• Title/Summary/Keyword: 용해작용

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In vivo Biological Function of a Fibrinolytic Enzyme after Oral Adminstration (혈전용해효소의 경구투여에 의한 생체 내 작용)

  • Lee, Young-Hoon;Lee, Sung-Ho;Park, Ki-Hoon;Choi, Young-Ju;Lee, Sang-Won;Kim, Cheol-Ho;Cho, Soo-Jeong;Gal, Sang-Wan
    • KSBB Journal
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    • v.21 no.6 s.101
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    • pp.433-438
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    • 2006
  • A fibrinolytic enzyme gene (BCF-1) was subcloned to the pEB vector which is high expression vector in the Bacillus host. The enzyme was purified by using FPLC after ammonium sulfate precipitation. The enzyme was oral-administrated to the rat and checked the bleeding time, blood clotting time and fibrinolytic effect of the serum. In the bleeding time retardation test, it was longer about 1.7 fold in the feeding rat than without feeding. The serum of rat feeded with the enzyme had the fibrinolytic activity from 1 hour to 3 hours after oral-administration. After 3 hours from feeding, the fibrinolytic activity was decreased gradually. Also blood clotting time after bleeding was longer than that of control rat. The enzyme could be detected at band of 30,000 Da in the blood by western blotting. The enzyme was not harmful to the all internal organs of the rats. Taken together, the enzyme originated from B. subtilis BB-1 can be a candidate to develop the drug for thrombosis, arteriosclerosis and myocardial infarction.

Particle Dissolution Effects on Soluble Geo-Mixtures (용해성 지반혼합재의 입자 용해 영향)

  • Tran, M. Khoa;Cho, Se-Hyun;Byun, Yong-Hoon;Shin, Ho-Sung;Lee, Jong-Sub
    • Journal of the Korean GEO-environmental Society
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    • v.12 no.12
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    • pp.5-12
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    • 2011
  • Macro- and micro-behaviors of soluble granular media during dissolution process is investigated by numerical analysis. Soluble media are represented by assemblies of non-soluble particles and soluble particles with the different soluble particles contents. Dissolutions of particles are implemented by reducing sizes of soluble particles. The numerical simulations results exhibit that the vertical displacements increase to certain times and become constant while the porosities still increase until no soluble particles are present. However, the porosities and vertical displacements increase with the increase of soluble particles content. The microscopic views show that the fabrics of media change during dissolution process until the certain times, the higher soluble particles contents, and the larger change in fabric.

DISSOLUTION RATES OF POWDERED ENAMEL TREATED WITH FLUORIDE (불소가 법랑질 용해도에 미치는 영향)

  • Choi, Keun-Bae;Park, Jae-Ho;Choi, Boo-Byung;Kim, Chul-We;Chung, Tai-Young
    • The Journal of the Korean dental association
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    • v.9 no.3
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    • pp.109-113
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    • 1971
  • 본 실험은 한국인 분말법랑질(120~200mesh)을 각 농도의 불소용액, 즉 NaF와 SnF₂용액에 일정시간 작용시킨후 각각의 pH범위내의 acetate buffer용액에 대한 용해도를 관찰하여 얻은 결과는 다음과 가다. 1. 실험한 모든 pH범위내에서 불소를 처리하지 않은 버랑질은 불소를 처리한 법랑질보다 용해도가 크다. 2. NaF농도가 증가하면 할수록 용해도는 감소된다. 3. SnF₂의 용해에 관한 억제효과는 모든 pH범위에서 NaF보다 현저하다.

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Diagenetic history of the Mungok Formation near Machari area, Yongweol, Kangwondo, based on Textural, Isotopic, and Chemical Analyses (강원도 영월군 마차리 부근에 분포하는 오오도비스기 문곡층의 속성역사)

  • Woo Kyung Sik;Choi Seung Jin
    • The Korean Journal of Petroleum Geology
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    • v.1 no.1 s.1
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    • pp.1-13
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    • 1993
  • The diagenetic history of the carbonate rocks of the Mungok Formation near Machari area, Kangwondo, was investigated based on textural, isotopic, and chemical data. Paragenetic relationship among diagenetic minerals, coupled with their distinct geochemical contents, shows that the Mungok Formation have undergone several stages of diagenetic events: 1) shallow marine, 2) meteoric, 3) shallow to intermediate burial, and 4) deep burial diagenesis. Shallow marine diagenesis includes fibrous calcite cementation, micritization, and framboidal pyritization, and meteoric diagenesis involved dissolution and recrystallization of unstable allochems (both aragonite and HMC), syntaxial overgrowth on echinoderm fragments, and equant calcite cementation. During shallow to intermediate burial, idiotopic dolomite and chert formed, and xenotopic dolomitization took place before stylolitization of the rocks. After the rocks were deeply buried, saddle dolomitization, second stage of silicification, and dedolomitization occurred.

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Theoretical Approach of the Quartz Dissolution Rate under Various Temperature, pH and Applied Stress Conditions (다양한 온도, pH, 압력 조건하에서의 석영용해속도에 대한 이론적 접근)

  • Choi, Junghae
    • Economic and Environmental Geology
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    • v.50 no.6
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    • pp.509-515
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    • 2017
  • Quartz is the most abundant mineral in the Earth's continental crust. Therefore, understanding of quartz dissolution and precipitation is very important to know about weathering processes and interactions between rocks and water in hydrothermal and metamorphic environments. This paper presents a basic review on the research about quartz dissolution mechanism under various physico-chemical conditions. We rearranged the relationship between each physico-chemical factor and dissolution mechanism from the results of previous researchers in this paper. From this result, we understood that quartz dissolution and precipitation are affected by each factor such as temperature, pH, and applied stress conditions at contact point. In particular, we recognized that the high pH and temperature conditions have different anion concentrations on mineral's surface. As a result, high pH and temperature conditions have a better effect than applied stress condition to the quartz dissolution mechanism.

Hydrogeochemistry of Groundwater Occurring in Complex Geological Environment of Yeongdong Area, Chungbuk, Korea (충북 영동군 복합 지질지역에서 산출되는 지하수의 수리지화학적 특성)

  • Moon, Sang-Ho
    • Economic and Environmental Geology
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    • v.50 no.6
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    • pp.445-466
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    • 2017
  • Yeongdong area is located in the contact zone between central southeastern Ogcheon belt and Yeongnam massif, in which Cretaceous Yeongdong basin exists. Therefore, the study area has complex geological environment of various geological age and rock types such as Precambrian metamorphic rocks, age-unknown Ogcheon Supergroup, Paleozoic/Mesozoic sedimentary rocks, Mesozoic igneous rocks and Quaternary alluvial deposits. This study focuses on the link between the various geology and water type, and discussed the source of some major ions and their related water-rock interaction. For this study, the field parameters and ion concentrations for twenty alluvial/weathered and eighty bedrock aquifer wells were used. Statistical analysis indicates that there was no significant differences in groundwater quality between wet and dry seasons. Although various types were observed due to complex geology, 80 to 84 % of samples showed $Ca-HCO_3$ water type. Some wells placed in alluvial/weathered aquifers of Precambrian metamorphic and Jurassic granitic terrains showed somewhat elevated $NO_3$ and Cl concentrations. $Mg-HCO_3$ typed waters prevailed in Cretaceous Yeongdong sedimentary rocks. The deeper wells placed in bedrock aquifers showed complicated water types varying from $Ca-HCO_3$ through $Ca-Cl/SO_4/NO_3$ to $Na-HCO_3$ and Na-Cl type. Groundwater samples with $Na-HCO_3$ or Na-Cl types are generally high in F concentrations, indicating more influences of water-rock interaction within mineralized/hydrothermal alteration zone by Cretaceous porphyry or granites. This study revealed that many deep-seated aquifer had been contaminated by $NO_3$, especially prominent in Jurassic granites area. Based on molar ratios of $HCO_3/Ca$, $HCO_3/Na$, Na/Si, it can be inferred that Ca and $HCO_3$ components of most groundwater in alluvial/weathered aquifer wells were definitely related with dissolution of calcite. On the other hand, Ca and $HCO_3$ in bedrock aquifer seem to be due to dissolution of feldspar besides calcite. However, these molar ratios require other mechanism except simple weathering process causing feldspar to be broken into kaolinite. The origin of $HCO_3$ of some groundwater occurring in Cretaceous Yeongdong sedimentary rock area seems to be from dissolution of dolomite($MgCO_3$) or strontianite($SrCO_3$) as well.

Effect of Surfactant Molecules on the Aqueous Solubility of two PAHs (새로운 계면활성제들에 의한 두 PAH의 수중 용해도 증가)

  • 이진희;박재우
    • Journal of Korea Soil Environment Society
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    • v.5 no.1
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    • pp.65-73
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    • 2000
  • Surfactants have been extensively considered for decontamination of the subsurface polluted with hydrophobic organic compounds. In order to investigate the effect of molecular structures on the solubilization of hydrophobic organic compounds, solubility enhancement of two PAHs in solutions of three different surfactants-conventional, dianionic, and gemini. The batch experimental results showed that the gemini was the most effective and the dianionic was the least, indicating that organic carbon content of the surfactants was the major factor which determines the sorption capacity of surfactant aggregates in water, unlike some of the previous reports.

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A New Solubility Parameter for Retention Behavior in Liquid Chromatography (액체크로마토그래피에서 머무름거동에 대한 새로운 용해도파라미터)

  • Dae Sub Oh;Sun Haing Lee;Soo Han Kim;Sang Tae Kim
    • Journal of the Korean Chemical Society
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    • v.32 no.5
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    • pp.458-463
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    • 1988
  • The solubility parameter theory for retention behaviors of phenols in a reversed phase liquid chromatography can be applied to limited ranges of the aqueous solvent system. The many examples of the exception to this theory were found to show no agreement with the retention behavior of phenols. Therefore, a new solute-solvent interaction parameter, ${\delta}_{im}$ is added to the Schoenmakers equation of the solubility parameter theory in LC to approach the equation to the real one. The new solute-solvent interaction pararneter, ${\delta}_{im}$ depends on the kinds of solvent, the solvent composition and the structure of solutes. The parameter, ${\delta}_{im}$ has the linear relationship with the solubility parameter of mobile phase, ${\delta}_{im}$. The prediction of retention behavior by this modified equation turns out to be greater than the previous one.

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A Study on the Interrelationship with Limestone and Limestone - Cave (석회암과 석회동굴의 상관성 연구)

  • 홍시환
    • Journal of the Speleological Society of Korea
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    • no.48
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    • pp.9-16
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    • 1996
  • 석회동굴은 유구한 지구 표면 지층의 역사를 되새겨 주는 석회암 층에서 형성되는 지하동굴이다. 바다 속에서 퇴적되어 형성된 석회암 층이 융기 작용으로 지표면에 상승되어 이른 바 석회암 지표 층을 이루고 있는 곳에서는 빗물에 의한 화학작용으로 땅 표면에서 카르스트 윤회과정의 갖가지 지형지물이 발달되는데, 이 때에 지하에 스며든 지하수의 물리 작용으로 곧 지하수류가 흘러 지나간 공동이 생기게 되고, 나아가서는 낙반 및 확장 등으로 지하동굴이 확장되는데, 2차적인 지하수 침투작용으로 석회질 용해수에 의한 2차 생성물이 형성되어 이른 바 화려한 석회동굴이 이루어진다. 그 석회암의 화학 성분 여하에 따라, 그리고 지하수의 지하 투수량에 따라 석회동굴의 양상은 달리 나타나게 된다.

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Visualization and Quantification of Dissolution of Dense Nonaqueous Phase Liquid Entrapped in Porous Media (다공성 매체내 유기용매(DNAPL)의 용해현상 시각화 및 정량화 연구)

  • Ju, Byung-Kyu;Jeong, Seung-Woo
    • Journal of the Korea Organic Resources Recycling Association
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    • v.16 no.1
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    • pp.46-52
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    • 2008
  • Oils and chlorinated solvents leaking to the subsurface are entrapped in the soil pore and these are called as nonaqueous phase liquids (NAPL). NAPL entrapped in porous media acts as a continuous source for surface and ground water contamination. This study visualized dissolution of trichloroethylene (TCE) entrapped in porous media and quantified the velocity of TCE dissolution using an image analysis technique. As the water velocity increased, the level of dissolution increased. The results imply that a TCE contaminated region having a high infiltration rate and groundwater velocity may result in severe groundwater contamination. Microscopic images of TCE entrapped in porous media showed that TCE present in the preferential flow paths was easily dissoluted into the water phase. However, TCE present in the stagnant flow region was visualized for long time. The results imply that TCE would be still present in the soil if TCE is detected in goundwater.

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