• 건강소식
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• v.34 no.9
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• pp.18-19
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• 2010

현대인들의 고질병이라 불리는 역류성 식도염, 특히 스트레스에 시달리고 잦은 회식으로 인한 술자리와 불규칙한 식생활을 가진 직장인들에게서 잘 발생한다. 보통 만성이기 때문에 만성식도염이라고도 부른다. 역류성 식도염은 여성보다는 남성에게서 더 많이 발병한다. 음주와 흡연이 그 원인으로 지목되고 있다. 역류성 식도염에 대해서 알아본다.

• 건강소식
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• v.39 no.9
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• pp.22-23
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• 2015

60대 자영업자 A씨는 언제부턴가 식사를 하고 나면 씁쓰름한 신물이 식도를 역류해 올라왔다. 어떤 때는 음식물이 넘어와 되새김질을 하기도 했다. 상복부가 쓰리고 가슴 통증이 생겨 병원을 찾아 검사한 결과 '역류성 식도염' 진단을 받았다. 역류성 식도염은 잘못된 식습관에서 비롯되기도 하지만 A씨처럼 나이가 지긋한 경우엔 위 괄약근 조직이 약해져 나타난 것일 수 있다.

• Journal of Chest Surgery
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• v.40 no.10
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• pp.711-714
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• 2007

Phlegmonous esophagitis is a disorder in which bacterial infection occurs in the submucosal and muscular layers of the esophagus. This malady is very rare and it is usually associated with high mortality. A 69-year-old male was admitted with chest pain and fever he'd experienced for 7 days. The chest computerized tomography scan revealed mediastinal widening, circumferential esophageal thickening, an air shadow along the esophagus and right pleural effusion. Drainage and debridement of the mediastinum and primary repair of the perforated esophageal muscular layer through a right thoracotomy was done immediately. Further surgical treatment was not performed. He had a good oral intake without dysphagia or esophageal leakage at discharge.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.11 no.2
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• pp.103-109
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• 2008

Purpose: Children with esophagitis express a variety of nonspecific symptoms and signs depending on their age, and diagnosis is limited because gastrointestinal endoscopy (GFS) and biopsy are difficult to perform. The aim of this study was to examine the prevalence of esophagitis in children with upper abdominal pain, to determine the necessity of esophageal biopsy, and to evaluate the associated risk factors. Methods: We reviewed 266 pediatric patients with upper abdominal pain who underwent history-taking, physical examination, and GFS with esophageal and gastric biopsies between January 2006 and December 2007. Esophagitis was confirmed on biopsy. We analyzed the risk factors for histologic esophagitis and the necessity of esophageal biopsy. Results: The prevalence of esophagitis was 19.9% (53/266 patients). The sensitivity and specificity of endoscopic diagnosis were 41.5% and 77%. Of 53 patients with histologic esophagitis, reflux esophagitis was seen in 50 patients, eosinophilic esophagitis was seen in 2 patients, and esophageal candidiasis was seen in 1 patient. Vomiting was a significant factor in patients under 8 yr of age (p<0.05). H. pylori infection was documented in 41.5% of patients with histologic esophagitis, compared with 58.5% of patients not infected with H. pylori (p<0.05). The possibility of histologic esophagitis was higher in patients with H. pylori infection (OR 2.5, 95% CI 1.2544 to 4.8286) and in those who visited in the spring (OR 2.5, 95% CI 1.2544 to 4.8286). Conclusion: We believe esophageal tissue biopsy should be performed in pediatric patients with upper gastrointestinal symptoms who are undergoing GFS and stomach tissue biopsy, especially preschoolers and H. pylori-infected children in the spring.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1991.06a
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• pp.35-35
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• 1991

식도이물은 대부분 상부식도에 위치하며 식도경술로 제거가 용이하지만 식도 점막내 매복된 이물이나, 식도경술의 합병증으로 인한 천공에 의하여 위급한 종격동염을 유발하는 경우가 있다. 이러한 종격동염은 하부식도에 위치한 이물 특히, 날카롭거나 표면이 불규칙하며 큰 경우에 유발하기 쉬우므로 초기에 개흉술을 통한 제거 또는 배농술 등의 적극적인 치료가 필요하다. 저자들은 1980년부터 1990년까지 10년간 본원에서 식도이물 제거술후 종격동염이 발생되어 개흉술 또는 배농술을 시행 받은 4례(틀니 1례, 칫솔 1례, 조개 껍질 1례, 생선 가시 1례)를 문헌고찰과 함께 보고하는 바이다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1979.05a
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• pp.10.4-10
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• 1979

The cause of esophageal cancer is still unknown in the majority of patients, but pre-existing diseases of esophagus related to the development of cancer were reported by many authors: e.g. lye stricture, achalasia, Plummer-Vinson syndrome, dietary and alocholic habbits etc. Recently the authors had experienced one case of esophageal cancer with complaint of dysphagia, developing at the site of lye stricture, which was diagnosed by the esophagogram and esophagoscopic biopsy.

• Journal of the Korea Convergence Society
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• v.12 no.5
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• pp.255-266
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• 2021

This descriptive survey aimed to investigate the health promotion behaviors of patients with reflux esophagitis and identify the factors influencing it using the health promotion model. The survey was conducted with 178 outpatients diagnosed with reflux esophagitis at C university hospital. Data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation, and multiple regression using SPSS win ver 20. We found that alcohol consumption, BMI, perceived benefit, internal control level, and perceived health status of the patients are significant factors influencing health promotion behavior. The explanatory power was 49%. Therefore, this study is consistent with previous studies that elucidated that changing lifestyle behaviors and obesity control are necessary to alleviate reflux esophagitis. Based on these findings, we propose to develop and apply an educational program for evaluation.

• 건강소식
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• v.36 no.5
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• pp.20-22
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• 2012

중소기업에 다니는 40대 중반의 남성은 얼마 전부터 종종 가슴이 화끈거리는 불쾌한 통증과 함께, 목과 가슴 사이에 복숭아씨가 걸려있는 듯한 답답함을 느꼈다. 혹시나 심장에 이상이 있는 것이 아닌지 검사를 해보았지만, 결과는 정상이었다. 이리저리 알아보다 위액이 역류하는 경우에도 비슷한 증상이 있을 수 있다는 정보를 얻고 소화기내과를 찾았고, 내시경 검사 결과 역류성 식도염 진단을 받았다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1991.06a
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• pp.33-33
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• 1991

부식성 식도염에서 속발한 식도협착의 비외과적 치료법으로 사용되었던 종래의 각종 소식자를 이용한 확장술은 그 효과가 일시적이며 소아에서 시행시 많은 문제점이 있다. 근래들어 관상동맥, 요관, 대장 등의 협착에 사용되어온 balloon Catheter를 이용한 식도 확장술은 비교적 안전하고 효과적이어서 소아나 정도가 심한 식도협착의 치료에 큰 도움을 줄 수 있다. 본 교실에서는 최근 2년간 부식성 식도염 후 속발한 식도협착 6 례를 Balloon catheter 확장법으로 치료하여 아래와 같은 결과를 얻었기에 보고하는 바이다. 1) 전체 6명 중 남자가 4명 여자가 2명으로 평균 연령은 45.7세였다. 2) 부식제의 종류는 가성소다가 5명 초산이 1명이였다. 3) 협착부위는 1례가 경부식도이며 5례가 흉부식도였고 이중 1례는 다발성 협착이 였다. 4) 확장 전 식도조영사진 상 협착부위의 평균 내경은 4.3mm였다. 5) 확장술을 시행한 횟수는 2회에서 5회( 평균 3.5회 )로 확장술이 끝난 후의 평균 내경은 13.5mm였다. 5) 확장술시 3례에서 식도파열이 발생하였으나 보존적 치료법으로 치유되었다.

• Journal of Nutrition and Health
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• v.54 no.3
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• pp.321-333
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• 2021

Purpose: Reflux esophagitis is a disease caused by the reflux of stomach contents and stomach acid etc. into the esophagus due to defect in the lower esophageal sphincter and is currently increasing worldwide. This study was conducted to evaluate the effect of a mixture of Citrus Reticulata and Scutellariae Radix (CS) extract on acute reflux esophagitis in rats. Methods: Rats were divided into five groups for examination: normal group (Normal, n = 8), water-treated acute reflux esophagitis rats (Control, n = 8), tocopherol 30 mg/kg body weight-treated acute reflux esophagitis rats (Toco, n = 8), CS 100 mg/kg body weight-treated acute reflux esophagitis rats (CS100, n = 8), CS 200 mg/kg body weight-treated acute reflux esophagitis rats (CS200, n = 8). The experimental groups were administrated of each treatment compounds and after 90 min, acute reflux esophagitis was induced through surgery. Rats were sacrificed 5 h after surgery. We measured the level of reactive oxygen species (ROS) in serum and analyzed the expression of nicotinamide adenine dinucleotide phosphate, inflammatory, and tight junction-related proteins by western blot in the esophageal tissues. Results: CS administration significantly protected the esophageal mucosal damage due to reflux esophagitis, and the level of ROS in the serum was significantly reduced with CS administration as compared to Control. In addition, CS administration significantly suppressed mitogen-activated protein kinase (MAPK or MAP kinase) and nuclear factor-kappa B (NF-κB) pathways and increased protein expressions of tight junction protein. Conclusion: These results suggest that the CS not only regulates the expression of inflammatory proteins by inhibiting oxidative stress, but also reduces damage to the esophageal mucosa by inhibiting the expression of tight junction proteins.