• Journal of Chest Surgery
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• v.29 no.5
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• pp.524-529
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• 1996

200 cases of pulmonary tuberculosis patients treated by surgical resection were anlized Bronchial resection margin was examined by microscopic study to detect submucosal tuberculosis granuloma. 6 cases of bronchopleural fistula that occurred after resection were also asnalized to fond any relation with submucosal granuloma. Among 200 cases, 19 cases (9.5%) showed submucosal granu- loma. Of the 19 cases, 2 cases (10.5%) developed ea ly and late bronchopleural fistula On the con- trary, only 2.2% developed in granuloma negative cases. Granuloma positive cases were mote fre- quently seen in preoperative sputum positive cases and showed incidence of residual pleural dead space resection.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1991.06a
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• pp.38-38
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• 1991

콜레스테롤 육아종은 콜레스테롤 결정이 주위조직에 이물질로 작용하여 육아성 반응 및 골파괴 반응을 유발시키는 질환으로 병리조직학적으로 많은 콜레스테롤 결정이 거대세포를 가진 만성적인 염증성 침윤속에 나타나는것을 특징으로 한다. 이 병변은 아주 드물지만 특징적인 방사선적소견, 병리조직학적 소견과 임상양상으로 쉽게 진단이 된다. 두부에서는 다양한 위치에서 발견되는데 특히 함기화가 잘 된 측두골, 유양동, 고실강에서 많이 보이며 전두골, 상악골, 협골, 인상측두골 및 후두개와에서도 보고되고 있으나 부비동에 발생하는것은 특히 드물다. 부비동에서 발생한 콜레스테롤 육아종의 발생기전은 환기장애설, 배출장애설 및 출혈설 등으로 보고되고 있다. 저자들은 최근 복시와 측두통을 호소하는 50세 여자환자에서 접형동에 발생한 콜레스테롤 육아종이 우측 상안와열 (superior orbital fissure)과 경사대(clivus)를 파괴하며 전교조 (Prepontine cistern)로 확장된 1례를 경험하였기에 임상 증세, 특징적인 전산화단층 및 핵자기공명소견과 병리조직학적인 소견을 문헌 고찰과 함께 보고하는 바이다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.13.4-13
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• 1981

The Wegener's granulomatosis is a rare disease of unknown etiology characterized by ulcerative, necrotic lesion of the upper respiratory tract, progressive pulmonary and renal involvement, and death in a period six months. Relentless progression with rapid death resulting from renal involvement and failure is the usual outcome, but limited forms with confinement to the upper respiratory tract are seen. The authors, recently, have observed a case of Wegener's granulomatosis which was confirmed as pathologically, so present this case with a brief review of the literature.

• Pediatric Infection and Vaccine
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• v.21 no.1
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• pp.53-58
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• 2014

Chronic granulomatous disease (CGD) is an inherited immunodeficient disease characterized by recurrent infections and granuloma formation. Granulomatous obstruction of esophagus is one of the rare complications of CGD. The use of steroids and antimicrobials for esophageal obstruction by granuloma in CGD patients has been controversial due to the possibility of concomitant inapparent infection. We report a case of esophageal obstruction in an 8-year-old CGD patient showing the poor response to antibiotics therapy. However, dramatic improvement of symptoms and radiologic findings of esophageal obstruction were achieved after steroid therapy. One month after discontinuation of steroid, esophageal obstruction recurred and the patient was re-treated with steroid. After that time, he experienced one more recurrence of esophageal obstruction. This symptom subsided after antibiotics therapy without steroid and he has been followed up to the present without further relapse.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1981.05a
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• pp.9.1-10
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• 1981

The clinical study of 183 cases of laryngeal mass was observed and 88 cases of vocal nodule and polyp which is confirmed histopathologically, were clinically classified into 30 cases of vocal nodule, 48 cases of localized vocal polyp, 10 cases of diffuse vocal polyp, and the following results of microscopic examination were obtained. I. The clinical study of laryngeal mass 1. Among total cases of 183, vocal nodule is 82(45%) vocal polyp 53(29%) postintubation granuloma 3(1%) laryngeal papilloma 18(10%) tuberculosis 2(1%) cancer 25(14%). 2. The sex ratio of male to female is 3:4 in vocal nodule, 1:1 in vocal polyp, 1:2 in postintubation granuloma, 3:2 in laryngeal papilloma, 11:1 in cancer. 3. The age distribution is third-fourth decade in vocal nodule, fourth-fifth decade in vocal polyp, third decade in postintubation granuloma, second and fifth decade in laryngeal tuberculosis, sixth decade in laryngeal cancer. 4. The distribution of symptoms is 5 month. -1 year in vocal nodule and polyp, less than 1 year in laryngeal papilloma and postintubation granuloma, 1 year-3 year in laryngeal tuberculosis and cancer. 5. The location of the lesion is between the anterior 1/3 and middle 1/3 in vocal nodule and polyp and papilloma, middle 1/3 and posterior 1/3 in postintubation granuloma, and is diffusely spread on the entire vocal cord in laryngeal tuberculosis and cancer. 6. The side of the lesion is bilateral in vocal nodule and papilloma and the ratio of right to left is 5:3 in vocal polyp, 2:1 in postintubation granuloma. 7. The size is 1~2mm(67%) in vocal nodule, 3~5mm(42%) in vocal polyp, 6~10mm (67%) in postintubation granuloma, 1~2mm (39%) in papilloma, more than 10mm in tuberculosis and cancer. 8. Among the symptoms, the hoarseness is in more than 90% of disease entity, the sore-throat in tuberculosis and cancer, the dyspnea in postintubation granuloma and papilloma and tuberculosis and cancer. 9. In the past history, certain relationship with smoking is noted in cancer (40%) and tuberculosis(50%) and the history of frequent attack of URI is in papilloma(33%). 10. In occupation, certain statistical significance was not noted. II. The histopathological study of vocal nodule and polyp. 1. Most polyps and nodules were covered with stratified squamous epithelium, but focal hyperkeratosis, parakeratosis, acanthosis and atrophy were rather frequently observed. Hyperkeratosis and acanthosis was most frequently seen.

• The Journal of the Korean bone and joint tumor society
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• v.13 no.2
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• pp.119-123
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• 2007

Giant cell reparative granuloma (GCRG) is an uncommon benign lesion that is most commonly found in the mandible and maxialla, and is a very rare condition in finger. We report an unusual case of GCRG arising in the index finger of a 21-year-old man. Histology was characteristic of giant cell reparative granuloma.

• The Journal of the Korean bone and joint tumor society
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• v.12 no.2
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• pp.171-175
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• 2006

The involvement in the spine of eosinophilic granuloma is not common. Especially, involvement of cervical spine and posterior neural arch is quite rare. In addition, radiographic findings including magnetic resonance images of eosinophilic granuloma are manifested as vertebral body collapse, loss of pedicle and paravertebral soft mass formation; it must be differentiated with other conditions, such as malignant bone tumor, metastatic cancer or tuberculous spondylitis. We experienced three cases of eosinophilic granuloma involving posterior neural arch of C4, C7, and body of C4 respectively, which were performed surgical treatment and achieved complete healing. We report these cases with review of literatures.

• Journal of Gastric Cancer
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• v.6 no.4
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• pp.291-294
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• 2006

F-18 FDG-PET/CT could be used to evaluate the surveillance of recurrent stomach cancer, but some cases reported as false-positives. The authors found an activated charcoal granuloma from intraperitoneal chemotherapy by using a curative resection and mitomycin C for stomach cancer. A mass behind the right colon that showed on CT 6 months after an operation in a 46-year-old male patient had no progression in size, but 36 months after the operation, an increase was seen on F-18 FDG-PET/CT, and a metastatic tumor was suspected. The tumor was resected by an explorative laparotomy and was diagnosed as being an activated charcoal granuloma based on the histologic finding. Based on this case, we should be reminded of the possibility of a false-positive on analysis of F-18 FDG-PET/CT caused by an activated charcoal granuloma in a patient who has intraperitoneal chemotherapy.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.13 no.2
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• pp.177-184
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• 1991

A giant cell granuloma and a cementifying fibroma occurring in the same lesion of right mandibular body in a 10 year old boy is presented with a 12 month follow up without recurrence or any other complications after operation. The relatively small lesion of cementifying fibroma was well delineated from the larger lesion of central giant cell granuloma, and as their origins are different each other(odontogenic or connective tissue origin), we have considered that both lesions had developed independently. Clinically, the evidencesa of aggressiveness of giant cell granuloma were also found, that is, large size, earlier age of 10, root resorption of lower right 1st annd 2nd molars and cortical perforation. With curettage and electric cauterization, we have treated both lesions satisfactorily.

• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.2
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• pp.310-315
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• 2001

The soft tissue tumors that occur commonly in newborn infants include palatal and gingival cyst of the newborn, congenital epulis, hemangioma, teratoma, pyogenic granuloma, and irritation fibroma. Such soft tissue tumors in the alveolar ridge of newborns are usually treated by surgical excision. If untreated, they can cause airway obstruction and breathing difficulty due to aspiration. They also cause discomfort during oral feeding. If nasal feeding is tried, since vomitting is impossible, there is a risk of aspiration pneumonia. In this case, a newborn infant visited our hospital with soft tissue tumor as chief complaint, and the infant was treated by surgical excision. It appeared to be similar to pyogenic granuloma and irritation fibroma upon histologic exam. However, it was different from those diseases since multinucleated giant cells were observed and it was congenital. The pathologic process of this neoplasm is not clear. This case is reported, since it is difficult to classify it as a specific disease.