• Investigative Magnetic Resonance Imaging
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• v.2 no.1
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• pp.73-82
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• 1998

Purpose : A precise NMR technique for measuring the rate of water exchange and cell membrane permeability across the hepatocyte membrane using liver-specific MR contrast agent is described. Materials and Methods : The rat hepatocytes isolated by perfusion of the livers were used for the NMR measurements. All experiments were performed on an IBM field cycling relaxometer operating from 0.02MHz to 60 MHz proton Larmor frequency. spin-echo pulse sequence was empolyed to measure spin-lattice relaxation time, T1. The continuous distribution analysis of water proton T1 data from rat hepatocytes containing low concentrations of the liver specific contrast agent, Gd-EOB-DTPA, modeled by a general two compartment exchange model. Results : The mean residence time of water molecule inside the hepatocyte was approximately 250 msec. The lower limit for the permeability of the hepatocyte membrane was $(1.3{\pm}0.1){\;}{\times}{\;}10^{-3}cm/sec$. The CONTIN analysis, which seeks the natural distribution of relaxation times, reveals direct evidence of the effect of diffusive exchange. the diffusive water exchange is not small in the intracellular space in the case of hepatocytes. Conclusions : Gd-EOB-DTPA, when combined with continuous distribution analysis, provides a robust method to study water exchange and membrane permeability in hepatocytes. Water exchange in hepatocyte is much slower thatn that in red blood cells. Therefore, tissue-specific contrast agent may be used as a functional agent to give physiological information such as cell membrane permeability.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.4
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• pp.48-56
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• 2022

Controlling the setting time of cementitious materials is one of the most important factors in securing early-age performance of concrete structures. Recently, the use of retarding admixtures, which enable the inhibition of some hydration products to control the securing time due to average temperature rise is suggested. Although various non-destructive evaluation methods have been proposed to evaluate cement hydration and hardening of cement-based materials to overcome the limitations of Vicat needle test, experimental research is still required to use the non-destructive evaluation method with added retarding admixtures. In this study, measurements of electrical resistivity and ultrasonic wave velocity in early-aged cement pastes were performed according to the addition of retarding admixture(tartaric acid). The setting time of the cement pastes was evaluated by obtained rising time of the both non-destructive measurements. As a result, the possibility of evaluating the setting delay in cement pastes was confirmed through comparative analysis with the initial and final setting times by Vicat test. In addition, X-ray diffraction results at the rising time of electrical resistivity showed a key hydration product affecting the setting delay.

• Korean Journal of Food Science and Technology
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• v.22 no.4
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• pp.445-450
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• 1990

Changes in weight, volume and density of petiole tissue of Chinese cabbage during salting and blanching were investigated. Rapid changes in mass and volume occurred within 4 hours during salting in 5% salt solution and the changes were nearly completed after 8h. After salting, the reduction of mass and volume ranged between $22{\sim}27%\;and\;22{\sim}35%$, respectively. Average density of the sample was found to be 0.88g/ml, and increased to 1.020g/ml after salting. Air content of the sample ranged from 0.093 to 0.120ml/ml cabbage, and about 70% of the initial content was expelled from the tissue by salting. The changes of physical properties of the cabbage during steam blanching were similar to those during salting, but their relative values were smaller. A linearization model for physical changes during salting and blanching was proposed.

• Korean Journal of Applied Biomechanics
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• v.12 no.2
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• pp.197-206
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• 2002

The purpose of this study was to investigate the putter head movement during the putting strokes. Highly skilled 5 golfers(less than 3 handicaps) and 5 novice golfers(having no golf experience) participated in this study. A target distance was 3 m. Movements of the putter head were recorded at 60 Hz with two video cameras. The results showed that the novice golfers moved the club significantly longer than the expert golfers(p<.0001). Accoring to a movement time, novice golfers moved their club significantly faster than the expert golfers(p<0.001). Novice golfers could not control the club head effectively, and could not hit the ball correctly. Based on the impact zone movement, sweet spot of novice golfers moved faster(along the line of putt), higher(along the vertical line), and wider(along the side to side line) than that of expert golfers.

• Journal of fish pathology
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• v.25 no.2
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• pp.95-101
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• 2012

The residue levels of sulfadimethoxine (SDM) was studied after oral administration to cultured olive flounder, Paralichthys olivaceus at $20{\pm}1.0^{\circ}C$. The concentrations of SDM in the plasma and liver were determined by HPLC-UV detector after a single dosage of 400 mg/kg body weight. The average recoveries of SDM in spiked samples between 2~50 ppm were 92.24~93.62% for plasma and 88.34~91.90% for liver. Limit of detection for SDM was 0.05 ppm by using this method. Samples were taken at 1 h, 6 h, 12 h, 24 h, 48 h, 72 h, 168 h, 240 h, 336 h and 480 h post-dose. The peak plasma and liver concentrations of SDM, which attained at 1 h post-dose, was $402.64{\pm}59.66{\mu}g/ml$ and $238.18{\pm}54{\mu}g/g$, respectively. Thereafter, it's elimination from both tissues was considerably faster following process of time. Their concentrations of SDM were not measurable at 480 h post-dose. Based on this results, dosage and withdrawal times for SDM could be used when it is prescribed with SDM in olive flounder.

• The Korean Journal of Financial Management
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• v.26 no.3
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• pp.103-138
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• 2009

In this article we examine a unique data set of intraday fair disclosure(FD) releases to shed light on market efficiency within the trading day. Specifically, this paper analyze the response of stock prices on fair disclosure disseminated in real-time through KIND(Korea Investor's Network for Disclosure) on Korea stock exchange during the period from January 2003 to September 2004. We find that the prices of stock experiences a statistically and economically significant increase beginning seconds after the fair disclosure is initially announced and lasting approximately two minutes. The stock price responds more strongly to fair disclosure on smaller firm but the response to fair disclosure on the largest firm stock is more gradual, lasting five minutes. We also examine the profitability of a short-term trading strategy based on dissemination of fair disclosure. After controlling for trading costs we find that trader who execute a trade following initial disclosure generate negative profits, but trader buying stock before initial disclosure realize statistically significant positive profit after two minute of disclosure. Summarizing overall results, our evidence supports that security prices on Korea stock exchange reflects all available information within two minutes and the Korea stock market is semi-strongly efficient enough that a trader cannot generate profits based on widely disseminated news unless he acts almost immediately.

• The Journal of Engineering Geology
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• v.25 no.4
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• pp.587-598
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• 2015

We examined various existing threshold methods for the determination of the first arrival time of acoustic emission (AE), and developed a new variable threshold method that could determine the first arrival time of AE more accurately and more quickly than existing methods. The new method, a modification of an existing threshold method, does not fix the threshold, but applies variable thresholds for the AE signals according to noise analysis. Two- and three-dimensional models were established to test the effectiveness of the new method. It could determine source locations of AE in a two-dimensional model 38.3% more accurately than the pre-existing threshold methods. Its accuracy improvement over the existing methods in a three-dimensional model was about 15.2%. A practical test involved measuring the source locations of AE during three-point bending tests of granite cores. The new method placed the sources closer to the fracture plane than did the pre-existing methods, indicating its superior (and quicker) ability to determine the source locations of AE.

• The Korean Journal of Nuclear Medicine Technology
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• v.13 no.3
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• pp.56-60
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• 2009

Purpose: The various studies and efforts to develop program are in progress in the field of nuclear medicine for the purpose of reducing scan time. The Oncoflash is one of the programs used in whole body bone scan which allows to maintain the image quality while to reduce scan time. When Those applications are used in clinical setting, both the image quality and reduction of scan time should be considered, therefore, the purpose of this study was to determine the criteria for proper scan speed. Materials and Methods: The subjects of this study were the patients who underwent whole body bone scan at the departments of nuclear medicine in the Asan Medical Center located in Seoul from 1st to 10th, July, 2008. The whole body bone images obtained in the scan speed of 30cm/min were classified by the total counts into under 800 K, and over 800 K, 900 K, 1,000 K, 1,500 K, and 2,000 K. The image quality were assessed qualitatively and the percentages of those of 1,000K and under of total counts were calculated. The FWHM before and after applying the Oncoflash were analyzed using images obtained in $^{99m}Tc$ Flood and 4-Quadrant bar phantom in order to compare the resolution according to the amount of total counts by the application of the Oncoflash. Considering the counts of the whole body bone scan, the dosed 2~5 mCi were used. 152 patients underwent the measurement in which the counts of Patient Postioning Monitor (PPM) were measured with including head and the parts of chest which the starting point of whole body bone scan from 7th to 26th, August, 2008. The correlations with total counts obtained in the scan speed of 30cm/min among them were analyzed (The exclusion criteria were after over six hours of applying isotopes or low amount of doses). Results: The percentage of the whole body bone image which has the geometric average of total counts of under 1,000K among them obtained in the scan speed of 30cm/min were 17.6%(n=58) of 329 patients. The qualitative analysis of the image groups according to the whole body counts showed that the images of under 1,000K were assessed to have coarse particles and increased noises. The analysis on the FWHM of the images before and after applying the Oncoflash showed that, in the case of PPM counts of under 3.6 K, FWHM values after applying the Oncoflash were higher than that before applying the Oncoflash, whereas, in the case of that of over 3.6 K, the FWHM after applying the Oncoflash were not higher than that before applying the Oncoflash. The average of total counts at 2.5~3.0 K, 3.1~3.5 K, 3.6~4.0 k, 4.1~4.5 K, 4.6~5.0 K, 5.1~6.0 K, 6.1~7.0 K, and 7.1 K over (in PPM) were $965{\pm}173\;K$, $1084{\pm}154\;K$, $1242{\pm}186\;K$, $1359{\pm}170\;K$, $1405{\pm}184\;K$, $1640{\pm}376\;K$, $1,771{\pm}324\;K$, and $1,972{\pm}385\;K$, respectively and the correlations between the counts in PPM and the total counts of image obtained in the scan speed of 30 cm/min demonstrated strong correlation (r=.775, p<.01). Conclusions: In the case of PPM coefficient over 3.6 K, the image quality obtained in the scan speed of 30cm/min and after applying the Oncoflash was similar to that obtained in the scan speed of 15 cm/min. In the case of total counts over 1,000 K, it is expected to reduce scan time without any damage on the image quality. In the case of total counts under 1,000 K, however, the image quality were decreased even though the Oncoflash is applied, so it is recommended to perform the re-image in the scan speed of 15 cm/min.

• Journal of Korean Society of Transportation
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• v.29 no.4
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• pp.7-15
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• 2011

Emerged in early 1990s, so called 'Quick service' industry that provides faster delivery of small parcels than regular mail service accelerated use of motorcycles. As the economic grows, use of large bicycles (more than 250CC displacement) for leisure purpose has also rapidly increased. Traffic crash data clearly shows the increasing trend in motorcycle crashes. The ratio of motorcycle involved crashes out of total has increased from 5.7% in 2005 to 8.3% in 2008, and similar trend can be found in fatalities ratio as well. In this study, we assess the level of risk when motorcycles operate on motorways by analyzing traffic rule violation ratio, lane change behaviour, driving speed behaviors of motorcycles in Uninterrupted Traffic Flow Facilities and using PC-CRASH simulation we also calculate car shock impulses occurred when an accident happens. Analysis result shows that the motorcycle is different from the car in terms of lane change timing and average speed, and also shows motorcycle drivers tends to conduct more improper driving behavior particularly when traffic is congested. The results from this study could be usefully applied when the law enforcement agent decides whether bicycles shall be allowed to use motorways. The result could be also utilized as fundamental information for further study of bicycles' driving behavior.

• Journal of Broadcast Engineering
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• v.23 no.1
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• pp.115-125
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• 2018

This paper presents a fast partition decision framework for High Efficiency Video Coding (HEVC) Screen Content Coding (SCC) based on machine learning. Currently, the HEVC performs quad-tree block partitioning process to achieve optimal coding efficiency. Since this process requires a high computational complexity of the encoding device, the fast encoding process has been studied as determining the block structure early. However, in the case of the screen content video coding, it is difficult to apply the conventional early partition decision method because it shows different partition characteristics from natural content. The proposed method solves the problem by classifying the screen content blocks after partition decision, and it shows an increase of 3.11% BD-BR and 42% time reduction compared to the SCC common test condition.