• Title/Summary/Keyword: 에볼라 바이러스

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치사율 90% 공포의 에볼라 바이러스

  • 김양수
    • RED RIBBON
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    • s.5
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    • pp.20-20
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    • 1995
  • 바이러스의 이름은 유행지역에서 멀리 떨어지지 않은 자이르의 에볼라강에서 유래되었다. 현재까지는 영장류만이 병을 앓는 것으로 알려져 있으나, 바이러스 및 감염원은 아직도 모르고 있는데 다만 거미, 진드기, 박쥐, 원숭이 등이 숙주로서 의심되고 있을 뿐이다.

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Study on Laboratory Diagnosis of the Ebola Virus and Its Current Trends (에볼라 바이러스 진단법과 개발 동향에 관한 고찰 연구)

  • Jeong, Hye Seon;Kang, Yun-Jung
    • Korean Journal of Clinical Laboratory Science
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    • v.47 no.3
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    • pp.105-111
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    • 2015
  • In late December 2013, the Ebola virus emerged from West Africa. The outbreak started in Guinea and rapidly spread to Liberia and Sierra Leone. Initially, the virus is spread to the human population after contact with infected wildlife and then spread person-to-person through direct contact with body fluids such as blood, sweat, urine, semen, and breast milk. The Ebola virus infects endothelial cells, mononuclear phagocytes and hepatocytes. It causes massive damage to internal tissues and organs, such as blood vessels and the liver, and ultimately death. Most tests for the virus RNA rely on a technology called reverse-transcriptase polymerase chain reaction (RT-PCR). While this method is highly sensitive, it is also expensive, requiring skilled scientists, and delicate power supplies. The strip analytical technique (enzyme-linked immunosorbent assay or ELISA) detects antigens or antibodies to the Ebola virus. This test is cheap and does not require electricity or refrigeration. Despite ongoing efforts directed at experimental treatments and vaccine development, current medical work on the Ebola viral disease is largely limited to supportive therapy. Thus, rapid and reliable diagnoses of the Ebola virus are critically important for patient management, infections, prevention, and control measures.

A transmission distribution estimation for real time Ebola virus disease epidemic model (실시간 에볼라 바이러스 전염병 모형의 전염확률분포추정)

  • Choi, Ilsu;Rhee, Sung-Suk
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.1
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    • pp.161-168
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    • 2015
  • The epidemic is seemed to be extremely difficult for accurate predictions. The new models have been suggested that show quite different results. The basic reproductive number of epidemic for consequent time intervals are estimated based on stochastic processes. In this paper, we proposed a transmission distribution estimation for Ebola virus disease epidemic model. This estimation can be easier to obtain in real time which is useful for informing an appropriate public health response to the outbreak. Finally, we implement our proposed method with data from Guinea Ebola disease outbreak.

Ebola Hemorrhagic Fever Outbreaks: Diagnosis for Effective Epidemic Disease Management and Control (에볼라 출혈열 발병 : 효과적인 전염병 관리 및 통제를 위한 진단)

  • Kang, Boram;Kim, Hyojin;Macoy, Donah Mary;Kim, Min Gab
    • Microbiology and Biotechnology Letters
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    • v.45 no.2
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    • pp.87-92
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    • 2017
  • The first Ebola hemorrhagic fever outbreak occurred in the Democratic Republic of Congo and Sudan in 1976 and then emerged in West Africa in 2014 with a total of 27,741 cases and 11,284 deaths. The fever is caused by the Ebola virus, which belongs to the Filoviridae family and contains a ssRNA genome. The known subtypes of the virus are Bundibugyo ebolavirus, Reston ebolavirus, Sudan ebolavirus, $Ta\ddot{i}$ Forest ebolavirus, and Zaire ebolavirus. The Ebola outbreak was historically originated majorly from the East and Central African tropical belt. The current outbreaks in West Africa caused numerous deaths and spread fear in global society. In the absence of effective treatment strategies and any vaccine, accurate diagnosis is the most important contributing factor in the management and control of the epidemic disease. WHO (World Health Organization) has announced emergency guidance for the selection and use of Ebola in in vitro diagnostic assays. Numerous companies and research institutions have studied the various diagnosis methods and identified four WHO procurement approved as diagnosis kits: RealStar Ebolavirus Screen RT-PCR kit 1.0 (Altona), Liferiver-Ebola Virus (EBOV) Real time RT-PCR kit, Xpert Ebola Assay, and ReEBOV Antigen Rapid Test Kit. The efficiency of novel diagnostic kits such as Rapid Diagnosis Test (RDT) is currently being evaluated.

Text Mining Driven Content Analysis of Ebola on News Media and Scientific Publications (텍스트 마이닝을 이용한 매체별 에볼라 주제 분석 - 바이오 분야 연구논문과 뉴스 텍스트 데이터를 이용하여 -)

  • An, Juyoung;Ahn, Kyubin;Song, Min
    • Journal of the Korean Society for Library and Information Science
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    • v.50 no.2
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    • pp.289-307
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    • 2016
  • Infectious diseases such as Ebola virus disease become a social issue and draw public attention to be a major topic on news or research. As a result, there have been a lot of studies on infectious diseases using text-mining techniques. However, there is no research on content analysis of two media channels that have distinct characteristics. Accordingly, in this study, we conduct topic analysis between news (representing a social perspective) and academic research paper (representing perspectives of bio-professionals). As text-mining techniques, topic modeling is applied to extract various topics according to the materials, and the word co-occurrence map based on selected bio entities is used to compare the perspectives of the materials specifically. For network analysis, topic map is built by using Gephi. Aforementioned approaches uncovered the difference of topics between two materials and the characteristics of the two materials. In terms of the word co-occurrence map, however, most of entities are shared in both materials. These results indicate that there are differences and commonalties between social and academic materials.

Systemic and oral manifestations of Ebola virus disease (에볼라 바이러스 감염의 전신 및 구강내 소견)

  • Kim, Min Ji;Kim, Hui Young;Kim, Soung Min;Myoung, Hoon;Lee, Jong Ho
    • The Journal of the Korean dental association
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    • v.54 no.1
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    • pp.67-83
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    • 2016
  • Ebola virus disease is a lethal viral hemorrhagic fever that has been boiling in sub-Saharan Africa since 1970s. Last year, The Ebola virus epidemic that has spread not only mainly in West Africa, but also in locals such as USA, Europe and the Antipodes via infected travelers, was brought up. Human-to-human transmission of Ebola virus disease is known only through direct contact with the blood, secretions, tissues or other bodily fluids, including saliva. Although there has not been reported infection cases in the dental healthcare settings, the fact that the infection of the Ebola virus may be made from human secretions such as saliva suggests that there is a high risk of infection for the Ebola virus of dental healthcare workers. Therefore, it is important dental healthcare workers to identify infection-suspected patients through the oral findings for infection prevention. This article will review the oral signs and symptoms of Ebola virus disease and discuss the pathogenesis, treatment and prevention. Furthermore, Infection control guidelines for oral healthcare workers are also proposed.

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Reasonable Solutions for Legal Disputes and Regulations on Epidemics (감염병 관련 법적 분쟁과 규제에 관한 합리적 해결방안)

  • Lee, Kyunghwan;Kim, Taehwan;Kim, Mannoh;Han, Sunwoo
    • Journal of the Society of Disaster Information
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    • v.12 no.2
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    • pp.150-166
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    • 2016
  • In the aftermath of a recent outbreak of Middle East respiratory syndrome (MERS), legal matters on the spread of epidemics have emerged as major social issues in Korea, with the awareness that rampant contagious diseases are disasters in society. Problems arose over damages arising from patients who contract infectious diseases, compensation for people under quarantine and for a partial, or entire, shutdown of hospitals, and information disclosure on infectious diseases. As epidemic-linked problems have never been socially disputed in Korea, the relevant legal issues appear to be studied comparatively less than other areas. As interests are heightened over legal issues on infectious illnesses amid the MERS scare, in-depth, further research on such legal issues should be conducted in an utmost effort to prevent and make preparations for epidemics which potentially become a social disaster, such as new Hong Kong flu, Ebola virus and Zika virus.