• The Journal of the Korea Contents Association
• /
• v.14 no.12
• /
• pp.854-862
• /
• 2014

Attention deficit hyperactivity disorder (ADHD) students' intellctual defects, learning problems, and poor academic achievements seem to be due to significantly lower intelligence compared to the normal students, but rather the characteristic of inability to pay attention at a given time can be seen as the more attributing reason. In this study, a comparison between the ADHD students and the normal students will be performed using a fMRI analysis in order to differentiate the brain function between the two groups during a working memory task performance and to assess the difference in the activated regions of the brain. Clinical survey examinations and fMRI measurements were performed for a group of 26 elementary students from the Incheon area. The stimulus of fMRI was a working memory. Cartography statistically analyzed parameters and the Statistical Package of Social Sciences using single-sample t-test, two-sample t-test, were analyzed by multiple regression analysis, the statistical significance level was p<0.05 in, respectively. The disproportionate developments could be seen in the ADHD students group such as the frontal cortex, parietal cortex, thalamus, and caudate nucleus, among others. In addition, as some students felt the increase in the difficulty of working memory task performance, the orbitofrontal cortex and the hippocampus were activated, which seems to be the result of an effort for looking for an answer. More types of ADHD students needs to be secured as research subjects, and more stimulations for fMRI experiments should be considered as it would be useful in the overall evaluation of brain function.

• Journal of Korean Society of Environmental Engineers
• /
• v.36 no.12
• /
• pp.821-827
• /
• 2014

The 4major river project has caused changes in flow and water quality patterns in major rivers in Korea including the Nakdong River where several toxicant release accidents have had occurred. Three dimensional hydrodynamic model, the Environmental Fluid Dynamics Code (EFDC), was applied to evaluate the effect of geomorphological change of the river on the advection and dispersion patterns of a conservative toxic pollutant. A hypothetical scenario was developed using historical data by assuming a toxic release from an upstream location. If there is a toxic release at the Gumi Industrial Complex, the toxic material would be detected after 2.22 and 9.83 days at Chilgok and Gangjung weir, respectively, in the new river system. It was estimated that they took at least 12 times longer than those with the river conditions before the project. Effect of relocation of intake towers for Daegu Metro City to upstream of Gumi City was also evaluated using the developed modeling system. It was observed that hydraulic residence time would be increased due to decreased flow rate and thus due to lowered water level. However, peak concentration differences were found to be about 2% lower in both places due to increased dispersion effect after the relocation.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.4 no.1
• /
• pp.68-78
• /
• 1993

The pathophysiology and neural mechanism involved in Tourette's and chronic motor tic disorder are highly controversial. In order to investigate the functional abnormalities of brain. In Tourette's and chronic motor tic disorder, 42 children with Tourette's and chronic motor disorder underwent single photon emission computed tomography(SPECT) using Tc-99m-HM-PAO. The results are summarized as follows : 1) 31.0% (13/42) of this series revealed perfusion defect in cerebral cortex. 2) 4.8% (2/42) revealed perfusion defect in basal ganglia. 3) 4.8(2/42) revealed perfusion defect in thalamus. 4) 16.7%(7/42) showed perfusion defect in cerebellum. 5) The frequency of abnormal perfusion showed no significant difference between tic with and without attention deficit hyperactivity disorder. 6) The frequency of abnormal perfusion showed no significant difference between Tourette's and chronic motor tic disorder. These findings support the hypothesis of a possible involvement of brain dysfunction in the production of Tourette's and chronic motor tic disorder, and quantification of blood flow and co-registration with magnetic resonance imaging will increase the validity of this study.

• Sleep Medicine and Psychophysiology
• /
• v.1 no.1
• /
• pp.76-86
• /
• 1994

Objectives: This research was performed in order to observe the neuropsychological implication and functional anatomical source of event related potentials(ERP) by studying of correlations between event related potentials and neuropsychological tests. Methods: The latency and voltage of P100 of visual evoked potential (VEP), and N120 and P300 of event related potentials were studied in 56 patients and their correlations with neuropsychological tests were computed. Results: The tests showing significant correlation with latency P100 were visual continous performance test(VCPT) and contingent continous performance test(CCPT) without any significant correlation with voltage of P100. In latency of N120 category test and verbal IQ of KWIS showed significant correlation, and in voltage of N120, finger tapping test, VCPT, CCPT and digit symbol test displayed significant correlations. The latency of P300 had significant correlation with trail making A test and Stroop test. In the voltage of P300 significant correlations were shown with trail making B test, digit symbol test and Wechsler memory scale, finger tapping test, stroop test, VCPT and CCPT. Conclusion : N120 may be considered to reflect the function of medial frontal lobe and P300 may be considered to be developed from the subcortical connection of medial temporal lobe, hippocampus, thalamus, basal ganglia and medial frontal lobe.

• The Journal of the Korea Contents Association
• /
• v.10 no.2
• /
• pp.286-294
• /
• 2010

This study was performed to identify the cerebral network associated with sensation through the tickling stimulation, which is distinctive from the rest of other networks processing normal stimulation and to investigate the difference of laughing mechanism which is closely related to tickling using functional MRI(fMRI). A 16 healthy volunteers (mean age: 28.9) on a 3.0T MR scanner during two sensation conditions. Counterbalanced stimulus were presented across the participants, and the stimulation was used block design. Acquired data was analyzed by the statistical parametric mapping (SPM 99). Subject and group analysis was performed. Individual analysis showed the activation of somatic sensation area in both tasks and the tickling sensation test showed more activated area in the Wernicke's area(BA40) compared to the normal sensation. The group analysis result shows that under normal stimulations, both sides of somatosensory cortices(BA 1,2 and 3) were activated and under tickling stimulation, not only the cortices but also those huge activation on thalamus, cingulate gyrus and insular lobe were detected. When the tickling was stopped, significant activations were shown in right cingulate gyrus, left MFG area and left insular lobe. A cerebral area responsible for recognizing tickling sensation was examined and the primitive stimulation such as tickling is much closely related to laugh, which is an important factor for various social activities.

• Fire Science and Engineering
• /
• v.15 no.1
• /
• pp.55-65
• /
• 2001

This paper's purpose is three-folded: modeling the self-regulating fire prevention system, developing a packet of practical fire prevention measures and regulations, and reviewing the applicability of fire insurance system in Korea as a main components of the self-regulating fore prevention system. The so called self-regulating fire prevention system is defined as a grand national fire prevention framework based on and promoted by the vitality and creativeness of the market (or private sector). This drastically contrasts with the existing government-led fire prevention system in Korea. The self-regulating fire prevention system has three grounds: the principle of self-responsibility, the redefinition of the fire service as a public goods, and the principle of self-selection. It seems natural that the self-regulating fire prevention system requires the function of fire insurance institution as a pivoting mechanism providing individual decision makers with a system of incentives, resulting in rational behaviors in the part of each individuals and in the well-balanced fire prevention network in the part of the overall public. In this regard, this pilfer examines the institutions and performance of the fire insurance industry in Korea and reviews the limitation of the industry as an instant replacement mechanism of the current government-led fire prevention system in Korea.

• The Journal of the Convergence on Culture Technology
• /
• v.6 no.3
• /
• pp.193-204
• /
• 2020

According to science technology development, information society has progressed rapidly in the 21st century. Our consciousness and tradition have become entangled in the tide of Westernization. Therefore, the education of Chinese characters was neglected, and Chinese poetry literature was naturally neglected. This led to the abundance of material civilization, however, from the mental aspects, the daily life of modern people became insecure. There is a poet who has lived a lonely life of creation of Chinese poetry in this era. He is a Geasan Kwon Seung Geun(1940~) who writes only poem while being friends with nature. His Chinese poems were revealed through life experiences in nature, which is inspiring sympathy. The origin of his theme is nature. The poetry obtained from nature is rustic simple and pure. Therefore His poems have the style and taste of nature. The Chinese poetry literature of Geasan has been embodied the elements of self-interest, self-satisfaction, self-contentment and living in free at his literatue. On its basis, his Chinese literature has aesthetic boundary of remaining aloofness(自然而然的 超然)·rambling talk, living peacfully and play around with leisure·(閒遠物遊的 閑淡)·deviation rhyme of vividly and beautifully(生趣淸遠的 逸韻) The aesthetic boundary of Chinese poetry of Geasan can be seen as having a depth. This is the aesthetic boundary of Chinese poetry written by this generation in the 21st century.

• Clinical and Experimental Reproductive Medicine
• /
• v.26 no.2
• /
• pp.149-156
• /
• 1999

Steroid hormone is known to cause the dynamic changes of mammalian uterus during reproductive cycle, which are modulated via hypothalamus-pituitary -gonad reproductive endocrine axis. Although there were so many studies about estrogenic regulation of uterine growth and differentiation. There is little information about the effect of estrogen on the expression of various transcription factors involved in gene expression. Thus the present study was designed to demonstrate E induced expression of c-fos, c-jun, hsp25 mRNA in rat uterus. Employing Northern blot analysis, we studied the temporal expressions of c-fos, c-jun, and hsp25 messenger RNAs (mRNAs) elicited by a single 17beta-estradiol (E) treatment in the uteri of bilaterally ovariectomized adult rats. c-fos, c-jun, and hsp25 mRNA levels were increased and peaked at 3h after E administration, and then c-fos and c-jun mRNA levels were rapidly decreased to basal control level while, increased hsp25 mRNA levels were sustained till 12h post E treatment. To test the estrogenic effect on the increase of c-fos, c-jun, and hsp25 mRNA levels, we also examined the effects of antiestrogen (tamoxifen). Pretreatment with tamoxifen effectively blocked the E-induced increase of c-fos, c-jun, and hsp25 mRNA levels at 3h post E treatment. Present results suggest that transient increase of c-fos and c-jun protooncogene mRNA at the early time and simultaneous expression of hsp25 mRNA contribute to the response of uterine tissues to E in adult female rats.

• Development and Reproduction
• /
• v.2 no.1
• /
• pp.21-27
• /
• 1998

The present study was performed to analyze the gene expressions of pituitary adenylate cyclase-activating polypeptide(PACAP) and its receptor in the rat uterus, a candidate for novel extrahypothalamic source and target. The PACAP cDNA fragments corresponding to the common exon region which is found in both the rat hypothalamus and testis were produced from all tissue samples including the rat uterus by reverse transcriptionpolymerase chain reaction (RT-PCR). No PCR product was amplified from the rat hypothalamic, pituitary, ovarian and uterine samples when the 5' primer corresponding to the testis-specific exon 1 region was used, while the predicted size of product was detected from the testis sample. RT-PCR using the uterine RNA and specific primers for the PACAP receptor yielded products with predicted sizes. Transcripts for the rat uterine PACAP receptor were identified as type I isoforms with hip-hop and hip- or hop-type inserts. After pregnant mare's serum gonadotropin (15 IU) treatment of immature rats (day 25), the level of PACAP mRNA was increased in 24 h and 48 h group, and was declined to the lowest in 72 h group. The present study shows the presence of transcripts for PACAP and its receptor isoform in the rat uterus. These finding ssuggest that the uterine PACAP ight act as a novel autocrine and/or paracrine factor via its specific receptors on the reglulation of rat uterine function and physiology during the reproductive cycle.

• Journal of the Korean earth science society
• /
• v.30 no.3
• /
• pp.344-353
• /
• 2009

By measuring the brightness of night sky, we have investigated light pollution around the observatory in the College of Education, Seoul National University. As a result of measuring the extinction coefficient and photometric constants by standardization, in January 28, 2009, the extinction coefficient found to be $k_B$=0.359 and photometric constant was $C_B$=4.397. In March 27, 2009, extinction coefficients were $k_B$=0.896 and $k_V$=0.725, and photometric constants were $C_B$=6.235 and $C_V$=6.027. Brightness of the night sky was measured from east, west, south, and north each by altitude of $20^{\circ}$, $40^{\circ}$, $60^{\circ}$, $75^{\circ}$ and $90^{\circ}$. Data reduction and analysis was based on IRAF. Seeings for the each day of observation were 5.1 and 5.7 arcseconds in January 28 and March 27, respectively. Night sky spanned the magnitude range of $16{\leq}m_V$, $m_B{\leq}18$ We found that the brightness of night sky located at downtown was twice to four times brighter. On these observational conditions, limiting magnitude within 40cm-telescope becomes 11-13 magnitudes. Compared with Jan 28 and Mar 27, night sky brightness of January is 1 magnitude fainter than that of March in B filter.