• Proceedings of the Korea Society of Environmental Biology Conference
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• 2002.11a
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• pp.154-162
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• 2002

인간이나 환경에 해로운 영향을 주는 지속성 유기오염물질의 독성을 동물플랑크톤 중 요각류를 대상으로 실험하였다. 실험에 사용된 요각류는 장목만에서 주로 가을에 많은 출현을 보인 Acartia erythraea와 늦가을부터 그 다음해 봄까지 우점하는 A. omorli였다. 지속성 유기오염물에 대한 요각류의 독성을 평가하기 위해 3가지의 실험을 실시하였다. 광양만에서 주로 나타나는 5가지 PAHs에 대한 A. omorli 48h-LC50을 구하였고, 온도에 따른 Benzo(a)pyrene과 TBT의 독성의 변화를 Brine shrimp(Artemia)를 이용해 실험하였으며, PAHs 중에서 독성이 강한 Benso(a)Pyrene에 노출된 먹이를 섭취한 Acartia erythraea와 A. omorli의 egg Production, hatching rate, fecal Pellet의 변화를 측정하였다. A. omorli의 48h-LC50으로 조사된 결과 Fluoranthene과 Benzo(a)pyrene의 독성이 강하게 나타난다. 온도실험에서는 동일한 유해물질을 가지고 실험을 하더라도 온도의 변화에 따라 급격한 독성의 차이가 나타날 수 있고, 유해물질간에도 온도에 따라서 나타나는 독성에 대한 특성이 다르게 나타났다. Benzo(a)Pyrene에 노출된 먹이는 요각류의 egg Production, hatching rate, fecal Pellet에 영향을 미치고 있으며, 특히 농도와 실험시간에 따른 부정적 영향들을 보였다.

• Journal of Haehwa Medicine
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• v.17 no.1
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• pp.53-57
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• 2008

These day, herbal drugs have been widely used in all over the world, as primary therapeutics or supplements for treating various diseases. Herbal drugs are generally regarded as non-toxic due to their natural origin and long history traditionally used without serious adverse reactions. However, plenty warnings have been reported, particularly about the potential hepatotoxicity of herbal products. This report would be helpful for understanding theory of toxicology and prevent from herbal drug-derived hepatotoxicity in Oriental medicinal field.

• Science of Emotion and Sensibility
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• v.8 no.2
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• pp.155-160
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• 2005

The aim of this study was to examine the effects of aqua-acupuncture a mixture of bos taurus domesticus and selenarctos thiberanus, and bos taurus domesticus, selenarctos thiberanus and Moschus moschiferus on an animal model of arthritic pain. Under halothane anesthesia, arthritic pain was induced by the injection of $2\%$ carrageenan into the left knee joint cavity of male Sprague-Dawley rats. The responses of afferents to a movement cycle were recorded before and after aqua-acupuncture. The aqua-acupuncture at acupoints reduced neural responses to noxious movement stimulation. Aqua-acupuncture at Zusanli inhibited neural responses of articular afferents to noxious stimulation more than at Hegu. These results indicate that aqua-acupuncture of a mixture of bos taurus domesticus and selenarctos thiberanus, and bos taurus domesticus, selenarctos thiberanus and Moschus moschiferusmay provide a potent strategy in relieving arthritic pain.

• Journal of the Korea Institute of Building Construction
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• v.19 no.1
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• pp.31-38
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• 2019

In this study, amine derivatives and ion exchange resins were selected to actively control penetration ions ($SO{_4}^{2-}$, $Cl^-$) as the element technology of repair materials for concrete structures in drainage environments. Ions ($SO{_4}^{2-}$, $Cl^-$) adsorption performance and corrosion resistance of calcium hydroxide solution with amine derivative and ion exchange resin were confirmed by ion chromatography and potentiostat analysis. As a result of the experiment, it was confirmed that the amine derivative is excellent in the adsorption of chlorine ion and the ion exchange resin is excellent in the adsorption of sulfate ion. It has been confirmed that corrosion resistance can be increased by proper combination of two materials in the calcium hydroxide solution containing sulfate ion and chloride ion simulating sewage environment.

• 건강소식
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• v.30 no.2 s.327
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• pp.6-9
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• 2006

최근 들어 알레르기 질환이 급증하고 있다. 국내 알레르기 환자 수는 6백만 명 이상이며 서구화된 생활환경, 공해, 각종 화학물질 사용의 증가로 인해 환자는 계속 증가 추세이다. 현재 추정되는 환자수 만도 전 인구의 15~20%선, 우리 나라 성인 중 약 10%, 어린이는 약 20%에서 나타나고 있는 것으로 알려져 있다. 대표적인 알레르기 질환은 꽃가루에 의한 화분증과 집먼지 진드기, 동물의 털 등이 주원인인 알레르기성 비염.결막염.천식.피부염 등이 있다. 그러나 알레르기 질환은 주위에서 흔히 접하면서도 일반인들에게 막연히 알려져 있고, 단지 완치가 힘들어 난치병 정도로만 인식되어 있다. 알레르기 질환 보통 대부분의 사람에게 있어서는 아무런 문제도 일으키지 않는 물질이 어떤 사람에게만 두드러기, 비염, 천식 등 이상과민반응을 일으키는 것을 말한다. 알레르기도 우리 몸 속에서 일어나는 면역반응의 한 종류지만 몸에 유해한 반응을 말하며 요즘 들어서는 과민성이란 의미로 사용된다.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.120.1-120.1
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• 2014

고온 plasma는 전자, 이온, 중성입자로 구성된 이온화된 기체로 국소열평형 상태의 구성입자가 수천도에서 수만도에 이르는 큰열용량을 갖는 불꽃형태를 이루고있다. 따라서 고온 plasma는 고온, 고열로 대상물질을 용융 또는 기화시켜 물질의 물리적상태를 변화시키는 열원역활을 하거나, 높은반응성을 갖는 입자들에 의한 화학반응을 촉진하는 반응촉매로 작용하여 고기능성 부품소재, 에너지 환경, 원자력, 항공우주,유가금속 재활용등의 분야에서 핵심적인 역활을 하고 있슴니다. 본 발표에서는 연구소에서 지금까지 국책과제로 수행되었던 고온 plasma을 유해폐기물(병원, 유독 액상폐기물, 군화공폐기물, 중금속 함유 폐기물, 폐 plastic 가스화 등)처리에 관한 전반적인기술을 소개하고져함.

• Environmental Analysis Health and Toxicology
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• v.19 no.3
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• pp.295-305
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• 2004

본 연구에서는 유전자 재조합 발광 박테리아를 이용하여 농약에 대한 박테리아의 스트레스 반응과 세포 독성을 분석하였다. 15종류의 농약에 대하여 유전자 손상, 생물막 손상, 산화적 손상 및 단백질 손상을 측정할 수 있는 발광 박테리아와 독성 유무로 인한 세포 독성을 측정할 수 있는 발광 박테리아, 5종을 이용하여 스트레스 반응을 분류하고 세포 독성 정토를 분석하였다. 그 결과, 농약의 화학적 구조가 박테리아의 스트레스 반응에 영향을 미치며, 산화과정이 진행 됨에 따라 독성의 작용 기작이 변하는 것을 확인 할 수 있었다. 이와 같은, 유전자 재조합 발광 박테리아를 이용한 생물체내의 독성 메커니즘에 대한 분석은 생태계 유해물질들에 의한 독성을 분석하고 예상하기 위해 적용될 수 있을 것이다.

• International Journal of Highway Engineering
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• v.13 no.3
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• pp.1-6
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• 2011

The possibility of ASR(alkali-silica reaction) for coarse aggregates had known to be low up to recently in Korea. But the distress of ASR was identified and reported by ASTM C 1260 test. The purpose of this paper was to identify the effect of environmental conditions on length expansion of mortar-bar by alkali-silica reaction with KS F 2546 and ASTM C 1260 test. The results of this study were as following; The result of KS F 2546 test for five kinds of aggregates shows that all of them are non-reactive. But that of ASTM C 1260 test shows that all of aggregates except Andesite-2 are over possible reactive because of environmental condition such as external alkali ion by 1N NaOH, high temperature and humidity. The result of variety of NaOH concentration on ASTM C 1260 using Siltstone indicates that length expansion rate increases highly as NaOH concentration increases. And, comparison results of KS F 2546 for Siltstone with that of 0.00N NaOH experiment indicates that length expansion rate increases as temperature and humidity increases.

• Korean Journal of Environmental Agriculture
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• v.17 no.1
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• pp.76-83
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• 1998

The most remarkable aspect in the hormesis law is that dose of harmful agents can produce effect that are diametrically opposite to the effect found with high doses of the same agent. Minute quantities of a harmful agent bring about very small change in the organism and control mechanisms appear to subjugate normal processes to place the organism in a state of albert and repair. The stimulated organism in more responsive to changes in environmental factors than it did before being alerted. Routine functions, including repair and defense, have priority for available energy and matetial. The alerted organism utilizes nutrients more efficiently, grows faster, shows improved defense, and lives longer. Accelerated germination, sprouting, growth, development, blooming and ripening, and increased crop yield and resistance to disease are found in plants. Another concept supported by the data in that low doses of ionizing radiation provide increased resistance to subsequent high doses of radiation. The hormesis varies with subject plant, variety, state of seed, environmental and cultural conditions, physiologic function measured, dose rate and total exposure. The results of hormesis are less consistently found, probably due to the great number of uncontrolled variables in the experiments. The general dosage for radiation homlesis in about 100 (10 to 1,000) times ambient or 100 (10 to 1,000) times less than a definitely harmful dose, but these must be modified to the occasion. Although little is known about most mechanisms of homzesis reaction, overcompensation of repair mechanism is offered as one mechanism.

• Pediatric Infection and Vaccine
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• v.18 no.1
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• pp.68-79
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• 2011

Purpose : This post-marketing surveillance study (NCT00750360) assessed the safety and reactogenicity of an inactivated, trivalent split-virion influenza vaccine licensed for use in the Korea since 2002. Methods : Eight hundred and eighty three subjects aged 6 months received a single dose of the ${\geq}$ vaccine; an additional dose was administered to those aged <9 years and unprimed with an influenza vaccine. Four hundred and eleven subjects used diary cards to record safety information; this report presents data from these subjects. Incidence of solicited local, general and unsolicited adverse events (4-days and 21-days post-vaccination follow-up periods, respectively) were recorded. Serious adverse events (SAEs) were recorded throughout the study period. Results : Injection site pain (subjects aged <6 years: 12.6% of subjects, ${\geq}$6 years: 34.7%), fever (<6 years: 1.3%) and myalgia (${\geq}$6 years: 13.9%) were the most frequently recorded solicited local and general adverse events. Grade 3 solicited adverse events were reported by ${\leq}$4.0% subjects. No vaccine-related SAEs were recorded (KFDA criteria). Conclusion : Considering the vaccine's well-established immunogenicity and its favourable safety and reactogenicity profile across all age groups and its high coverage rate in Korea, it may be recommended as a candidate to facilitate annual seasonal influenza vaccination for all ages as part of the Korean National Immunization Program.