• Radiation Oncology Journal
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• v.8 no.1
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• pp.65-71
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• 1990

Between January,1974 and December 1980, fifty eight patients with locoregional recurrent breast carcinoma who did not have evidence of distant metastasis after initial treatment of surgery with or without adjuvant chemotherapy were treated with radiation therapy. Among them, five patients were excluded from this study because of incomplete record or incomplete treatment. The 5-year overall survival and disease free survival from the time of locoregional recurrence was $27\%\;and\;15\%$ respectively. In univariate analysis of prognostic variables, the clinical stage at initial diagnosis, recur duration, number of recurrence sites, size of recurrences, response to the treatment, remission duration were all found to have no significant effect on survival or disease free survival. On the other hand, menopausal status at initial diagnosis, number of positive node at initial surgery, whether or not the use of adjuvant chemotherapy after initial mastectomy had definite prognositc significance. In multivariate analysis of prognostic variables, remission duration, menopausal status at diagnosis, number of axillary node at mastectomy had definite prognostic significance. On the other hand, remission duration more than 12 months, premenopaus at initial mastectomy, less than four positive axillary lymph nodes at mastectomy predicted a good prognosis.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.1
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• pp.146-154
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• 2007

In this paper, we have presented a real-time transfer mechanism for the delay-sensitive data in WSNs (Wireless Sensor Networks). The existing methods for real-time data transfer select a path whose latency is shortest or the number of hops is least. Although the approaches of these methods are acceptable, they do not always work as efficiently as they can because they had no consideration for the link error rates. In the case of transmission failures on links, they can not guarantee the end-to-end real-time transfer due to retransmissions. Therefore, we have proposed an algorithm to select a real-time transfer path in consideration of the link error rates. Our mechanism estimates the 1-hop delay based on the link error rate between two neighboring nodes, which in turn enables the calculation of the expected end-to-end delay. A source node comes to choose a path with the shortest end-to-end delay as a real-time route, and sends data along the path chosen. We performed various experiments changing the link error rates and discovered that this proposed mechanism improves the speed of event-to-sink data transfer and reduces delay jitter. We also found that this mechanism prevents additional energy consumption and prolongs network lifetime, resulting from the elative reduction of transmission failures and retransmissions.

• Journal of the Korea Society of Computer and Information
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• v.18 no.6
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• pp.29-36
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• 2013

In wireless sensor networks, energy is the most important consideration because the lifetime of the sensor node is limited by battery. Most of the existing energy efficient routing protocols use the minimum energy path to minimize energy consumption, which causes an unbalanced distribution of residual energy among nodes. As a result, the power of nodes on energy efficient paths is quickly depletes resulting in inactive. To solve these problems, a method to equalize the energy consumption of the nodes has been proposed, but do not consider the link error rate in the wireless environment. In this paper, we propose a uniform energy consumption of cluster-based multi-hop routing mechanism considering the residual energy and the link error rate. This mechanism reduces energy consumption caused by unnecessary retransmissions and distributes traffic evenly over the network because considering the link error rate. The simulation results compared to other mechanisms, the proposed mechanism is energy-efficient by reducing the number of retransmissions and activation time of all nodes involved in the network has been extended by using the energy balanced path.

• Journal of Conservation Science
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• v.7 no.2
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• pp.60-67
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• 1998

The effects of moisture content (MC) and diffusion period on the diffusion of boron from borate rod through Pinus densiflora and P. koraiensis were investigated as a preliminary research of integrated remedial treatment for heritage wooden structures using borate rod. After equilibrating MCs of samples (15, 25, and 40%), borate rod (1,000 mg) was inserted into the sample, and stored for diffusion of boron at room temperatures ($23^{\circ}C$) for 2, 4, 8, and 12 weeks. Wafers were serially cut at constant intervals from rod treatment point and the boron penetration through longitudinal and transverse direction was measured by staining with boron indicator. For boron diffusion, MC above fiber saturation point was needed, and the diffusion rates increased with time. The fastest rates of diffusion were observed in longitudinal direction, followed by the radial and then the tangential direction. The rates of diffusion in all directions were the fastest in P. koraiensis. In P. densiflora, the diffusion rates through heartwood was faster than that in sapwood in longitudinal direction and vice versa in transverse direction. Based on the best result of this study, optimal space between rod insertion points could be recommended as follows; approximately 120 mm for P. koraiensis and heartwood of P. densiflora, 60 mm for sapwood of P. densiflora in longitudinal direction, and approximately 30 mm for all species tested in transverse direction. However, the effect of rod size and long-term exposure for diffusion on boron movement should be fully investigated for the accurate evaluation of optimal space between rod holes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.594-601
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• 2019

A true MSEW abutment is an abutment type that directly supports the load of a superstructure. Metal strips, which are in-extensile reinforcements, should be used to minimize abutment deformation. A study to derive the application conditions of a True MSEW abutment was carried out by Zevogolis(2007). As a result, the pullout factor of safety of the uppermost reinforcement was estimated to be the smallest. Therefore, the pullout factor of safety of the uppermost reinforcement is the most important design factor. Parameter analysis was conducted with the abutment length, abutment heel, and abutment height as variables. The pullout factor of safety increased with increasing abutment length and abutment heel length. This is because the contact area increases and the superstructure is dispersed as the abutment length and abutment heel length increase. The pullout factor of safety converges at an abutment length of 1.2m and an abutment heel length of 0.9m. This is because the effective length of the reinforcement is reduced due to the increase in contact area. On the other hand, the extension of the superstructure will increase if the abutment length and abutment heel length are increased excessively. In addition, earth-volume is increased if the abutment height increases excessively. This acts as an upper load on the MSE wall. Therefore, it needs to be examined carefully.

• Tuberculosis and Respiratory Diseases
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• v.40 no.4
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• pp.367-377
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• 1993

Background: The benefits of combination chemotherapy in unresectable non-small cell lung cancer remain uncertain. But, according to the recent reports, the response rates of cisplatin-based polychemotherapy regimens are higher than those of single agent. Also, the response rates of high-dose cisplatin group are higher than those of low-dose cisplatin group. In attemp to answer the question whether treatments, combination chemotherapy (high VPP) and combination chemotherapy with radiation therapy, improve survival in advanced non-small cell lung cancer, we begin to study. Method: Thirty-five patients above stage III, diagnosed histologically as non-small cell lung cancer, were enrolled. Among them, nineteen received a combination chemotherapy consisting of VP-16 & high-dose cisplatin (100 $mg/m^2$) and/or radiation therapy. The other group (16 subjects) received no therapy. To investigate the differences of survival and response rates between two groups and the side effects related to therapy, we reviewed patients' records. Results: 1) The overall objective response rate was 47%(9/19) with one complete remission. 2) In patients who received polychemotherapy and radiation therapy, the response rate was 60%(6/10) with one complete remission and survival rates of 3 months, 6 months and 12 months were 100%, 70% and 40%. 3) In patients who received polychemotherapy, the response rate was 33% (3/9) with no complete remission and survival rates of 3 months, 6 months and 12 months were 78%, 67% and 33%. 4) Overall, treated patients survived significantly longer (p<0.05) than non-treated patients (median survival 307 days versus 95 days). 5) Analysis of the various prognostic factors disclosed that good performance status, stage III and squamous cell type showed the good response rates. 6) The toxicities were nausea and/or vomiting (100%), alopecia (90%), anemia (79%), leukopenia (69%), thrombocytopenia (2%), increased creatinine (16%) and neurotoxicity (5%). Conclusion: According to above results, there are relatively good results that high VPP combination chemotherapy in advanced non-small cell lung cancer improves survival in the treated group than in the non-treated group. Thus, it is considerd that we select the patients with proper indications and treat them with effective chemotherpy and radiation therapy. But, because improvement related to high VPP ploychemotherapy is not marked in this study, it is necessary that we should investigate follow-up studies in many cases.

• Journal of Ginseng Research
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• v.10 no.1
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• pp.27-35
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• 1986

This study was devised to observed the growth inhibition and change of disaccharidase activities of human colon cancer cells cultured in medium containing the ginseng extract. Three species of human colon cancer cell lines, HRT-18, HCT-48 and HT-29, were used for the experiment. The activities of sucrease, lactase, maltase and trehalase in the cancer cells were determined. The results obtained are summarized as follows; 1. The doubling times of the HRT-18, HT-29 and HCT-48 were about 20,22 and 24 hours, respectively. 2. The growth rates of the HRT-18 and HCT-48 in culture medium containing the ginseng extract were inhibited gradually according to increase of the concentration of ginseng extract and extension of the incubation time. 3. The activities of disaccharidase in HRT-18 and HCT-48 cultured in the medium containing the ginseng extract were increased compared with control group as follows;

• Journal of the Korean Geosynthetics Society
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• v.14 no.2
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• pp.11-21
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• 2015

According to the damage investigation in 2002, the failures of river levee were caused by overflow, erosion, and unstable body conditions due to piping, inappropriate embanking materials, and poor compaction. Especially, overflow was identified as a main reason that induces levee failure by 39.5% from the distribution of failure types. The major parameters, such as levee collapsing angle (${\theta}$), levee collapsing rate (k) affect inundation velocity and area size during the analysis of inundation modeling, however, domestic research effort on this area is still insufficient. In this paper authors conducted levee failure experiments of 4 levee height types, 0.20 m, 0.25 m, 0.30 m, and 0.40 m based on theassumption of Froude Similarity (${\lambda}_{Fr}=1$). As a result, the authors suggested a levee failure mechanism according to the levee heights (H), a collapse extension lengthwhich is around, levee collapse angle (${\theta}$), levee collapse rate (k).

• KSBB Journal
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• v.16 no.1
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• pp.24-29
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• 2001

Recently hepatocyte-based bioartificial liver (BAL) and hepatocyte transplantation have been actively investigated to treat acute hepatic failure. The BAL acts as a bridge to provide patients with more time until a donor organ becomes available for transplantation or until their own liver can be regenerated. In this study, we manufactured a polyurethane foam (PUF) using 15% NCO-prepolymer with a pore opening that allows it to be used as a hepatocyte immobilizing material. Cubes of PUF (3 mm dim.) were seeded with rat primary hepatocytes at a density of 5.5$\pm$1.1$\times$ $10^6$ cells/$cm^3$ PUF by centrifuging them together. The cell laden PUF cubes were packed into a prototype reactor and perfused with a hormonally defined medium for a week. Hepatocytes in the pores of the PUF formed spheroids that showed stable ammonia removal and urea synthesis activities. The albumin production level was comparable to other BAL systems. The PUF packed hepatocyte bioreactor has the potential to be used as a BAL.

• Explosives and Blasting
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• v.31 no.2
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• pp.32-39
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• 2013

Generally, The way of long hole blasting is carried out in coal-face, basic excavation for dam, mine etc. Recently, this long hole blasting has been implemented in civil engineering for efficiency & economic feasibility. National express no.600 of Pusan outer high-express ${\bigcirc}$ construction site with four lanes of the length of 8km was also a site applied by long hole blasting. But After blasting, tunnel advance rate is less than 75%. As a result of that, Follow-up working time is influenced. Thereby, The total of working process is significantly so increased that planned excavation cannot be implemented many times. For not only improve excavation rate but reduce working process time in job site, we introduce blasting case which apply the ${\phi}36mm$ explosive suited for high desity of charging among long hole blasting in order to overcome mentioned problem.