• Title/Summary/Keyword: 융합율

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Application of Molecular Diagnostics Technology in the Development of a Companion Diagnostics for Malignant Solid Tumors (악성 고형암의 항암제 동반진단 기술에서 분자진단기술의 적용)

  • Kim, Jin-Hee
    • The Journal of the Korea Contents Association
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    • v.19 no.3
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    • pp.365-374
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    • 2019
  • Unlike benign tumors, malignant tumors are capable of metastasis, easy to relapse, poor survival, and low quality of life. In Korea, here is a tendency to treat the tumors collectively according to the General Principles of Cancer Chemotherapy(GPCC) of the Health Insurance Review & Assessment Service (HIRA). But recently, companion diagnostics(CDx) is recommended rather than unilateral medication because biomarker-based molecular diagnostics is possible to predict the drug response of patients before drug treatment. Not only domestic but also overseas Food and Drug Administratio (FDA) recommends the development of the CDx system at the stage of drug development to ensure the responsiveness and safety of medicines. In this study, I focused on the necessity of CDx development direction as well as CDx development status through literature review. Furthermore I also discussed CDx types according to the molecular diagnostic technology such as immunohistochemistry (IHC), polymerase chain reaction (PCR), in situ hybridization (ISH), and next-generation sequencing (NGS) not only in the approved CDx but also in the developing one by US FDA. And I suggested the technology issue of CDx development process such as a selection of molecular diagnostics at the time of release, a clear understanding of the CDx mechanism, and a convergence of drug with CDx development. The necessity of social insurance system also was proposed for CDx development.

Analysis of Fuel Marginal Price for Biomass Power Plant - On the Basis of China Biomass Power Plant - (바이오매스 발전소 연료한계단가 분석 - 중국 바이오매스 발전소를 중심으로 -)

  • Kim, Cheol;Sa, Jae-Hwan;Kim, YunSoung;Jeon, Eui-Chan
    • Journal of Climate Change Research
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    • v.1 no.3
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    • pp.219-226
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    • 2010
  • This study is analyzed the financial feasibility of biomass power plant in China in terms of fuel marginal price of biomass power plant. The range of fuel price is 150~300 RMB and IRR(Internal Rate of Return), NPV(Net Present Value), DSCR(Debt Service Coverage Ratio) and operation time are analyzed by 10 RMB from 150 RMB. The sensitivity of IRR went down by 1.35 on average. The sensibility of NPV showed big difference by 20% on 260 RMB and 270 RMB. In addition, DSCR of loan is at 1.0 at raw cost of 242 RMB and at lower than 1.0 when the raw cost over 242 RMB. It means that the pay-off of principal and interest of the loan is expected to be difficult in that case. The operation time of power plant should be 88% against standard operation time to maintain over 1.0 of DSCR. Therefore, the factors affecting the cost of raw material to build the power plant and to operate it should be prioritized.

Database Analysis for Estimating Design Parameters of Medium to Large-Diameter TBM (중대단면 TBM 설계 사양 예측을 위한 DB분석)

  • Choi, Soon-Wook;Park, Byungkwan;Chang, Soo-Ho;Kang, Tae-Ho;Lee, Chulho
    • Tunnel and Underground Space
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    • v.28 no.6
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    • pp.513-527
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    • 2018
  • The Tunnel Boring Machine(TBM) is relatively insufficient to cope with unpredicted changes in ground conditions as compared with Conventional Tunnelling Methods. Therefore, it is very important to predict the TBM performance at the design stage and estimate the advance rate for the calculation of the construction period. In this study, we added data to 211 TBM databases constructed in the previous study and analyzed the correlation between TBM outer diameter, maximum thrust, maximum cutterhead torque, cutterhead driving power and RPM, which are the main design and manufacturing specifications of TBM. As a result of the analysis from results obtained in the previous studies, it was confirmed that TBM outer diameter is very effective and important in estimating maximum thrust, maximum cutterhead torque, and cutterhead driving power of the TBM. As a result of comparing the regression equations derived from other TBM databases outside the country and the regression equation obtained from the present study results, the maximum thrust showed a similar tendency to each other, but the maximum torque estimated from the regression equation of this study was higher than that of other countries in the case of the large scale TBM.

A Convergence Study on Removal Effects of Dental Plaque from General and Chewing Toothbrush (일반 칫솔과 씹는 칫솔의 치면세균막 제거 효과 융합연구)

  • Kim, Song-I;Song, Eun-Young;Lee, Yu-Na;Jeong, Yong-Mi;Hwang, Ui-Sun;Kang, Kyung-hee
    • Journal of Digital Convergence
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    • v.16 no.12
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    • pp.505-510
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    • 2018
  • This study aimed to compare the elimination effect of dental plaque between general toothbrushes and chewing toothbrushes, so as to investigate whether the chewing toothbrushes have the practicality as the alternatives of general toothbrushes and their utilities in the real life. The study subjects were 30 healthy adults in their 20s who maintained the good dental condition over 16 teeth without systemic diseases, and the decline rates of dental plaque index after usages of general and chewing toothbrushes were calculated. Upon the comparisons of dental plaque decline rates before and after the usages of general and chewing toothbrushes, PHI index was declined from 7.02 to 1.91 in case of the general toothbrush demonstrating dental plaque decline by 72.79%, while it was declined from 6.72 to 4.08 in the chewing toothbrush demonstrating decline by 39.29%. Currently, a variety of dental care items are available in the Korean market, hence, various studies are required on the dental care items so as for the people to properly choose the items.

Feasibility Assessment of Spectral Band Adjustment Factor of KOMPSAT-3 for Agriculture Remote Sensing (농업관측을 위한 KOMPSAT-3 위성의 Spectral Band Adjustment Factor 적용성 평가)

  • Ahn, Ho-yong;Kim, Kye-young;Lee, Kyung-do;Park, Chan-won;So, Kyu-ho;Na, Sang-il
    • Korean Journal of Remote Sensing
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    • v.34 no.6_3
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    • pp.1369-1382
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    • 2018
  • As the number of multispectral satellites increases, it is expected that it will be possible to acquire and use images for periodically. However, there is a problem of data discrepancy due to different overpass time, period and spatial resolution. In particular, the difference in band bandwidths became different reflectance even for images taken at the same time and affect uncertainty in the analysis of vegetation activity such as vegetation index. The purpose of this study is to estimate the band adjustment factor according to the difference of bandwidth with other multispectral satellites for the application of KOMPSAT-3 satellite in agriculture field. The Spectral band adjustment factor (SBAF) were calculated using the hyperspectral satellite images acquired in the desert area. As a result of applying SBAF to the main crop area, the vegetation index showed a high agreement rate of relative percentage difference within 3% except for the Hapcheon area where the zenith angle was 25. For the estimation of SBAF, this study used only one set of images, which did not consider season and solar zenith angle of SBAF variation. Therefore, long-term analysis is necessary to solve SBAF uncertainty in the future.

An analysis of storage and runoff reduction characteristics using planter box in architectural LID system (건축형 LID 시스템에서 Planter Box를 활용한 저류 및 유출저감 특성 분석)

  • Kim, Byung Sung;Kim, Jae Moon;Baek, Jong Seok;Shin, Hyun Suk
    • Journal of Korea Water Resources Association
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    • v.52 no.3
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    • pp.219-226
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    • 2019
  • Recently, research about Low-Impact Development (LID) techniques has been expanded due to problems with the effects of climate change and urbanization that have been increasing. LID technology is used to control flood damage environmentally to reduce runoff and is reduce runoff on city also restore into previous water circulation system from present developed city. However, studies about quantitative data of LID techniques are insufficient. Therefore in this study, the Curve Number (CN) was calculated with the Planter Box, which is storage type LID technology to conduct the water circulation (infiltration, runoff, overflow) analysis. Rainfall intensity scenario (60.4 mm/hr, 83.1 mm/hr, 97.4 mm/hr, 108.2 mm/hr) about water circulation analysis of Planter Box is selected on the basis of probable rainfall intensity table. According to the experimental results, the storage rate of rainwater in Building Planter Box and Street Planter Box was 43.5% to 52.9% and 33.4% to 39%, respectively. In addition, CN value is estimated to 83 at the Planter box and the runoff reduction effect by applying Horton's infiltration capacity curve showed on 51% to 98%.

The Effect of Nursing Managers' Leadership Type perceived by Nurses on the Job Performance and Turnover Intention through A Latent Class Analysis (잠재계층분석에 의한 간호사가 지각하는 간호관리자의 리더십유형이 업무수행능력과 이직의도에 미치는 영향)

  • Kang, Ji Yeon;Kim, Hye Sook
    • The Journal of the Convergence on Culture Technology
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    • v.5 no.1
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    • pp.193-203
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    • 2019
  • The study participants are nurses who work at three general hospitals in M City, who used structured questionnaires to list 214 people from July 17 to August 7, 2017. Analysis of the collected data was carried out using SPSS WIN 21.0. and M plus 7.00 to analyze latent classes depending on the type of nursing managers' leadership. This study showed that the type of nursing managers' leadership has in analyzing latent classes influences nurses' job performance and turnover intention. Because there is a strong influence on the job performance and the turnover intention so that nurses can be highly aware of transformation-transaction-emotion leadership, the managers of the nursing organization need to foster effective leadership. Training programs are needed to improve nurses' job performance through transformational, transactional, and emotional leadership, and to foster nursing manager's leadership skills to better reflect the turnover intention.

Development on Identification Algorithm of Risk Situation around Construction Vehicle using YOLO-v3 (YOLO-v3을 활용한 건설 장비 주변 위험 상황 인지 알고리즘 개발)

  • Shim, Seungbo;Choi, Sang-Il
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.622-629
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    • 2019
  • Recently, the government is taking new approaches to change the fact that the accident rate and accident death rate of the construction industry account for a high percentage of the whole industry. Especially, it is investing heavily in the development of construction technology that is fused with ICT technology in line with the current trend of the 4th Industrial Revolution. In order to cope with this situation, this paper proposed a concept to recognize and share the work situation information between the construction machine driver and the surrounding worker to enhance the safety in the place where construction machines are operated. In order to realize the part of the concept, we applied image processing technology using camera based on artificial intelligence to earth-moving work. Especially, we implemented an algorithm that can recognize the surrounding worker's circumstance and identify the risk situation through the experiment using the compaction equipment. and image processing algorithm based on YOLO-v3. This algorithm processes 15.06 frames per second in video and can recognize danger situation around construction machine with accuracy of 90.48%. We will contribute to the prevention of safety accidents at the construction site by utilizing this technology in the future.

A Study on the Use of Mobile Payment Service by Korean Youth (우리나라 청소년들의 모바일 간편 결제서비스 이용에 관한 연구)

  • Moon, Jae-Young
    • The Journal of the Korea Contents Association
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    • v.20 no.12
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    • pp.492-497
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    • 2020
  • Today, banks around the world are making great efforts to adapt to the rapidly changing internal and external environment changes caused by the development of IT technology and to gain a competitive advantage in the market. In particular, in line with the rapid growth of smartphone usage, financial services are also provided in a variety of ways using Fintech, and one of the fastest growing areas is mobile simple payment. Mobile payment service is a financial service that pays the purchase price using a portable mobile device. As fintech, a convergence of financial services and information technology, it is recently used not only in financial services, but also in various industries. It is used in all fields where payment functions such as distribution are available. In the case of mobile cards, it shows that the usage rate of people in their 20s and 30s is increasing very much, so it can be said that the use of mobile payment services will continue to increase in the coming future. We know that simple payments are being used. However, it can be said that the research on the use of mobile payment services by these teenagers is somewhat incomplete. Therefore, this study investigated what factors are important for Korean teenagers to use mobile payment services. As a result, among the five hypotheses presented in this study, all hypotheses were adopted except for , which states that cash usage habits have no effect on innovation.

Evaluation of NOx Reduction Performance by Photocatalytic (TiO2) Coating of Cement Mortar Mixed with Zeolite and Activate Hwangtoh (제올라이트와 활성 황토를 혼입한 시멘트 모르타르의 광촉매(TiO2) 코팅에 따른 NOx 저감성능평가)

  • Park, Jang-Hyun;Kim, Hyeok-Jung
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.8 no.4
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    • pp.483-489
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    • 2020
  • Particulate matter is divided into PM10 (particle diameter of 10 ㎛ or less) and PM2.5 (particle diameter of 2.5 ㎛ or less), which are approximately 1/5 of the thickness of the hair. Due to its effect on the human body, lung disease, arteriosclerosis and heart It is known as a carcinogen that causes various diseases such as diseases. It is known that the main cause of such fine dust is nitrogen dioxide (NOx), which is emitted from automobiles in about 57.3% of urban roadsides. Therefore, in this study, as part of the development of functional construction materials to reduce NOx generated from road transport pollutants, comparative evaluation of NOx reduction performance was conducted according to the replacement rate of cement mortar in which cement was replaced with a porous material. In addition, the NOx reduction performance of cement mortar according to the photocatalyst application method and the number of applications was compared an d evaluated. As a result of the experiment, when activated ocher was substituted by 30%, it showed a reduction effect of about 32.7%, showing the best reduction performance.