Scale (VAS), respectively. For the music listening program for imagery experience, 27 pieces of relaxing music were selected and the modified MI technique was used. After interventions, the results showed that peripheral temperatures increased and the VAS scores decreased. Imagery exercises with music listening offered a positive experience to elicit physiological and psychological relaxation in subjects. In conclusion, imagery-centered music listening is an effective modality to facilitate relaxation, stability, and support for women with high-risk pregnancy.

• Journal of the Korean GEO-environmental Society
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• v.15 no.5
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• pp.13-21
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• 2014

This study analyzed the differences in the analysis techniques through a comparative analysis of the various segment's modeling techniques of Shield TBM method and proposed reasonable modeling techniques. Also, this study suggested reasonable estimating methods of load to be applicable in the field through the load analysis and three-dimensional finite element analysis by estimating model of rock mass relaxation load. Estimating method of relaxation area by rock mass rating makes no odds of output in subgrade with high rock mass rating, but so the difference of output is large, that is judged to set conservative design off. In estimating result of rock mass relaxation area by three-dimensional analysis relaxation area of subgrade with low-grade soil was predicted to be positioned at medium-range of many methods, in case of designing segment in subgrade with low-grade soil it needs to actively review estimation of relaxation area through three-dimensional analysis reflecting mechanical tunnel excavation.

• The Korean Journal of Pharmacology
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• v.31 no.1 s.57
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• pp.27-37
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• 1995

In anesthetized rats, we examined the possibility that endothelium-derived relaxing factor (EDRF) or nitric oxide (NO) released in response to cholinergic mechanism may contribute to the reflex autoregulation of cerebral blood flow. Suffusion with mock cerebrospinal fluid (CSF), containing acetylcholine (ACh, $10^{-9}{\sim}10^{-6}M$) evoked concentration-dependent vasodilatation of the resting pial artery (mean, $19.3{\pm}1.7{\mu}m$, n=36), which was significantly inhibited not only by $N{\omega}$-nitro-L-arginine (L-NNA, $10^{-5}M$) but also by methylene blue ($10^{-6}M$) and oxyhemoglobin ($10^{-6}M$). The muscarinic receptors in the endothelium of pial artery implicated in the release of EDRF were considered to be $M_1\;and\;M_3$ subtypes. When suffused with mock CSF containing L-arginine it caused a transient vasodilatation, which was strongly inhibited by LY 83583 ($10^{-5}M$), but not by L-NNA ($10^{-5}M$). Additionally, both ACh- and L-arginine-induced vasodilation were significantly inhibited by glibenclamide, a specific ATP-sensitive $K^+$ channel blocker. On the other hand, changes in pial arterial diameter were plotted as a function of changes in systemic arterial blood pressure. The slopes of regression lines for vasodilation and vasoconstriction were not affected by pretreatment with $10^{-5}M$ L-NNA, but significantly reduced by $3{\times}10^{-6}M$ glibenclamide. Thus it is suggested that the reflex vasodilation of rat pial arteries in response to a transient hypotension is not mediated by EDRF (NO).

• Korean Journal of Veterinary Research
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• v.41 no.3
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• pp.299-304
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• 2001

The effect of the nitric oxide synthase(NOS) inhibitor, $N^{G}$-nitro-L-arginine methyl ester (L-NAME), and the prostanoid synthesis inhibitor, indomethacin, on the vasodilatation produced in response to acetylcholine(Ach) on the isolated rabbit renal artery was examined. The vasodilatory reponses to Ach($10^{-8}-3{\times}10^{-5}M$) were completely absent in thevessel which the endothelium had previous been removed. L-NAME($10^{-4}M$) significantly reduced the vasodilatory reponse to the Ach($10^{-8}-3{\times}10^{-5}M$). When L-arginine ($10^{-3}M$) was also present in the organ bath along with L-NAME($10^{-4}M$), this inhibitory effect of L-NAME ($10^{-4}M$) on the vasodilatory response to Ach ($10^{-8}-3{\times}10^{-5}M$) was significantly attenuated, Indomethacin ($10^{-6}M$) did not significantly affect the vasodilatory responses to Ach ($10^{-8}-3{\times}10^{-5}M$). The inhibition by L-NAME ($10^{-4}M$) and indomethacin ($10^{-6}M$) on vasodilatory response to Ach was significantly greater than the inhibition due to L-NAME ($10^{-4}M$) alone. The present study has established that Ach induce relaxation via and endothelium-dependent mechanism, this relaxation to Ach involves both nitric oxide(NO) and prostanoid in the isolated rabbit renal artery.

• Journal of the Korean Society of Radiology
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• v.10 no.7
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• pp.511-519
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• 2016

Left ventricular diastolic dysfunction is mostly observed in patients with cardiac disease, such as myocardial ischemia or LVH, but linking is usually observed in healthy people without heart disease. Evaluation of left ventricular diastolic failure in normal cardiac output(systolic function) conditions can affect the progress and prognosis of heart failure. The direct relevance to the epicardial adipose tissue metabolism in cardiovascular engine for generating a bioactive moleculer, which leads to dysfunction of the later had a direct effect on myocardial heart. The purpose of this study is to measure the thickness of the epicardial adipose tissue was to study the relevance of the assessment of diastolic dysfunction in systolic function in normal conditions. Results epicardial adipose tissue thickness and diastolic dysfunction was analyzed to have a high correlation in a statistically significant level. In particular, the epicardial adipose tissue thickness measured at the measuring section EAT2 and diastolic function evaluation E' was found to have a high correlation. Thus epicardial adipose tissue thickness variation is believed can be used as a predictor to evaluate the left ventricular diastolic dysfunction.

• Journal of the Korean Geotechnical Society
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• v.30 no.8
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• pp.13-24
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• 2014

A series of trapdoor model tests was systematically performed in order to investigate soil arching. The mobilized soil arching was clearly observed by change of the vertical earth pressure loaded on trapdoor of soil container box. A slow decent of the loading plate at the trapdoor results in loosening zone over the trapdoor and the stress in this loosening zone was transferred to the stationary zone in the vicinity of the trapdoor. In particular, it was observed that the vertical earth pressure rapidly decreased in the loosening zone and increased in the stationary zone at the trapdoor. Both the maximum decreasing rate of the vertical earth pressure in the loosening zone and the increasing rate of the vertical earth pressure in the stationary zone were not influenced by the ground density, but affected by the size of the trapdoor. The loosening zone could be defined by the elliptical configuration, in which the major axis was twice as long as the height of the loosening zone at the center of trapdoor and the minor axis was the same as the width of trapdoor. The height of loosening zone at the center of trapdoor was one and a half times as long as the width of trapdoor loading plate.

• Investigative Magnetic Resonance Imaging
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• v.2 no.1
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• pp.67-72
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• 1998

The mapping of the spin-spin relaxation time T2 in pixel-by-pixel was suggested as a quantitative diagnostic tool in medicine. although the CPMG pulse sequence has been known to be the best pulse sequence for T2 measurement in physics NMR, the supplied pulse sequence by the manufacture of MRI system was able to obtain the maximum of 4 CPMG images. Eight or more images with different echo time TEs are required to construct a reliable T2 map, so that two or more acquisitions were required, which easily took more than 10 minutes. 4-echo CPMG imaging pulse sequence was modified to generate the maximum of 8 MR images with evenly spaced echo time TEs. In human MR imaging, since patients tend to move at least several pixels between the different acquisitions, 8-echo CPMG imaging sequence reduces the acquisition time and may remove any mis-regitration of each pixels signal for the fitting of T2. The resultant T2 maps using the theoretically simulated images and using the MR images of the human brain suggested that 8 echo CPMG sequence with short echo spacing such as 17-20 msec can give the reliable T2 map.