• Journal of Nutrition and Health
• /
• v.35 no.4
• /
• pp.489-497
• /
• 2002

This study was conducted to determine if Mehrabian's eating-related characteristics questionnaire could be effectively applied in predicting obesity and eating disorders among Korean college students by examining the correlations between eating-related characteristics and anthropometry, nutrient intakes, psychological aspects of depression, and personality dimensions. The data were collected from 151 female students in classes of nutrition or psychology in Kyungnam University. Measurements of height, weight and triceps skinfold thickness (TSf) were made by well-trained interviewers, and BMI was calculated. Daily nutrient intakes were obtained from the self-reported three-day dietary records for the kinds and the amounts of foods consumed by the student subjects. The students were also asked to complete three questionnaires : Mehrabian's eating-related characteristics questionnaire, Eysenck Personality Questionnaire, and the Berk Depression Inventory. The results of the study were as follows : 1) Reliability of factored homogeneous item dimensions (FHIDS) of the translated version of the eating-related characteristics questionnaire showed a similar profile compared with the original. Moreover, the loading values of Cronbach-$\alpha$ for some FHIDs, which were excluded in order to constitute primary-level factors (for example, 'predisposition to obesity' etc) with a high reliability, were much lower than Mehrabian's. Therefore the eating-related characteristics questionnaire could be effectively used for Korean students for predicting predisposition to obesity and eating disorders. 2) With regard to the relationship between anthropometric indices and eating-related characteristics, BMI measurements showed a high and a positive correlation with 'predisposition to obesity' and 'uncontrollable urges to eat', and a negative correlation with a 'predisposition to anorexia'. The heavier body weight and the more fat mass that the subjects had, the higher the probability that the subjects were overeating. 3) The intakes of some minerals (Fe, K, Na) and Vitamin C showed significantly negative correlations with a 'predisposition to obesity' and a 'predisposition to anorexia'. But the intakes of vitamin B$_2$, niacin, and retinol were positively correlated with'uncontrollable urges to eat'. 4) Among personality dimensions, neuroticism had a positive correlation with a 'predisposition to obesity', 'uncontrollable urges to eat', and 'predisposition to anorexia'. 5) Neuroticism was negatively correlated with intakes of calories, carbohydrates, K, Fe, Vitamin C, etc. On the contrary, all personality dimensions were positively correlated with intakes of retinol. In conclusion, the translated version of Mehrabian's eating-related characteristics questionnaire appears to be effective for nutritional or psychological assessments of any predisposition to eating disorders among Korean college students.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.37 no.1
• /
• pp.124-129
• /
• 2010

Seckel syndrome is an autosomal recessive disorder characterized by intrauterine growth retardation and post-natally by dwarfism, severe microcephaly, bird-headed profile with receding chin, prominent nose, joint defects, clubfoot, sparse hair, malformation of genitourinary tract and rectum, mental retardation and hematological disorders. There is also a reduction in the number of blood cells. Dental anomalies of Seckel syndrome are crowded teeth with malocclusion, enamel hypoplasia, absence of some teeth and taurodontism. This report described the oral and maxillofacial manifestations of children associated with Seckel syndrome. Children with Seckel syndrome have several dental and skeletal irregularities. The purpose of this study was to report the dental and medical characteristics of the patient and review the literatures of Seckel syndrome.

• Journal of Genetic Medicine
• /
• v.6 no.2
• /
• pp.121-130
• /
• 2009

Medical Research Center, Seoul National University College of Medicine, Seoul, Korea To analyze a wide variety of polymorphisms in patients with endometriosis is important since this disease has a strong genetic component. Until now, more than 30 Korean studies have been performed in order to elucidate the possible role of specific polymorphisms in the susceptibility to endometriosis. The most meaningful polymorphisms in Korean patients with endometriosis came from studies investigating GSTM1, AhRR, ER-alpha, VEGF, AHSG, and TNF-alpha. However, following studies should be made to confirm the consistency of the data to have some implications in the prediction of endometriosis. In this review, we also present the future direction of the association studies in complex trait disease such as endometriosis.

• Journal of Sasang Constitutional Medicine
• /
• v.11 no.1
• /
• pp.79-102
• /
• 1999

1. Purpose : This studied Cold and Heat syndromes about Four-form Constitutional Physicalogy. It is for help the comprehension, diagnosis and treatment of physicalogy and pathology about each type. 2. Method : I studied the conception of Cold and Heat sydrome in the existing Oriental Medicine before Constitutinal Medicine, through a few symptoms(constipation, diarrhea, sweat, urine, vomiting) and physicalogy, pathology in Dongyi-Soose-Bowon. 3. Results & Conclusion : In the viewpoint of Pathological Disease and a Chapter Name, Shaoyin has the Exterior-Febrile and Interior-Cold Disease, as the constitutional primary cause of the Interior-Cold Disease, Shaoyang has the Exterior-Cold and Interior-Febrile Disease, as the Interior-Febrile Disease, accoreing to the process of the promote incomings and outgoings of food stuffs of the Spleen and Kidney. By the way, Taiyin is classified into 'One who had had the Cold Disease Primarily and the Febrile', Taiyang has the nature of 'No Cold, No Heat' that is not tendency to The Cold or Heat sydromes, according to promote the respiration of air and fluid of the Liver and Lung. In the viewpoint of a few symptoms(constipation, diarrhea, sweat, urine, vomiting), we are known that cold and heat connception of the each symptome is fixed, according to nature of cold and heat in each type. These express the methood of 'constitutional demonstration'.

• Journal of Chest Surgery
• /
• v.29 no.7
• /
• pp.777-779
• /
• 1996

Recently we operated on two cases of PDA in premature infant. In both cases, indomethacin therapy had failed to close the PDA. The extremely small baby(body weight 540gm) died 28hrs postoperatively by unexpe ted intrathoracic bleeding probably due to coagulopathy related to septic condition and thrombocytopenia. The clinical course of the second case(body weight 1395gm) was complicated by ileal perforation sec- ondary to necrotizing enterocolitis. The baby underwent segmental resection of ileum with ileostomy on the 8th hospital day. On the 34th hospital day surgical closure of the PDA was done and the ile'ostomy was repaired simultaneously. Ventilator weaning was possible on the postoperative 6th day. The baby discharged on the postoperative 33th day with the body weight of 2050gm.

• Food Science and Preservation
• /
• v.30 no.2
• /
• pp.347-357
• /
• 2023

The succulent plant Aeonium sedifolium leaves contain several compounds that are of interest for their cosmetic uses on the skin. This study measured the inhibitory effects of enzyme production and antioxidant, astringent effects and skin wrinkles using Aeonium sedifolium leaves (ASL). The total phenolics compounds (TPC) content of ASL under optimal extraction conditions was 34.49 mg/g for hot water extract (ASLW) and 61.64 mg/g for 50% ethanol extract (ASLE). The ASLW and ASLE extracts were freeze-dried, powdered, and used as solids. TPC content, 2,2-diphenyl-1-picrylhydrazy (DPPH) radical scavenging activity, and 2,2'-azinobis (3-ethylben-zothiazoline 6-sulfonate) (ABTS) radical inhibition of the ASL phenolics were tested. The DPPH radical scavenging activities of ASLW and ASLE were tested at a TPC of 100 ㎍/mL. ABTS radical inhibition showed antioxidant activity of 100.00% in ASLW and ASLE, and the antioxidant protection factor of ASLW and ASLE was 1.07 and 1.22, respectively. The thiobarbituric acid-reactive substance (TBARS) inhibitory activity of ASLW and ASLE was 77.00%. The elastase inhibitory activity of ASLE was 69.03%, and collagenase inhibition activity for ASLW and ASLE was 29.82% and 54.76%, respectively. The astringent effect of ASLE was 89.82% at a TPC of 200 ㎍/mL. Thus, we concluded that ASL has the potential as a functional cosmetic ingredient with anti-aging effects on the skin.

• Korean Journal of Biological Psychiatry
• /
• v.8 no.1
• /
• pp.20-36
• /
• 2001

The debate about whether depressive disorders should be divided into categories or arrayed along a continuum has gone for decade, without resolution. In our review, there is more evidence consistent with the spectrum concept than there is with the idea that depressive disorders constitute discrete clusters marked by relatively discontinuous boundaries. First, "depression spectrum", "is there a common genetic factors in bipolar and unipolar affective disorder", "threshold model of depression" and "bipolar spectrum disorder" are reviewed. And, a new subtype of depression is so called SeCA depression that is a stressor-precipitated, cortisol-induced, serotonin-related, anxiety/aggression-driven depression. SeCA depression is discussed. But, there is with the idea that depressive disorders constitute discrete subtypes marked by relatively discontinuous boundaries. This subtypes of depressive disorder were reviewed from a variety of theoretical frames of reference. The following issues are discussed ; Dexamethasone suppression test(DST), TRH stimulation test, MHPG, Temperament Character Inventory(TCI), and heart rate variability(HRV).

• Mood & Emotion
• /
• v.10 no.1
• /
• pp.13-21
• /
• 2012

Suicide is a complex behavior associated with various neurobiological and psychosocial factors. It is considered that genetic polymorphism combined with environmental stress such as child-adolescent trauma make differences in neurobiological systems, which cause psychiatric disorders or pessimistic personality, impulse-aggressive behaviors, lack of judgment, and finally result in suicidal behavior. Much progress in the neurobiology of suicide has been made over the several decades. There seems to be a hereditary disposition to suicide independent of psychiatric disorder. The changes in neurotransmitters, neurohormones, neurotrophic factors, cytokines, lipid metabolisms related with their genetic polymorphism can contribute to disturbance of signal transductions and neuronal circuits vulnerable to suicide. It is likely that the main factors are dysfunctions of serotonin (5-HT) and hypothalamus-pituitary-adrenal (HPA) axis. Our understanding about the neurobiology of suicide is still limited. However, clinical practice could be assisted by neurobiological findings capable of making the detection of risk populations with higher sensitivity and the development of new treatment interventions. The settlement of biological markers in suicidal behaviors and their relationships is required.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1996.04a
• /
• pp.204-204
• /
• 1996

모체의 당뇨병은 신생아 호흡부전 증후군의 중요한 소인의 하나이며, 이것은 태아의 폐성숙이 지연되어 폐포를 안정화시키는 표면활성물질의 결여에 기인하는 것으로 알려져 있다. 폐의 표면활성물질은 지질과 소량의 단백으로 이루어진 복합물질로서 그 주성분은 phosphatidyl choline이며 동물의 종속에 관계없이 임신 말기에 그 양이 현저히 증가한다. 양수내 인지질은 주로 태아 폐에서 유래하므로 임신 말기의 양수내 lecithin/sphingomyelin(L/S)비 측정으로 태아의 호흡부전 증후군을 예측할 수 있다. 일반적으로 당뇨병 모체의 양수는 L/S비가 낮아 당뇨병 산모로 부터 출생한 신생아에서 호흡부전증의 발생빈도가 높으므로 이를 예방하기 위하여 부신피질호르몬의 투여가 고려되고 있다.

• Journal of Veterinary Clinics
• /
• v.12 no.1
• /
• pp.849-852
• /
• 1995

데마슘과 사상균의 일종인 Curvularia lunata가 식물파편으로 오염된 흙에 의해 눈에 외상을 입은 젊은 수토끼(Orytolaggus cunuculis)에서 각막궤양을 일으킨 것으로 밝혀졌다. 이 토끼는 직경 1.5 mm의 각막궤양, 각막부종, 전방축농, 눈물 등을 나타내었다. 각막 소파시료의 KOH 표본과 진균배지에서의 분리를 통해 진균이 확인되었다. 눈의 외상은 진균성각막염의 발생소인이었다. 토끼장의 흙은 Curvularia lunata의 집락을 많이 형성하였으며, 이것이 감염원으로 추정되었다. 이것은 애완용 토끼에서 Curvularia lunata에 의한 안진균증의 최초의 보고인 것으로 판단된다. 외상의 병력이 있는 동물임상의 다양한 상황에서 Curvularia lunata의 병인론적 역할이 연구되어야 함을 강조하였다.