• Journal of the Korean Society for information Management
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• v.39 no.1
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• pp.91-117
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• 2022

The number of depressed patients in Korea and around the world is rapidly increasing every year. However, most of the mentally ill patients are not aware that they are suffering from the disease, so adequate treatment is not being performed. If depressive symptoms are neglected, it can lead to suicide, anxiety, and other psychological problems. Therefore, early detection and treatment of depression are very important in improving mental health. To improve this problem, this study presented a deep learning-based depression tendency model using Korean social media text. After collecting data from Naver KonwledgeiN, Naver Blog, Hidoc, and Twitter, DSM-5 major depressive disorder diagnosis criteria were used to classify and annotate classes according to the number of depressive symptoms. Afterwards, TF-IDF analysis and simultaneous word analysis were performed to examine the characteristics of each class of the corpus constructed. In addition, word embedding, dictionary-based sentiment analysis, and LDA topic modeling were performed to generate a depression tendency classification model using various text features. Through this, the embedded text, sentiment score, and topic number for each document were calculated and used as text features. As a result, it was confirmed that the highest accuracy rate of 83.28% was achieved when the depression tendency was classified based on the KorBERT algorithm by combining both the emotional score and the topic of the document with the embedded text. This study establishes a classification model for Korean depression trends with improved performance using various text features, and detects potential depressive patients early among Korean online community users, enabling rapid treatment and prevention, thereby enabling the mental health of Korean society. It is significant in that it can help in promotion.

• Journal of Korean Medical classics
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• v.19 no.2 s.33
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• pp.11-29
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• 2006

${\ulcorner}$동의수세보원(東醫壽世保元)${\lrcorner}$소음인편(少陰人篇), 유신수열표열병화위수한리한병양대부분조성(由賢受熱表熱病和胃受寒畵寒病兩大部分組成). 신수열표열병(賢受熱表熱病), 분위울광증(分爲鬱狂證), 망양증(亡陽證), 태양병궐음증등삼개병증(太陽病厥陰證等三個病證). 상한론적하초축혈증시사기재하조적혈증(傷寒論的下焦血證是邪氣在下蕉魚的血證), 용저당탕(用抵當湯), 도인승기탕등파열해열지제치료(桃仁承氣湯等破血解熱之劑治療). 단동무인위상한하초축혈증위울축방광증(但東武認爲傷寒下蕉蓄血證爲鬱蓄醫謗胱證) 기병기시신국양기피사소거(其病機是賢局陽氣被邪所拒), 불능상소어비국(不能上疏於脾局), 울축방광(鬱蓄膀胱). 고동무장양기울축적병증시(故東武將陽氣鬱蓄的縮的病證視), 위울광증(爲鬱狂證), 장양기누설적한출시위망양증(將陽氣漏泄的汗出視寫亡陽證). 동무장태양상풍무한증(東武將太陽傷風無汗證), 하조축혈증(下蕉蓄血證), 귀속우울광초증(歸屬于鬱狂初證), 장열입혈실증(將熱入血室證), 양명병위가가실증(陽明病胃家實證), 귀속우울광중증(歸屬于鬱狂中證), 장양명병조열광언증(將陽明病湖熱狂言證), 귀속우울광말증(歸屬手驚狂末證), 장태양상풍한출증(將太陽傷風出證), 귀속우망양초증(歸屬于亡陽初證), 장양명병(將陽明病), 불오한(不惡寒) 반오열(反惡熱) 한자출증(汗自出證), 귀속우망양중증(歸屬手亡陽中證), 장양명병(將陽明病), 발열한다증(發熱汗多證), 귀속우망양말증(歸屬手亡陽末證). 타인위소음인음병당유복만자리(他認爲少陰人陰病當有腹題滿自利), 시병등증상(時病等症狀). 초기약무복통자리적증상이견궐음증(初起若無複痛自利的症狀而見厥歐陰證), 인위시정사상지일구이경기쇠갈소치(認爲是正邪相持日久而正氣衰竭所致).

• Korean Journal of Psychosomatic Medicine
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• v.15 no.1
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• pp.14-21
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• 2007

Premenstural dysphoric disorder(PMDD) imposing 4-5% of women is possibly caused by an enhanced responsiveness to the changes of sex steroid hormones and the decrease of serotonin, melatonin and GABA. The common clinical features between PMDD and depression, seasonal affective disorder, panic disorder and anorexia nervosa suggest a relatedness between PMDD and each of them. The diagnostic criteria of DSM-IV-Tr for PMDD requires psychological symptoms, that commonly include irritability, anger, depression, mood swing, affect lability, tension, anxiety, fatigue and food craving. As of today, the best pharmacological treatment for PMDD is the selective serotonin reuptake inhibiter, and leuprolide, danazol, estradiol, spironolactone and bromocriptine are possible alternatives. Nonpharmacological treatments for patients with mild to moderate symptom severity are diet, exercise, light therapy, psychotherapy and keeping a diary.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.7
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• pp.237-248
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• 2017

The purpose of this study was to evaluate the effects of mindfulness-based cognitive therapy(MBCT) on chronic depressed patients. MBCT has shown great effects for curing depression and proving it can also prevent the relapse of depression. In recent years in Korea, there has been ongoing MBCT research, but has not been applied as a group program to chronic depressed patients. After reviewing the research and organizing data of MBCT treatment therapy mechanism, results found that the chronic depressed patients showed positive effects from the MBCT program. This study involved 8 patients aged 40-55, measuring the level of mindfulness(FFMQ), decentering, rumination, and depression symptoms before and after treatment from the MBCT program. The results indicate that there was a significant increase in FFMQ(mean change score=1.37, p<0.05) and decentering(mean change score=1.00, p<0.05), while there was a significant decrease in rumination(mean change score=-0.67, p<0.05) and BDI(mean change score=-9.5, p<0.05). These results have been continued during the 6 months. The MBCT program has prevented the relapse of depression, acting as a maintenance therapy.

• Journal of Veterinary Clinics
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• v.16 no.2
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• pp.482-485
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• 1999

45일된 암컷 English Coca Spaniel(0.65kg, 증례 1)과 60일 된 암컷 진돗개(2.05 kg, 증례 2)가 항문폐쇄증으로 내원하였다. 증례 1은 생후 5일부터 만성적인 설사를 보였으며, 내원 7일 전에 이유시켜 상업용 건사료로 바꾸었다. 내원 당시의 임상증상은 복부팽창, 식욕부진, 항문폐쇄 그리고 질 주위에 오줌과 변으로 오염되어 있었다. 증례 2는 내원 당시 우울증, 복부팽만, 항문폐쇄 등의 임상증상을 보였고 질 주위에 수양성 변으로 오염되어 있었다. 증례 1과 2에서 직장 조영술을 실시해서 직장과 질에 누공이 형성되고, 결장이 팽만되어 있음을 확인하고 수술을 실시하여 누공을 폐쇄하고 항문 형성술을 실시하였다. 증례 1은 수술직후 항문에 변이 불연속적으로 배출되었고, 2달후에는 정상적인 항문괄약근의 운동을 관찰할 수 있었다. 증례 2는 술후 4일에 식욕부진과 원기소실로 폐사하였다.

• Korean Journal of Clinical Pharmacy
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• v.20 no.3
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• pp.229-234
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• 2010

섬유근통 증후군은 만성 전신 통증을 나타내며 피곤, 두통, 우울증, 수면장애 등을 동반하는 질환이다. 주로 30-50대의 여성에게서 많이 나타나며 미국에서 2-4%, 한국에서 2%의 발병률을 보이고 있다. 정확한 원인과 기전이 밝혀져 있지 않아서 진단과 치료에 많은 논란과 어려움이 있다. 현재는 증상치료에 목표를 두고 삼환계항우울약을 많이 사용하고 있으나 심각한 부작용의 문제가 있다. 이러한 문제 때문에 최근에는 selective serotonin reuptake inhibitor (SSRI) 또는 serotonin-norepinephrine reuptake inhibitor (SNRI)를 빈번히 사용하고 있다. 본 연구는 SNRI의 하나인 milnacipran의 섬유근통 증후군 치료에 대한 효능 및 안정성을 알아보기 위해, MEDLINE에 등재된 논문을 기한없이 milnacipran과 fibromyalgia로 검색하여 무작위 배정 및 이중맹검 임상연구자료들을 선별하였다. 선별된 6개의 임상연구 결과, milnacipran를 사용했을 때 일관된 효능성과 안정성이 관찰되었고 섬유근통증후군 치료와 그에 수반되는 여러증상에 효과적인 것으로 나타났다.

• Journal of Preventive Medicine and Public Health
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• v.25 no.1 s.37
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• pp.1-12
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• 1992

To assess the pattern of psychiatric symptoms and to evaluate the relationship between exposure related variables(duration of work and urinary hippuric acid concenturation) and psychiatric symptoms in organic solvent exposed workers, case control study of forty-two solvent exposed workers and ninethy-six non-exposed workers was conducted. The general health questionnaire 28(GHQ28) was administered to evaluate psychiatric symptoms and urinary hippuric acid concenturations was measured to estimate the present status of solvent exposure in exposed group and to estimate normal level in non-exposed group. The mean concenturation of urinary hippuric acid was significantly higher in exposed group (2.953g/creatinine g) than non-exposed group(0.395g/creatinine g) (P<0.01). The total positive rates of symptoms were significantly higher in exposed group(28.2%) than non-exposed group(17.5%)(P<0.05). The positive rates of symptoms for four sub-scales of GHQ28 in exposed group were in the order of somatic symptoms, anxiety, social dysfunction, depression and in the order of social dysfunction, anxiety, depression, somatic symptoms in non -exposed group. The positive rates of symptoms for somatic symptoms and anxiety were significantly higher in exposed group than non-exposed group (P<0.05) and the proportion of workers with six or more positive symptoms(dysthymic states) in exposed group were significantly higher than non-exposed group (P<0.01). After the effect of age, sex, level of income, level of education, and duration of work were controlled, the total score of GHQ28 was still significantly different between exposed and non-exposed group(P<0.01). In multipile logistic regression analysis on the dysthymic state, the odds ratio of level of income was statictically significant in both group. The odds ratios of exposure related variables such as duration of work and hippuric acid concenturations were not statistically significant but there was a tendency that exposure related variables had an affect on dysthymic state in exposed group. In future, continuous evaluation of psychiatric symptoms on organic solvent exposed workers and studies to detect the factors that affect on psychiatric symptoms are required.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.2
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• pp.129-135
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• 2017

Objectives : Little is known about the influence of urinary incontinence and depression on individual's QOL(Quality of life). We aimed to clarify how the interaction between urinary incontinence and depression influences one's QOL. Methods : A total of 1262 patients were enrolled in this study from April, 2011 to July, 2011. We estimated the severity of depressive symptoms and QOL, using SGDS-K, EQ-5D. We also investigated the morbidity of urinary incontinence for each patient in person or by questionnaire. Comparisons of QOL between groups with or without depression, with or without urinary incontinence were established using t-test, ANOVA and Scheffe's post hoc analysis. The interaction between urinary incontinence and depression was analyzed by each domain of QOL, using multiple regression analysis. Results : Patients with depression and urinary incontinence showed significantly higher EQ-5D scores on every domain of QOL than other patients, which means significantly lower QOL. Patients with depression, no urinary incontinence reported lower QOL, especially in the domain of 'usual activity', 'anxiety' and 'visual analogue scale(VAS)', whereas those with urinary incontinence, no depression showed lower QOL in 'motility', 'usual activities' and 'pain' domain. Statistically significant interaction effects of two diseases were observed in the domain of 'VAS', 'self care' and 'anxiety'. Conclusions : Comorbidity of urinary incontinence and depression showed significantly lower QOL of patients, compared with urinary incontinence or depression respectively, which implies additive interaction effects of the two diseases. Optimal diagnosis and treatment of depression should be emphasized for patients with urinary incontinence.

• Korean Journal of Psychosomatic Medicine
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• v.27 no.2
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• pp.138-146
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• 2019

Objectives : This study examined the association between depression and survival time in terminal cancer patients admitted to the palliative care unit. Emotional problems are important for terminal cancer patients in the palliative care unit, and evaluation of patients' depression plays an important role in treatment planning. Methods : From October 2015 to August 2018, we conducted a retrospective study of 291 terminal cancer patients admitted to a palliative care unit at a university hospital and evaluated depression with PHQ-9 at admission. Of the 291 patients, 146 (50.2%) completed PHQ-9 but 145 (49.8%) were not evaluated due to loss of consciousness or rejection. Results : 4-week survival rate in the Kaplan-Meier survival analysis were 45.4% in the non-depressed group (PHQ-9<10) and 18.7% in the depressed group (PHQ-9≥10). According to the severity of depression, in the Cox proportional hazard model, the risk of mortality in moderate, moderately sever and severe group was 2.778, 1.882 and 3.423 times higher than minimal group, respectively. Conclusions : Of the patients with terminal cancer who were admitted to the palliative care unit, the survival time was shorter in the depressed group than in the non-depressed group. Further research is needed to determine if treatment of depression increase the survival in terminal cancer patients.

• Therapeutic Science for Rehabilitation
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• v.8 no.4
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• pp.19-31
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• 2019

Objective : The purpose of this study was to examine differences of psychological symptoms for mothers of infants with autism spectrum disorder(ASD) according to the level of parenting stress. Methods : The subjects were seventy-two mothers of infants with ASD(aged 22 months to 71 months) completed Korean Parenting Stress Index (K-PSI) and Minnesota Multiphasic Personality Inventory(MMPI-2). The data was analyzed using SPSS 23.0 program. Results : First, total and parent domain of parenting stress were positively correlated with several clinical scales of MMPI-2. However, there was no significant association between the child domain of parenting stress and clinical scale MMPI-2. Second, as a result of verified the difference of psychological symptoms according to level of total and parent domain of parenting stress, high-risks group was significantly higher scores in several clinical scales of MMPI-2 relative to those in normal range group. However, regarding the association between the child domain of parenting stress and psychological symptoms, there was no significant difference in psychological symptoms between high-risks group and normal range group. Conclusions : The results of this study have implications for verified the difference of psychological symptoms according to level of parenting stress among mothers of infants with ASD.