• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.142-142
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• 2001

목적： 관상동맥의 이상으로 인해 여러 가지 심장 관련 질환이 발병하기 때문에 관상동맥을 관찰할 수 있는 영상기법의 필요성이 늘어남은 물론 세계적으로 Cardiac 영상 기법 개발이 활발하게 진행되어 지고 있다. MRI System을 이용한 관상동맥(Coronary Artery) Image는 여러 가지 움직임 때문에 사용할 수 있는 영상기법에 제한을 받게 된다 가장 큰 제약은 심장의 움직임에 관한 것인데 이러한 움직임은 ECG Gating을 사용하여 극복할 수 있다. 본 논문에서는 관상 동맥을 촬영하는 영상기법의 개발과 촬영된 영상을 재처리하는 기법을 소개 하고자 한다 ECG Gating을 이용한 영상 기법 및 얻어진 영상을 Morphology, MIP를 이용한 Image processing을 하여 얻어진 영상을 enhance시켜 보았다.

• Journal of the KSME
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• v.50 no.8
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• pp.36-40
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• 2010

심장 내의 와동은 심장 내에서 일어나는 모든 혈류의 흐름에 중요한 역할을 하며, 조영심초음파를 이용하여 이를 정량적으로 측정할 수 있는 방법이 최근에 개발 되었다. 심혈관 질환에 있어서 와동의 측정 및 분석은 기존의 영상 기법으로 설명하기 힘든 환자의 증상이나 혈류역학적 상태를 잘 설명해 줄 수 있을 것으로 기대되고, 심장 질환의 조기 진단 및 치료에 큰 도움을 줄 것으로 생각된다. 심장 내 와동 혈류 측정은 새로운 심혈관계 영상기법으로, 조기에 심기능을 평가할 수 있는 도구로서 매우 유용할 것으로 기대하며 기술적인 문제 등이 보완된다면 임상적인 적용이 점차 확대 될 수 있을 것이라 생각된다.

• Proceedings of the KIEE Conference
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• 2011.07a
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• pp.2039-2040
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• 2011

자기공명영상에서 심장의 기능을 진단에 필요한 심장 영상을 얻기 위해서는 심장의 움직임을 모니터 할 수 있는 ECG나 pulse oximeter 등의 장비로 동기를 맞추어 주기위한 트리거 신호가 필요하다. 본 논문은 심장의 움직임을 다른 장비의 도움 없이 동기화하여 자기공명 심장 영상을 재구성하는 새로운 방법을 나선주사영상기법에 적용하여 제안하였다.

• Journal of KIISE:Software and Applications
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• v.33 no.4
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• pp.418-426
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• 2006

This paper proposes a robust and efficient segmentation method for a cardiac ultrasound image taken from a probe inserted into the heart in surgery. The method consists of three steps: initial boundary extraction, whole boundary modification using confidence competition, and local boundary modification using the rolling spoke method. Firstly, the initial boundary is extracted with threshold regions along the global spokes emitted from the center of an ultrasound probe. Secondly, high confidence boundary edges are detected along the global spokes by competing among initial boundary candidate and new candidates achieved by edge and appearance information. finally, the boundary is modified by rolling local spokes along concave regions that are difficult to extract using the global spokes. The proposed method produces promising segmentation results for the ultrasound cardiac images acquired during surgery.

• Investigative Magnetic Resonance Imaging
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• v.11 no.1
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• pp.1-9
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• 2007

The obstacles for cardiac imaging are motion artifacts due to cardiac motion, respiration, and blood flow, and low signal due to small tissue volume of heart. To overcome these obstacles, fast imaging technique with ECG gating is utilized. Cardiac exam using MRI comprises of morphology, ventricular function, myocardial perfusion, metabolism, and coronary artery morphology. During cardiac morphology evaluation, double and triple inversion recovery techniques are used to depict myocardial fluidity and soft tissue structure such as fat tissue, respectively. By checking the first-pass enhancement of myocardium using contrast-enhanced fast gradient echo technique, myocardial blood flow can be evaluated. In addition, delayed imaging in 10 - 15 minutes can inform myocardial destruction such as chronic myocardial infarction. Ventricular function including regional and global wall motion can be checked by fast gradient echo cine imaging in quantitative way. MRI is acknowledged to be practical for integrated cardiac evaluation technique except coronary angiography. Especially delay imaging is the greatest merit of MRI in myocardial viability evaluation.

• Journal of the Korean Society of Radiology
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• v.81 no.2
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• pp.302-309
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• 2020

Fabry disease is a rare X-linked metabolic disorder that is characterized by the accumulation of glycosphingolipids in various organs, resulting from the deficiency of alpha-galactosidase A. Cardiac involvement is relatively common; myocardial inflammation, left ventricular hypertrophy, and myocardial fibrosis secondary to abnormal lipid deposition in myocytes are often observed. Hence, the diagnosis of cardiac involvement is crucial for evaluating patient prognosis. Cardiac MRI is the standard technique for measuring the function, volume, and mass of the ventricles. It is also useful for myocardial tissue characterizations. The evaluation of native myocardial T1 values can facilitate early diagnosis of cardiac involvement, while measurements of left ventricular myocardial mass can be used to monitor treatment outcomes, in patients with Fabry disease. Consequently, cardiac MRI can provide useful information for diagnosing, monitoring, and treating patients with Fabry disease.

• Investigative Magnetic Resonance Imaging
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• v.3 no.1
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• pp.6-12
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• 1999

Echo Planar Imaging (EPI) Spiral Scan 영상을 초고속 자기공명영상 기법으로서 전체 k-space의 데이터를 한번 scan에 다 받을 수 있기 때문에 데이터 측정시간을 100ms 이내로 단축시킬 수 있다. 이러한 초고속 영상 기법은 최근 활발히 연구되고 있는 뇌기능 영상과 관련하여 중요도가 더욱 커지고 있다. EPI는 직각좌표계에서 데이터를 받기 때문에 재구성은 비교적 쉬우나 eddy current를 많이 야기시키는 단점을 가지고 있다. 반면에 Spiral Scan 영상은 먼저 데이터를 원 또는 직각좌표계로 interpolation을 한 후 재구성하여야 하는 단점이 있으나, 상대적으로 eddy current가 작고, 방향과 무관하게 균일한 point spread function을 가지며, 혈류와 관련한 위상이 스스로 rephasing 되어 심장 영상 등에 유리한 장점이 있다.

• Progress in Medical Physics
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• v.24 no.4
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• pp.278-283
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• 2013

Breast cancer is the leading cause of cancer death in women worldwide and the number of women breast cancer patient was increased continuously. Most of breast cancer patient has suffered from unnecessary radiation exposure to heart, lung. Low radiation dose to the heart could lead to the worsening of preexisting cardiovascular lesions caused by radiation induced pneumonitis. Also, several statistical reports demonstrated that left-sided breast cancer patient showed higher mortality than right-sided breast cancer patient because of heart disease. In radiation therapy, Deep Inspiration Breath Hold (DIBH) technique which the patient takes a deep inspiration and holds during treatment and could move the heart away from the chest wall and lung, has showed to lead to reduction in cardiac volume and to minimize the unnecessary radiation exposure to heart during treatment. In this study, we investigated the displacement of heart using DIBH CT data compared to free-breathing (FB) CT data and radiation exposure to heart. Treatment planning was performed on the computed tomography (CT) datasets of 10 patients who had received lumpectomy treatments. Heart, lung and both breasts were outlined. The prescribed dose was 50 Gy divided into 28 fractions. The dose distributions in all the plans were required to fulfill the International Commission on Radiation Units and Measurement specifications that include 100% coverage of the CTV with ${\geq}95%$ of the prescribed dose and that the volume inside the CTV receiving >107% of the prescribed dose should be minimized. Scar boost irradiation was not performed in this study. Displacement of heart was measured by calculating the distance between center of heart and left breast. For the evaluation of radiation dose to heart, minimum, maximum and mean dose to heart were calculated. The present study demonstrates that cardiac dose during left-sided breast radiotherapy can be reduced by applying DIBH breathing control technique.

• Journal of the Korean Society of Radiology
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• v.82 no.2
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• pp.429-434
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• 2021

Amyloidosis is a multisystemic disease characterized by the accumulation of abnormal proteins in extracellular spaces in various organs, with frequent involvement of the myocardium. We report a case of a patient who had cardiac amyloidosis with a trend of reduction in native T1 and T2 values and extracellular volume fraction on serial cardiac magnetic resonance imaging after chemotherapy and stem cell transplantation. The native T1 value and the extracellular volume fraction are closely associated with tissue amyloid burden in amyloidosis patients. This case demonstrated that cardiac magnetic resonance imaging may be used as a non-invasive and quantitative biomarker in the treatment monitoring of amyloidosis.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.2
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• pp.132-139
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• 1989

We have designed a real-time Cardiac digital substraction angiography system (C-DSA) and tested the system for the diagnosis of Cardiac patients. The system was developed by interfacing a radiographic angiography system to a computerized motional image analysis system. This new cardiac DSA can perform the real time processing of averaging and subtraction of the 32 image frames to measure the volume changes of the left ventricle after elimination of motional artrifacts, caused by the heart contraction of beats per minute in average. Each frame has a resolution of 512 x 512 pixels and 256 gray levels. Two image data with maximal and minimal volume were moved to the interfaced IBM PC computer system by high speed computer link line for computation of the heart's contraction parameters. First, the boundary of the left ventricule was detected using a dynamic programming of the gray levels, and its volume was computered to determine the parameters, such as the maximal volume of end-diastolic volume (EDV), the minimal volume of end systolic volume (ESV), and ejection fraction (EF).