• Korean Journal of Plant Resources
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• v.33 no.5
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• pp.501-515
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• 2020

This study is attempted to prepare criteria to determine target species for conservation, through analyzing vascular flora and medicinal resources plants of Mt. Daedeok and Geumdae-bong in Gangwon Province, Korea. Flora Surveys were conducted 14 times from April, 2017 to October, 2019. Total 428 taxa with 83 families, 245 genera, 356 species, 5 subspecies, 46 varieties and 21 forms were distributed in Mt. Daedeok and Geumdae-bong. Korean endemic species were composed of 19 species. Total 36 taxa of Korean rare plants species were identified including 5 taxa in the degree of CR, 2 taxa in the degree of EN, 12 taxa in the degree of VU, 14 taxa in the degree of LC and 3 taxa in the degree of DD. The naturalized plants were 5 families, 10 genera, 10 species, totaling 10 taxa and medicinal resources plants were 239 taxa with 73 families, 185 genera, 239 species, 30 varieties 4 forms, 4 subspecies. The Urbanization Index (UI) was 2.5% and the Naturalized Index (NI) was 1.9%.

• Korean Journal of Plant Resources
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• v.31 no.2
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• pp.149-161
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• 2018

This study was carried out to investigate the flora of Deokjeongsan Mt. (Ganghwa-gun) from March to October 2016. The vascular plants identified during the 8 round field surveys were a to total of 484 taxa: 107 families, 305 genera, 423 species, 8 subspecies, 48 varieties, 4 forms and 1 hybrid. The plant formation of Deokjeongsan Mt. is the deciduous broad-leaved and conifer mixed forest which is the common one in the middle part of Korean peninsula. All most mountain covered with young secondary forest which is mainly composed of Pinus and Quercus. The plant species diversity largest families were Asteraceae (62 taxa, 12.7%), Poaceae (48 taxa, 9.9%), Cyperaceae (27 taxa, 5.6%), Fabaceae (23 taxa, 4.7%), and Lamiaceae (21 taxa, 4.3%). The four taxa of Korean endemic plants such as Clematis brachyura Maxim., Salix koriyanagi Kimura ex Goerz, Carex brevispicula G. H. Nam & G. Y. Chung, and Hemerocallis hakuunensis Nakai were collected. The vascular plants on the red list according to IUCN evaluation basis were found to be five taxa: Near Threatened (NT) species of Senecio argunensis Turcz., Least Concern (LC) species Pseudoraphis ukishiba Nakai, and Not Evaluate (NE) species of Thladiantha dubia Bunge, Cirsium lineare (Thunb.) Sch. Bip., and Scorzonera austriaca ssp. glabra Lipsch. & Krasch. ex Lipsch., respectively. The floristic regional indicator plants found in this area were 26 taxa comprising one taxa of degree V, two taxa of degree IV, four taxa of degree III, eight taxa of degree II, and 11 taxa of degree I. In addition, the alien plants were identified as 46 taxa and the percentage of naturalized index (NI) was 9.5%, and urbanization index (UI) was 14.3%, respectively.

• Korean Journal of Plant Resources
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• v.19 no.4
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• pp.447-458
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• 2006

The resource plants at the Manduksan and Mireukbong was listed 550 taxa: 107 families, 339 genera, 481 species, 1 subspecies, 65 varieties and 3 forms. Among 550 taxa listed was confirmed 323 taxa of edible plants (58.7%), 384 taxa of medicinal plants (69.8%), 267 taxa of ornamental plants (48.5%) and 268 taxa of the others (48.7%). Based on the list of the rare plants by the Forest Research Institute, 4 taxa were recorded in the studied areas; Lilium distichum (Preservation priority order: No. 159), Tricyrtis dilatata (No. 97), Aristolochia contorta (No. 151), Prunus yedoensis (No. 110) and based on the list of Korean endemic plants, 11 taxa were recorded; Cephalotaxus koreana, Carex okamotoi, Lilium amabile, Populus tomentiglandulosa, Salix purpurea var. japonica, Pseudostellaria multiflora, Prunus yedoensis, Forsythia koreana, Paulownia coreana, Weigela subsessilis, Aster koraiensis. Specific plant species by floral region were total 30 taxa; Prunus yedoensis in class V, Wistaria floribunda in class IV, 3 taxa (Spiraea salicifolia, Acer palmatum, Asperula lasiantha) in class III, 3 taxa (Potentilla dickinsii, Viola tokubuchiana var. takedana, Caryopteris incana) in class II, 22 taxa (Pinus koraiensis, Hosta capitata, Chloranthus japonicus, Salix glandulosa, Juglans mandshurica, etc.) in class I. This site needs urgent countermeasures, because there have increased many man-made damages like planting exotic plants, picking wild plants and soil compaction induced by human trampling.

• Korean Journal of Psychosomatic Medicine
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• v.23 no.2
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• pp.129-135
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• 2015

Objectives : In children and adolescents, the prevalence of overweight has increased in the last 20 years. little research is available on the prevalence of obesity in children with autism spectrum disorders(ASD). The purpose of our study was to determine the prevalence of overweight among a clinical population of children diagnosed with autism spectrum disorders(ASD). Methods : Retrospective chart review of children ages 3-18 years seen between 2012 and 2015 at a Konyang University hospital psychiatric clinic. Diagnostic, medical, and demographic information was extracted from the charts. Body mass index(BMI) was calculated from measures of height and weight recorded in the child's chart. The Center for Disease Control's BMI growth reference was used to determine an age and gender-specific BMI z-score for the children. Results : In our study, children with ASD compared to non ASD group had significantly higher BMI percentiles (p=0.032). The prevalence of overweight($BMI{\geq}85th$ to 95th percentiles) and obesity($BMI{\geq}95th$ percentiles) was 35% and 19% respectively in children with ASD and without ASD. Conclusions : Despite noted limitations, our data suggest that overweight and obesity in children with ASD are more prevalent than without ASD. Longitudinal and further study is needed to examine the factors associated with obesity in this population.

• Journal of the Korean Society of Radiology
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• v.12 no.7
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• pp.869-877
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• 2018

This study analyzed the current status of MRI (frequency, amount of treatment) based on the history of application of the MRI health insurance benefit standard and health insurance claim data. MRI examinations began as a health insurance benefit in 2005. In 2005, the indications were restricted for some diseases, but coverage for benefits in 2010, 2013, 2016, and 2018 was expanded. In 2021, the Ministry of Health and Welfare decided to apply health insurance for all MRI examinations. From 2010 to 2017, the number of MRI examinations increased by 86.7% in 2017 compared to 2010, and the amount of treatment increased by 53.5%. According to general characteristics, the number of MRI examinations was higher in women than in men. By age, the number of examinations was the highest among ages 70-79. Outpatient examinations were more frequent than inpatient examinations, and the number of examinations in the tertiary hospitals was the highest among the types of hospitals. The number of brain MRI examinations was the highest in each exam site. In December 2013, the standard of MRI was expanded for heart disease and Crohn's disease, the number of cardiac MRI and abdominal MRI examinations increased in 2014 compared to 2013. However, the number of examinations is small and not associate with the disease, it would be difficult to say that it affected the increase in the total number of MRI examinations. To assess health insurance sustainability and policy effectiveness, monitoring will be necessary.

• Korean Journal of Environment and Ecology
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• v.35 no.1
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• pp.1-23
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• 2021

This study conducted a survey on flora at Mt. susdolbon(508m), Mt. seongjubong (625.3m), and Mt. sulibong(596.2m), located in Yanggu-gun, Gangwon-do. A total of 403 taxa, including 6 forms, 43 varieties, 4 subspecies, 350 species, 255 genera, and 84 families, were surveyed in the three mountain areas. 18 taxa from 5 families of ferns, 3 taxa from 1 family of gymnosperms, and the dicotyledonous plants as 302 taxa from 69 families of the dicotyledonous plants were identified. The remarkable plants included 11 taxa of the Korean endemic plants, such as Populus tomentiglandulosa, Salix koriyanagi, Cimicifuga heracleifolia, Aconitum pseudolaeve, Clematis trichotoma, Echinosophora koreensis, Vicia chosenensis, Salvia chanryoenica, and Hemerocallis hakuunensis. The rare plants designated by the Korea Forest Service were 4 taxa, including Echinosophora koreensis as endangered species (EC), Cimicifuga heracleifolia, Epimedium koreanum, and Lilium cernuum. The Least Concern species (LC) were 13 taxa, including Persicaria orientalis, Exochorda serratifolia, Viola diamantiaca, Lithospermum erythrorhizon, and Trigonotis icumae. The invasive alien plants were 28 taxa, including Persicaria orientalis, Rumex crispus, Phytolacca americana, Cerastium glomeratum, Chenopodium album, Chenopodium ficifolium, Amorpha fruticosa, Robinia pseudoacacia, Trifolium pratense, Trifolium repens, Oxalis dillenii, Euphorbia supina, and Oenothera biennis, accounting for 6.9 percent of the 403 taxa of the surveyed plants.

• Childhood Kidney Diseases
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• v.2 no.1
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• pp.77-81
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• 1998

The author exprienced a case of glycogen storage disease type Ia(GSD-I) in an 18-year-old male patient who was admitted to our hospital due to proteinuria and hypertension. he was suspected to have GSD when 12 years old because of his family history of short stature and hepatomegaly. On admission, physical examination revealed short stature, heparomegaly, and The diagnosis of GSD-I was confirmed by compatible liver biopsy finding and enzyme assay which erealeddeficiency of glcose-6-phosphatase if hepatocyte. Sympromatic treatment was done using antihypertensive drugs and allopurinol with diet control. The authors report a case of glycogen storage disease type Ia completely confirmed by typical clinical manifestation, pathologic findings of the liver and the kidney, and the result of enzyme assay which revealed deficiency of glucose-6-phosphatase in hepatocytes with brief review fo related literatures.

• Clinical and Experimental Pediatrics
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• v.49 no.3
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• pp.292-297
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• 2006

Purpose : In medulloblastoma, craniospinal radiation therapy combined with chemotherapy improves the prognosis of tumors but results in significant endocrine morbidities. We studied the endocrine morbidity, especially growth pattern changes. Methods : The medical records of 37 patients with medulloblastoma were reviewed retrospectively for evaluation of endocrine function and growth. We performed the growth hormone stimulation test in 16 patients whose growth velocity was lower than 4 cm/yr. Results : The height loss was progressive in most patients. The height standard deviation score (SDS) decreased from $-0.1{\pm}1.3$ initially to $-0.6{\pm}1.0$ after 1 year(P<0.01). Growth hormone deficiency(GHD) developed in 14 patients. During the 2 years of growth hormone(GH) treatment, the improvements of height gain or progressions of height loss were not observed. Twelve patients(32.4 percent) revealed primary hypothyroidism. One of six patients diagnosed with compensated hypothyroidism progressed to primary hypothyroidism. Primary and hypergonadotropic hypogonadism were observed in two and one patients respectively. There was no proven case of central adrenal insufficiency. Conclusion : Growth impairment developed frequently, irrespective of the presence of GHD in childhood survivors of medulloblastoma. GH treatment may prevent further loss of height. The impairment of the hypothalamic-pituitary-gonadal and hypothalamic-pituitary-thyroidal axis is less common, while central adrenal insufficiency was not observed.

• Sleep Medicine and Psychophysiology
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• v.2 no.1
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• pp.73-81
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• 1995

Objective : Patients with sleep apnea should be diagnosed with polysomnography(PSG). However, it is not easy to recommend PSG for all patients suspected with sleep apnea in practice. Therefore, we tried to develop the screening test for referral of PSG. Method : 140 patients with snoring and sleep apnea syndrome were studied by the PSG. Sleep apnea questionnaire. Zung's scale for depression. Stanford Sleepiness Scale(SSS), insomnia scale and neuropsychological test were administered. Also, blood pressure, height, weight and neck circumference were measured and some histories were taken. Correlations between respiratory disturbance index(RDI) and various parameters mentioned above and discriminant coefficients of the parameters to RDI were computed. And, we investigated sensitivities of screening tests for selection of the patients with RDI above 20. Results : Using six parameters(neck circumference, systolic blood pressure before sleep, degree of alcohol drinking, frequency of breath-holding during sleep, degree of dry mouth during sleep, sleep apnea score), the patients with RDI above 20 could be discriminated in 92.8% sensitivity. In case of more than two among six parameters(neck circumference of above 40cm, systolic blood pressure of above 125mmHg, frequent alcohol drinking, frequent breath-holding during sleep, frequent dry mouth during sleep, sleep apnea score of above 35), same patients could be discriminated in 87.6% sensitivity. And, in case of more than one among four parameters(neck circumference of above 40cm. systolic blood pressure of above 125mmHg, frequent alcohol drinking, body weight of above 80kg), discrimination sensitivity was 83.5%. Conclusions : Patients with RDI above 20 could be discriminated by above parameters with high sensitivity. Therefore, the screening test using above parameters can be applied in selection of the patients with sleep apnea for PSG in practice.

• Clinical and Experimental Pediatrics
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• v.51 no.12
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• pp.1329-1335
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• 2008

Purpose : This study aimed to determine the best cutoff line for insulin-like growth factor (IGF)-I and insulin-like growth factor binding protein (IGFBP)-3 to discriminate between growth hormone deficiency (GHD) patients and the control group. Methods : Two hundred thirty subjects with normal controls (129 boys and 101 girls, aged 7-15 years), 14 patients with complete GHD (12 boys and 2 girls), and 17 patients with partial GHD (9 boys and 8 girls) were studied. IGF-I serum concentrations were measured by radioimmunoassay (RI), and IGFBP-3 concentrations were measured by immunoradiometric assay (IRMA). Results : The receiver operating characteristic (ROC) plot analysis showed that the best IGF-I and IGFBP-3 cutoff line was at -1 standard deviation (SD). By comparing IGF-I serum levels of GHD children within 1 SD of normal control, we determined the sensitivity (S) (87.5-100%) and specificity (Sp) (80-84.6%) according to the age group. For IGFBP-3, we determined the following values: S (58.7-85.7%) and Sp (79.2-85.5%). Eleven of 14 patients with complete GHD (78.5%) and 16 of 17 patients with partial GHD (94.1%) had IGF-I concentrations equal to or below -1 SD of the control group mean. Ten of 12 complete GHD children (83.3%) and 13 of 17 partial GHD children (76.5%) had IGFBP-3 concentrations equal or below -1 SD of the control group mean. Conclusion : We conclude that the measurement of IGF-I and IGFBP-3 concentrations might provide essential supplementary data in the diagnostic evaluation of patients with GHD. Our results support the need to use cutoff lines based on below -1 SD of the control.