• Title/Summary/Keyword: 수면발생기간

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The Changes of Plasma Catecholamines Concentration during Waking and Sleep in Obstructive Sleep Apnea Syndrome Patients with Systemic Hypertension (전신성 고혈압을 동반한 폐쇄성 수면 무호흡증후군 환자에서 각성시와 수면중의 혈장 Catecholamines 농도 변화)

  • Moon, Hwa Sik;Lo, Dae Guen;Choi, Young Mee;Kim, Young Kyoon;Kim, Kwan Hyoung;Song, Jeong Sup;Park, Sung Hak
    • Tuberculosis and Respiratory Diseases
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    • v.43 no.4
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    • pp.600-612
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    • 1996
  • Background : Recent studies deported that untreated patients with obstructive sleep apnea syndrome had high long-term mortality rates, and cardiovascular complications of these patients clad a major effect on mortality. Several data indicates that obstructive sheep apnea syndrome contributes to the development of diurnal systemic hypertension. But the pathophysiological mechanism of the development of systemic hypertension in these patients is still uncertain. This study was performed to evaluate the possible role of sympathetic nervous system activity for the development of systemic hypertension in patients with obstructive sleep apnea syndrome. Method : 35 patients with obstructive sleep apnea syndrome(OSAS) and 13 Control subjects(control) were included in this study. 21 patients of OSAS were normotensives(OSAS-NBP), and 14 patients of OSAS were hypertensives(OSAS-HBP). Full night polysomnography was undertaken to all subjects. We measured plasma norepinephrine(NE) and epinephrine(EP) concentrations during waking and sleep, using high performance liquid chromatography, in all patients and control subjects. Results : In OSAS, OSAS-NBP and control, plasma NE and EP concentrations during sleep were lowed than during waking(p<0.01). But, in OSAS-HBP, these was no difference between during waking and sleep. Plasma NE concentrations during sleep of OSAS, OSAS-NBP and OSAS-HBP were higher than Control(p<0.05). In OSAS-HBP, daytime systolic blood pressure correlated with plasma NE concentration during sleep(r=0.7415, p<0.01), arid correlated inversely with mean arterial oxygen saturation(r=-0.6465, p<0.05) or arterial oxygen saturation nadir(r=-0.6) 14, p<0.05) during sleep. Conclusion : The sympathetic activity during sleep of obstructive sleep apnea syndrome patients was higher than control subjects. In obstructive sleep apnea syndrome patients with systemic hypertension, there was no diurnal variation of sympathetic activity, and there was correlation between daytime systolic blood pressure and sympathetic activity during sleep. These data suggests that chronic hyperactivity of sympathetic nervous system may contribute to the development of diurnal systemic hypertension in patients with obstructive sleep apnea syndrome.

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The Influence of Obstructive Sleep Apnea on Systemic Blood Pressure, Cardiac Rhythm and the Changes of Urinary (폐쇄성 수면 무호흡이 전신성 혈압, 심조율 및 요 Catecholamines 농도 변화에 미치는 영향)

  • Lo, Dae-Keun;Choi, Young-Mee;Song, Jeong-Sup;Park, Sung-Hak;Moon, Hwa-Sik
    • Tuberculosis and Respiratory Diseases
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    • v.45 no.1
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    • pp.153-168
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    • 1998
  • Background: The existing data indicate that obstructive sleep apnea syndrome contributes to the development of cardiovascular dysfunction such as systemic hypertension and cardiac arrhythmias, and the cardiovascular dysfunction has a major effect on high long-term mortality rate in obstructive sleep apnea syndrome patients. To a large extent the various studies have helped to clarify the pathophysiology of obstructive sleep apnea, but many basic questions still remain unanswered. Methods: In this study, the influence of obstructive sleep apnea on systemic blood pressure, cardiac rhythm and urinary catecholamines concentration was evaluated. Over-night polysomnography, 24-hour ambulatory blood pressure and ECG monitoring, and measurement of urinary catecholamines, norepinephrine (UNE) and epinephrine (UEP), during waking and sleep were undertaken in obstructive sleep apnea syndrome patients group (OSAS, n=29) and control group (Control, n=25). Results: 1) In OSAS and Control, UNE and UEP concentrations during sleep were significantly lower than during waking (P<0.01). In UNE concentrations during sleep, OSAS showed higher levels compare to Control (P<0.05). 2) In OSAS, there was a increasing tendency of the number of non-dipper of nocturnal blood pressure compare to Control (P=0.089). 3) In both group (n=54), mean systolic blood pressure during waking and sleep showed significant correlation with polysomnographic data including apnea index (AI), apnea-hypopnea index (AHI), arterial oxygen saturation nadir ($SaO_2$ nadir) and degree of oxygen desaturation (DOD). And UNE concentrations during sleep were correlated with AI, AHI, $SaO_2$ nadir, DOD and mean diastolic blood pressure during sleep. 4) In OSAS with AI>20 (n==14), there was a significant difference of heart rates before, during and after apneic events (P<0.01), and these changes of heart rates were correlated with the duration of apnea (P<0.01). The difference of heart rates between apneic and postapneic period (${\Delta}HR$) was significantly correlated with the difference of arterial oxygen saturation between before and after apneic event (${\Delta}SaO_2$) (r=0.223, P<0.001). 5) There was no significant difference in the incidence of cardiac arrhythmias between OSAS and Control In Control, the incidence of ventricular ectopy during sleep was significantly lower than during waking. But in OSAS, there was no difference between during waking and sleep. Conclusion : These results suggested that recurrent hypoxia and arousals from sleep in patients with obstructive sleep apnea syndrome may increase sympathetic nervous system activity, and recurrent hypoxia and increased sympathetic nervous system activity could contribute to the development of cardiovascular dysfunction including the changes of systemic blood pressure and cardiac function.

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A Study on the Complex Stage-Discharge Rating Curve Development in Tidal River (감조하천에서 복합 수위 유량관계곡선 개발에 수위-관한 연구)

  • Lee, Sin-Jae;Jung, Sung-Won;Lee, Jin-Won;Park, Sang-Woo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.367-372
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    • 2008
  • 본 연구는 감조하천에서 조위의 영향을 크게 받는 저 평수위의 수위-유량관계곡선식 개발의 한계를 극복하기 위해 조위의 영향을 고려한 다변수 복합 수위-유량관계곡선식을 개발하였다. 곡선식 개발은 수위-수면차-수위차-유량의 관계를 통해 지수형 곡선식을 개발하였다. 여기서 수면차는 조위와 수위와의 차이며, 이때 조석파의 전파시간에 대한 지체시간을 고려하였다. 수위차는 대상 수위관측소의 전 시간과의 수위차이다. 또한 조위에 의해 발생되는 역유량 자료를 이용한 지수형 곡선식을 개발하고자 유량 조정변수를 추가하였다. 개발된 수위-유량관계곡선식을 한강대교에 적용하여 자동유량측정시설에서 측정된 유량자료와 비교 검토한 결과 경향성에서 일치하였으며, (-)유량의 산정도 가능하였다. 분석기간내의 총 유출량 검토 결과 8.3%의 오차를 보여 본 과업에서 제시된 복합 수위-유량관계곡선식의 적정성을 파악할 수 있었다.

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Fundamental Study on the Evapo- transaration Requirements of Patty rice Plant (벼 용수량계획상의 엽면증발량 및 주간수면 증발량에 관한 기초적인 연구)

  • 김철기
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.11 no.2
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    • pp.1651-1660
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    • 1969
  • The purpose of this study is to find out the reasonable amount of evapo-transpiration required for the paddy rice plant during the whole growing season. So. On the basis of the experimental data concerning the evapo-transpiration form 1966 to 1968, the author obtained the follow results. 1) The leaf area index in the densely planted plo is generally higher than that in the conventionally planted one during the first half of growing season So, the coefficient of transpiration in the former plot is somewaht higher than in the latter, and the coefficient of water surface evaporation under the plant cover has the inverse relation between both plots. 2) It is unreasonable that coefficient of evapo-transpiration is applied to the calculation of the evapo-transpiration requirements of each growing stage, because a degree of variation in meteorological factors and in the thickness of the plant growth is involved in it. 3) It is most reasonable that the rate of transpiration and of the water surface evapoation is applied to the calculation of the transpirated amount and evaporated one in each growing stage, because it shows almost constant value in spite of any meteorological conditions in so far as the variety of rice, planted density and control of applying fertilizer are sanme and the disease and blight are negligible. 4) The ratio of the amount of transpiration to the weight of the whole air dried yields has the tendency of decreasing as that of the yields increases having almost constant value despite the amount of pan evaporation; and the value is about 210 when the weight of root parts is included to that the yields. 5) Although the required amount of transpiration during the whole growing season can be calculated with the above ratio, Fig. 7 showing the relation between the amount of transpiration and the weight of the yields is more reasonable and will be convinient to find it. And the requirements of water surface evaporation during the same season can also be directly found witht theweight air dried straw refering to Fig. 8.

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Characteristics of Sleep Apnea Syndrome in the Elderly in a Clinical Setting (나이에 따른 수면무호흡증 임상적 특성의 변화)

  • Shin, Yoon-Kyung;Yoon, In-Young;Hong, Min-Chul;Yun, Yong-Don
    • Sleep Medicine and Psychophysiology
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    • v.12 no.1
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    • pp.39-44
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    • 2005
  • Objectives: Much attention has been paid to sleep apnea syndrome (SAS) in the elderly because of its high prevalence. It is expected that SAS in the elderly has both similarities and differences compared to SAS in the young or middle-aged populations. The aim of this study was to elucidate the characteristics and consequences of SAS in the elderly. Methods: In this study we included 210 young or middle-aged adults between 23 and 59 years (20 women and 190 men) and 65 older adults between 60 and 83 years of age (16 women and 49 men). Respiratory disturbance indices (RDIs) of the study subjects were more than 5 in an overnight polysomnography. They completed the Epworth Sleepiness Scale (ESS) and Pittsburgh Sleep Quality Index (PSQI). Informations about body mass index (BMI), neck, waist, and hip measurements, and blood pressure were obtained. Results: No difference was observed between older adults with SAS (older SAS) and adults aged under 60 with SAS (SAS aged under 60) in RDI, apnea index, % time of oxygen saturation less than 90%, and PSQI. Obstructive apnea index and oxygen desaturation index (ODI) were lower in older SAS. Compared to SAS aged under 60, lowest oxygen saturation and central apnea index were higher in older SAS, but they were statistically not significant. BMI and neck circumference were significantly lower in older SAS compared to SAS aged under 60. Diastolic blood pressure was lower in older SAS compared to SAS aged under 60 with no difference in systolic blood pressure. Older SAS showed lower scores in ESS than SAS aged under 60. Significant correlation was observed between RDI and BMI in SAS aged under 60, but not in the case of older SAS. The relationships between RDI and neck circumference, systolic and diastolic pressure, and ESS were similar. Conclusions: The elderly with SAS were not over-weight and there was no relationship between body weight and the severity of SAS. Also, the behavioral and cardiovascular effects of SAS were not marked in the elderly, which might be partly explained by decreased ODI and relatively higher lowest oxygen saturation in older SAS. The normal aging process, aside from increased body weight, might contribute to the development of SAS in the elderly with modest complications.

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Design and Implementation of Low-power CSD Considering Beacon Period and Channel Scan Time (비컨 주기와 채널 탐색기간을 고려한 저전력 CSD의 설계 및 구현)

  • Kim, Taek-Hyun;Park, Se-Young;Choi, Hoon;Baek, Yun-Ju
    • Journal of KIISE:Computing Practices and Letters
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    • v.16 no.1
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    • pp.50-54
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    • 2010
  • A Container Security Device (CSD) which is different existing RFID Tag strengthens the physical security as mounted inside the container and the information security as encrypts doubly a data. CSD must use the resources efficiently in order to operate with the battery. Therefore, it needs low-power mechanism which repeats the sleep period and channel scan period. However, by adjusting these periods, the trade-off occurs between energy efficiency and network connectivity. In this paper, we implement low-power CSD and resolve this problem by adjusting beacon period and channel scan time. As a result, We guarantee the network connectivity 95% or more and maximum life up to 16 days using common AA batteries.

Discharge estimation using index velocity method in the confluence of rivers affected by backwater (배수영향을 받는 하천의 합류부에서 지표유속법을 이용한 유량산정에 대한 적절성 검토)

  • Hwang Jae Sung;Oh Dong Heon;Cho Sang Uk
    • Proceedings of the Korea Water Resources Association Conference
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    • 2023.05a
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    • pp.307-307
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    • 2023
  • 하천의 합류부는 물의 흐름에 변화가 생겨 수면 변화가 상류에 미치는 배수현상이 나타난다. 또한 한강과 평창강이 만나는 영월 지역의 경우 각 유역 면적이 비슷하기 때문에 홍수 사상에 따라 상호 배수 영향을 주어 수위에 영향을 준다. 그러므로 배수영향기간에는 하천 유량을 산정하는 기존 방법인 수위-유량관계곡선(stage-discharge relation curve)을 이용한 환산 유량은 실제 측정 유량과 차이가 있고, 연속적으로 유속을 직접 측정하여 얻은 유속과 평균유속 간의 관계를 이용한 지표유속법(index velocity method)의 적용에 대한 적절성을 검토할 필요가 있다. 본 연구에서는 강우 사상에 따른 영월군(영월대교) 지점, 영월군(팔괴교) 지점 간 기간별 상호 배수 영향을 검토하여 수위-유량관계곡선식 및 지표유속법을 비교·적용 하였고, 기간별 상하류 유량관계 및 총 유출량 분석을 실시하여 유량산정에 대한 적절성을 검토하였다. 배수 영향 발생 시 지표유속법을 이용하여 산정된 유량을 적용한 결과 상하류 유량 관계 및 총 유출량이 적절한 것으로 확인되었고, 배수 영향 기간에는 지표유속법을 활용하여 유량을 산정하는 것이 타당한 것으로 분석되었다.

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The Effects of the Urinary Incontinence and Quality of Sleep on Fall Efficacy of the Community Dwelling Elderly (지역사회 노인의 요실금과 수면의 질이 낙상 효능감에 미치는 영향)

  • Yun, Eun-Suk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.4
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    • pp.2142-2149
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    • 2014
  • This study was to find out urinary incontinence, quality of sleep and efficacy of fall in the community dwelling elderly and to investigate how the factors were connected to one another. Data were collected between January 3rd and 30th, 2013 from 112 elderly people who aged 65 or older. They agreed to participate in this study sampled among elders assistants in a way of responding to the questionnaire after being read. The study scales were composed of demographic characteristics, urinary incontinence, quality of sleep and efficacy of fall. A total of 45(40.2%) subjects were reported fall experienced. The results showed a positive correlation with urinary incontinence, quality of sleep and efficacy of fall. Multiple linear regression analysis revealed that predictor of efficacy of fall was quality of sleep. A combination of the urinary incontinence and quality of sleep accounted for 9.6% of the efficacy of fall.

Discharge estimation using index velocity method in the confluence of main river and tributary affected by backwater (상호 배수영향을 받는 본류와 지류의 합류부에서 지표유속법을 이용한 유량산정)

  • Hwang, Jae Sung;Cho, Sang Uk;Song, Jae Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2022.05a
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    • pp.438-438
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    • 2022
  • 본류와 지류가 만나는 하천의 합류부는 물의 흐름에 변화가 생겨 수면 변화가 상류에 미치는 배수현상이 나타난다. 또한 한강과 평창강이 만나는 영월 지역의 경우 각 유역 면적이 비슷하기 때문에 홍수 사상에 따라 상호 배수 영향을 주어 상류 수위에 영향을 준다. 그러므로 하천 유량을 산정하는 기존 방법인 수위-유량관계곡선(stage-discharge relation curve)을 이용한 환산 유량은 실제 측정 유량과 차이가 있다. 본 연구에서는 2021년 강우 사상에 따른 영월군(영월대교) 지점, 영월군(팔괴교) 지점 간 수위관측소 수위 비교, 각 지점의 수위관측소 수위와 유량관측소 수위 비교, 각 지점의 수위-지표유속관계를 분석하여 기간별 상호 배수 영향을 검토하였고, 연속적으로 유속을 직접 측정하여 얻은 유속과 평균유속 간의 관계를 이용한 지표유속법(index velocity method)의 적용을 검토하였다. 검토 결과 배수 영향 발생 시 지표유속법을 이용하여 산정된 유량과 수위-유량관계곡선식으로 산정된 유량 간의 차이가 발생하였고, 배수 영향 기간에는 지표유속법을 활용하여 유량을 산정하는 것이 타당한 것으로 분석되었다.

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Analysing the effect of impervious cover management techniques on the reduction of runoff and pollutant loads (불투수면 저감기법의 유출량 및 오염부하량 저감 효과 분석)

  • Park, Hyung Seok;Choi, Hwan Gyu;Chung, Se Woong
    • Journal of Environmental Impact Assessment
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    • v.24 no.1
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    • pp.16-34
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    • 2015
  • Impervious covers(IC) are artificial structures, such as driveways, sidewalks, building's roofs, and parking lots, through which water cannot infiltrate into the soil. IC is an environmental concern because the pavement materials seal the soil surface, decreasing rainwater infiltration and natural groundwater recharge, and consequently disturb the hydrological cycle in a watershed. Increase of IC in a watershed can cause more frequent flooding, higher flood peaks, groundwater drawdown, dry river, and decline of water quality and ecosystem health. There has been an increased public interest in the institutional adoption of LID(Low Impact Development) and GI(Green Infrastructure) techniques to address the adverse impact of IC. The objectives of this study were to construct the modeling site for a samll urban watershed with the Storm Water Management Model(SWMM), and to evaluate the effect of various LID techniques on the control of rainfall runoff processes and non-point pollutant load. The model was calibrated and validated using the field data collected during two flood events on July 17 and August 11, 2009, respectively, and applied to a complex area, where is consist of apartments, school, roads, park, etc. The LID techniques applied to the impervious area were decentralized rainwater management measures such as pervious cover and green roof. The results showed that the increase of perviousness land cover through LID applications decreases the runoff volume and pollutants loading during flood events. In particular, applications of pervious pavement for parking lots and sidewalk, green roof, and their combinations reduced the total volume of runoff by 15~61 % and non-point pollutant loads by TSS 22~72 %, BOD 23~71 %, COD 22~71 %, TN 15~79 %, TP 9~64 % in the study site.