• Journal of radiological science and technology
• /
• v.32 no.4
• /
• pp.461-469
• /
• 2009

To predict the tumor grading, various imaging modalities have been applied clinically. This study determines clinical usefulness of perfusion MRI, using relative cerebral blood volume in grading of the gliomas. We did a retrospective review of 17 patients (mean age, 57.5 years; 11 male, 6 female) who underwent perfusion MR and conventional MRI, and then correlated pathologically after operation. Statistical analysis of regional cerebral blood volume and relative cerebral blood volume(rCBV) was performed by using softwares such as PAT by SIEMENS and Xmap ver 2.0 developed by ourselves. Six patients out of 13 were low-grade gliomas while eleven patients were the high-grade gliomas. Mean relative CBV (m_rCBV/white matter) in the low-grade gliomas was 1.62, and mean relative CBV(m_rCBV/cortex) was 0.12. In the high-grade gliomas, mean relative CBV(m_rCBV/white matter) and mean relative CBV(m_rCBV/cortex) were 33.53 and 0.96. Mean relative CBV of gliomas were elevated with a statistical difference(P<.05), compared with contralateral white matter(P=.019) or cortex(P=.025). Furthermore mean relative CBV(m_rCBV/white matter) was much higher than mean relative CBV(m_rCBV/cortex). Perfusion MRI using regional cerebral blood volume and rCBV is very useful imaging modality for grading the glioma.

• Radiation Oncology Journal
• /
• v.13 no.1
• /
• pp.1-7
• /
• 1995

Purpose : To evaluate the efficacy of radiotherapy for the low-grade astrocy-tomas and confirm the variables influencing treatment results. Materials and Methods : Forty-six patients with low-grade astrocytoma received radiotherapy after surgical removal (36 patients) or biopsy (10 patients) from 1979 to 1990. Twenty patients had grade I histology and 26 had grade II. External radiotherapy was done by conventional schedule with the total dose of 45 to 60 Gy (median: 54 Gy). The median follow-up period was 5 years. Results : The 2- and 5-year survival rates were $80\%$ and $72\%$, respectively and the 2- and 5-year progression-free survival was $75\%$ and $63\%$, respectively. The survival was influenced significantly by the histologic grade, the histologic type, and performance status. Major complication was not found. Conclusion: In spite of good survival, the local failure was still the major problem. Age and the extent of surgery as well as three favorable factors should be considered in the future treatments.

• Clinics in Shoulder and Elbow
• /
• v.11 no.2
• /
• pp.96-103
• /
• 2008

Purpose: This study investigated the rate of retear and related factors after arthroscopic repair of rotator cuff tears involving more than one tendon. Materials & Methods: Arthroscopic repair of 22 rotator cuff tears (average size 3.2cm: average age 58 years old) involving the supraspinatus and part or all of the infraspinatus were investigated using MRI on average 10 months after repair. The status of the repaired cuff was investigated using Sugaya's classification, and the change in muscle was evaluated with Goutallier's classification. Results: Retear (Sugaya grade IV, V) was found in 7cases(32%). Tears larger than 3cm had a higher retear rate(67%) than smaller tears(8%). Retear cases had Goutallier grade II or higher muscle changes preoperatively and showed aggravation of muscle atrophy postoperatively. Even without retear, reversal of muscle change was not seen Conclusion: Rotator cuff tears not confined to the supraspinatus had a 32% retear rate after arthroscopic repair. The size of the tear was the most crucial factor influencing retear. Retear was frequent in tear over 3cm. Atrophy of the cuff muscle worsened when the repair failed but did not improve even without retear.

• The Journal of the Korea Contents Association
• /
• v.17 no.2
• /
• pp.38-46
• /
• 2017

This research aimed to identify the correlation between the metabolic syndrome, which is one of the cardiovascular risk factors and emerging as an issue in the society, and the serum uric acid level. The research was conducted on a total of 1,444 patients who took a medical examination at a health examination center. The research subjects were composed of 977 men and 467 women. By conducting physical measurement and the blood test on the subjects, the research identified the correlation between the serum uric acid level and the metabolic syndrome and compared the number of the risk factors by dividing the class of the serum uric acid. The average level of serum uric acid was identified higher in men at $6.30{\pm}1.39mg/dL$ than $4.43{\pm}0.89mg/dL$ in women. Men had a correlation between age, waist size, systolic blood pressure, neutral fat, HDL-cholesterol, WBC count and ESR and the serum uric acid level (p<0.05), while women had a correlation between waist size, diastolic blood pressure level, neutral fat, HDL-cholesterol and ESR and the serum uric acid level (p<0.05). The number of the risk factors depending on the serum uric acid level increased as the serum uric acid level rose. The overall prevalence rate of the metabolic syndrome was higher in men at 17.4% than 10.2% in women. This showed that there is a statistically relevant relevance between the metabolic syndrome and the serum uric acid level, and the number of the risk factors of the metabolic syndrome will go up with an increase in the serum uric acid level.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.45 no.2
• /
• pp.170-178
• /
• 2018

Behavior management of the child constitutes an important part of pediatric dentistry. The majority of children can be treated with adequate behavior management. However, some children who have extensive dental problems or mental, physical disabilities cannot cooperate. So, the need for general anesthesia as a special method of behavior management has increased recently. This study analyzes the records of patients who received dental treatment under general anesthesia. The 1378 cases of 1322 patients under 18 years of age, who received dental treatment under general anesthesia in department of pediatric dentistry at the Seoul National University dental hospital, from October, 2011 to December, 2015 were included. In this study, male (60.9%) was more than female (39.1%). The mean age of patients was 5.9 years and age from 5 to 9 years was the most frequent (56.0%). The primary dental treatment which patients received was dental caries treatment (51.1%), followed by surgical treatment (42.2%). The dental treatment under general anesthesia has many advantages including of performing a lot of treatments at once, producing good quality of treatment, and reducing the number of visits. General anesthesia may be a useful method of behavior management.

• Journal of Digital Convergence
• /
• v.11 no.12
• /
• pp.599-606
• /
• 2013

The purpose of this study is to know a clinical usefulness for delineation of articular cartilage compared with 2D TSE-SPIR and 3D FFE-PROSET technique. From January 2013 to september 2013, a total of 30 normal volunteers(12 men and 18 women aged between 35 and 55 years; mean 49.48 years) were studied on a philips 3.0T MRI scanner. As a quantitative analysis, SNRs and CNRs were evaluated by using two methods for delineation of articular cartilage. As a qualitative analysis, image quality was evaluated by special radiological technologist of MRI for image delineation on a three grade. As a results, SNRs and CNRs for articular cartilage were significantly greater for the 3D FFE-PROSET(SNRs: 8.40, 114.02, 9.53, CNRs: 104.49, 139.49) technique compared to 2D TSE-SPIR(SNRs: 4.41, 71.63, 7.34, CNRs: 64.30, 58.41) technique, image quality also was higher for evaluation of 3D FFE-PROSET(2.40) technique(p=0.0021). In conclusion, this study showed that a 3D FFE-PROSET MRI has improved SNRs and CNRs for evaluating of the articular cartilage, these conclusions in the future will be provided useful information in diagnosis of articular cartilage.

• Pediatric Infection and Vaccine
• /
• v.18 no.1
• /
• pp.68-79
• /
• 2011

Purpose : This post-marketing surveillance study (NCT00750360) assessed the safety and reactogenicity of an inactivated, trivalent split-virion influenza vaccine licensed for use in the Korea since 2002. Methods : Eight hundred and eighty three subjects aged 6 months received a single dose of the ${\geq}$ vaccine; an additional dose was administered to those aged <9 years and unprimed with an influenza vaccine. Four hundred and eleven subjects used diary cards to record safety information; this report presents data from these subjects. Incidence of solicited local, general and unsolicited adverse events (4-days and 21-days post-vaccination follow-up periods, respectively) were recorded. Serious adverse events (SAEs) were recorded throughout the study period. Results : Injection site pain (subjects aged <6 years: 12.6% of subjects, ${\geq}$6 years: 34.7%), fever (<6 years: 1.3%) and myalgia (${\geq}$6 years: 13.9%) were the most frequently recorded solicited local and general adverse events. Grade 3 solicited adverse events were reported by ${\leq}$4.0% subjects. No vaccine-related SAEs were recorded (KFDA criteria). Conclusion : Considering the vaccine's well-established immunogenicity and its favourable safety and reactogenicity profile across all age groups and its high coverage rate in Korea, it may be recommended as a candidate to facilitate annual seasonal influenza vaccination for all ages as part of the Korean National Immunization Program.

• Journal of Chest Surgery
• /
• v.31 no.3
• /
• pp.221-225
• /
• 1998

From February 1996 to May 1997, 18 patients underwent mitral valve repair for mitral regurgitation. There were 9 male and 9 female patients aged from 19 to 68 years(mean, 53). Thirteen patients were in New York Heart Association(NYHA) class III and IV. The cause of mitral regurgitation was degenerative in 12 patients, rheumatic in 5 patients and infective in 1 patient. Fifteen patients were in Carpentier's functional classification II, 2 patients in Carpentier's class III and 1 patient in Carpentier's class I. Surgical procedures included prosthetic ring annuloplasty(16 cases), rectangular resection of posterior leaflet(15 cases), chordal shortening(5 cases), triangular resection of anterior leaflet(2 cases), commissurotomy(2 cases), partial transposition of posterior leaflet(1 case). These procedures were combined in most patients. There was no operative death. These patients have been followed from 1 to 15 months, mean of 6.7 months. There was one late death resulted from low cardiac output following mitral valve replacement. The function of the repaired valve in other 17 patients has remained satisfactory during the observed interval. We consider that mitral valve repair is highly satisfactory in patients with mitral regurgitation.

• Journal of the Korea Convergence Society
• /
• v.9 no.1
• /
• pp.387-392
• /
• 2018

The aim of this study was to determine the statistical significance of heart rate variability(HRV) between sleep stages, Apnea-hypopnea index(AHI) and age in patients with obstructive sleep apnea(OSA). This study evaluated the main parameters of HRV over time domain and frequency domain in 40 patients with sleep apnea. The non-REM(sleep stage) was statistically validated by comparing the AHI degree of the three groups(mild, moderate, severe) of sleep apnea patients. The NN50(p=0.043), pNN50(p=0.044), VLF peak(p=0.022), LF/HF(p=0.028) were statistically significant in the R-R interval of patients with sleep apnea from the control group (p<0.05). The LF / HF (p = 0.045) and HF power (p = 0.0395) parameters between the non-RAM sleep (sleep 2 phase) and REM sleep in patients with sleep apnea were statistically significant in the control group(p<0.05). We may be able to provide a basis for understanding the correlation among AHI, sleep stage and age and heart rate variability in patients with obstructive sleep apnea.

• Korean Journal of Social Welfare
• /
• v.69 no.3
• /
• pp.193-212
• /
• 2017

This study is purposed to explain the characteristics of injured workers' labor market situation and to analyze the factors influencing labor market transition of those workers. Using the Worker's Compensation Insurance Panel Data ver.1~3 which was surveyed by the Korean Workers' Compensation & Welfare Service in 2013-2015, this study analyzed 1,668 injured worker cases. The study shows that workers who have experience job retention at least once are 36.8% of all, 51.5% of them have experienced re-employment, and 36.9% have done unemployment. One result of the longitudinal analysis is that socio-demographic factors including gender, age, education years, convalescence period, ability on job performance, company size, term of service, temporary employment, daily-workers status before job accident and job training were associated with return to pre-injury job. The other result is that statistically significant factors affecting the probability to be the unemployed are gender, age, levels of disability, convalescence, ability on job performance, term of service before job accident, job rehabilitation service utilization. These findings indicate that we need to develop efficient intervention programs for supporting return-to-work and labor market transition of injured workers.