• Title/Summary/Keyword: 심혈관

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Automatic Extraction of Ascending Aorta and Ostium in Cardiac CT Angiography Images (심장 CT 혈관 조영 영상에서 대동맥 및 심문 자동 검출)

  • Kim, Hye-Ryun;Kang, Mi-Sun;Kim, Myoung-Hee
    • Journal of the Korea Computer Graphics Society
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    • v.23 no.1
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    • pp.49-55
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    • 2017
  • Computed tomographic angiography (CTA) is widely used in the diagnosis and treatment of coronary artery disease because it shows not only the whole anatomical structure of the cardiovascular three-dimensionally but also provides information on the lesion and type of plaque. However, due to the large size of the image, there is a limitation in manually extracting coronary arteries, and related researches are performed to automatically extract coronary arteries accurately. As the coronary artery originate from the ascending aorta, the ascending aorta and ostium should be detected to extract the coronary tree accurately. In this paper, we propose an automatic segmentation for the ostium as a starting structure of coronary artery in CTA. First, the region of the ascending aorta is initially detected by using Hough circle transform based on the relative position and size of the ascending aorta. Second, the volume of interest is defined to reduce the search range based on the initial area. Third, the refined ascending aorta is segmented by using a two-dimensional geodesic active contour. Finally, the two ostia are detected within the region of the refined ascending aorta. For the evaluation of our method, we measured the Euclidean distance between the result and the ground truths annotated manually by medical experts in 20 CTA images. The experimental results showed that the ostia were accurately detected.

Intervention Effect on Health Efficacy and Knowledge in Cardiovascular Health Promotion Behaviors in Children (초등학생 대상의 건강 효능감과 지식을 중심으로 한 심혈관 건강증진 중재 효과)

  • Tak, Young-Ran;Yun, E-Hwa
    • Korean Journal of Health Education and Promotion
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    • v.26 no.5
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    • pp.97-113
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    • 2009
  • Objectives: This study was conducted to identify the intervention effects on health efficacy and health knowledge related to health behaviors for improving cardiovascular health in elementary school children. Methods: A repeated measure, pre-post-test design was used to identify the intervention effect on health efficacy and health knowledge among 5th grade school children. Intervention consisted of a curriculum classroom intervention and parent intervention. Health efficacy, health knowledge, and perceived parental monitoring were measured for testing intervention effect. A sample of 219 participants completed a baseline pre-test and two tests during intervention and after intervention from March to July 2004. Results: Mental health efficacy improved significantly from baseline test to the test after intervention (F = 32.88, p < 0.0001). Physical health efficacy also significantly increased during intervention (F = 50.51, p < 0.0001), but did not significantly change after parent intervention. Health knowledge increased significantly from baseline test to the test after education (F =10.23, p < 0.0001), but decreased after parent intervention. Perceived parental monitoring had a significant impact on mental health efficacy and physical health efficacy. Conclusion: The findings support school-based cardiovascular health promotion intervention as effective in improving health efficacy and health knowledge. Parental influence should also be considered to maintain improved health efficacy and health knowledge by thinking process in the intervention for elementary school children.

Relationship of Riboflavin and Niacin with Cardiovascular Disease (심혈관 질환과 리보플라빈 및 나이아신과의 상관성 연구)

  • Ahn, Ji Yeong;Kim, In Sik;Lee, Ji-Sook
    • Korean Journal of Clinical Laboratory Science
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    • v.51 no.4
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    • pp.484-494
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    • 2019
  • Cardiovascular disease is caused by different factors. These factors include innateness factors such as aging, biological factors such as high blood pressure, and environmental factors such as stress. This study examined the factors associated with cardiovascular disease and the ways to reduce its prevalence by analyzing the data within the Korean National Health and Nutrition Examination Reports from 2013 to 2017, and particularly the survey and examination data for people over 50 years old. The study population was divided into two groups: members of the first group consumed riboflavin and niacin at the recommended rate while those in the second group did not. Riboflavin intake was correlated with hypertension, hyperglycemia, and a low HDL-cholesterol level, whereas niacin intake was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level. The combination of niacin and riboflavin intakes was correlated with hypertension, hyperglycemia, waist size, and a low HDL-cholesterol level (P<0.05). The combined intake of the recommended levels of riboflavin and niacin reduced the average physiological factor abnormality rate to 80%. Taken together, the beneficial effects of riboflavin and niacin can reduce the prevalence of cardiovascular disease.

Amiloride-sensitive $Na^+$ Channels Are Not Involved in the Cardiovascular Responses to Increased $Na^+$ Concentration in Cerebrospinal Fluid (뇌척수액내 $Na^+$ 농도 증가에 의한 심혈관 반응과 Amiloride 민감성 $Na^+$ Channel과의 관계)

  • Kook, Hyun;Kim, Jae-Ha;Baek, Yung-Hong
    • The Korean Journal of Pharmacology
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    • v.30 no.3
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    • pp.313-319
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    • 1994
  • This study was undertaken to investigate the relationship between the $Na^+$ channels of the cardiovascular regulation center and the responses to increased $Na^+$ concentration in the cerebrospinal fluid (CSF), by observing the effects of icv administration of the agents affecting $Na^+$ transport. Icv infusion of $200\;{\mu}l$ of 1 M NaCl produced hypertension and bradycardia in the urethane-anesthetized rabbit, and the bradycardia was inhibited and reversed to tachycardia by vagotomy. Amiloride, a $Na^+$ transport inhibitor, produced hypertension and bradycardia, which were not altered by vagotomy, and it did not affect the NaCl-induced responses. Benzamil, a derivative of amiloride with higher specificity, neither produced any cardiovascular effects by itself, nor affected the NaCl-induced responses. In vagotomized rabbits, icv amiloride reversed the NaCl-induced tachycardia to a bradycardia, but the bradycardiac effect was not altered by pretreating with NaCl. This study showed that although amiloride and benzamil slightly differ in their cardiovascular action, neither of them did affect the NaCl-induced responses. We suggest that the $Na^+$ channels which are sensitive to amiloride or benzamil in the cardiovascular regulation center are not involved in the NaCl-induced response.

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