• Journal of Veterinary Clinics
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• v.28 no.3
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• pp.323-327
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• 2011

A Jindo dog (8-month-old, intact male) was referred for hind limb lameness on the right side. The dog was diagnosed with a simple femoral fracture by radiological examination. After surgical fixation of the femoral fracture, tramadol: a narcotic-like synthetic analgesic was intravenously administrated for post-operative analgesia. After injection of the tramadol, generalized tonic clonic seizure was immediately occurred in the dog. Seventeen hours later, the dog died despite intensive care. We suspected that tramadol might induce the seizurogenic effect resulted in death. A necropsy was performed to examine the cause of the death. In consequence, the dog was diagnosed as necrotizing meningoencephalitis (NME) based on histopathological examination. We would be concerned that tramadol may be related to seizure activity in the NME patient. From this case, it is known that although tramadol has been proven to be a safe and effective agent for the control of pain in veterinary medicine, it would be carefully used to patient with history of neurological diseases including meningoencephalitis, hydrocephalus, and encephalopathy.

• Korean Journal of Psychosomatic Medicine
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• v.25 no.2
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• pp.129-135
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• 2017

Objectives : Little is known about the influence of urinary incontinence and depression on individual's QOL(Quality of life). We aimed to clarify how the interaction between urinary incontinence and depression influences one's QOL. Methods : A total of 1262 patients were enrolled in this study from April, 2011 to July, 2011. We estimated the severity of depressive symptoms and QOL, using SGDS-K, EQ-5D. We also investigated the morbidity of urinary incontinence for each patient in person or by questionnaire. Comparisons of QOL between groups with or without depression, with or without urinary incontinence were established using t-test, ANOVA and Scheffe's post hoc analysis. The interaction between urinary incontinence and depression was analyzed by each domain of QOL, using multiple regression analysis. Results : Patients with depression and urinary incontinence showed significantly higher EQ-5D scores on every domain of QOL than other patients, which means significantly lower QOL. Patients with depression, no urinary incontinence reported lower QOL, especially in the domain of 'usual activity', 'anxiety' and 'visual analogue scale(VAS)', whereas those with urinary incontinence, no depression showed lower QOL in 'motility', 'usual activities' and 'pain' domain. Statistically significant interaction effects of two diseases were observed in the domain of 'VAS', 'self care' and 'anxiety'. Conclusions : Comorbidity of urinary incontinence and depression showed significantly lower QOL of patients, compared with urinary incontinence or depression respectively, which implies additive interaction effects of the two diseases. Optimal diagnosis and treatment of depression should be emphasized for patients with urinary incontinence.

• Journal of Technology Innovation
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• v.26 no.4
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• pp.199-232
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• 2018

There are increasing needs for understanding and fathoming of business management environment through big data analysis at industrial and corporative level. The research using the company disclosure information, which is comprehensively covering the business performance and the future plan of the company, is getting attention. However, there is limited research on developing applicable analytical models leveraging such corporate disclosure data due to its unstructured nature. This study proposes a text-mining-based analytical model for industrial and firm level analyses using publicly available company disclousre data. Specifically, we apply LDA topic model and word2vec word embedding model on the U.S. SEC data from the publicly listed firms and analyze the trends of business topics at the industrial and corporate levels. Using LDA topic modeling based on SEC EDGAR 10-K document, whole industrial management topics are figured out. For comparison of different pattern of industries' topic trend, software and hardware industries are compared in recent 20 years. Also, the changes of management subject at firm level are observed with comparison of two companies in software industry. The changes of topic trends provides lens for identifying decreasing and growing management subjects at industrial and firm level. Mapping companies and products(or services) based on dimension reduction after using word2vec word embedding model and principal component analysis of 10-K document at firm level in software industry, companies and products(services) that have similar management subjects are identified and also their changes in decades. For suggesting methodology to develop analysis model based on public management data at industrial and corporate level, there may be contributions in terms of making ground of practical methodology to identifying changes of managements subjects. However, there are required further researches to provide microscopic analytical model with regard to relation of technology management strategy between management performance in case of related to various pattern of management topics as of frequent changes of management subject or their momentum. Also more studies are needed for developing competitive context analysis model with product(service)-portfolios between firms.

• Journal of Chest Surgery
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• v.36 no.7
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• pp.497-503
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• 2003

Pulmonary aspergillosis usually results from the colonization of the existing lung lesions by chronic pulmonary diseases, such as tuberculosis. Most cases of pulmonary aspergilloma have been treated surgically for many years because it is a potentially life-threatening disease causing massive hemoptysis. Here we reviewed our results from the last 10 years. Material and Method: We reviewed 31 cases surgically treated from Aug. 1992 to Jul. 2002. retrospectively. This investigation is designed to illustrate the peak age incidence, sex ratio, chief complaints, preoperative study, anatomic location of operative site, postoperative pathologic finding and postoperative complications. Result: The peak age Incidence laid in the 3rd and 4th decade of 20 cases (64.5%). The most common complaint was hemoptysis in 27 cases (87.1%). The 31 cases had a history of treatment with anti-tuberculous drugs under impression of pulmonary tuberculosis. The 19 cases (61.3%) showed the so-called “Air-meniscus sign” on the preoperative chest X-ray. In the 31 cases (100%) on the chest computed tomography. as a preoperative diagnostic modality, positivity was shown in 37.9%, 83.3% was shown on the fungus culture of sputum for Aspergillus, serum immunodiffusion test for A. fumigatus, respectively. The anatomical location of aspergilloma was mainly in the upper lobe in 19 cases (61.3%) and the majority of cases were managed by lobectomy. The postoperative pathologic findings showed that 31 cases (100%) were combined with tuberculosis. The postoperative complications include empyema, prolonged air leakage, remained dead space, postoperative bleeding and these numbers of cases is 3 cases (9.7%), 2 cases (6.45%), 2 cases (6.45%), 1 case (3.23%), respectively. one case was died postoperatively due to massive beeding, and asphyxia. Conclusion: Compared with the previous study, there is no significant difference in results. Preoperative chest computed tomography and immunodiffusion test were more commonly available and showed high positivity. Operations often became technically difficult because of pleural space obliteration, indurated hilar structures, and poor expansion of the remaining lung, which were more prominent in the patients with complex aspergillosis. In such cases, medical treatments and interventional procedures like bronchial artery embolization are preferred. However, cavernostomy is also recommanded with few additional morbidity because of its relatively less invassiveness. Early surgical intervention is the recommended management for patients with simple aspergilloma considering the Row surgical mortality and morbidity in recent days.

• Archives of design research
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• v.15 no.4
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• pp.275-284
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• 2002

To improve the social and economic position of the disabled people and secure their human rights, an integrated society should be buill. To build such a society, an adequate access should be provided to the movement or in using buildings or facilities. The inconveniences from social life on the part of the disabled people might not result from their impairment or disability, but from physical and social barriers in the environment surrounding them. Therefore, it is necessary to reconstruct entire systems of the society as a disabled people-friendly structure in order to remove those barriers, make them stand their own feet in our communities and freely participate in the social activities. This will eventually lead to build a society in which all people including the disabled people can use those facilities in a more convenient way. It is almost impossible for the disabled people to safely and conveniently access to and use facilities and equipments and freely move to their desired places, without any help from others in Korea. Even though, there are currently many disabled people-related convenience facilities, they have been independently built without a connection with other facilities and buildings, thus not greatly useful. Even when convenience facilities have been built, mostly they are superficially set up; therefore, in many cases, the disabled peOple cannot use those facilities. In this. research, I tried a new concept of mobile wheelchair lift design, which the disabled people can operate without restrictions, when using the public facilities. The key to this research was to develop the existing import-oriented simple functional products to a new system with functional safety and high quality orientation. Also, this research aimed at bringing an. import substitution effect, as well as preempting the mobile wheelchair lift market by advancing into overseas markets through application of new image designs in the field of disabled people aid equipments.

• Clinical and Experimental Pediatrics
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• v.50 no.9
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• pp.882-890
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• 2007

Purpose : Preterm very low birth weight infant have high rate of adverse neurodevelopmental sequale. Recently, there have been lots of reports that human umbilical cord blood transplantation ameliorates functional deficits in animal models as hypoxic ischemic injury. This pilot study was undertaken to determine the clinical efficacy and safety of autologous umbilical cord blood cell transplantation for preventing neurodevelopmental sequale in perterm VLBW. Methods : Subjects were 26 preterm infants whose birth weight are less than 1,500 g and delivered under the intrauterine period 34 weeks. Autologous umbilical mononuclear cells (about $5.87{\times}10^7/kg$) were injected to neonate via the umbilical vein on the postnatal 24-48 hour. The therapeutic efficacy was assessed by numbers of nucleated RBC, urinary uric acid/creatinine ratio, concentration of neuron specific enolase (NSE), interleukin 6 (IL6), interleukin-$1{\beta}$ ($IL-1{\beta}$), and glial cell derived neurotrophic factor (GDNF) in serum and cerebrospinal fluid on day 1 and 7. Results : There were no significant differences in the numbers of the nucleated RBC, urinary uric acid/creatinine ratio, concentration of creatine kinase between the transplanted infants and controls. But the nucleated RBC is more likely to be rapidly discharged in the transplanted group. In the transplanted group, the concentrations of IL6, $IL-1{\beta}$, and GDNF were no significant difference between day 1 and 7, although GDNF seemed to be elevated. Serum NSE concentration was significantly elevated after transplantation, but not in CSF. Conclusion : It is suggested that autologous umbilical cord blood transplantation in preterm very low birth weight infant is safe to apply clinical practice. Long term follow up study should be needed to evaluate the potential therapeutic effect of umbilical cord blood transplantation for neuroprotection.

• Geophysics and Geophysical Exploration
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• v.13 no.3
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• pp.219-226
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• 2010

Current earthquake alert notification for immediate post-earthquake procedures for the critical facilities is exclusively dependent on the ground-motion intensity measures observed at the seismic station located within the site. This practice is prune to false notification due to a noise and problems of missing and poor quality records of the seismic station. The credibility of the earthquake alert notification can be enhanced by utilizing the multiple transformed records of the nearby seismic stations at other sites interconnected to the same earthquake monitoring system by a network. The time-domain transformation of the site-response between the seismic stations is implemented by convoluting the nearby records with a pair of forward and inverse FIR filters designed for the site response relative to a seismic basement. The transformed records from the nearby seismic stations can be used to estimate the ground-motion intensity measures missing at the site or to evaluate the data quality along with other various possible applications in the area of geoscience and earthquake engineering.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.1
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• pp.19-25
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• 2020

In frequent pattern mining, the uncertainty of each item is accompanied by a loss of information. AAlso, in real environment, the importance of patterns changes with time, so fuzzy logic must be applied to meet these requirements and the dynamic characteristics of the importance of patterns should be considered. In this paper, we propose a fuzzy utility mining technique for extracting frequent web page sets from web log databases through fuzzy utility-based web page set mining. Here, the downward closure characteristic of the fuzzy set is applied to remove a large space by the minimum fuzzy utility threshold (MFUT)and the user-defined percentile(UDP). Extensive performance analyses show that our algorithm is very efficient and scalable for Fuzzy Utility Mining using dynamic weights.

• Proceedings of the Korea Water Resources Association Conference
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• 2008.05a
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• pp.1639-1643
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• 2008

국내에서의 범람홍수 및 범람으로 인한 제방붕괴 특성은 그 해석상의 어려움으로 인해 주로 과거 범람상황 및 지형도를 통한 경험적 추정 등에 의존해 오고 있는 실정으로 정교한 물리학적 이론에 근거하지 못하였으므로 범람홍수량, 제방의 붕괴폭 등을 정확하게 예측하기에는 미흡한 점이 많았다. 도시하천과 같이 제방 인접한 곳에 주거, 산업시설 등이 밀집하고 있는 지역에서의 제방붕괴로 인한 홍수류의 범람은 막대한 인명 및 재산피해를 발생시키는 큰 재해가 될 수 있다. 본 연구를 통해서 홍수시 제방월류로 인한 제방붕괴 양상을 예측하고 이를 통해 범람유량의 정확한 예측을 통하여 도시하천 제방 계획시 홍수피해와 투자액을 감안한 경제적인 하천 제방단면 결정을 위한 기본자료로 활용될 수 있고, 도시 중요시설물의 입지 선정시 홍수피해에 대한 판단자료로 이용될 수 있을 것이다. 본 연구에서 개발된 모형을 이용하여 Teton 댐, Mantaro landslide 댐, Spirit Lake 장애물 댐 등에 적용하여 개발된 모형의 정확성을 입증하였다. 적용결과 개발된 모형은 기존의 모형과 같은 결과를 나타내어 국내 계산환경에 적용가능함을 보여 앞으로 이용가능성이 큰것을 알 수 있었다. 적용결과 파이핑의 발생위치의 영향은 대체로 파이핑의 위치가 제체의 윗부분에 위치할수록 최대 유출량은 커지는 것으로 나타났으나 Lawn Lake 댐의 경우에는 사면의 식생의 영향으로 다른 결과를 나타내었다. 점착력은 경우에는 점착력이 클수록 유출량의 크기는 감소하는 것으로 나타났으며 마찰각은 최대 붕괴폭의 크기 및 발생시간, 댐의 높이와 폭, 저수용량 등과 유출량이 연관있어 좀 더 많은 계산결과를 이용하여 심도있는 고찰이 요구되었다. 입자의 중간크기, 공극률, 균일성의 경우 적용된 댐들 모두 유사한 결과를 나타내었고 변수들이 커질수록 유출량도 증가하였다. 댐 사면 경사의 경우에는 상,하류 사면 모두 경사가 완만할수록 유출량이 감소하였다. 위의 결과를 통해 개발된 제방붕괴 해석모형은 좀 더 많은 연구와 적용을 통해 개선과 검증이 이루어진다면 국내 제방붕괴해석에 필요한 해석모형이 될 수 있다고 판단되었다.

• Journal of the Korea Institute of Building Construction
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• v.13 no.4
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• pp.321-332
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• 2013

Costs and expenses are intertwined and incurred throughout an entire construction project, even from the pre-construction phase, and each phase has a different impact on the life cycle cost (LCC). However, the cost breakdown structure (CBS) is different in each phase of a building construction project, which makes it hard to reasonably calculate construction cost. For this reason, the boundary conditions were analyzed in this study based on the life cycle cost break structure (LCCBS). In addition, breakdown factors were analyzed based on the boundary conditions to derive a linkage method. The validity of the linkage method was verified through application to actual construction projects. Through the analysis, it was found that the problem of items being left out was reduced by more than 97.2 percent, and the work was done an average of 6 hours faster compared to the conventional method. It is expected that by applying the new LCC system, LCC will be both reduced and calculated in a more efficient manner.