• Title/Summary/Keyword: 안전기능분석

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Surgical Treatment of Arrhythmias Associated with Congenital Heart Disease (선천성 심장 기형에 동반된 부정맥에 대한 수술적 치료)

  • Hwang, Ui-Dong;Im, Yu-Mi;Park, Jeong-Jin;Seo, Dong-Man;Lee, Jae-Won;Yun, Tae-Jin
    • Journal of Chest Surgery
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    • v.40 no.12
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    • pp.811-816
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    • 2007
  • Background: We analyzed our experience of arrhythmia surgery in patients with congenital heart disease. Material and Method: A retrospective review was performed on 43 consecutive patients with congenital heart disease, who underwent arrhythmia surgery between June 1998 and June 2006. Result: The median age at surgery was 52 years ($4{\sim}75$ years). The most frequent cardiac anomaly was an atrial septal defect (23/43, 53.5%). The types of arrhythmias were atrial flutter-fibrillation, intermittent non-sustainable ventricular tachycardia and others in 37, 2 and 4, respectively. Arrhythmia surgery consisted of a bi-atrial maze operation in 18 patients (modified cox maze III procedure in 5 patients, and a right side maze plus pulmonary vein cryo-isolation in 13), right side maze operation in 18 patients, cavo-tricuspid isthmus cryoablation for benign atrial flutter in 4 patients, right ventricular endocardial cryoablation in 2 patients and extranodal cryoablation for atrioventricular node re-entry tachycardia in 1 patient. The median follow-up was 23.8 months ($1{\sim}95.2$ months). There was no early mortality, and one late non-cardiac related death. The overall rates of restored sinus rhythm before discharge and $3{\sim}6$ months after surgery were 79% and 81%, respectively (bi-atrial maze group: 72% and 83%, right-side maze group: 77%, 77%). Conclusion: Arrhythmias associated with congenital heart disease can be safely treated surgically with an excellent intermediate-term outcome.

Effects of Membrane-filtered Powder of Sunmul on the Quality Characteristics of Noodles (막분리한 순물의 농축분말 첨가가 국수의 품질에 미치는 영향)

  • Chung, Hai-Jung;Choi, Min-Hee;Kim, Woo-Jung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.2
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    • pp.199-204
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    • 2006
  • This study was conducted to investigate the quality characteristics of noodles prepared with the addition of nanofiltered (NF) powder of sunmul. Noodles were prepared with different levels $(0\%,\;1.5\%,\;3\%\;and\;5\%,\;w/w)$ of NF powder and physico-chemical properties were examined. Results of rapid visco analyzer showed that peak, trough, final viscosity and set back decreased as the NF powder level increased. The weight and volume of cooked noodles increased with the addition of NF powder. Turbidity of soup also increased as the amount of NF powder increased, indicating higher cooking loss. The color of wet and cooked noodles became greenish yellow as the NF powder level increased. Hardness, springiness, gumminess and brittleness of cooked noodles decreased with the increasing amount of NF powder. Results of sensory evaluation showed that noodles prepared with up to $3\%$ addition of NF powder was considered to be as acceptable as noodles prepared without NF powder.

Significance of p53 as a Prognostic Factor in Non-Small Cell Lung Carcinoma (비소세포 폐암종에 있어서 p53의 예후 인자로서의 의의)

  • 이상호;한정호;김관민;김진국;심영목;장인석
    • Journal of Chest Surgery
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    • v.37 no.8
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    • pp.672-683
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    • 2004
  • Background: The treatment results of the advanced lung carcinoma is not satisfactory with the present therapeutic modalities: surgical resection, anti-cancer chemotherapy, and radiotherapy or combination therapy. To predict the prognosis of the non-small-cell lung carcinoma, TNM classification has been was as the basic categorization; however, it has been not satisfactory. It is necessary to consider the causes and the prognosis of the lung carcinoma from another points of view rather the conventional methods. We intended to find out the relationship between the major apoptotic factor, p53 gene and the prognosis of the patient with lung carcinoma. Material and Method: Three hundreds and fifty-nine patients with lung carcinoma who underwent surgery were analysed. We observed p53 protein accumulated in the cellular nuclei. The p53 protein was detected by immuno-histo-chemical method. We collected information of the patient retrospectively. Result: p53 protein densities were observed in 40% in average as a whole. The protein density was 44 percent in man, 25 percent in woman, 49 percent in the squamous cell carcinoma, and 38 percent in the adenocarcinoma. There were significant correlations between the p53 protein density and the mortality in the squamous cell carcinoma (p=0.025), follow-up duration in TNM stage I group (p=0.010), and follow-up duration in the lobectomy patient group (p=0.043), and tumor cell differentiation (p=0.009). p53 protein densities were significantly different between the lobectomy and the pneumonectomy group (p=0.044). Conclusion: The authors found that p53 protein had some correlations with the prognosis of the lung cancer partially in some factors. We suggest the p53 protein density could be used as a marker of prognosis in the non-small-cell lung carcinoma.

Australian Case Study in Regulatory Techniques to the Security Industry Reform and Policy Implications (호주 민간경비산업 고품질 규제수단 검토 및 시사점)

  • Kim, Dae-Woon
    • Korean Security Journal
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    • no.47
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    • pp.7-36
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    • 2016
  • The security providers industry, often referred to as an industry with unconfined growth ceiling, has entered a remarkable mass-growth phase since the 1980. In the modern era, private-sector security increasingly cover functions relating to general security awareness (including counter-terrorism) in partnership with State bodies, and the scale of operations continue to accelerate, relative to the expanding roles. In the era of pluralisation of policing, there has been widening efforts pursued to develop a range of regulatory strategies internationally in order to manage such growth and development. To date, in South Korea, a diverse set of industry review studies have been conducted. However, the analyses have been conventionally confined to North America, Britain, Germany and Japan, while developments in other world regions remain unassessed. This article is intended to inform the drivers and determinants of regulatory reforms in Australia, and examine the effectiveness of the main pillars of licensing innovations. Over the past decades, the Australian regime has undergone a wave of reforms in response to emerging issues, and in recognition of the industry as a 'public good' due to underpopulation density and the resulting security challenges. The focus of review in this study was on providing a detailed review of the regulatory approach taken by Australia that has expanded police-private security co-operation since the 1980s. The emphasis was on examining the core pillars of risk management strategies and oversight practices progressed to date and evaluating areas of possible improvement in regulation relative to South Korea. Overall, this study has identified three key features of Australian regime: (1) close checks on questionable close associates (including fingerprinting), (2) power of inspection and seizure without search warrant, (3) the 'three strikes' scheme. The rise of the private security presence in day-to-day policing operations means that industry warrant some intervening government-sponsored initiative. The overall lessons learnt from the Australian case was taken into account in determining the following checks and balances that would provide the ideal setting for the best-practice arrangement: (1) regulatory measure should be evaluated against a set of well-defined indicators, such as the merits of different enforcement tools for each given risk, (2) information about regulatory impacts should be analysed by a specialist research institute, (3) regulators should be innovative in applying a range of strategies available to them by employing a mixture of compliance promotional strategies, and adjust the mix as required.

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Characteristics of Marine Algal Communities in the Spring at Gijang-gun, Busan (부산시 기장군 연안의 춘계 해조 군집 특성)

  • Jung, Seung-Wook;Choi, Chang-Geun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.2
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    • pp.175-185
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    • 2020
  • Quantitative and qualitative surveys were conducted during scuba diving activity between May 2017 and June 2017 in order to analyze spring marine algal community structure at Gijang-gun, Busan. A total of 121 species including 13 (10.7 %) Chlorophyta, 18 (14.9 %) Phaeophyta, and 90 (74.4 %) Rhodophyta were identified. The species count in the subtidal zone (110 species) was twice as high as in the intertidal zone (56 species). In terms of regions, 88,76, and 75 species were found in Mundong, Gongsu, and Daebyeon, respectively. Mean biomass for the whole study area was 1,501.5 g·m-2, higher for the subtidal zone (1,869.4 g·m-2) than for the intertidal zone (1,133.5 g·m-2). Mean biomass by region values were 2,234.0 g·m-2, 1,228.1 g·m-2, and 1,044.4 g·m-2 for Mundong, Gongsu, and Daebyeon, respectively. Ulva australis, Sargassum thunbergii, and Corallina pilulifera had high biomass in the intertidal zone, while Sargassum macrocarpum, Undaria pinnatifida, and Phycodrys fimbriata had high biomass in the subtidal zone. The composition ratio of marine algal functional forms suggests that the entire study area had 'Low' status, and all sites fell within 'Low' to 'Moderate' status. Results indicate that opportunistic species are widely distributed throughout the Gijang-gun coast, hence potential effects of disturbance and environmental pollution should be considered. Seaweed farming in particular - a major activity along the Gijang-gun coast -, together with effects of other anthropogenic activities such as national fishing port development and the coastal improvement project, could have long-term effects on marine algal communities. Therefore, long-term monitoring and management plans for marine algal communities will be required.

Risk Management and Strategies in Airport Security Check (공항 보안검색에 있어서의 위험관리와 대응과제)

  • Kim, Jae-Woon
    • Korean Security Journal
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    • no.34
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    • pp.89-113
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    • 2013
  • Travel by airplane using airport in globalized modern society is familiar to our life but such airport can be a target of terrorists who would threaten our safety. However, aviation terrorism which is represented by 9.11 terror gives horror beyond our imagination to modern people. Since the first airplane hijacking in Peru in 1931 happened, security organization in each nation has taken various prevention measures to block aviation terrorism. The most realistic measures to prevent aviation terrorism would be security check activity to control approach of terrorist that passengers on airplane and cargos are checked to find out dangerous article like explosive etc. But security check activity in Korea shifted to security check activity focused on private security for efficiency of airport operation differently from security check activity in advanced countries where public interests is strengthened according to risk of terror after 9.11 system. That is, since Incheon airport opened in March 2001, security check system focused on the police was changed. Now Incheon international airport Corporation instructs and supervises security check job and private security personnel are in charge of actual security check activity. But this check system has limitation in blocking terror activity by terrorists which is systematized and intelligent as time passes due to deteriorated job satisfaction of private security personnel and confusing supervising system. Accordingly, it is suggested to introduce risk management skill which is one of management strategy of private corporation for security check activity to prevent terror activity. With this skill, risk factors of aviation terror are identified and analyzed regularly, and each process such as setting of priority, activity to reduce risk, and assessment of security is carried out. And it would be necessary to do efforts, for example, to properly change level of security check according to threat of terror such as to place policeman at airport security in case threat of terror is severe. On the other hand, it is necessary to establish national police organization for good communication of security check activity in field and supervising function, which can encourage systematization and specialization of aviation security job.

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Effect of Chestnut on lipid Metabolism and Antithrombotic Capacity in Rats (랫드에서 밤의 과육 및 내피가 지방대사 및 항혈전능에 미치는 영향)

  • Kim, So-Jung;Kim, Mi-Hwan;Kim, Jin;Kim, Hyeong-Jin;Kim, Soo-Hyun;Lee, Seung-Ho;Park, Young-Seok;Park, Byung-Kwon;Kim, Byeong-Soo;Kim, Sang-Ki;Choi, Chang-Sun;Ryu, Gi-Hyung;Jung, Ji-Youn
    • Journal of Food Hygiene and Safety
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    • v.24 no.1
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    • pp.69-77
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    • 2009
  • This study was performed to investigate the effect of dried powder of chestnut on lipid metabolism, anti-thrombotic effect in rats. Thirty 5-week-old male Sprague Dawley (SD) rats were randomly allocated into five groups and used for experiment. We examined the lipid metabolism and antithrombotic capacity of SD rats administered for 5 weeks with 0.16 g/kg, 0.5 g/kg chestnut flesh powder and 0.16 g/kg, 0.5 g/kg chestnut inner shell and flesh powder mixture, respectively. Food intake, body weight gain and food efficiency ratio were also checked. The levels of serum triglyceride and tree fatty acid were not statistically significant between the all experimental groups. However, the antithrombotic capacity and total lipid levels of the treatment groups were significantly lower than those of the negative control group. These results suggest that the supplementation of chestnut on diet lower the total lipid level in SD rats.

Analyzing the Potential of legally protected Trees to Create Community Spaces in Rural Areas - Focusing on the Case of Gimchon City - (농촌마을의 커뮤니티 공간 조성을 위한 보호수 잠재력 분석 - 김천시를 중심으로 -)

  • Jung, Tae-Yeol;Kim, Eun-Jin
    • Journal of the Korean Institute of Landscape Architecture
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    • v.45 no.1
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    • pp.73-81
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    • 2017
  • During the 1990s, policy was put in place to create resting spaces in rural areas. This policy was associated with a government project to improve the rural residence environment and it attracted attention to outdoor spaces in rural areas. Many communities have gradually disappeared in rural areas but previous studies suggested that legally protected trees might provide resting and cultural spaces in a given rural community. The rural residential environment can be improved by legally protected trees and by doing so, these resources may then help to sustain many rural communities. Therefore, the creation of resting spaces or mini-parks created around trees that are protected by in rural communities should be considered. The value of trees that are protected by law can differ depending on the status of the trees or the surroundings. Nevertheless, there has not been systemic research regarding legally-protected trees in terms of rural communities. This study aims at evaluating the potential of these trees and at analyzing how these trees can be useful in the creation of community spaces in rural areas. The findings can be helpful in providing foundation data for creating these types of community spaces. Forty legally protected trees in Gimchon City were selected for this study. Nine items were used to evaluate the potential of the trees for creating community spaces. These items could be classified into five factors including accessibility, relation to public facilities, environment and safety, symbolism, and ease for creating community spaces. The potential of the legally protected trees was evaluated by 5-point Likert Scales in a given item. The overall potential was evaluated by the sum of individual item scores. Specifically, trees with over 20 points (max. 25 points) could be considered high potential. According to the empirical findings, the portion of legally protected trees with high potential is five percent (No.7 and No.12 trees). Therefore, the priority is to protect or use the trees for the creation of community spaces that can help make a better residential environment for rural communities.

The Optimal Operation on Auxiliary Spillway to Minimize the Flood Damage in Downstream River with Various Outflow Conditions (하류하천의 영향 최소화를 위한 보조 여수로 최적 활용방안 검토)

  • Yoo, Hyung Ju;Joo, Sung Sik;Kwon, Beom Jae;Lee, Seung Oh
    • Journal of Korean Society of Disaster and Security
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    • v.14 no.2
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    • pp.61-75
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    • 2021
  • Recently, as the occurrence frequency of sudden floods due to climate change increased and the aging of the existing spillway, it is necessary to establish a plan to utilize an auxiliary spillway to minimize the flood damage of downstream rivers. Most studies have been conducted on the review of flow characteristics according to the operation of auxiliary spillway through the hydraulic experiments and numerical modeling. However, the studies on examination of flood damage in the downstream rivers and the stability of the revetment according to the operation of the auxiliary spillway were relatively insufficient in the literature. In this study, the stability of the revetment on the downstream river according to the outflow conditions of the existing and auxiliary spillway was examined by using 3D numerical model, FLOW-3D. The velocity, water surface elevation and shear stress results of FLOW-3D were compared with the permissible velocity and shear stress of design criteria. It was assumed the sluice gate was fully opened. As a result of numerical simulations of various auxiliary spillway operations during flood season, the single operation of the auxiliary spillway showed the reduction effect of maximum velocity and the water surface elevation compared with the single operation of the existing spillway. The stability of the revetment on downstream was satisfied under the condition of outflow less than 45% of the design flood discharge. However, the potential overtopping damage was confirmed in the case of exceeding the 45% of the design flood discharge. Therefore, the simultaneous operation with the existing spillway was important to ensure the stability on design flood discharge condition. As a result of examining the allocation ratio and the total allowable outflow, the reduction effect of maximum velocity was confirmed on the condition, where the amount of outflow on auxiliary spillway was more than that on existing spillway. It is because the flow of downstream rivers was concentrated in the center due to the outflow of existing spillway. The permissible velocity and shear stress were satisfied under the condition of less than 77% of the design flood discharge with simultaneous operation. It was found that the flood damage of downstream rivers can be minimized by setting the amount allocated to the auxiliary spillway to be larger than the amount allocated to the existing spillway for the total outflow with simultaneous operation condition. However, this study only reviewed the flow characteristics around the revetment according to the outflow of spillway under the full opening of the sluice gate condition. Therefore, the various sluice opening conditions and outflow scenarios will be asked to derive more efficient utilization of the auxiliary spillway in th future.

Anti-obesogenic Effect of Brassica juncea Extract on Bisphenol-A Induced Adipogenesis of 3T3-L1 Cells (비스페놀 A (Bisphenol-A)로 유도된 지방세포 분화에 미치는 갓 추출물의 항오비소겐 효과)

  • Lee, Se-jeong;Na, Uoon-Joo;Choi, Sun-Il;Han, Xionggao;Men, Xiao;Lee, Youn Hwan;Kim, Hyun Duk;Kim, Yoon Jung;Lee, Ok-Hwan
    • Journal of Food Hygiene and Safety
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    • v.36 no.6
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    • pp.528-536
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    • 2021
  • The purpose of the study was to investigate the content of sinigrin, an index component, in Brassica juncea extract and to evaluate the differentiation of lipocytes, inhibition of production of reactive oxygen species (ROS) and reduction of protein production by lipogenic factors (PPARγ, C/EBPα, aP2) in the processing of Brassica juncea extract and sinigrin in 3T3-L1 preadipocytes which induces Bisphenol A (BPA), an endocrine disrupting environmental hormone. From the investigation, the content of sinigrin in Brassica juncea extract, measured by HPLC, is found to be 21.27±0.2 mg/g. The XTT assay result on BPA-derived 3T3-L1 adipocytes shows there is no cytotoxicity found from 180 µM of sinigrin and 300 ㎍/mL of Brassica juncea extract. Moreover, both intracellular lipid accumulation and ROS production during differentiation of lipocyte are significantly reduced in cells processed with Brassica juncea extract and sinigrin. Lastly, it was also found that the production of transcription factors of lipocyte differentiation, PPARγ, C/EBPα and aP2, were found to be suppressed by the application of Brassica juncea extract and sinigrin. Such results reveals that Brassica juncea is effective in not only suppressing lipid accumulation in the environmental hormone bisphenol A-derived lipocyte, but also in reducing the ROS. The sinigrin-containing Brassica juncea is highly expected to be used in natural functional supplements that prevents the lipid metabolism disorders caused by BPA. There are necessities for additional clinical research and follow-up studies on the in vivo model to verify the relevant mechanisms.