• Journal of Bio-Environment Control
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• v.17 no.1
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• pp.43-50
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• 2008

This study was conducted to investigate the proper supplied conditions of sodium selenate supplied by fertigation to improve functionality of major western vegetables; beet, broccoli, cabbage lettuce, celery, and parsley in highland. In this work, the growth and content of minerals, ascorbic acid, nitrate, and selenium were measured in western vegetables that treated sodium selenate by different concentration, treatment time and treatment frequency. While there was not different in early growth of some western vegetables among different concentration of sodium selenate; 1,2, 5 and $20\;mg{\cdot}L^{-1}$, at 20 days after treatment, the fresh weight was reduced 33% at cabbage lettuce,47% at broccoli, and 74% at parsley compared control in $5\;mg{\cdot}L^{-1}$ treatment. But the fresh weight of beet and celery reduced just 20% and 15% compared control in even $20\;mg{\cdot}L^{-1}$. The ascorbic acid of cabbage lettuce, celery, and beet increased as sodium selenate concentration increased, so that of cabbage lettuce showed 1.2 times compared control in $20\;mg{\cdot}L^{-1}$ treatment and also that of beet and celery increased 10%. But the ascorbic acid of broccoli and parsley was not influenced by treated sodium selenate. As the concentration of sodium selenate increased, the nitrate contents decreased regardless of crops compared control. This reduced effect of nitrate was highest in cabbage lettuce, followed by beet and celery. The mineral contents, such as K, Ca, and Mg, decreased in all crops, as the concentration of sodium selenate increased. The potassium content showed an obvious negative correlationship with the concentrations of sodium selenate regardless of crops, but the magnesium and calcium content did not show significant difference between treatments. The selenium content increased in proportion as increasing sodium selenate concentrations. The broccoli, celery and parsley treated $20\;mg{\cdot}L^{-1}$ sodium selenate showed 24.4 times, 76.4 times, and 560 times higher than control, respectively. When the sodium selenate supplied to some western vegetables in different growth stage, the selenium content increased 1.3 times and 1.4 times higher in early stage than in late stage in cabbage lettuce and broccoli, respectively. However in parsley and celery, the selenium content showed the highest in middle stage. The selenium content increased in proportion as increasing the sodium selenate treatment frequency, but in above 10 times treatment, the increased effect alleviated in parsley, celery, and cabbage lettuce. On the contrary, the selenium content of broccoli increased constantly as treatment frequency increased.

• Journal of Preventive Medicine and Public Health
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• v.29 no.3 s.54
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• pp.439-449
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• 1996

This study was conducted to evaluate the relationship between change in obesity indices and change in serum lipids in adult male workers. Two-hundred-eight adult male workers of an industry in Taegu city were followed-up from 1991 to 1995. Height, weight, circumferences of hip and waist, blood pressure were measured and serum lipids were analysed. Data on life style were obtained using self-administered questionnaires. Mean differences of anthropometric measurements between 1991 and 1995 were as follows: 1.63kg in weight, 3.61cm in waist circumferences, 4.23cm in hip circumferences, $0.52kg/m^2$ in BMI and -0.021 in WHR. Those of lipids were as follows; 15.09mg/dl in total cholesterol, 20.43mg/dl in triglyceride, 9.40mg/dl in HDL-cholesterol, 2.87 in MI - index (p<0.01) and 350mg/dl in LDL-cholesterol. The changed value of BMI and Katsura index were strongly correlated with that of total cholesterol(r=0.174, p<0.05), the changed value of BMI correlated with that of triglyceride(r=0.374, p<0.01) and the changed value of weight correlated with that of MI index(r=-0.173, p<0.05). The changed value of WHR was signifiantly correlated with that of total cholesterol(r=0.162, p<0.05), however, was not significantly correlated with HDL-cholesterol, LDL-cholesterol, triglyceride and MI index. The changed value of weight, BMI and Katsura index were correlated with that of triglyceride (r=0.262, p<0.01; r=0.267, p<0.01; r=0.258, p<0.01) and the changed value of MI index(r=0.143, p<0.05; r=-0.158; r=-0.144, p<0.01), adjusting the pattern of change in life style. The changed values of HDL - cholesterol and MI index between 1991 and 1995 in low WHR group were significantly higher than those in high WHR group(p<0.05, p<0.01), adjusting the baseline value of them. Similar pattern was observed when considering Katsura index. When stratifying by BMI value of 1991, in low BMI group, the changed value of HDL - cholesterol and MI index showed the same pattern as above, however that of triglyceride was statistically higher in obese group than in non obese group(p<0.05). In conclusion BMI might be a better indicator to predict serum lipids change than other obesity indices.

• Development and Reproduction
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• v.12 no.1
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• pp.57-66
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• 2008

Changes in luteinizing hormone (LH), serum testosterone (T), and salivary T levels with age were examined in Korean men. Serum was obtained from 167 Korean men of different ages ($20{\sim}69\;y$), and the serum LH and T levels were measured. Saliva samples were also obtained, and the salivary T level was determined. The LH levels did not change considerably until 40 y of age (20s, $2.5{\pm}1.0$; 30s, $2.7{\pm}1.5$; and 40s, $2.5{\pm}1.8\;mIU/mL$) but increased significantly around 50 y (50s, $3.7{\pm}1.8$ and 60s, $3.1{\pm}1.7\;mIU/mL$). Further, the serum T levels also did not change until 40 y of age (20s, $5.3{\pm}2.6$, 30s, $4.4{\pm}1.4$, 40s, $4.1{\pm}1.5\;ng/mL$) but decreased significantly at 50 y (50s, $3.4{\pm}1.5$; 60s, $2.6{\pm}0.8\;ng/mL$). The salivary T levels also showed small changes until the age of 40 y ($20s{\sim}40s$, $0.11{\pm}0.015\;ng/mL$) but decreased significantly at 50 y ($0.08{\pm}0.03\;ng/mL$). Thus, the relative ratio of salivary T to serum T levels did not change significantly in all the ages examined ($2.4{\pm}0.9%$). Linear regression analysis predicted that the LH levels increased 1.5%/y while the serum and salivary T levels decreased 1%/y and 0.8%/y, respectively. The serum T/LH ratio did not change considerably until the age of 40 y ($20s{\sim}40s$, $2.27{\pm}0.14$) but decreased significantly ($1.2{\pm}1.0$) at 50 y. Age-related changes in the salivary T/LH ratio were very similar to those in the serum T/LH ratio. These results demonstrated that LH and T levels in serum or saliva did not change considerably until 40 y of age; instead, in Korean men, from 50 y of age, the LH level increased, while the T level decreased. This suggests that primary testicular failure that occurred due to aging (approximately 50 y) and caused this phenomenon. The present study also shows that the salivary T level can be an indicator of the free T level in serum although the salivary T level correlates weakly with the total T level in serum (r=0.53). Thus, information regarding salivary T levels may be useful for studying the age-related changes occurring in male testicular physiology.

• Korean Journal of Psychosomatic Medicine
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• v.13 no.2
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• pp.95-101
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• 2005

Objectives : This study was designed to investigate depression, anxiety, alexithymia, stress res ponses in caregivers of patients with attention deficit hyperactivity disorder. Methods : The subjects were 38 attention deficit hyperactivity disorder patients caregivers(38 women, mean age $37.5{\pm}6.5$). Patients were diagnosed with DSM-IV ADHD criteria. Korean version of Beck Depression Inventory(BDI), State and Trait Anxiety Inventory(STAI), Toronto Alexithymia Scale(TAS) and Stress Response Inventory(SRI) were used for assessment. Results 1) The BDI scores of ADHD patients caregiver group were significantly higher than control group$(16.4{\pm}7.1\;vs.\;10.9{\pm}5.5)(p=0.011)$. 7 of the 38 caregivers(18.4%) and none of control group(0%) had BDI scores over 20 points(p=0.021). Calculated relative risk for ADHD in the presence of caregivers' depression was 1.516 overall(95% confidence interval, 1.234-1.862). 2) In ADHD patient's caregiver group, the scores of Stress Response Inventory were significantly higher than control group$(44.2{\pm}20.2\;vs.\;26.5{\pm}16.8)(p=0.006)$. 3) No significant differences were found in the score of STAI, SIAIS, SIAI-T, TAS between caregiver and control group. Conclusion : This study suggest that ADHD patients' caregivers are likely to have more depressive symptoms and higher stress response level than control group. We propose that physicians should consider integrated approaches for caregiver's psychopathology in the management of ADHD.

• Korean Journal of Environmental Agriculture
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• v.25 no.1
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• pp.64-70
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• 2006

This study was conducted to investigate the concentration of fertigation for optimum yield and soil management of tomato cultivation in soils with different Electrical conductivity (EC) level under PE film house. The EC levels of soil were adjusted to 1.4, 3.0 and 5.4 dS/m and fertigation concentrations were supplied with 0.0 (groundwater), 1.0, 2.0 and 3.0 dS/m, respectively. When the concentration of fertigation was supplied over 3.0 dS/m to soil with EC 1.4 dS/m, the concentrations of $NO_3-N,\;avail.-P_2O_5$, and exchangeable K in soil were increased after the experiment. When fertigation concentration was supplied over 2.0 and 1.0 ds/m to soil with EC 3.0 and 5.4 dS/m respectively, the nutrient were also accumulated in the soil. Thus, the optimum concentrations of fertigation for optimum yield and soil management for tomato cultivation were recommended $1.0{\sim}2.0dS/m$, 1.0 dS/m and ground water (0.0 dS/m) to soils with EC 1.4, 3.0 and 5.4 dS/m, respectively. The fruit weight marketability and marketable yield of tomato were not significant among the treatments at 5% level by LSD. The concentrations of T-N, $P_2O_5\;and\;K_2O$ in tomato leaf were increased with increasing of fertigation concentration whereas the concentrations of CaO and MgO decreased with increasing of fertigation concentration.

• Clinical and Experimental Pediatrics
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• v.45 no.6
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• pp.754-763
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• 2002

Purpose : The incidence of type 2 diabetes in children and adolescents has been reported to increase recently. The aim of this study is to investigate the clinical features of type 2 diabetes developing during childhood and adolescent period. Methods : The medical records of 33 patients with type 2 diabetes were reviewed. We analysed clinical manifestations, demographic data, and modes and responses of treatment. Results : Age at diagnosis was $13.4{\pm}1.8$ years. Seventy percent of patients revealed pubertal signs at diagnosis. Half of the patients had BMI more than $25kg/m^2$. Seventy-three percent of patients had family history of type 2 diabetes. Acanthosis nigricans were found in 18% of patients. Nineteen(57.6%) patients were diagnosed incidentally by random urine or blood glucose test without any typical diabetic symptom or sign. The modes of therapy to control hyperglycemia were insulin alone(75.8%), oral hypoglycemic agents alone(9.1%), insulin and oral hypoglycemia agents(9.1%), and only diet with exercise(6%). At the time of investigation, 45.5% of patients were not using insulin. The typical diabetic symptoms at diagnosis were more prevalent in patients who required insulin for more than two years than patients who did not(P<0.05). Conclusion : The development of type 2 diabetes in children and adolescents is possibly related to puberty, obesity, family history, and defects in insulin secretion rather than insulin resistance. Many children and adolescents with type 2 diabetes required insulin initially and some of them could discontinue. More than half of the patients were diagnosed as diabetes without any typical symptom or sign, which might be one of the predictive factors of the prolonged insulin requirement.

• Reproductive and Developmental Biology
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• v.37 no.1
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• pp.23-27
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• 2013

This study was carried out to investigate the influence of artificial insemination (AI) failure in 1,619 Korean native cows at Gangwon East area, Korea. The average AI failure rate was 37.02% in the cows and the highest rate was 40.85% in Yangyang-city. Based on the parity in the cows, the AI failure rate was 49.14% and 29.91% in the first and fifth parity cows, respectively. Whereas cows until fifth parity were decreased in AI failure, cows with sixth or more parity showed an upturning AI failure trends with the increasing of parity number. AI failure rate incidence according to the rump fat thickness measured by ultrasound was 28.9% and 33.4% at 5 mm to 10 mm and over than 15 mm, respectively. There was a positive correlation (0.2186) between AI failure rate of mother and that of their offspring cows. That is, offspring of dams with high AI failure rate showed also higher AI failure than those of dams having lower AI failure rate. In conclusion, these results indicate that the AI failure rate was closely related to the rump fat thickness, parity number, and conception rate of mother cows. In addition, these results might strengthen the basis to improve the reproductive performance in Korean native cows.

• Journal of Korean Society of Environmental Engineers
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• v.22 no.12
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• pp.2197-2204
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• 2000

Lignin is a major component of wastewater generated in the chemical processing of wood. Because it is recalcitrant, it inhibits biological treatment of wastewater of pulp manufacturing, especially high concentration of lignin may inhibit the anaerobic digestion. The objective of this study was to evaluate the toxicity of high molecular hardwood lignin (lignosulfonate, MW $\geq$ 20,000) on aceticlastic methanogens in the batch reactors at different temperatures with different sludge concentrations, using anaerobic serum bottles. The hardwood lignin was found to inhibit anaerobic conversion of acetate to methane and carbon dioxide, shown with a long lag-phase before methanogenesis started. The methanogens assumed not to be able to acclimate to the lignin were found to be acclimated slowly in the batch experiments, finally reaching non-toxic levels in which methane production could start. The hardwood lignin was found not to be bacteriocidal but bacteriostatic to aceticlastic methanogens. Hardwood lignin(lignosulfonate) at 1.3, 2.6, and 3.9%(w/w) inhibited the acetateutilizing methanogens of anaerobic digester sludge by 14.5, 17.8, 21.1 days(in noninhibitory condition it took 10 days) to produce the same amount of methane. The inhibitory effect of lignin was examined at temperature ranges of $30^{\circ}C$ to $50^{\circ}C$. When 2.6% of lignin was contained in wastewater, methane production was highest at $30^{\circ}C$ during initial 8 days. At $4^{\circ}C$, methane production rapidly increased after 12 days of digestion, the value became higher than that at $30^{\circ}C$ after 14 days. However, the methane production was completely inhibited during whole digestion period at $50^{\circ}C$. High ratio of lignin concentration to initial anaerobic sludge concentration gave tolerance to the inhibition. In this experiment, high molecular hardwood lignin was not degraded and decolorized.

• Journal of Sasang Constitutional Medicine
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• v.12 no.1
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• pp.24-36
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• 2000

Purpose : Many believe that the Sasang mentioned in the I Ching and the Sasang of Sasang Medicine (as expounded by Dr. Lee Je-ma in the book Longevity and Life Preservation in Oriental Medicine) refer to different concepts. This is untrue. In order to understand the thought patterns of Dr. Lee Je-ma and his book, it is necessary to first understand the concepts of the I Ching. The I Ching was the most respected text in Dr. Lee Je-ma time, and served as the foundation upon which his medicine stood. The purpose of this research is to understand the concept of Sasang in the I Ching and how it applies to the Sasang medicine. Method : The authors first defined the term Sasang according to the theory of I Ching. It was then discussed in relation to theories of modern science. Inferences were made as to how Sasang corresponds to the terminologies and concepts of modern science. The characteristics of Sasang interpreted through modern science were then applied to the physiology, pathology and pharmacology of Sasang Medicine. Results and Conclusion : 1. The Sasang theory of the I Ching organizes seemingly random and isolated natural phenomena into four distinct groups according to various attributes. The particular characteristics representing each of these four categories are known as Sasang. 2. The Sasang theory of I Ching has a strong correlation to the Theory of Relativity and the Theory of Complementarity, as well as the Digital and Fractal Theories. 3. By applying the Sasang Theory to various fields, the seemingly unrelated principles of physics, chemistry, biology and medicine can be seen as parts of a whole. 4. Sasang Medicine categorizes human morphology, physiology and pharmacology into four categories according to the characteristics defined by the Sasang Theory of the I Ching. 5. Grouping new discoveries of modern physics, chemistry, biology and medicine according to the Sasang Theory will bring to light the intricacies of the Sasang Theory while facilitating the incorporation of modern science into Sasang Medicine.

• Food Science and Preservation
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• v.19 no.1
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• pp.123-130
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• 2012

In this study, 80% ethanolic extracts of tartary and common buckwheats were assessed for their total phenol content, total flavonoids content, antioxidant activity (DPPH, ABTS radical scavenging activity and reducing power), and anti-adipogenic effects. Our results show that total phenol contents of 80% ethanolic extract from tartary and common buckwheats were $17.35{\pm}0.41$ and $8.20{\pm}0.28\;{\mu}g$ GAE/g, respectively. Antioxidant activities of 80% ethanolic extract from tartary buckwheat were significantly higher than that of common buckwheat extract (p<0.05). During adipocyte differentiation, 80% ethanolic extracts of tartary and common buckwheat significantly inhibited lipid accumulation compared to control cells. We further evaluated the effect of buckwheat extracts on the changes of key gene expression associated with 3T3-L1 adipogenesis and ROS production. Tartary buckwheat extract was more suppressed the mRNA expressions ($PPAR{\gamma}$ and aP2) than that of common buckwheat extract. Moreover, tartary buckwheat inhibited the mRNA expression of both NOX4 (NADPH oxidase 4) and G6PDH (glucose-6-phosphate dehydrogenase). These results indicate that anti-adipogenesis effect of tartary buckwheat can be attributed to phenolic compound that may potentially inhibit ROS production.