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Comparison between adverse effects of low and usual doses of intravenous aminophylline (정주 아미노필린의 투여 농도에 따른 부작용에 관한 연구)

  • Kim, Bok Ki;Lim, Dae Hyun;Ahn, So Hyun;Kwak, Jong Hoon;Kim, Jeong Hee;Son, Byong Kwan
    • Clinical and Experimental Pediatrics
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    • v.52 no.4
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    • pp.441-445
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    • 2009
  • Purpose : Some patients develop side effects from theophylline even at low serum concentrations. We designed a prospective study to evaluate the side effects of theophylline. Methods : A Prospective, controlled trial study was conducted. The low-dose group received an intravenous continuous aminophylline dose of 5 mg/kg/day on the first day and subsequently 10 mg/kg/day on the following two days. The usual-dose group received 10 mg/kg/day for three days and the control group received normal saline for three days. Heart rate, respiratory rate, serum concentration of theophylline, and four adverse events (irritability, sleep disturbance, jitter, and vomiting) were checked at the time of admission and at 2, 12, 24, 48, and 72 h after the start of aminophylline infusions. Results : Nine patients out of 37 in the low-dose group and six of 21 in the usual-dose group dropped out because of uncontrolled irritability. The serum concentrations of theophylline in dropouts ($3.68{\pm}1.93$ ig/mL) and participants ($4.47{\pm}2.45$ ig/mL) were not significantly different. Irritability was a more frequent side effect in the usual-dose group at 12 h, but there was no difference between the low-dose and usual-dose groups in terms of vomiting, sleep disturbance, and jitter. Most of the severe adverse effects were observed in children below two years of age. Conclusion : Some patients dropped out regardless of the initiating aminophylline dose, especially patients under the age of two years.

Neutrophil-Lymphocyte Ratio as a Prognostic Factor in Terminally Ill Cancer Patients (말기 암 환자에서 호중구-림프구 비가 예후인자로서 생존기간에 미치는 영향)

  • Cho, Wan-Je;Hwang, Hee-Jin;Lee, Yong-Jae;Son, Ga-Hyun;Oh, Seung-Min;Lee, Hye-Ree;Shim, Jae-Yong
    • Journal of Hospice and Palliative Care
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    • v.11 no.4
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    • pp.181-187
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    • 2008
  • Purpose: In order to establish efficient palliative treatment plans. It is important to estimate the survival time of a terminally ill cancer patient as accurate as possible. Proper estimation of life expectancy aids not only in improving the quality of life of the patient, it also promotes productive communication between the medical staff and the patient. The aim of this study is to determine the efficacy of neutrophil-lymphocyte ratio as a predictor of survival time in terminally ill cancer patients. Methods: Between January 2004 and June 2007, 67 terminally ill cancer patients who were admitted or transferred for palliative care, were included. Patients were categorized into three groups by Neutrophil-Lymphocyte Ratio. Demographic characteristics, clinical characteristics and blood samples were analyzed. Results: In univariate analysis, survival time of the highest Neutrophil-Lymphocyte Ratio group (${\geq}12.5$) was significantly shorter than that of the others (hazard ratio (HR)=3.270, P=0.001). After adjustment for low performance status (ECOG score 4) and dyspnea, high Neutrophil-Lymphocyte Ratio (${\geq}12.5$) was significantly and independently associated with short survival time (HR=2.907, P=0.007). Neutrophil-Lymphocyte Ratio was also significantly increased before death (P=0.001). Conclusion: Neutrophil-Lymphocyte Ratio can be useful in predicting life expectancy in terminally ill cancer patients.

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Migrant Multi-Cultural Family Women's Life Quality Related to Oral Health: Survey in Dae-Gu (다문화가족 이주여성의 구강건강관련 삶의 질: 대구지역 조사)

  • Jeon, Eun-Suk;An, Seo-Young;Choi, Yeon-Hee
    • Journal of dental hygiene science
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    • v.11 no.3
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    • pp.181-187
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    • 2011
  • This study conducted oral examinations and individual interviews on migrant multi-cultural family women in Daegu and measured their socio-demographic characters, oral health conditions and OHIP-14 in an aim to investigate the relevance between the oral health of migrant multi-cultural family women living in some big cities and their quality of life. Based on data finally collected from 189 women, the t-test, ANOVA and binary logistic regression analysis were conducted and the conclusions are as follows: The average number of decayed teeth was 2.23, loss teeth was 1.48, and treated teeth was 5.58. Women from the Philippines had more number of loss teeth than those from other countries, and women from China relatively had a small number of filled permanent teeth. The quality of life related to oral health was found to be poor in proportion to the number of loss teeth. A comparison of life quality related to oral health depending on loss teeth showed that life quality related to oral health was lowest in the areas of mental discomfort, physical ability decrease, mental ability decrease, social ability decrease and social disadvantage. Life quality related to oral health was found to be low in proportion to the number of permanent teeth with decay experience and poor monthly household income, which shows that the number of permanent teeth with decay experience and monthly income are mostly related to life quality related to oral health. As migrant multi-cultural family women's life quality related to oral health is low in proportion to the number of loss teeth and decayed teeth, it needs to develop a program to improve their oral healthrelated life quality and conduct follow-up research to verify its effect.

Association between Oral Health Related Quality of Life(OHQoL) and Oral Health Outcome in Adults over 50 Years Old (50대 이상 장노년층의 구강건강 관련 삶의 질과 구강 건강 결과의 관련성)

  • Cho, Young-Sik;Lim, Soon-Ryun;Hwang, Hye-Rim
    • Journal of dental hygiene science
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    • v.11 no.4
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    • pp.305-310
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    • 2011
  • The purpose of this study was to investigate association between oral health related quality of life(OHRQoL) and health outcome, such as evaluated oral health state, perceived health state and perceived oral health state. 148 of individuals over 50 years old completed a self-reported questionnaire on Oral Health Impact Profile(OHIP-14) and oral examination was perfomed. 9.5% of respondents reported no problems or discomfort using OHIP-14. The most frequently reported problems were physical pain(69.8%) and psychological discomfort(63.5%). 43.9% of the individuals rated their health and oral health as poor and 54.7% were dissatisfied with their oral health. The study showed association between number of DMFT, missing teeth, perceived health state, perceived oral health state, oral health satisfaction and oral health related quality of life. Perceived heath sate was correlated with oral health related quality of life. But the study showed no association between DMFT, number of missing teeth and oral health related quality of life.

The Comparison of Recognizing Personal Health Record Between Healthcare Students and Medical Students (보건대학생과 의과대학생 간의 개인건강기록(PHR) 인식 비교)

  • Baek, Eun-Hae;Lim, Sung-Won;Kim, Han-Kyoul;Rhee, Hyun-Sill
    • Journal of Digital Convergence
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    • v.10 no.10
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    • pp.373-382
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    • 2012
  • With the paradigm shifts towards consumer-centered health service, it is expected that more health care consumers will keep their health information and manage their own health in the future. Thus, this study was conducted to compare "Understanding", "Utilization" and "Management" of Personal Health Record(PHR) between medical users(healthcare students) and health care providers(medical students). We collected data from 208 health and medical students via using self-reported questionnaires form April to June, 2011. The collected data were analyzed using frequency, t-test, Chi-square on SPSS 19.0 version. There was no significant difference in "Understanding" of PHR between two groups. Looking at the order of the importance of PHR contents, two groups equally emphasized medical records, surgical history, and test results. There was significant difference in both time and effectiveness of PHR(p=0.02). Intergrated type of PHR was preferred by both groups. Recently, PHR reflects needs and demands of users more than ever. However there are many limitations to promote the utilization. In the future, it is necessary to implement targeted strategies for the elderly groups and specific types of disease.

Effects of After-school Forest Healing Program Activities on Infant's Pro-social Behavior and Self-efficacy (방과후 산림치유프로그램 활동이 유아의 친사회적 행동과 자아효능감 향상에 미치는 영향)

  • Jang, Cheoul-Soon;Koo, Chang-Duck
    • Korean Journal of Environment and Ecology
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    • v.31 no.6
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    • pp.595-605
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    • 2017
  • This study was intended to investigate the effects of after-school forest healing programs on the pro-social behavior and self-efficacy of young children using the attributes of forest and the forest healing factors. The children attending a kindergarten located in ${\bigcirc}{\bigcirc}$ - dong, Cheongju city were divided into a test group which participated in the forest healing program activities and a control group which participated in the regular programs of the kindergarten but not in the forest healing program. Each group consisted of 20 boys and girls aged 3 to 5 years. The forest healing program was conducted once a week from 10 April to 10 July in 2017 for a total of 12 sessions, and each session lasted one hour (60 minutes). The pro-sociality behavior and self-efficacy test of the children was conducted before and after the forest healing program, and the data were analyzed using SPSS 18.0 program. The result showed that the pro-social behaviors that indicated the ability to execute the positive action and the self-efficacy that indicated the self-confidence were statistically significant (p<0.05). The young children who participated in the forest healing program improved their self-esteem through positive thoughts from being with their peer in nature. Moreover, they increased not only ecological knowledge but also consideration for others and cooperative spirit. They also greatly improved the ability to control personal emotion and the ability to form the personal relationship which are the sub-factors of pro-sociality, the ability to adapt to the early childhood education institution, and the physical efficacy which is the sub-factor of self-efficacy. It was concluded that the after-school forest healing program had a positive impact on pro-social behavior and self-efficacy.

A Study on the Effect of the Forest Healing Programs on Teachers' Stress and PANAS (산림치유프로그램이 교사의 스트레스와 긍정·부정감정에 미치는 효과)

  • Park, Suk-Hee;Yeon, Poung-Sik;Hong, Chang-Won;Yeo, Eun-Hee;Han, Sang-Mi;Lee, Hye-Young;Lee, Hyo-Jung;Kang, Jae-Woo;Cho, Hyun-Sol;Kim, Youn-Hee
    • Korean Journal of Environment and Ecology
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    • v.31 no.6
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    • pp.606-614
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    • 2017
  • This study analyzed the effect of forest therapy program on reduction of stress of teachers and their positive and negative emotions based on the survey of 221 teachers who participated in the overnight Happiness School Edu-healing Camp held for teachers by the National Center for Forest Healing. For data analysis, a paired sample t-test was conducted using the SPSS 24.0 program to examine the difference in the stress reaction index of teachers and their positive and negative emotions before and after their participation in the forest therapy program. The results indicated that teachers who participated in the program showed a significant decrease in the stress response index and the values of sub-domain such as physical symptoms, depression symptoms, and anger symptoms. Moreover, all teachers exhibited a significant decrease in stress. This result verifies that the forest therapy program is effective in reducing the stress of teachers and their negative emotions. These results are expected to be used to promote more active forest therapy programs for teachers exposed to a high level of stress.

Berg Balance Scale Score Classification Study Using Inertial Sensor (관성센서를 이용한 버그균형검사 점수 분류 연구)

  • Hong, Sangpyo;Kim, Yeon-wook;Cho, WooHyeong;Joa, Kyung-Lim;Jung, Han-Young;Kim, K.S.;Lee, S.M.
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.11 no.1
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    • pp.53-62
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    • 2017
  • In this paper, we present the score classification accuracy of BBS(Berg Balance Scale) which is the most commonly used balance evaluation tool using machine learning. Data acquisition was performed using the Noraxon system and an inertial sensor of Noraxon system was attached to the body in 8 locations (left and right ankle, left and right upper buttocks, left and right wrists, back, forehead). Based on the 3-axis accelerometer of the inertial sensor, the feature vector STFT(Short Time Fourier Transform) and SAM(Signal Area Magnitude) were extracted. Then, the items of the BBS were divided into static movement and dynamic movement depending on the operation characteristics, and the feature vectors were selected according to the sensor attachment positions which affect the score for each item of the BBS. Feature vectors selected for each item of BBS were classified using GMM(Gaussian Mixture Model). As a result of the accuracy calculation for 40 subjects, 55.5%, 72.2%, 87.5%, 50%, 35.1%, 62.5%, 43.3%, 58.6%, 60.7%, 33.3%, 44.8%, 89.2%, 51.8%, 85.1%, respectively.

The effect of group sociality play in sociality of autistic adolescent (집단사회성놀이가 자폐청소년의 사회성에 미치는 효과)

  • Woo, Hee-Soon;Won, Sung-Yoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.6
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    • pp.98-105
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    • 2016
  • Group play for sociality is a therapeutic method involving a mixture of various factors, such as targeted activities, perceptions, and physical mobility required in daily life, through group activities to encourage self-expression for the purpose of facilitating sociality. This study was conducted in order to verify its effects by applying it to autistic adolescents who lack communicative ability with others and ultimately to improve their interpersonal relationships and sociality. This study applied a single pre- and post-test experiment design to 8 autistic adolescents with lack of sociality who use a daycare center in Daejeon. The group play for sociality program consisted of two sessions a week for 7 weeks from October to December 2013 for a total of 14 sessions. The sociality of the adolescents before and after the intervention was analyzed by the Wilcoxon signed-rank test. As a result of the study, the total grades of the E-CLAC and social maturity test showed significant changes from $39.88{\pm}6.78$ to $47.00{\pm}4.28$ and $49.96{\pm}28.00$ to $61.36{\pm}21.75$, respectively. In detail, there were significant changes in the sub-items, such as adjustment in group, following guidance, and increasing behavioral frequency. In conclusion, it was shown that the combined effect of the group activities, including group play for sociality and play activities taking into consideration the developmental stage of the participants, led to a significant improvement in the sociality of the autistic adolescents.

A Study of Disease Prevalence According to Green Tea Consumption (녹차 섭취기간에 따른 질병 발현 연구)

  • 백송남;진현화;이현정;김양하;양정례
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.31 no.5
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    • pp.856-861
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    • 2002
  • It has been reported in animal and human studies that green tea shows a health protective characteristics. In the present study, we investigated the disease prevalence according to chronic green tea consumption in 92 subjects (mean age: 59.548.9, men: 41, women: 51) living in green tea cultivation village. The consumption of green tea and other life-style characteristics were ascertained by a questionnaire. The subjects were divided into three groups according to the period of green tea consumption (0, < 10 year, and $\geq$ 10 year). For green tea consumption groups, most of the subjects have been drinking green tea in order to protect disease and recognized the effects of green tea as detoxification of alcohol and smoking, protection of cold or release from fatigue. There were no significant differences in drinking and smoking, physical activity, and a cold prevalence among the groups. Green tea consumption was associated with lower levels of prevalence of tooth decay as well as the osteoporosis. The score of dietary habits was higher by increasing green tea consumption period (p<0.05). Consequently, chronic green tea consumption can be considerably effective in health promotion.