• Title/Summary/Keyword: 유사작용제 인체시험

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Facile Fabrication of Chemical Vapor Samplers with Various Adsorbents for Man-in-Simulant Test(MIST) (Man-in-Simulant Test(MIST) 실험을 위한 다양한 흡착제의 화학증기 흡착용 샘플러 제작)

  • Jung, Hyunsook;Lee, Kyoo Won;Choi, Geun Seob;Park, Myungkyu;Lee, Haewan
    • Journal of the Korea Institute of Military Science and Technology
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    • v.17 no.1
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    • pp.129-134
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    • 2014
  • We have developed a cost-effective and facile method to manufacture a pouch-type chemical vapor sampler. Originally, the sampler was developed by U. S. Army Natick Soldier Research, Development, and Engineering Center(NSRDEC) to determine the protective capability of individual protective ensembles or Man-in-Simulant Test (MIST). They used a selectively permeable high density polyethylene(HDPE) as front membrane and aluminum/ Nylon barrier film as an impermeable back sheet in order to mimic the actual adsorption process that occurs when the skin is exposed to chemical weapons. However, it costs over twenty dollars per sampler and the minimum of quantity is 2500 per order. In addition, it is inconvenient to employ a variety of adsorbents into the sampler, which could prevent MIST researchers to do various tests for development of MIST methodologies. Here, we report the simple method to manufacture the sampler in a laboratory scale. All the materials we used are easily obtainable and inexpensive. In addition, all the procedures we perform are generally known. We used methyl salicylate(MeS) vapor to be adsorbed into the sampler and employed several different adsorbents to evaluate the performance of samplers. The results obtained by home-made samplers and commercially avaliable one showed no significant differences. Also, MeS vapor was selectively adsorbed into the sampler depending on adsorbents. We conclude that home-made samplers are capable of collecting any kind of chemical vapor for a variety of purposes.

Development of Chemical Vapor Sampler for Man-in-Simulant Test(MIST) (화생방 개인보호체계 시험평가용 화학증기 흡착 샘플러의 개발)

  • Jung, Hyunsook;Lee, Kyoo Won;Kah, Dongha;Jung, Heesoo;Ko, Chung Ah;Choi, Geun Seob;Park, Hyen Bae;Lee, Hae Wan
    • Journal of the Korea Institute of Military Science and Technology
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    • v.18 no.4
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    • pp.387-394
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    • 2015
  • We have recently developed a cost-effective and pouch-type chemical vapor sampler which consists of a selectively permeable high density polyethylene(HDPE) membrane, aluminum/nylon barrier film, and adsorbents. Since the sampler mimics the actual adsorption process that occurs when the skin is exposed to chemical vapors, it can be applied to man-in-simulant test(MIST) to determine the protective capability of individual protective ensembles for chemical warfare agents. In this study, we describe the manufacturing process of samplers and results for performance testing on MIST. Methyl salicylate(MeS) is used to simulate chemical agent vapor and the vapor sampler was used to monitor chemical concentration of MeS inside the protective suit system while worn. Values of protection factors(PF) were also analyzed to provide an indication of the protection level of the suit system evaluate by MIST. The results obtained by home-made samplers(ADD samplers) and commercially avaliable ones(Natick samplers) showed no significant differences.