• Title/Summary/Keyword: 에피네피린

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Electrochemical Determination of Epinephrine Using Doubly Modified Electrodes with Ni(II)-Macrocyclic Complex and Polyuretane (니켈(II)-거대고리 착물과 폴리 우레탄으로 변성한 이중 전극에서 에피네피린의 전기화학적 정량)

  • Xu, Guang-Ri;Cho, Hyung-Hwa;Kweon, Soo-Geong;Lee, Sang-Hag;Bae, Zun-Ung
    • Journal of the Korean Electrochemical Society
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    • v.10 no.3
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    • pp.190-195
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    • 2007
  • A new electrochemical sensor to selectively determine epinephrine was developed and its analytical characteristics has been investigated. A glassy carbon electrode was modified with Ni(II)-macrocyclic complex which has electrocatalytic effect. It was further modified with physiologically suitable and negatively charged polyuretane benzyl L-glutamate(PUBLG). The present electrode showed long term stability and it could be applied to the selective determination of epinephrine in urine sample with various coexisting compounds. Under the optimum experimental conditions the linear range was $8.0\;{\times}\;10^{-7}\;-\;2.0\;{\times}\;10^{-4}\;M$ and the limit of detection was $1.0\;{\times}\;10^{-7}\;M$. The recovery of epinephrine in urine sample diluted 5 times with buffer solution was $101.5({\pm}3.2)%$ for 6 measurements.

Effects of Low Intensity Muscle Training on Norepinephrine, Epinephrine, and Serotonin Level in Stroke Patients with Depression and Emotional Incontinence (저강도 근력 운동이 우울증 및 감정 조절 장애가 있는 뇌졸중 환자의 노르에피네피린, 에피네피린, 그리고 세로토닌에 미치는 영향)

  • Hong, Soungkyun;Lee, Donggeon;Lee, Gyuchang
    • Journal of The Korean Society of Integrative Medicine
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    • v.6 no.2
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    • pp.69-76
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    • 2018
  • Purpose : This study investigated the effects of low-intensity muscle training on neurotransmitters associated with depression and emotion regulation disorders in survivors with stroke who were diagnosed with depression or emotion regulation disorder. Methods : Survivors of chronic stroke diagnosed with depression or emotion regulation disorder (n = ) were included in the study. Concentrations of serotonin, norepinephrine, and epinephrine were measured before and after. Low-intensity muscle training was performed once a day for 50 minutes, 5 times a week for 10 weeks. Result : Levels of serotonin, norepinephrine, and epinephrine improved significantly after intervention (p < .05). Conclusion : These results confirm that low-intensity muscle training has a positive effect on neurotransmitter concentrations in survivors with stroke diagnosed with depression and emotion regulation disorders. Future studies should analyze the changes in neurotransmitters in more detail using various exercise methods and intensities to investigate their effects on depression and emotion regulation disorders.

Influence of Epinephrine and Norepinephrine on the Risk of Metabolic Syndrome Occurrence in Workers Exposed to Hazardous Chemicals (유해화학물질 노출 근로자의 대사증후군 발생위험에 대한 epinephrine과 norepinephrine의 영향)

  • Heo, Kyung-Hwa;Kim, Ki-Woong
    • Korean Journal of Occupational Health Nursing
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    • v.19 no.1
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    • pp.88-96
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    • 2010
  • Purpose: The aim of the present study was to clarify effects of long term, low-level monocyclic aromatic hydrocarbons exposure (MAHs) such as styrene, toluene and xylene on physiological levels of epinephrine (EP) and norepinephrine (NEP) and these hormones influences diagnosis indices of metabolic syndrome (MetS). Methods: Blood pressure and serum biochemical parameters were measured using digital sphygmomanometer and autochemical analyzer. EP and NEP were analyzed by using ELISA kit and exposure level of MAHs was measured by NIOSH method. Results: The differences of general characteristics such as age, smoking and drinking habits in both groups were not significantly different except working hours per day. In exposed workers, exposure levels of MAHs showed very low concentrations. Serum HDL-cholesterol concentration was significantly higher in exposed group, but concentration of NEP was significantly higher in control group. On multiple logistic regression analysis for the diagnosis indices of MetS, EP was WC (OR=0.970), NEP was blood pressure (OR=1.002) and MAHs exposure were significantly associated with HDL-cholesterol (OR=0.257), fasting glucose (OR=3.028) and MetS (OR=0.372). Conclusion: These findings suggest that the chronic exposure of low level MAHs maycontribute to glucose metabolism and induction of MetS. And also, changes of EP and NEP levels by exposure of MAHs affect blood pressure.

Roles of Epinephrine and Insulin in the Regulation of Metabolism in Dairy Cow (젖소에서 epinephrine 및 insulin에 의한 대사 조절)

  • Kim, Jin-Wook
    • Journal of agriculture & life science
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    • v.43 no.4
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    • pp.15-20
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    • 2009
  • The transition from pregnancy to lactation, commonly referred to as the "transition period" is characterized by dramatic changes in metabolic processes and their regulation in order to prepare the dairy cow for parturition and lactogenesis. An important adaptation to lactation is the increase in gluconeogenesis by the liver to meet the tremendous increase in demand of glucose for lactose synthesis, and the accumulation of lipid in adipose tissue during pregnancy, its mobilization that begins prior to lactation and the dramatic increase in plasma NEFA concentration early lactation. Epinephrine and insulin, the homeostatic regulators of metabolism are responsible for the adaptations of lipid and carbohydrate metabolism in support of milk production along with mobilization of body fat to meet overall energy demands because dry matter intake is insufficient to meet these demands during early lactation.

Meta-Analysis about Effect of Aromatherapy on Stress (향기요법이 스트레스에 미치는 효과에 대한 메타 분석)

  • Kim, Gyung-Duck;Suh, Soon-Rim
    • Journal of Hospice and Palliative Care
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    • v.11 no.4
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    • pp.188-195
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    • 2008
  • Purpose: The purpose of this study was to analyze the effects of aromatherapy on stress using meta-analysis. Methods: Meta-analysis was done with 21 published studies, and data were analyzed with the SAS 9.1 program. Results: Fifty eight effect size was estimated with data from 21 published studies. Overall mean effect size (ES), and mean effect size of dependence variables according to the type of intervention and subject and according to the total amount of time spent in aromatherapy were estimated. Overall mean effect size of the effects of aromatherapy was .593, and the subjective stress (.983) was most effective in the physiological faculty, followed by mean effect size of cortisol (.648) and pulse (.40). On the other hand, mean effect size of systolic blood pressure (.490) was moderate, and that of diastolic blood pressure (.401) was not large. Mean effect size of elderly (.706) cancer patients was considerable(.337). There were significant differences depending on the subjects. With regards to the types of aromatherapy, the effect size of aroma massage combined with inhalation therapy was .590, and there were no significant differences between the intervention methods. With regards to the time of intervention, $20{\sim}30$ minutes spent in aromatherapy was .730, and there were no significant differences between the times of intervention. The relationship between the effect size and intervention frequency was r=.349 and showed significant difference. Conclusion: This result suggests that aromatherapy is an effective intervention to reduce stress for subjects. Nursing intervention protocol by using aromatherapy should be developed and applied in clinical and community settings. Further studies on the effects of aromatherapy on stress should be done by using meta-analysis.

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