• 대한의용생체공학회:의공학회지
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• 제28권2호
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• pp.212-217
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• 2007

As a preliminary study for the development of electrical stimulation strategy of artificial retina, we set up a method fur the reconstruction of input intensity variation from retinal ganglion cell(RGC) responses. In order to estimate light intensity variation, we used an optimal linear filter trained from given stimulus intensity variation and multiple single unit spike trains from RGCs. By applying ON/OFF stimulation(ON duration: 2 sec, OFF duration: 5 sec) repetitively, we identified three functional types of ganglion cells according to when they respond to the ON/OFF stimulus actively: ON cell, OFF cell, and ON-OFF cell. Experiments were also performed using a Gaussian random stimulus and a binary random stimulus. The input intensity was updated once every 90 msec(i. e. 11 Hz) to present the stimulus. The result of reconstructing 11 Hz Gaussian and binary random stimulus was not satisfactory and showed low correlation between the original and reconstructed stimulus. In the case of ON/OFF stimulus in which temporal variation is slow, successful reconstruction was achieved and the correlation coefficient was as high as 0.8.

• 한국HCI학회:학술대회논문집
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• 한국HCI학회 2008년도 학술대회 1부
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• pp.697-702
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• 2008

2007년 현재 전 세계적으로 모바일 기기 사용 인구수는 약 30억 명으로 전 세계 PC사용자 수의 두 배에 달한다. 모바일 디스플레이는 작은 크기로 인해 휴대성이 높은 등 많은 장점을 갖고 있지만, 소형화와 전력 절감을 위해 얇은 디스플레이 패널과 저성능 이미지 센서를 채택하는 등 대형 디스플레이에 비해 색상표현력이 떨어질 수 밖에 없다. 따라서 본 연구에서는 모바일 디스플레이 자체의 성능이 떨어지더라도 사람의 눈에 인식되기 용이하게 색채이론에 입각해 이미지 환경을 변경하는 방법을 제안한다. 사람의 눈은 망막상의 색신경이 어떤 색의 자극을 받게 되면 그 색의 보색에 대한 감수성이 높아지고, 명암차이가 분명한 색상들을 나열하면 반대 밝기에 대한 민감도가 높아진다. 사람의 시각신경에서 느끼는 색채에 대한 감성적인 색상처리(RGB의 채도를 증가 시키거나 다이나믹 레인지의 확장과 보색대비의 강조에 따른 변화)를 통하여 얻은 데이터를 비교 분석 한다. 그 결과 적용 전의 이미지보다 적용 후의 이미지의 인식률이 높아지고 화질이 향상됨을 알 수 있다.

• 대한감각통합치료학회지
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• 제2권1호
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• pp.21-32
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• 2004

Objective : Effect of treadmill exercise on hippocampal neural cell proliferation under normal conditions and alcohol intoxication conditions has been recently studied; however, this effect under sensory stimulation application has not clarified yet. In the present study, the effect of compression stimulation application on hippocampal neural cell proliferation in the dentate gyrus in normal and alcohol intoxicated rats was investigated. Methods : Experimental design: comparative investigation on number of 5-Bromo-2'-deoxyuridine(BrdU)B-positive cells in dentate gyrus 5 days after commencement. Setting: animal laboratory. Participants: male Sprague-Dawley rats of 3weeks old in age weighing $80{\pm}10gm$. Intervention: animals were randomly assigned into 4 groups; control-rest group(n=8), control-compression group(n=8), alcohol intoxication-rest group(n=8) and alcohol intoxication-compression group(n=8). Animals of the alcohol intoxicated groups were injected intraperitoneally with alcohol(2g/kg) twice per day for 3 days. All animals were injected BrdU(50mg/kg) intraperitoneally, and rats compression stimulation application groups were compressed using sphygmomanometer cuff times per day, for 5 days following alcohol administration. Measures: mean number of BrdU-positive cells in dentate gyrus was observed via immunohistochemistry. Results : Compression stimulation application significantly increased the number of BrdU-positive cells in the dentate gyrus. Also, treatment with alcohol for 3 days inhibited cell proliferation, and compression stimulation application alleviated alcohol-induced inhibition of new cell formation. Conclusion : These results suggest the possibility that compression stimulation application may help in improvement following alcohol-induced brain damaged.

• 대한감각통합치료학회지
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• 제8권1호
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• pp.73-86
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• 2010

섭식기술의 문제는 성장, 학습, 의사소통, 다른 아동과의 상호작용 등 삶의 모든 면에 영향을 줄 수 있다. 구강섭식은 입을 열고 음식/액체를 입속에 넣고 삼키는 것이다. 본 문헌연구의 목적은 아동의 섭식과 관련된 평가방법과 중재방법에 대해 알아보는 것이다. 섭식은 아동 초기 발달의 중요한 요소이며 일상생활 참여를 촉진한다. 아동이 음식을 먹을 때 받아들이는 방법에 차이가 있다. 그 이유로는 음식으로부터 제공되는 감각자극의 등록과 해석의 과정을 거쳐 섭식행동으로 나타나기 때문이다. 감각처리 문제로 인한 섭식의 문제는 촉각과민성, 구강거부, 촉각과소반응, 구강실 행증으로 분류할 수 있다. 섭식문제의 평가 가운데 감각처리 과정에서 나타날 수 있는 문제들을 확인하고 중재계획을 세우기 위해서는 섭식과 관련된 신경학적 과정을 이해하고 섭식과 관련된 감각처리의 특성을 아는 것이 중요하 다. 또한 감각처리와 관련되어 야기된 섭식문제의 중재방법을 고찰하는 것은 의의가 있으며, 이는 섭식에 관한 효율적인 접근을 통해 아동들에게 보다 나은 삶을 제공할 수 있으리라 기대된다.

• 동의생리병리학회지
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• 제27권3호
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• pp.327-330
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• 2013

The purpose of this study is to report a clinical progress of treatment of sequelae caused by removal of facial schwannoma through Korean medicine. A patient was diagnosed with facial schwannoma by MRI on 4th June 2012 in local university hospital, he had right facial palsy, auditory hypersensitivity, dizziness after removal of facial schwannoma. Between 25th July 2012 and 26th January 2013, he was treated with acupuncture, cupping, electro-acupuncture every week and observed by House-Brackmann facial nerve grading system(H-B scale) and MoReSS every month. He had 29 times treatments. At the first of treatment, his state was Grade IV (H-B scale), 4/8(facial nerve grading), 10 points during action 7 points during rest(MoReSS) and he had severe facial palsy, ill-acrimation, auditory hypersensitivity. At the middle of treatment, October 2012, symptoms improved. State was Grade III (H-B scale), 5/8(facial nerve grading), 7 points during action 3 points during rest(MoReSS). Severe facial palsy improved ; Forehead creasing and union motor function recovered, he was able to close his eyes so ill-acrimation improved. At the end of treatment, January 2012, state was Grade II (H-B scale), 7.5/8(facial nerve grading), 3 points during action 1 point during rest(MoReSS). He had only occasional tinnitus and auditory hypersensitivity. Acupuncture and electro-acupuncture are estimated to be good for facial palsy after removal of facial schwannoma. More cases are required to develop treatment of facial palsy.

• 동의생리병리학회지
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• 제27권5호
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• pp.672-676
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• 2013

The purpose of this study is to report that a patient suffered from Common Peroneal Neuropathy (CPN) caused by ankle sprain was improved by acupuncture plus electro-acupuncture. In this study, the patient was diagnosed with magnetic resonance image(MRI) and electomyography(EMG). We treated at acupoints ST36, ST41, SP9, GB34, GB39 and LR3 by acupuncture plus electro-acupuncture twice a day for 16 days; a total of 30 times. We used evaluation scale including muscle manual testing(MMT) and visual analogue scale (VAS). MMT changed from Grade 0 to Grade 5 and VAS changed from 10 to 2 after treatment for 16days with hospitalization. Though it is a case report, these results suggest that acupuncture and electrical acupuncture might have valid effect on CPN in controlled environment.

• 대한물리의학회지
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• 제9권4호
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• pp.415-424
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• 2014

PURPOSE: This study examined the effect of high-frequency transcutaneous electrical nerve stimulation (TENS) and San-Yin-Jiao (SP6) acupressure on primary dysmenorrhea. Furthermore, the difference in effectiveness between the two methods were compared. METHODS: Twenty-six students participated in this study, and were randomly assigned to a high-frequency TENS group(experimental 1, n=9), a San-Yin-Jiao (SP6) acupressure group(experimental 2, n=9), and no treatment group(control, n=8). They were assessed and treated on the first day of their menstruation. The TENS protocol included applying 20 minutes of stimulation with a frequency of 100Hz, $100{\mu}sec$ pulse width. Four electrodes were placed on the skin 3 cm from midline at T12-L1 and S2-3 paravertebral muscles. San-Yin-Jiao (SP6) acupressure should be applied with the thumb for 10 minutes(8 seconds pressure and 2 seconds rest) on the SP6 acupoint. This procedure should be repeated for the other foot. Dysmenorrheal pain measured two pain assessment tools (VAS, DPT) pre-treatment; immediate post-treatment; 30minutes, 1, 2hours; and 3, 4, 5, 6, 24 hours after the VAS test were added. RESULTS: The results showed significant differences in pain assessments (VAS, DPT) after treatment for subjects of experimental group1 (p<.05) and experimental group2 (p<.05), whereas the between-group comparison found no statistically significant differences. CONCLUSION: This result supports the idea that using two methods could be effective in pain reduction among students who suffered from primary dysmenorrhea.

• 대한물리의학회지
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• 제15권1호
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• pp.123-132
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• 2020

PURPOSE: This study examined the effects of both lower extremities proprioceptive neuromuscular facilitation training with functional electrical stimulation on the balance and gait of stroke patients. METHODS: Ten patients with stroke were divided randomly into two groups of five patients each who met the selection criteria. The training was conducted five times a week, for 60 minutes. The experimental group received both lower extremities proprioceptive neuromuscular facilitation training with functional electrical stimulation while the control group received general physical therapy with functional electrical stimulation. RESULTS: The timed Up-and-Go (TUG) test result was statistically significant after the intervention in the experimental group (p<.041). Berg Balance Scale (BBS) assessment was statistically significant after the intervention in the experimental group (p<.047) and between the experimental and control groups (p<.012). The cadence assessment was statistically significant after intervention in the experimental group (p<.031) and between the experimental and control groups (p<.015). The stride length assessment was not statistically significant after intervention in the experimental group and between the experimental and control groups. Gait velocity assessment was statistically significant after the intervention in the experimental group (p<.031) and between the experimental and control groups (p<.015). CONCLUSION: Both lower extremities proprioceptive neuromuscular facilitation training with functional electrical stimulation had positive effects on the balance and gait of stroke patients.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제33권2호
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• pp.120-127
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• 2011

Purpose: This study was designed to examine whether the use of neuromuscular electrical stimulation (NMES) after mandibular distraction osteogenesis accelerated bone formation and consolidation. Methods: Eight adult dogs underwent mandibular left body osteotomy. After a 3 day latency period, a distraction rod device was activated at a rate of 1.0 mm once per day for 10 days. After the completion of mandibular lengthening, NMES group was treated twice daily with 2 hours of NMES for 14, and 28 days, while non-NMES group did not receive NMES. The distracted segment was evaluated radiolgraphically histologically and than immunohistochemically for osteopontin (OPN) to evaluate new bone formation and consolidation. Results: Radiography, did not demonstrate significantly different images between the group and the NMES group. Histological examination however, showed that the new bone formation 14 and 28 days after distraction was better in the NMES group when compared to non-NMES group. Immunohistochemical analysis demonstrated that the staining intensity of OPN increased more in the NMES group than in non-NMES group during early consolidation. Conclusion: The results of this study demonstrated that the use of NMES can promote bone formation and consolidation.

• 대한임상전기생리학회지
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• 제5권2호
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• pp.47-59
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• 2007

The purpose of this study were to investigate the effects of electroacupuncture(EA) on sensory nerve function in acute hyperglycemia rats. Male Sprague-Dawley rats weighing 250~270 g(8 weeks of age) were used in this study, and the induced hyperglycemia rats were produced by intraperitoneal injection of streptozotocin(70 mg/kg body weight). Only animals with blood glucose levels of 300 mg/dl or higher were used in this study. Animal were divided into two groups: the control group and EA group (n=7 in each group). For EA, two stainless-steel needles were inserted into Zusanli (ST36) which is located at the anterior tibial muscle and about 10mm below the knee joint. Pulsed current(2 Hz, 0.3 ms) were applied to the inserted needle for 20 mim. We measured glucose level, weigh, sensory nerve conduction and somatosensory evoked potential(5EP) before and after injecting streptozotocin, 2 weeks, 4 weeks. The change of blood glucose on EA group trended to decrease compared with the control group and there were significant differences(p<0.05). The body weight of the EA group trended to be reduced compared with the control group and there were significant differences(p<0.05). The amplitude of sensory nerve action potential on EA group to increase compared with the control group and there were significant differences(p<0.05). There were no significant differences in SEP. These results suggest that EA has beneficial effect on diabetic neuropathy and this effect may be related in part with prevention of hyperglycemia.