• The Journal of the Petrological Society of Korea
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• v.9 no.4
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• pp.254-270
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• 2000

To clarify the geological structure of North Sobaegsan Massif in the Sangunmyeon area, Bonghwagun, Korea, where the Yecheon Shear Zone passes and the NE-SW and E-W trending structural lineaments are developed, the rock-structures of its main constituent rocks(Precambrian Won-nam Formation and Mesozoic Hornblende Granite) were examined. In this area, the geological structure was formed at least by four phases of deformation after the formation of gneissosity or schistosity of the Wonnam Formation: one deformation before D2 ductile shearing related to the for-mation of the Yecheon Shear Zone and two deformations after that. The NE-SW and E-W trending structural lineaments were formed by a giant open or gentle type of F4 fold, and their trends before D4 deformation are interpreted to be parallel to the orientation(ENE-WSW trend) of folded surface in the F4 hinge zone. The structural features of Dl-D3 deformations and their relative occurrence times are as follows. Dl deformation is formative period of the boudin structures and ENE-WSW trending isoclinal folds with sub-horizontal hinge lines and steeply inclined axial surfaces. D2 deformation is that of the mylonite foliation, stretching lineation and Z-shaped asymmetric folds related to top-to-the ENE dextral strike-slip shearing on the distinct foliations of Wonnam Formation(after intrusion of Mesozoic Hornblende Granite). D3 deformation is that of the ENE trending S-shaped asymmetric folds with sub-horizontal hinge lines and axial surfaces related to normal-slip shearing on the distinct foliations. It is expected that the result will be contributed to as valuable data for interpreting the tectonic evolution of the North Sobaegsan Massif and the Northeast Ogcheon Belt whose tectonic lineaments are changed from NE-SW to E-W trends at the Sindong-Bonghwa line.

• Proceedings of the Korean Society of Developmental Biology Conference
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• 2003.10a
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• pp.62-62
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• 2003

Aquaporin (AQP) family protein은 일종의 수분 전달 통로 역할을 하는 단백질로 AQP를 통한 수분의 조절은 삼투압을 통한 물의 이동과 함께 조직내 정상적인 수분의 상성 유지에 필수적이다. 현재까지 11종의 AQP이 신장·뇌·정소·안구 등에서 발현이 확인되었다. AQP9은 물 뿐 아니라 carbamide, polyol, purine, pyrimidine, urea, glycerol 등의 이동에 관여한다. 본 연구에서는 생쥐에서 출생 후 성체에 이르는 동안 정소 내 AQP9의 발현, Leydig cell의 분화에 따른 AQP9의 발현을 조사하였다. 1, 2, 4, 8주령의 정소로부터 semiquantitative RT-PCR 및 real time PCR 법으로 AQP9의 발현을 분석한 결과 1주령에서는 발현되지 않았고 2주령에서는 미량이 발현되기 시작하였고, 4주령에서는 성체의 1/2수준으로 발현량이 급격히 증가하였고 성체에서는 다량으로 발현됨이 확인되었다. Semiquantitative RT-PCR 법과 real time PCR법을 비교할 때 주령별 발현 양상은 유사하였으나 4주령과 성체에서는 두 시험법 사이에 양적인 차이가 있었다. 면역조직화학염색 결과 주로 Leydig cell에서 AQP9의 발현이 확인되었다. 성체의 정소 균질액의 Western blot 상에서 분자량 80, 55, 35 및 23 kDa의 항원이 검출되어 dimer, trimer 형태로 존재할 가능성과 당쇄 결합에 의한 단백질의 변형이 있는 것으로 추정된다. 미성숙 개체의 정소에서는 23 form이 확인되는 반면 성체에서는 35 kDa form이 주로 발현되므로 정소에서 발현되는 AQP9의 경우 Post-translation 수준에서 AQP9의 변형이 수반되는 것으로 사료되며 AQP9의 기능과의 연관성은 추후 연구되어야 할 것이다. Leydig cell은 fetal 및 adult type 2종의 세포가 정소발달 과정에 출현, 사멸, 분화하며 이들은 각기 정소발달, 성숙과 정자형성에 필요한 steroidogenesis에 관여한다. 정소 내 AQP9의 발현은 17beta HSD의 발현 양상과 같게 나타나므로 성적 성숙에 따른 정소 내 AQP9의 발현의 증가는 adult type Leydig cell의 분화와 관련된 것으로 추측된다. 성체의 정소로부터 분리한 Leydig cell-enriched culture에 hCG를 처리한 결과 배양체의 AQP9의 발현이 증가하므로 AQP9은 LH 수용체 하위 신호전달과정을 통해 Leydig cell의 steroidogenesis 또는 생성된 steroids의 분비에 요구되는 수분 및 중성용질의 이동에 관여하는 것으로 사료된다.

• Journal of the Korean Geotechnical Society
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• v.17 no.6
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• pp.135-148
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• 2001

In this study, an assessment method was proposed to evaluate the pullout resistance between geosynthetic and backill soil by using a stress-strain relationship of the orthotropic composite material subjected to both longitudinal and vertical loadings. For this analysis friction characteristics of geosynthetic-soil and stress-strain relationships subjected to soil confined pressure were investigated by performing the laboratory pullout tests for three types of geosynthetics and performing the confined extension tests far seven types of geosynthetics having geotextiles, composite geosynthetics and geogrids. A comparison was made between unconfined an confined moduli far each geosynthetic material to quantify the soil confinement effect on stress-strain properties. A comparison was also made between the relative increase of moduli at the same strain level among the seven geosynthetic materials to demonstrate the different responses of these geosynthetic materials under soil confinement. Based on the proposed procedure, it was shown that values of the increased tensile force are applicable fur the evaluation of friction strengths between five types of geosynthetics and sands in light of the soil confinement effect.

• Journal of Korean Society of Steel Construction
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• v.9 no.2 s.31
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• pp.193-204
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• 1997

In order to quantify the relationships of the important physical factors relating failure to strong earthquake loading, the plastic fatigue problems for structural components under repeated loading were reviewed first. A new concept of very low cycle fatigue failure for structural components under severe cyclic excitations as in strong earthquakes was represented. Also, an experimental study was made of the very low cycle fatigue failure of structural steel elements. It was attempted to realize the ultimate failure in the course of loading repetitions of the order of several to twenty. The test specimen had a form of rectangular plate, representing a thin-plated element in a steel member as wide-flange cross section. It was subjected to uniaxial loading repeatedly, until complete failure takes place after undergoing inelastic buckling, plastic elongation and/or their combination. It was seen as a result that the state of the ultimate failure is closely related to the maximum strain at the extreme fiber in the cross section.

• Journal of Elementary Mathematics Education in Korea
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• v.9 no.1
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• pp.39-64
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• 2005

The purpose of this study is to transform questions in the 7th curriculum to open-ended problems and exam students' attitude towards open-ended problems. Research questions in this thesis are as follows: First, to transform questions in the 7th curriculum to open-ended problems and apply to a class in the fourth grade D elementary school. Second, to find how students respond to learning mathematics with open-ended problems. As a result of this study, the following are identified. First, the students showed positive reactions towards learning mathematics with open-ended problems. Those experience with open-ended problems make student solve mathematics problems with interest and confidence. Second, both good and bad students in the math class show interest and concentration toward open-ended problem. But a few students show less interest towards those problems. Third, through discussion about problem-solving with open-ended problems, students take part in math class actively and show respect one another. Fourth, especially students show more interest and confidence towards the open-ended problems transformed from mathematics textbook and like the constructive open-ended problems.

• Physical Therapy Korea
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• v.10 no.4
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• pp.85-94
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• 2003

본 연구에서는 근골격계 통증이 자세유지와 균형능력에 핵심이 되는 중력중심 이동에 미치는 영향에 대해 알아봄으로서, 균형과 자세에 영향을 주는 다양한 요소들에 대한 새로운 접근을 시도해 보고자 한다. I-병원의 입원 및 외래 환자 중 신경계 손상이 없고 중력중심 이동에 직접적인 영향을 줄 수 있는 하지에 정형외과적 장애가 없으며, 전정계 손상이나 시력장애로 인한 균형에 문제가 없이 근골격계 질환으로 요통과 견통을 주소로 하는 71명의 환자(남자 38, 여자 33; 평균연령=44, 표준편차=13.8, 범위=19~79)와 신경계, 근골격계 및 평형감각에 문제가 없는 정상인 30명의 대조군(남자 16, 여자 14; 평균연령=39.2, 표준편차=13.7, 범위=21~72)을 대상으로 전산화된 힘판을 이용하여 중력중심 이동의 궤적을 표준편차값으로 측정하였다. 측정된 중력중심 이동값은 두 군간에 상이한 차이를 보이고 있음이 검증되었다(p<.01). 또 측정된 여러 변수들의 중력중심 이동에 대한 영향력을 알아보기 위해 나이, 체중 및 신장과 중력중심 이동과의 상관분석 결과 중력중심 이동의 15.8%를 체중의 변화에 의한 것으로 설명할 수 있다는 결과를 얻었으며, 그 외의 변수들과의 연관성에 대해선 유의미한 차이가 없었다(p<.01). 결과적으로 근골격계 통증은 올바른 자세유지와 균형유지를 위한 감각통합과 반응과정에 직접, 간접적으로 영향을 미치고 있다. 따라서 중력 중심 이동이 크면 클수록 중심을 잡기 위한 근육활동으로 추가적인 에너지가 사용되고, 편중된 중력중심 이동은 근골격계에 무리한 부담을 주어 통증을 증가시킬 수 있을 것이다. 또 통증으로 인한 중력중심 이동은 이를 보상하기 위해 신체 먼 곳에서의 이차적인 변형을 초래하여 각종 근골격계 증상의 원인이 될 수 있으므로 근골격계에 대한 적절한 치료는 통증을 감소시켜 자세의 이차적인 변형을 막고 자세유지 시 작용하는 근육의 에너지 효율을 높일 수 있을 것으로 사료된다.

• The Mathematical Education
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• v.58 no.4
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• pp.545-566
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• 2019

The purpose of this study is to show that research community activities can contribute to the professional development in respect of average concepts and mathematical creativity. In the community, activities were undertaken to transform the existing task into the task that contributes to the manifestation of creativity. In this process, researchers tried to connect the theory with the practice of the class, and the teacher acted as an active learner. The findings show that the teacher who had difficulty in teaching average could overcome difficulties, and also derived the way of task modification and strategies necessary for teaching average. The modified task induced improvements in students' achievement levels, which led to change in teachers' perspective on the relationship between mathematical creativity and learning. Research community activities have been shown to have contributed to improvements with regard to both teaching the average and promoting mathematical creativity.

• Journal of Genetic Medicine
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• v.8 no.1
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• pp.67-70
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• 2011

Constitutional trisomy 8 mosaicism (CT8M) is a relatively rare aneuploidy in humans with characteristic phenotypes including typical craniofacial feature (such as deformed skull, prominent forehead, low-set and/or dysplastic ears), skeletal malformation, cardiac anomaly, renal malformation, cryptochidism, varying degree of developemental delay. Due to the extremely variable phenotypic and cytogenetic expression, CT8M has gone undiagnosed in certain patients. We report a 28-year-old women with secondary amenorreha without characteristic CT8M phenotype. Chromosomal analysis showed a CT8M (47,XX,+8[9]/46,XX[41]).

• Neonatal Medicine
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• v.15 no.1
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• pp.89-93
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• 2008

Duplication of chromosome 12p has been rarely reported and are thought to be associated with congenital malformations and impaired development. We report a baby boy born with multiple dysmorphic features and congenital malformations. His karyotype was 46,XY, add(12)(p13.3). He has suffered from intrauterine growth restriction at birth. He showed abnormal cranio-facial findings such as microcephaly, hypognathia, clepft palate and low set ear. He presented with absence of uvula, micropenis and rocker bottom features of both feet, congenital heart disease, poor corticomedullary differentiation of kidney, and sensorineuronal hearing loss. We have been follow up him for seizure disorder and delayed development at out patient department.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.12 no.3
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• pp.51-61
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• 2012

This paper suggests an algorithm that obtains Directed Graph Minimum Spanning Tree (DMST), using Prim MST algorithm which is Minimum Spanning Tree (MST) of undirected graph. At first, I suggested the Prim DMST algorithm that chooses Minimum Weight Arc(MWA) from out-going nodes from each node, considering differences between undirected graph and directed graph. Next, I proved a disadvantage of Prim DMST algorithm and Chu-Liu/Edmonds DMST (typical representative DMST) of not being able to find DMST, applying them to 3 real graphs. Last, as an algorithm that can always find DMST, an advanced Prim DMST is suggested. The Prim DMST algorithm uses a method of choosing MWA among out-going arcs of each node. On the other hand, the advanced Prim DMST algorithm uses a method of choosing a coinciding arc from the out-going and in-going arcs of each node. And if there is no coinciding arc, it chooses MWA from the out-going arcs from each node. Applying the suggested algorithm to 17 different graphs, it succeeded in finding the same DMST as that found by Chu-Liu/Edmonds DMST algorithm. Also, it does not require such a complicated calculation as that of Chu-Liu/Edmonds DMST algorithm to delete the cycle, and it takes less time for process than Prim DMST algorithm.