• Journal of Korean Tunnelling and Underground Space Association
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• v.24 no.6
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• pp.465-481
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• 2022

Rock grouting is important to improve the waterproof efficiency and mechanical strength of rock medium with joint for utilizing the underground rock space such as tunnel. The grouting materials typically has been used the cement materials, which represent Bingham fluid model. This model can express the relationship of viscosity and yield strength. In addition, it is dependent with elapsed time. The grouting injection performance can be deteriorated with an increase of viscosity and yield strength in the grouting process if the time dependence is ignored. Therefore, in this study, the characteristics of viscosity and yield strength were investigated according to water-cement ratio and time dependence in the laboratory test. Numerical simulation was carried out to investigate the grouting performance according to the time dependence of characteristics in terms of the viscosity model. Given the results, the grouting injected distance and cumulative grout volume were significantly decreased when the time dependence of grouting material was considered. This study, considering the characteristics according to the time dependence of viscosity and yield strength, will be meaningful to the design of grouting injection in field applications.

• The Journal of Korean Academy of Prosthodontics
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• v.59 no.4
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• pp.478-486
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• 2021

This report demonstrates a method of generating a chair-side and computer-aided template for implant surgery based on the Top-Down and restoration-driven concept. Compared to the traditional CAD-CAM process which requires multiple steps to be taken between dental clinic and laboratory, this alternative procedure, VARO guide system (VARO Guide, CAD, Pre-Guide, VARO-mill, NeoBiotech, Seoul, South Korea) enables accurate and patient-friendly implant surgery as well as immediate provisional restoration in a single visit. First, bite-registration at centric jaw relation and CBCT were taken using the Pre-Guide. The CBCT data was then reorganized directly through the chair-side CAD, and we could determine the most appropriate 3-dimensional position of implant. The STL file was extracted and put into the chair-side CAM (VARO-mill) to fabricate a VARO. This surgical guide allowed the implants to be accurately positioned into the planned sites within an hour.

• Journal of the Korea institute for structural maintenance and inspection
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• v.25 no.6
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• pp.12-18
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• 2021

The purpose of this study is to effectively mitigate the bending displacement that occurs in the bridge due to forced vibration. We developed CTMD (Combine Tuned Mass Damper) that combines the relationship between spring and mass to control the bending behavior of simple beams. The experiment was conducted to confirm the control effect according to the change in the mass ratio of the developed CTMD. The developed CTMD is designed and manufactured so that the mass ratio can be adjusted according to the characteristics of the bridge. The maximum load of the spring applied to CTMD was fixed at 33.15 N. In order to evaluate the performance of the developed CTMD, a simple beam composed of hinges and rollers as boundary conditions was fabricated. In the experimental method, a CTMD was installed in the center of a simple beam and the deflection displacement according to the mass ratio was measured. The shaking condition was shaken at 3 Hz to induce the maximum bending behavior of the simple beam. As a result of the experiment, it was confirmed that when the optimal mass ratio was 2.1, the damping rate of the bending behavior displacement was about 71.2 %, indicating the best control effect.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.32 no.1
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• pp.17-27
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• 2019

In this paper, we study the applicability of Tuned Mass Damper(TMD) to improve seismic performance of piping system under earthquake loading. For this purpose, a mode analysis of the target pipeline is performed, and TMD installation locations are selected as important modes with relatively large mass participation ratio in each direction. In order to design the TMD at selected positions, each corresponding mode is replaced with a SDOF damped model, and accordingly the corresponding pipeline is converted into a 2-DOF system by considering the TMD as a SDOF damped model. Then, optimal design values of the TMD, which can minimize the dynamic amplification factor of the transformed 2-DOF system, are derived through GA optimization method. The proposed TMD design values are applied to the pipeline numerical model to analyze seismic performance with and without TMD installation. As a result of numerical analyses, it is confirmed that the directional acceleration responses, the maximum normal stresses and directional reaction forces of the pipeline system are reduced, quite a lot. The results of this study are expected to be used as basic information with respect to the improvement of the seismic performance of the piping system in the future.

• Journal of Life Science
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• v.28 no.12
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• pp.1545-1553
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• 2018

The International Society of Rare Sugars (ISRS) defines rare sugars as monosaccharides and their derivatives that rarely occur in nature. Rare sugars have recently received much attention because of their many uses including low-calorie sweeteners, bulking agents, and antioxidants, and their various applications including as immunosuppressants in allogeneic rat liver transplantation, as potential inhibitors of various glycosidases and microbial growth, in ischemia-reperfusion injury repair in the rat liver, and in segmented neutrophil production without detrimental clinical effects. Because they rarely exist in nature, the production of rare sugars has been regarded as one of the most important research areas and, generally, they are produced by chemical synthesis. However, the production of rare sugars by bioconversion using enzymes from microorganisms has been receiving increased attention as an environmentally friendly alternative production method. In particular, D-allulose, D-allose, and D-tagatose are of interest as low-calorie sweeteners in various industries. To date, D-tagatose 3-epimerase, D-psicose 3-epimerase, and D-allulose 3-epimerase have been reported as D-allulose bioconversion enzymes, and L-rhamnose isomerase, Galactose 6-phosphate isomerase, and Ribose 5-phosphate isomerase have been identified as D-allose production enzymes. Elsewhere, D-tagatose has been produced by L-arabinose isomerase from various microorganisms. In this study, we report the production of D-allulose, D-allose, and D-tagatose by microorganism enzymes.

• 한국노년학
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• v.38 no.3
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• pp.593-605
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• 2018

This study examines factors that influence older drivers to consider stopping driving in advance and whose advice plays an important role in the driving cessation decision. Data came from a nationally representative cross-sectional survey of community-dwelling older adults (N=2,076). About two thirds reported that they have considered stopping driving (62.8%) and they preferred to decide by themselves (66.0%). Logistic regression results showed that women and residents in urban areas were twice as likely to consider voluntary driving cessation compared to their counterparts. Each one year increase in age contributed to the probability that respondents would consider driving cessation by five percent. Those with greater difficulties in ADLs due to chronic illnesses were also more likely to consider driving cessation. No sociodemographic and health factors were related to whether older drivers preferred to decide by themselves or listen to others. These results imply that policies to promote self-motivation to stop driving among older drivers would be effective. Furthermore, they suggest it could be important to help older drivers plan their driving cessation in advance while still at a young-old age, and that more attention needs to be paid to men and those living in rural areas among older drivers.

• Journal of the Korean Applied Science and Technology
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• v.36 no.2
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• pp.488-497
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• 2019

The purpose of this study was to confirmed anti-inflammatory effect the apple Induced by mutants with ${\gamma}-Ray$ extract. Cell viability was assessed by MTT assay using RAW 264.7 cells. The extracts measured through changes in the levels of reactive oxygen species (ROS), nitric oxide (NO), inflammatory cytokines, NF-kB, and COX-2 on LPS-induced RAW 264.7 cells. All test results were analyzed by ELISA reader, Luminex and RT-PCR. In result, the extracts was not toxic below in 25 ug/ml, and extracts was inhibited the productions nitric oxide, ROS, cytokines (IL-1b, IL-6, TNF-a), NF-kB and COX-2 in LPS-induced RAW 264.7 cells. Also, the expression levels were decreased on mRNA of $NF-{\kappa}B$ and COX-2. In other words, Perilla frutescens var. crispa Induced by mutants with ${\gamma}-Ray$ extracts showed significant anti-inflammatory effect. These results may be developed as a raw material for new health food and therapeutics to ease the related to the above mediators.

• Korean Journal of Environmental Agriculture
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• v.38 no.2
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• pp.83-88
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• 2019

BACKGROUND: In recent years, studies on microplastics have focused on their decomposition in the ocean. However, no studies have been reported on the interaction between microplastics and metal ions in aqueous solutions. Therefore, this study was conducted to evaluate the adsorption capacity of cadmium(Cd) by polypropylene (PP) in aqueous solution. METHODS AND RESULTS: Cadmium adsorption characteristics of PP in aqueous solution were evaluated through various conditions including initial Cd concentration(1.25-25 mg/L), contact time(0.5-24 h), initial pH(2-6) and temperature($20-50^{\circ}C$). Cadmium adsorption fit on PP was well described by Freundlich isotherm model with adsorption capacity(K) of 0.028. The adsorption amount of Cd by PP increased with increasing contact time, indicating that adsorption of PP by Cd was dominantly influenced by contact time. Especially, the removal efficiency of Cd by PP was highest at high temperature. However, the surface functional groups of PP before and after adsorption of Cd were similar, suggesting that adsorption of Cd by PP is not related to surface functional groups. CONCLUSION: Our study suggests that PP affects the behavior of Cd in aqueous solution. However, in order to clarify the specific relationship between microplastics and metal ions, mechanism research should be carried out.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.5
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• pp.477-484
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• 2019

As the residence time in the vehicle increases, the passenger desires a pleasant and stable riding environment in addition to the high driving performance of the vehicle. The windshield defrosting performance is one of the performance requirements that is essential for driver's safe driving. In order to improve the defrosting performance of the windshield of a vehicle, relevant elements such as the shape of the defrost nozzle should be appropriately designed. In this paper, CFD based numerical analysis is conducted to improve defrost performance of small electric vehicles. The defrost performance analysis was performed by changing the angle of the defrost nozzle and the guide vane that spray hot air to the windshield of the vehicle. Numerical simulation results show that the defrosting performance is best when the defrost nozzle angle is $70^{\circ}$ and the guide vane installation angle is $60^{\circ}$. Based on the analytical results, the defrosting experiment was performed by fabricating the defrost nozzle and the guide vane. As a result of the experiment, it is confirmed that the frost of windshield is removed by 80% within 20 minutes, and it is judged that the defrost performance satisfying the FVMSS 103 specification is secured.

• Korean Journal of Plant Resources
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• v.32 no.4
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• pp.282-289
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• 2019

Gastritis is an inflammatory disease involving the stomach and is caused by several factors, including stress, non-steroidal anti-inflammatory drugs such as aspirin, liquor, and Helicobacter pylori. In Korea, Leonurus japonicus Houttuyn (LJW) has been used as traditional medicine for vaginal bleeding, hematuria, and bruise. Previous studies have reported that LJW exhibited hepatoprotective, cardioprotective, and anti-hyperlipidemic effect. However, the effect of the water extract of LJW on gastritis was not elucidated. Thus, we evaluated the anti-gastric effect and genotoxicity of LJW. LJW effectively prevented the degeneration of surface mucous cells and glandular epithelial cells and vascular congestion induced by HCl/EtOH. Micronucleus assay indicated that the rate of micronucleated polychromatic erythrocytes/polychromatic erythrocytes was not significantly different compared that of the control. Further experiments are required to determine the role of LJW in the gastric injury process such as cyclooxygenase signaling pathway and the secretion of mucus in the stomach.