• Journal of the Institute of Electronics Engineers of Korea CI
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• v.42 no.1
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• pp.1-7
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• 2005

Cluster analysis of microarray data has been often used to find biologically relevant Broups of genes based on their expression levels. Since many functionally related genes tend to be co-expressed, by identifying groups of genes with similar expression profiles, the functionalities of unknown genes can be inferred from those of known genes in the same group. In this Paper we address a novel clustering approach, called seed clustering, and investigate its applicability for microarray data analysis. In the seed clustering method, seed genes are first extracted by computational analysis of their expression profiles and then clusters are generated by taking the seed genes as prototype vectors for target clusters. Since it has strong mathematical foundations, the seed clustering method produces the stable and consistent results in a systematic way. Also, our empirical results indicate that the automatically extracted seed genes are well representative of potential clusters hidden in the data, and that its performance is favorable compared to current approaches.

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.05a
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• pp.36.1-36.1
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• 2011

1차원 양자 구속 효과로 인해 우수한 전하 전송 특성을 갖는 나노선을 차세대 전자소자에 응용하기 위한 일환으로, 실리콘 기판 상에 동일한 실리콘 나노선을 성장하고 이의 미세구조 특징을 분석하였다. 실리콘 나노선은 Au 시드층을 형성한 후 화학기상증착법을 이용한 VLS (vapor-liquid-solid) 공법으로 성장시켰으며, 시드층의 크기에 따른 나노선의 구조 특성을 이미지 프로세싱을 통해 통계분석하였다. 성장된 실리콘 나노선의 결정구조와 성분을 고해상도 투과전자현미경과 EDAX를 이용하여 분석하였으며, 성장 온도 조건에 따른 나노선의 morphology 특성도 실시하였다. 그 결과 Au 시드층의 성분이 나노선과 기판의 계면에서 상당 부분 잔류함과, 성장된 나노선에는 쌍정 결함(twin defect) 등의 결정구조 변화가 수반됨을 알 수 있었다. 또한 금속 시드층의 평균 입도와 성장 온도 및 소스 가스 유량 조절함으로써 실리콘 나노선의 직경과 길이를 최적화 할 수 있었다. 이를 통해 향후 공정 스케일 다운의 한계 상황에 도달하고 있는 반도체 트랜지스터 소자를 대체할 수 있는 나노선 반도체 소자에 대한 공정기술 개발과 이를 이용한 다양한 응용 분야도 동시에 제시할 수 있게 되었다.

• Journal of KIISE:Databases
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• v.41 no.4
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• pp.217-225
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• 2014

Analysis of social media such as Twitter can yield interesting perspectives to understanding human behavior, detecting hot issues, identifying influential people, or discovering a group and community. However, it is difficult to gather the data relevant to specific topics due to the main characteristics of social media data; data is large, noisy, and dynamic. This paper proposes a new algorithm that dynamically selects the seed nodes to efficiently collect tweets relevant to topics. The algorithm utilizes attributes of users to evaluate the user influence, and dynamically selects the seed nodes during the collection process. We evaluate the proposed algorithm with real tweet data, and get satisfactory performance results.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.1
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• pp.61-67
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• 2017

Chia seed (Salvia hispanica L.) originated from Central America is a highly nutritious food containing large amounts of linolenic acid, dietary fiber, and protein. This study investigated the quality properties and antioxidant activities of Sulgidduk prepared with chia seed powder as a functional material. Freeze-dried chia seed powder was replaced with 0, 1, 3, 5, and 7% of rice flour. The addition of chia seed powder did not affect water content, whereas the pH value of the chia seed group decreased as compared to the control. For color measurements, a and b values increased as the amount of chia seed powder increased, whereas L value decreased. Hardness and chewiness of Sulgidduk with chia seed powder were lower than those of the control, whereas springiness of the chia seed group was higher than that of the control. Cohesiveness was not significantly different in all samples. According to retrogradation analysis based on changes in hardness during storage, it was confirmed that addition of chia seed powder inhibited aging of Sulgidduk. Retrogradation of CSP5 was the slowest. Consumer acceptability analysis did not show significant differences in all samples. Total polyphenol and flavonoid contents tended to significantly increase as chia seed content increased. DPPH and ABTS radical scavenging activities of Sulgidduk were also elevated due to addition of chia seeds. From the results, addition of chia seed softened texture, inhibited aging, and enhanced antioxidant activities of Sulgidduk. It is concluded that addition of 5% chia seed powder, which showed high effectiveness for aging, is the most suitable for commercialization.

• Korean Journal of Food Science and Technology
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• v.29 no.2
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• pp.249-254
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• 1997

Stevioside was transglucosylated to improve its sweetness. Eighteen conditions were tested using the tables of orthogonal arrays of $L_{18}\;(2^{1}{\times}3^{7})$. Statistical analysis showed that the transglucosylation rate was significantly affected by temperature, the ratio of co-substrate (maltodextrin) to stevioside, pH, DE of maltodextrin and concentration of stevioside, in their order. Optimum conditions selected for temperature, ratio of co-substrate to stevioside, pH and DE of maltodextrin were $80^{\circ}C$, 1.0, 6.0 and 15, respectively. Glycosyl-stevioside with 68% yield of transglucosylation was produced at the optimum condition and found to have better quality in sweetness than stevioside and rebaudioside A.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.04a
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• pp.20-20
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• 2019

전 지구적으로 학명이 보고된 식물 종은 약 36만종이다. 그 중 종자를 생산하는 관속식물은 310,422종으로 전체 식물종의 85.7%에 달한다(IUCN, 2018). 그리고 2015년 Primely Forest Organization (PFO)에서는 야생식물의 80%가 산림 내에 서식한다고 밝혔다. 식물이 인류에게 주는 다양한 이로움은 인류의 생존과 복지증진에 막대한 영향을 미친다. 2016년 State Worlds Plants (SWP)에 따르면 인류가 현재까지 이용하는 식물종은 31,128종으로 알려져 있다. 이중 약용으로 17,810종, 식량으로 5,538종을 유용하게 이용하고 있다. 하지만 현재 전 지구적 생물멸종속도는 산업혁명 이전 보다 약 1,000배정도 빠르게 진행이 되고 있다(Science, 2017). 이에 전 지구적 생물다양성보전을 위해 생물다양성 협약, 지구식물보전전략 등이 지속적으로 발효 이행되고 있다. 시드볼트는 이러한 보전전략을 이행하기 위해 적합한 시설이다. 우리나라도 노르웨이와 전 세계적으로 2곳뿐이 없는 시드볼트를 가지게 되었다. 우리의 시드볼트는 전 지구적 재난과 재앙에 대비해 야생식물종자를 안전하게 영구 저장하는 시설이고, 우리나라는 봉화군에 위치한 국립백두대간수목원 내에 200만점 저장 규모로 조성이 되어 있다. 현재 국내 외 수집 수탁종자 48,327점이 안전하게 저장이 되어 있다. 국내 23개 종자관련 기관, 단체, 개인과 카자흐스탄 등 해외 3개국 6개 기관이 야생식물종자의 영구저장을 요청하였다. 앞으로 시드볼트는 통일시대에 대비하여 지구적 야생식물종자 저장의 컨트롤타워 역할과 종자연구의 중심기관으로 발돋움 할 것이다. 이에 따른 목표로 2050년까지 백두대간 글로벌시드볼트(BGSV)는 전세계 식물종의 13%, 40만점을 저장할 것이다. 특히 종자연구부분에서는 현재 종 맞춤형 활력검정시스템개발, 분류군별 장기저장 특성분석, 장기저장 종자수명예측 등을 고도화하여 한반도 야생식물 종자정보 플랫폼 구축, 고대 매장종자 보전 모델링 연구, 지구 종자연구 브릿지 구축 등으로 개발, 발전시킬 것이다.

• The Korean Journal of Food And Nutrition
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• v.30 no.2
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• pp.236-242
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• 2017

Chia (Salvia hispanica L.) seed, originated from Central America, is a nutritious food especially rich in dietary fiber and protein. In this study, we investigated the quality and sensory characteristics of Yanggang with chia seed powder (CSP). Red bean paste was replaced with CSP at 0% (Control), 1% (CSP1), 2% (CSP2), 3% (CSP3) and 4% (CSP4). The pH values of chia seed Yanggang tended to decrease from Control (6.84) to CSP4 (6.67); whereas, the moisture contents of Yanggang samples tended to increase. The soluble solid contents of CSP4 were the highest ($3.33^{\circ}Bx$), as compared to the Control which showed the lowest values ($2.77^{\circ}Bx$). In the CSP-added groups, the L-value (lightness), a-value (redness) and b-value (yellowness) were increased, while the ${\Delta}E$ (total color difference) was decreased, as compared to the control group. Hardness and springiness were both increased from control ($49.77g/cm^2$ and 464.80%, respectively) to CSP4 ($72.21g/cm^2$ and 532.43%, respectively). However, cohesiveness decreased from control (47.41%) to CSP4 (37.34%). Chewiness and adhesiveness showed no significant group-wise difference (p<0.05). Total polyphenol content ranged from 7.23 to 10.73 mg GAE/100 g, with a lower ABTS $IC_{50}$ of the CSP-added groups than that of the control group. Samples from the CSP-added as well as Control groups showed no significant differences among all items on the sensory evaluation test, except flavor. The results indicated that CSP had significant effects on the soluble solid contents and texture of Yanggang. Thus, the addition of 2% of CSP is desirable for making Yanggang.

• Applied Chemistry for Engineering
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• v.22 no.1
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• pp.1-14
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• 2011

Water is the most precious resource to human being, but it is polluted by different organic compounds. Organic matter (OM) in aqeous solutions is one of the important parameters of concern for human and environmental impact, and thus, it is essential to better characterize specifically targeted organic matter in aggregated and individual level of concentrations. This review presents different analytical tools and protocols to investigate detailed properties and characterization. Physical, chemical and biological aspects of OM are envisaged in terms of traditional and advanced measurement methods.

• Korean Journal of Plant Resources
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• v.34 no.5
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• pp.478-490
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• 2021

We aimed to generate basic breeding data for melon (Cucumis melo L.). A total of 219 melon accessions conserved at the National Agrobiodiversity Center (NAC) in Rural Development Administration (RDA) were used in this study, of which 72 (33%) were collected from India. The majority of accessions showed orange (42%) and white (36%) flesh color. In addition to phenotypic evaluations, the accessions were genotyped using a molecular marker for the carotenoid biosynthesis gene CmOr. DNA fragments of the expected size were amplified in 205 out of 219 accessions. Digestion of the PCR products with HinfI restriction endonuclease showed 100% concordance between phenotype and genotype in green-fleshed accessions, but 98%, 97%, and 80% concordance in orange-, white-, and creamy-fleshed accessions, respectively. Sequence analysis revealed single nucleotide changes in the three positions of SNP1, SNP2 and SNP1int in the CmOr gene among accessions. These newly found alleles suggest that there are multiple mechanisms in determining fruit flesh color in melon. Also, the phenotype data of diverse accessions obtained in this study will be a valuable source for melon breeding.

• Journal of Life Science
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• v.20 no.4
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• pp.467-473
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• 2010

Gangliosides are a major component of the plasma membrane of mammalian cells, which are directly involved in a variety of immunological events, including cell-to cell or cell-to-protein interactions. In this study, we investigated whether gangliosides, sialic acid-containing glycosphingolipids, are related to rejection during the xenotransplantation of NIH-miniature pig livers and hearts to humans. Both high performance thin-layer chromatography and immunohistochemistry analyses revealed that the expression of gangliosides in the liver tissue of NIH-miniature pigs was higher than that in the heart. Gangliosides GD3, GD1a, GD1b, GT1b and GQ1b were observed in both the liver and heart, whereas GQ1b was detected only in the liver, indicating that the ganglioside expression profiles are tissue specific. Moreover, other ganglio-series gangliosides, including GM3, were not detected in the livers and hearts of NIH-miniature pigs. Taken together, these results suggest that gangliosides may play important roles in immune responses in clinical xenotransplants of pig livers and hearts.