• 제목/요약/키워드: 신경생리학

검색결과 154건 처리시간 0.021초

신경근전기자극이 흰쥐 골격근의 미세구조에 미치는 영향 (Effect of Neuromuscular Electrical Stimulation(NMES) on the Ultrastructure of Skeletal Muscle in Rats)

  • 박장성;박천만
    • 대한임상전기생리학회지
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    • 제1권1호
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    • pp.57-72
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    • 2003
  • This study conducts electrical stimulation to male white rat of Spargue-Dawley which is 7 weeks, has the weight of 240 g and is seemingly healthy for one or two weeks by means of neuromuscular electrical stimulator in order to examine the effects of neuromuscular electrical stimulation on its gastrocnemius, measures change of weight of gastrocnemius, serum and enzyme activity and then obtains the following conclusions. There is little difference in AST and CPK of weight and serum of gastrocnemius after one or two weeks of conducting neuromuscular electrical stimulation in all experimental groups. On the one hand, as a result of histochemical observation, NMES I group showed hypertrophy of perimysium and increase of sectional diameter of muscle fiber compared to comparison group, but NMES II group showed a similar result to comparison group. When ultrasubstructure was observed under electron microscope, I-type muscle fiber of NMES I group showed well-arranged mitochondria and it was similar to comparison group. II-type muscle fiber showed a large quantity of glycogen granules within sarcoplasmatic and the extension of luminal of T-tubule. I-type muscle fiber of NMES II group had small mitochondria and showed the vacuolar degeneration of mitochondria and extended T-tubule. II-type muscle fiber showed the extension of agranule cytoplasma reticulum with T-tubule and the reduction of amount of glycogen granule within partial sarcoplasmatic.

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외이경혈자극과 경피신경전기자극이 체성감각에 미치는 영향 (Effects of TENS & Auricular of Somatic on Experimental Pain Threshold)

  • 천진성;김경희;김서희;김지혜
    • 대한임상전기생리학회지
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    • 제2권2호
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    • pp.39-49
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    • 2004
  • The purpose of this study were to examine the effect of high intensity, low frequency transcutaneous electrical nerve stimulation at auricular acupuncture points on experimental pain threshold measured at the wrist and to determine the changes in effect over time. Forty-two healthy adult men and women were assigned randomly to one of three treatment groups. Group 1(n=15) received TENS to appropriate auricular points for wrist, Group 2(n=12) received TENS to wrist, and Group 3(n=15) received no TENS. We measured experimental pain threshold at the wrist after an electrical stimulus during one pre-treatment and three post-treatment time periods. Group 1 and 2 showed stastically significant increase(p<0.05) in pain threshold after treatment whereas the Group 3 did not. Group 1 showed a significant increase in pain threshold than Group 2. These results suggest that high intensity, low frequency TENS applied to appropriate auricular acupuncture points can increase pain threshold.

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백서에서 두개전기자극에 의한 척수신경원 흥분성의 변화 (The Change of Spinal Neuron Excitability by Cranial Electrostimulation(CES) in Rats)

  • 정대인;이정우;김태열;김영일
    • 대한임상전기생리학회지
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    • 제2권3호
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    • pp.37-49
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    • 2004
  • The purpose of this study was to determine the effect of spinal motor neuron excitability by cranial electrostimulation(CES). The fifteen Sparague-Dawley adult male rats were assigned to the three groups; GroupI(control), GroupII(low rate CES), GroupIII(high rate CES). Spinal motor neuron excitability was measured to use a computerized H reflex. The results of this study was as follows; M latency, M amplitude and H latency were no significant difference in all groups on repeated measured ANOVA(p>.05) but low rate CES and high rate CES groups were lower than ether group in comparative measurement of H amplitude and Hmax/Mmax ratio(p<.05). These results lead to the conclusion that spinal neuron excitability was influenced by CES. These results suggest that CES had the capability to lower spinal motor neuron excitability used synaptic blockade in spinal segment.

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신경근전기자극에 의한 경직근의 최대 등척성 수축력 변화 (Change of the Maximal Isometric Contraction to the Spastic Muscle by NMES)

  • 임상완;이정우;김태열;송명수;최은영
    • 대한임상전기생리학회지
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    • 제2권3호
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    • pp.25-35
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    • 2004
  • The purpose of this study was compared to MTICs(maximal tolerated isometric contraction), decrement and recovery. For this, using isokinetic exercise analysis device(Biodex Medical Systems Inc., Biodex System 3PRO, USA), low rate(20 Hz) and high rate(100 Hz) NMES(neuromuscular electrical stimulation) were applied to the quadriceps muscles of fifteen patients with spastic hemiplegia caused by lesions in the central nervous system. The results were as follows: 1. It was shown to fast decrement in the middle of phase at low rate NMES and to slow decrement of MTIC response at high rate NMES(p<.01). 2. It was shown to fast recovery at high rate NMES and to slow recovery at low rate NMES in recovery tendency of MTIC(p<.01). These conclusions suggest that NMES of high rate caused to slow fatigue and fast recovery different from low rate NMES.

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족하수를 동반한 비골신경마비의 환자 1례에 대한 한의학 복합치료 증례보고 (Case Report of Peroneal Nerve Palsy with Foot Drop Treated with Complex Korean Medical Treatment)

  • 김민수;이지영;염승룡;권영달
    • 동의생리병리학회지
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    • 제30권5호
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    • pp.360-365
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    • 2016
  • The purpose of this study is to suggest a possibility of the Korean medical treatment in patient with peroneal nerve palsy, and to suggest importance of differential diagnosis of foot drop. Peroneal nerve pasly was diagnosed by lumbar spine magnetic resonance imaging(MRI) and electromyogram(EMG). The patient was treated with acupuncture, herbal medicine, bee-venom acupuncture and moxibustion from March 7th to May 2nd. We measured Numerical Rating Scale(NRS), Range of Motion(ROM) of the ankle, and observed the change in body temperature using Digital Infrared Thermal Imaging(DITI). After received Korean medical treatment, the patient showed improvement in all the scales mentioned above. The result showed that Korean medical treatment is effective in peroneal nerve palsy before operation.

한의학에서 신경정신과 질환의 증례논문 동향분석 (Review of Case Reports of Neuropsychiatry Disease in Oriental Medicine)

  • 허은정;한창현;김우영;박상영;전원경
    • 동의생리병리학회지
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    • 제25권4호
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    • pp.708-714
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    • 2011
  • This study was aimed to review the trend of case reports of neuropsychiatry disease. The case reports were collected by retrieving Journal of Oriental Neuropsychiatry and analyzing period were from 1990 to 2010. We analyzed them for publish year, research institution, patients, sorts of diseases, pattern identification diagnosis, instrument, treatment period, sorts of treatments, and treatment with western medicine. We analyzed 142 case reports and there were many kinds of neuropsychiatry diseases and instruments that were evaluated the process. The reserchers used various treatment with oriental medicine. However, the number of case reports have decreased since the year of 2008. Most of the research institutions were university and general oriental medical hospital and the portion of private hospitals was only 2.11%. For the development of practical clinical trial of oriental medicine, we needs more qualifying case report. We hope more reserchers for psychiatry disease of oriental medicine will be interested in the publication of case report and this will serve to produce advance of oriental medicine.

신경근전기자극에 의한 대퇴사두근의 최대 등척성 수축력 및 피로도 변화 (Changes of Maximal Isometric Contraction and Fatigue of Quadriceps Femoris Muscle by NMES)

  • 정성관;이정우
    • 대한임상전기생리학회지
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    • 제2권1호
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    • pp.49-57
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    • 2004
  • The purpose of this study was to determine the effect of muscle contraction torque and muscle fatigue by low-frequency PC. In this article, We would like to experiment on electrical stimulation, determine optimal forms of stimulation setting. We used normal fourteen subjects(seven women, seven men) without neuromuscular disease and all subjects participated in the 3 session. Torque was measured using a computerized Kin-Com dynamometer for MVIC, MIC, Fatigue tests. The following results were obtained; 1. Torque of man were significantly higher than women in the MIC test(p<.05). 2. Torque of women, man were significantly decreased in the Fatigue test(p<.001). Between woman and man groups were significant difference(p<.05). These results lead us to the conclusion that muscle fatigue was influenced by PC, fatigue of women was higher than man. Therefore, A further studies concerning the electrical stimulation should consider differences between sexes in response to treatment and could enhance the development of the most effective treatment regimens.

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신문 반응점에 적용한 외이 경피신경전기자극이 압통각 및 촉각역치에 미치는 영향 (Effects on Pressure Pain and Tactile Threshold by Auricular TENS at Shenmen Point)

  • 정대인
    • 대한임상전기생리학회지
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    • 제2권1호
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    • pp.59-70
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    • 2004
  • The purpose of this study were to determine the changes between pre, during, intermed, post of each two groups of 16 persons and to compare the effect of transcutaneous electrical nerve stimulation(TENS) at shenmen of auricular point on experimental pressure pain and tactile threshold measured at both ulnar styloid process and medial malleoli. Sixteen healthy adult men and women, aged 20 to 28 years, were assigned randomly to eight of one groups. Control group received TENS to exception of auricular point. Experimental group received TENS to shenmen of auricular point. Experimental pressure pain and tactile pain threshold at the both ulnar styloid process and medial malleoli was determined with algometer and von frey filament before 10 minute, during 10 minute, intermediate and post 30 min of treatment. In pressure pain and tactile threshold showed a statistically significant increase(p<0.05) ipsilateral and contralateral of treatment group. These results suggest that TENS at shenmen of auricular point has the capability to higher pressure pain and tactile threshold in whole body.

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근막통증후군에 대한 경피신경전기자극과 간섭전류치료의 효과 비교 (Effects of Transcutaneous Electrical Nerve Stimulation and Interferential Current on Myofacial Pain Syndrome)

  • 김명종;이준희;최원호
    • 대한임상전기생리학회지
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    • 제2권1호
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    • pp.1-8
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    • 2004
  • This study was conducted to assess the effect of transcutaneous electrical nerve stimulation(TENS) and interferential current(IFC) in the patients with myofascial pain syndrome(MPS) on upper trapezius. Twenty patients with MPS on upper trapezius was assigned randomly to TENS group(n=10), IFC group(n=10). In TENS group, TENS was applied to the trigger point. In IFC group, IFC was applied to the trigger point. Duration of treatment was 2 weeks. Effects were assessed before treatment, post treatment by visual analogue scale(VAS), and pain rating score(PRS). Significant change of VAS was noticed in TENS group and IFC group. Significant change of PRS was noticed in TENS group and IFC group. IFC groups were significantly higher than TENS group that of the VAS and PRS. These result showed that IFC is effective treatment method for pain control in patients with MPS.

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슈밤머담의 개구라 해부학과 뢰벤훅의 정충관찰의 문제

  • 배선복
    • 한국과학기술학회:학술대회논문집
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    • 한국과학기술학회 2015년도 후기 학술대회
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    • pp.313-326
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    • 2015
  • 데카르트는 사후에 출간된 1662년 "인간론"에서 자동기기의 유압체계모델을 이용하여 인간신체의 신경기능과 근육운동에 대하여 기계론적 설명을 제시하였다. 이것은 바로크 과학기술의 자동기기의 유압체계를 모델로 근육운동이 동물영혼에 의한 신경 전달로 진행된 것을 보여준 실험이었다. 근육운동은 동물영혼에 의한 신경 전달로 진행될 때 이를 기계론적으로 잘 설명될 수 있다고 본 데카르트의 동물영혼에 관한 견해는 출간 이후 3년 만에 네덜란드 자연학자, 해부학자, 현미경학자, 철학자 슈밤머담(Jan Swammerdam 1637-80)이 도전하였다. 그는 1664년 12월 8일 보르흐 앞에서 마취 없이 살아있는 개구리의 심장을 해부하고 두뇌 제거하는 전극실험으로 개구리의 근육운동이 데카르트가 가정하는 동물영혼과는 무관하다는 것을 보여주므로 반박하였다. 슈밤머담은 이 실험 이전에도 이미 라이덴 대학에서 여러 가지 실험으로 명성을 쌓았고 이 실험으로 해부학과 생리학의 출발을 알렸다. 뢰벤훅은 1673년 270배 확대 렌즈를 측정 대에 설치하여 눈에 가까이 갖다 대 고착시킨 첫째 동물이라는 뜻의 박테리아(${\pi}{\rho}\acute{\omega}{\tau}o$ ${\zeta}\acute{\omega}o{\nu}$)를 관찰하였다. 대학에서 전공하지 않았다는 비전문가로서 뢰벤훅이 이 연구에 뛰어들게 되는 것은 바로크 과학기술문명에 중요한 의미를 지닌다. 그라프는 그해 4월 왕립학회에 그가 빗물이나 연못물에서 채취하여 관찰한 미생물을 1677년에 아니말쿨레스(animalcules)라 불렀다는 것을 알렸고 이 관찰은 나중에 왕립학회 검증으로 확증되었다. 뢰벤훅이 명성을 얻게 된 것은 그라프가 그를 학문적으로 이끌어주었기 때문이다. 뢰벤훅에서 광학수업을 받은 하르췌커는 1694년 현미경으로 인간정액을 관찰하는 동안에 하르췌커는 정액 내에 수많은 아니말쿨레스로서 호문쿨리(homunculi)가 살고 있는 것을 보고 그 존재를 요청하였다. 하르췌커는 정규 학문과정에서 성장한 전문가로 뢰벤훅에서 렌즈닦는 기술을 습득하므로 정액주의 운동의 첨단에서 주목을 받게 되었지만 대중적 인기에 영합하였다. 이 발표는 17세기 후반 슈밤머담과 뢰벤훅이 실험철학에 기초한 곤충과 동물 및 미생물 세계의 연구 성과를 과학과 윤리 혹은 신학과의 상보적 관점에서 개관하고, 이들 연구방법을 이신론과 수사학의 입장에서 해명하고자 한다. 17세기 후반에 곤충학의 대가인 슈밤머담과 하르췌커에서 동물생성의 문제에 이신론의 물음은 물질과 정신과의 관계를 해명하려는 과학과 신학과 철학의 경계의 물음이다. 이 경계에서 이신론의 수사학적 접근은 개별분과에서 해결하지 못한 중요한 아포리아를 풀어가는 인문학적 역할에 기여를 할 수 있다.

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