• 제목/요약/키워드: 시신경

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Toxic Optic Neuropathy Caused by Chlorfenapyr Poisoning (클로르페나피르 음독 후 발생한 독성 시신경병증 1예)

  • Park, Su Jin;Jung, Jae Uk;Kang, Yong Koo;Chun, Bo Young;Son, Byeong Jae
    • Journal of The Korean Ophthalmological Society
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    • v.59 no.11
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    • pp.1097-1102
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    • 2018
  • Purpose: To report a case of toxic optic neuropathy caused by chlorfenapyr ingestion accompanied by central nervous system involvement. Case summary: A 44-year-old female visited our clinic complaining of reduced visual acuity in both eyes for 7 days. She had ingested a mouthful of chlorfenapyr for a suicide attempt 2 weeks prior to the visit. Gastric lavage was performed immediately after ingestion at the other hospital. Her best-corrected visual acuity was finger count 30 cm in the right eye and hand motion in the left eye. Both pupils were dilated by 5.0 mm and the response to light was sluggish in both eyes. A relative afferent pupillary defect was detected in her left eye. Funduscopy revealed optic disc swelling in both eyes. Magnetic resonance imaging of the brain showed a symmetric hyper-intense signal in the white matter tract including the internal capsule, corpus callosum, middle cerebellar peduncle, and brainstem. The patient was diagnosed with toxic optic neuropathy induced by chlorfenapyr ingestion, and underwent high-dose intravenous corticosteroid pulse therapy. Three days later, the best-corrected visual acuity was no light perception in both eyes. Three months later, optic atrophy was observed in both eyes. Optical coherence tomography revealed a reduction in the thicknesses of the retinal nerve fiber layer and ganglion cell and inner plexiform layer in the macular area. Conclusions: Ingestion of even a small amount of chlorfenapyr can cause severe optic nerve damage through the latent period, despite prompt lavage and high-dose steroid treatment.

육성기 및 산란기의 점등관리 요점

  • 박성규
    • KOREAN POULTRY JOURNAL
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    • s.94
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    • pp.90-94
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    • 1977
  • 양계경영에 있어서 점등관리는 닭의 발육, 성 성숙, 산란성과 밀접한 관계를 갖고 있으며 육성기와 산란기의 적절한 점등관리는 닭의 품종, 계통, 연령 및 능력에 못지 않게 중요하다. 광선이 닭에 주어지면 시신경을 통하여 뇌하수체 전엽에 자극이 주어져서 성선자극호르몬이 분비되며 그 호르몬의 작용에 의하여 배란이 일어나게 된다. 이러한 닭의 감광성을 이용하여 산란을 촉진하게 하는 것이 점등관리인 것이다.

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Visually evoked potential in children with mitochondrial respiratory chain defects (소아 사립체 질환에서 시각 유발전위검사의 유용성)

  • Song, Ji Eun;Kim, He Min;Lee, Sang-Chul;Park, Yoon-Gghil;Byeon, Suk-Ho;Lee, Young-Mock;Lee, Joon-Soo;Kim, Heung-Dong
    • Clinical and Experimental Pediatrics
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    • v.52 no.4
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    • pp.471-475
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    • 2009
  • Purpose : Mitochondrial disorders are a clinical entity characterized by diverse symptoms and signs of involvement of various systems. Furthermore, the disorders are known to show ophthalmologic manifestations as well as neurological findings. Visually evoked potential is a sensitive measure to check the integrity of the visual pathway. In this study, we have investigated the value of visually evoked potential in mitochondrial disorders with respiratory chain defects. Methods : Nineteen patients diagnosed with mitochondrial respiratory chain complex I defect as confirmed by spectrophotometric enzyme assay in muscle samples were enrolled for this study. The patients underwent a visually evoked potential study. We classified the results into four groups and compared these with clinical ophthalmologic findings. Results : Among the 19 patients, 14 showed abnormal visually evoked potential findings. Seven patients showed abnormal clinical ophthalmologic findings. All patients with abnormal ophthalmologic findings showed abnormal visually evoked potential findings. Among the 12 patients with normal ophthalmologic findings, seven showed abnormal results in visually evoked potential. Conclusion : Visually evoked potential study could be used as an effective screening tool for mitochondrial disorders to detect ophthalmologic and neurological abnormalities.

Metastatic Germinoma of Spleen from Perichiasmal Area - A Case Report - (원발성 시신경교차 주위 종양으로부터 전이한 비장의 생식세포종 - 1예 보고 -)

  • Shin, Bong-Kyuug;Kim, Min-Kyung;Kim, Han-Kyeom;Chae, Yang-Seok;Won, Nam-Hee;Kim, In-Sun
    • The Korean Journal of Cytopathology
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    • v.12 no.1
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    • pp.61-65
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    • 2001
  • A 20-year-old young man who had undergone treatment for a suprasellar/perichiasmal tumor 2 years before, was presented with a huge palpable splenic mass. A fine needle aspiration cytology from the splenic mass showed dissociated large pleomorphic tumor cells having irregular nuclear outline, coarse chromatin, and one or two macronucleoli, and scattered small lymphocytes in fine granular background. Above cytologic findings were regarded as the characteristics of germinoma. Differential diagnosis from the large cell lymphoma of spleen was emphasized.

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THE CLINICAL STUDY OF THE OPTIC NERVE INJURY AFTER FACIAL TRAUMA (안면골 골절 후 시신경 손상에 관한 고찰)

  • Park, Je-Uk;Yoon, Kyoung-In
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.6
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    • pp.677-680
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    • 2000
  • Orbital injuries are common with facial trauma. Direct injuries to the globe are not rare but it can result in complications such as chemosis, subconjunctival hemorrhage and hyphema. Periorbital trauma or injuries to the extraocular muscles and blow-out fracture may result in lid edema, ecchymosis & ptosis and diplopia or limitation of ocular motion respectively. Indirect injuries to the optic nerve come up without any injuries but its complication is irreversible and severe such as loss of vision. The aim of this study is to review the literature on blindness or ptosis following facial trauma and present the cases of blindness after facial trauma and ptosis after mandibular fracture without specific clinical findings.

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Color Vision의 Physiology와 Color Space

  • 이종문;조순채;이종신
    • Textile Coloration and Finishing
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    • v.3 no.3
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    • pp.57-68
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    • 1991
  • Color vision 현상은 대상물질에 의해서 투과(transmission), 굴절(refraction), 반사(reflection)되어 나오는 광(light)이 망막(retina)에 비칠 때 시신경을 자극하여 뇌에 전달됨으로써 일어나는 하나의 감각현상(sensation)이다. 그러므로 그것은 인간의 감각상태, 광의 종류, 대상물질의 환경조건에 따라서, 즉 시각이 이루어진 그 순간에 인간의 눈이 어떻게 작용 하느냐에 달려있는 복잡한 현상 이다. 그래서 지금까지 발표된 20여개의 색채공간 중 그 어느 것도 인간의 감각량을 똑같이 표현할 수 없었던 것은 사실이다. 모든 자연현상이 그렇듯 인간도 개체마다 모두 다르고 대상물질 및 광에 관련된 너무 많은 요소(Factor)가 색지각 현상에 작용하기 때문에 이의 과학적 표현을 위해서는 단순화 및 normalization의 과정을 거치지 않으면 안되었던 것 같다. 지금까지 발표된 20여개의 color space중, perceptibility에 근거를 둔 유일한 color space인, Munsell color space의 해석에 Spline method 같은 수치 해석적 방법을 쓰지 않으면 안되는 그 이유를 제시하려 한다.

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A Case of Chiasmal Optic Neuritis with Bitemporal Hemianopsia in Multiple Sclerosis (다발성 경화증 환자에서 진단된 양관자쪽반맹을 보이는 시신경교차부염 1예)

  • Kim, Sung-Min;Kim, Min-Jeong;Cha, Jeong-In;Sung, Jung-Joon;Lee, Kwang-Woo
    • Annals of Clinical Neurophysiology
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    • v.8 no.2
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    • pp.199-202
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    • 2006
  • We report a case of chiasmal optic neuritis in a patient who had been diagnosed as multiple sclerosis, and was presented with bitemporal hemianopsia. The brain MRI revealed a high signal lesion with focal enhancement in optic chiasm, and the visual evoked potential functionally supported it. This is the first case of chiasmal optic neuritis in multiple sclerosis with temporally and spatially disseminated lesions.

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