• Journal of the Korea Academia-Industrial cooperation Society
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• 제10권3호
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• pp.634-641
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• 2009

This study conducted to find concordance of hypertension in older couples. For these purposes, the researcher conducted surveys of 297 couples residents in a rural area, Geumsan-gun, Chungcheongnam-do during January and February 2006. Risk factors differed from between couples were smoking, alcohol drinking, triglyceride that were higher in men; stress and LDL higher in women. Wife's risk factors of hypertension related to husband's risk of hypertension were metabolic syndrome (OR=2.879) and current alcohol drinking (OR=1.892). Husband's risk factors of hypertension related to wife's risk of hypertension were age (OR=1.037), Obesity (OR=1.922), metabolic syndrome (OR=4.100), and triglyceride (OR=1.793). Conclusively, important risk factors affecting hypertension of couples living in a rural area were age, metabolic syndrome, and body mass index. It needs to care these factors closely.

• Journal of Preventive Medicine and Public Health
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• 제25권2호
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• pp.148-156
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• 1992

A case-control study was conducted to investigate the relationship between blood cadmium, blood zinc and cadmium/zinc ratio and hypertension. Eighty-three hypertensive and seventy-seven normotensive study subjects matched for age and sex were selected from the workers who had no history of job-related cadmium exposure, in Ulsan city and it's vincinity, Korea. The blood cadmium in hypertensive group was $2.90{\eta}g/mL$, which was significantly higher than that of control group, $1.99{\eta}g/mL$(P<0.01). After stratifing for smoking and age variables, the relationship was still remained. The blood cadmium/zinc ratio in hypertensive group was 2.46, which was significantly higher than that of control group, 1.65(P<0.01), After stratifing for smoking and age variables, the relationship was still remained. There was no significant differance in blood zinc between hypertensive and control group. On multiple logistic regression analysis, the blood cadmium/zinc ratio is highly significant than blood cadmium. In conclusion, there is the possible relationship between blood cadmium level which has been known to be within normal limits and hypertension. But, futrher cohort studies to define the effect of cadmium on human hypertension are required.

• The Korean Journal of Applied Statistics
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• 제30권3호
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• pp.475-486
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• 2017

This paper estimates the health life expectancies for Korean people based on a sample cohort database collected through objective measurements by the National Health Insurance Service. Health life expectancy is estimated using the single-state approach of Sullivan (1971). The 9-order correction factor method of Greville (1945) and Brass-logit model of Brass (1971) are also adopted for unobserved or incompletely observed age-specific morbidity and mortality. Based on the mortality and morbidity estimated from sample cohort DB, men and women in Korea are expected to live a 'healthy life' for 61 and 60 years in 2013, respectively, whereas life expectancies of men and women are 80 and 87, respectively. We also estimate certain disease-free life expectancies for each of genders, income levels, and types of insurance from 2003 to 2013 in Korea. We found that there exists an inequality of healthy life expectancy in Korea for different genders, income levels, and types of insurance.

• Journal of the Korean Society of Food Science and Nutrition
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• 제43권10호
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• pp.1467-1476
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• 2014

Recent studies have shown that insufficient or deficient vitamin D status may be linked to increased risk of depressive conditions or depression. The aim of this study was to review all available evidence on vitamin D, depression, and any association between them. Cross-sectional, case-control, and cohort studies have reported contradictory results. Some have reported that low levels of vitamin D may be associated with higher risk of depression or depressive symptoms while others reported that vitamin D status may not be related to depression. Recent clinical trials examining the effects of vitamin D supplementation on depression have also showed discrepant results. However, meta-analysis study results are consistent regarding the beneficial effects of vitamin D. Several mechanisms that account for these beneficial effects of vitamin D on depression have been reported but remain largely speculative. Vitamin D deficiency is very common, and prevalence of depression is increasing in the Asian population, especially females. However, limited literature is available on this population. Considering research results of a potential inverse association between vitamin D level and prevalence of depression, it is important to advance our understanding of the role of vitamin D in depression and conduct well-designed prospective trials in the Asian population.

• Journal of the Korea Convergence Society
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• 제13권2호
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• pp.349-356
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• 2022

This study aims to identify factors related to suicide within one year of schizophrenia diagnosis based on data from National Health Information Database. We obtained data of 102,540 patients diagnosed with schizophrenia between 2007 to 2010 from customized database, which was checked using the National Statistics Organization database and schizophrenia cohort was built. The number of suicide within one year of schizophrenia diagnosis was 615(0.60%), and the risk of suicide within one year was high among patients within age group of 25-34 and patients with medium-low to high economic status. The risk of suicide within one year among male patients was high within age group of 45-54 and patients with medium-low to high economic status. The risk of suicide within one year among female patients was high within patients with high economic status. Age and economic status need to be considered during suicide prevention intervention of schizophrenia patients diagnosed within one year and suicide related factors by sex need to be especially considered.

• Therapeutic Science for Rehabilitation
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• 제12권4호
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• pp.111-122
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• 2023

Objective : To identify the effect of lifestyle risk factors on the daily activities and cognition of the older adults in the community using the National Health Insurance Corporation 2015 geriatric cohort database. Methods : Lifestyle risk factors were defined as body mass index (BMI), smoking, drinking, vigorous exercise, moderate exercise, and walking, and basic and instrumental activities of daily living (ADL) and cognitive function variables were included in the analysis. ADL and cognitive function according to sex and age were analyzed using a t-test and one-way ANOVA. The correlation between lifestyle risk factors, ADL, and cognitive function was analyzed using Pearson's correlation analysis, and multiple regression analysis was performed to analyze their influence. Results : The factors affecting basic ADL (BADL) were sex and walking exercises, with an explanatory power of 1.7%. Instrumental ADL (IADL) included age, drinking, and walking exercises, with an explanatory power of 2.6%. Cognitive function included sex, age, BMI, vigorous exercise, and walking, with an explanatory power of 5.3%. Conclusion : Lifestyle risk factors partially affected BADLs/IADLs and cognitive function in community-dwelling older adults. This suggests the need to systematically manage lifestyle risk factors to improve and maintain the healthy lives of older adults facing biological aging.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제18권3호
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• pp.105-114
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• 2017

The purpose of this study was to examine the effects of obesity at diagnosis on the prognosis of Korean breast cancer patients after classifying them according to their reproductive history and age by comparing the overall survival rate (OS) and disease-free survival rate (DFS). This study is a retrospective cohort study using 4181 breast cancer cases at one of the medical centers in Korea during the 3 year period from 2006 to 2008. We confirmed the levels of death and recurrence through a follow-up study completed in May 30. 2015. In conclusion, the parous patients had a lower OS than the non-parous patients (p=.000), and the younger patients below 40 years old had a lower OS and DFS than those who were 40 years old or older (p=.003, p=.000), while obesity did not affect the OS and DFS significantly. However, several subgroups in which obesity affected the OS and DFS were found after classifying the patients according to their reproductive history and age. For the subgroups classified by reproductive history, the obese patients had a lower OS and DFS than the non-obese patients in the subgroup in which the patients have a reproductive history (p=.001, p=.005). For the subgroups classified according to age, the obese patients had a lower OS and DFS than the non-obese patients in the subgroup in which the patients were 40 years old or older (p=.005, p=.014). Obesity affected the OS and DFS in the subgroup in which the patients were 40 years old or older and had a reproductive history (p=.000, p=.003). The results of this study show that obesity has an effect on the prognosis of breast cancer patients in the subgroups classified by reproductive history and age, whereas it has no effect on the OS and DFS of the patients when they are examined in their entirety. It also suggests that appropriate nursing intervention is needed for the subgroups in which obesity has effects on prognosis.

• Pediatric Infection and Vaccine
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• 제31권1호
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• pp.25-36
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• 2024

Purpose: Tetracycline is not recommended for children under 12 by guideline due to the risk of tooth discoloration. We aimed to assess the incidence of dental discoloration in Korean children prescribed tetracyclines and investigate whether its risk was greater in tetracycline-exposed children than in the general population. Methods: This population-based cohort study using the Health Insurance Review and Assessment service database included children aged 0-12 years exposed to tetracyclines for at least 1 day between January 2008 and December 2020. The primary outcome was the incidence rate of dental discoloration ≥6 months after prescription, and the standardized incidence ratio (SIR) was evaluated as secondary outcome. Results: 56,990 children were included-1,735 and 55,255 aged <8 and 8-12 years, respectively. 61% children were prescribed tetracycline for <14 days with mostly second-generation tetracyclines, doxycycline (61%) and minocycline (35%). The 5- and 10-year cumulative incidence rates of dental discoloration were 4.1% (95% confidence interval [CI], 3.0-5.7%) and 5.7% (95% CI, 4.1% to 7.8%), respectively, in the 0-7 years age group and 0.8% (95% CI, 0.7% to 0.9%) and 1.3 (95% CI, 1.1% to 1.4%), respectively, in the 8-12 years age group. Tetracycline exposure did not increase such risk compared to that in the general population (SIR, 1.08; 95% CI, 0.69 to 1.60). Conclusions: The incidence of dental discoloration was lower than previously suggested. Relieving the age restriction for prescribing tetracyclines may be considered.

• Journal of the Korean Society of Food Culture
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• 제14권4호
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• pp.371-383
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• 1999

This report gave analysis of food demand both in Korea and Japan through introducing the concept of cohort analysis to the conventional demand model. This research was done to clarify the factors which determine food demand of the household. The traits of the new model for demand analysis are to consider and quantify those effects on food demand not only of economic factors such as expenditure and price but also of non-economic factors such as the age and birth cohort of the householder. The results of the analysis can be summarized as follows: 1) The comparison of the item-wise elasticities of food demand demonstrates that the expenditure elasticity is higher in Korea than in Japan and that the expenditure elasticity is -0.1 for cereal and more than 1 for eating-out in both countries. In respect to price elasticity, the absolute values of all the items except alcohol and cooked food are higher in the Korea than in Japan, and especially the price elasticities of beverages, dairy products and fruit are predominantly higher in Japan. In this way, both expenditure and price elasticities of a large number of items are higher in Korea than in Japan, which may be explained from the fact that the level of expenditure is higher in Japan than in Korea. 2) In both of Korea and Japan, as the householder grows older, the expenditure for each item increases and the composition of expenditure changes in such a way that these moves may be regarded as due to the age effect. However, there are both similarities and differences in the details of such moves between Korea and Japan. Those two countries have this trait in common that the young age groups of the householder spend more on dairy products and middle age groups spend more on cake than other age groups. In the Korea, however, there can be seen a certain trend that higher age groups spend more on a large number of items, reflecting the fact that there are more two-generation families in higher age groups. Japan differs from Korea in that expenditure in Japan is diversified, depending upon the age group. For example, in Japan, middle age groups spend more on cake, cereal, high-caloric food like meat and eating-out while older age groups spend more for Japanese-style food like fish/shellfish and vegetable/seaweed, and cooked food. 3) The effect of the birth cohort effect was also demonstrated. The birth cohort effect was introduced under the supposition that the food circumstances under which the householder was born and brought up would determine the current expenditure. Thus, the following was made clear: older generations in both countries placed more emphasis upon stable food in their composition of food consumption; the share of livestock products, oil/fats and externalized food was higher in the food composition of younger generation; differences in food composition among generations were extremely large in Korea while they were relatively small in Japan; and Westernization and externalization of diet made rapid increases simultaneously with generation changes in Korea while they made any gradual increases in Japan during the same time period. 4) The four major factors which impact the long-term change of food demand of the household are expenditure, price, the age of the householder, and the birth cohort of the householder. Investigations were made as to which factor had the largest impact. As a result, it was found that the price effect was the smallest in both countries, and that the relative importance of the factor-by-factor effects differed among the two countries: in Korea the expenditure effect was greater than the effects of age and birth cohort while in Japan the effects of non-economic factors such as the age and birth cohort of householder were greater than those of economic factors such as expenditures.

• Journal of the Korea Academia-Industrial cooperation Society
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• 제13권3호
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• pp.1186-1193
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• 2012

The purpose of the study is to provide the basic data for preventing and caring cardiovascular disease. The study was performed with the data from the same 1,668 persons who had medical checkup three times from 2004 to 2008 at a health promotion center. The related factors were examined with Cohort Study. The result of the study is as followed, The incidence of metabolic syndrome for the subjects from 2004 to 2008 increased; 0% in 2004, 8.3% in 2006 and 12.0% in 2008. Multiple logistic regression analysis showed that the related factors in the occurrence of metabolic syndrome which changed from the non metabolic syndrome group in 2004 to metabolic syndrome were age, smoking, total cholesterol, ALT, and uric acid etc.