• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.2
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• pp.242-248
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• 2006

배경 : 의과학과 사회-경제학의 발전은 인간 수명 연장에 지대한 공헌을 해 왔다. 그러나 결과적으로 피부 질환으로 고생하는 노인 인구도 증가하였다. 본 연구에서는 동국대학교 한방 안이비인후피부과에 피부질환을 주소증으로 내원한 성인 환자들을 대상으로 임상 양상을 조사해 보고 고령사회에서 어떻게 한방 피부과 의료 수요 변화에 대처하고 발전해 나아갈 수 있을지 그 방법을 모색해 볼 수 있는 근거 자료로 활용하기 위해 수행하였다. 연구방법 : 2002년 1월부터 2004년 12월 까지 3년 동안 동국대학교 한방 안이비인후피부과에 피부 질환을 주소증으로 내원한 319명의 환자를 대상으로 하였다. 그들을 내원시기, 연령, 성별로 나누어 질환별 분포를 조사하였다. 통계분석은 $X^2$ test(Window, SPSS 11.0)를 사용하였고 p <.05를 유의수준으로 하였다. 결과 : 2002년부터 2004년 까지 질환별 분포를 살펴보면 습진 21.9%, 소양증 20.4%. 여드름 16.9%,로 나타났다. 2002년에는 습진 17.0%, 소양증 16.0%, 여드름이 14.9%였다. 2003년에는 소양증 34.2%, 두드러기가 23,3%, 습진이 17.1%였다. 2004년에는 습진 61.4%, 여드름 21.1%, 소양증 15.8%였다. 이들 결과는 통계적으로 유의한 차이를 보였다($X^2\;=\;54.135^{***}$, p = .000, df : 20). 남자에서는 습진이 25.0%로 가장 많았고 소양증 19.5%, 두드러기 12.5%, 지루성 피부염 11.7%로 나타났다. 여자에서는 여드름이 22.0%로 가장 많았고 소양증 20.9%, 습진 19.9%였다. 이들 결과는 통계적으로 유의한 차이를 보였다($X^2\;=\;19.839^*$, p = .031, df : 10). 20대 환자에서는 여드름이 24.1%로 가장 많았고 습진과 소양증이 각각 19.5%였다. 30대 환자군에서는 습진이 30.3%였고 소양증이 19.1%였다. 40대에서는 소양증이 28.8%였고 지루성 피부염이 16.0%였다. 50대에서는 습진이 26.7%였고 60세 이상의 그룹에서는 습진이 50.0%, 바이러스 질환과 소양증이 각각 15.0%였다. 이들 결과는 통계적으로 유의한 차이를 보였다($X^2\;=\;74.995^{**}$, p = .001, df : 40). 결론 : 상대적으로 50세 이상 연령충의 대상 환자 수가 많지 않은 원인은 여리 가지 분석이 가능할 것으로 생각된다. 연령에 따라 피부질환이 다른 양상을 보임을 고려할 때 노인층의 신체적, 경제적, 사회적 특성을 이해하고 이에 따른 효과적이고 사회-경제학적 부담을 최소할 수 있는 한방 치료 영역의 확대 및 개발이 필요할 것으로 사려된다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.45-53
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• 2016

This study examined pruritus to provide the data based on burn patient pruritus. A self-report questionnaire survey was conducted among ninety five burn survivors, who were over 18 years of age with admission periods longer than two weeks. The results indicated that the average burn range was $18.95{\pm}17.10%$, severity was $48.83{\pm}23.96$, and distress was $46.42{\pm}25.80$. A significant difference in pruritus consequences was observed according to frequency. The patients consistently experienced pruritus, even if it happened less often, difficulty in falling asleep (F=4.817, p=.004), poor mood (F= 5.955, p=.015)), and loss of concentration (F=6.483, p<.000). A significant difference in the pruritus consequences according to duration was observed, lasting for 30 minutes for all groups, more than the population and less than 30 minutes, difficulty in falling asleep (F=7.452, p<.000), poor mood (F=3.655, p<.015), and loss of concentration (F=12.564, p<.000). The frequency, duration (r=.29, p=.004), severity (r=.45, p<.000), distress (r=.44, p<.000), and consequences of pruritus in burn patients (r=.29, p=.004) showed a positive correlation. The results of this study could be used as a base material for the care of burn patients experiencing pruritus.

• Journal of Sasang Constitutional Medicine
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• v.11 no.2
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• pp.361-376
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• 1999

1. Backgrounds and Purpose : Pruritus, one of the most common dermatological symptoms, was clinically examined with a view to a better understanding of its characteristics for more accurate treatment. 2. Method : For 22 months from November in 1997 to September in 1999 we selected outpatients who had consulted for itchiness more than twice in the department of Sasang Constitution of the Pundang Oriental medical hospital, Dongkook University, and 59 of those (35 males and 24 females) were confirmed of their course of treatment. From their medical records and history, we learned the general characteristics and patterns of pruritus, and the qualities and effects of its various treatments. 3. Result and Conclusion : Pruritus was more complained by men than by women and the largest age groups were 20's and 30's. For its suffering period, the duration of 1 month to less than 1 year was the greatest, and most patients had already experienced western medical care. Itchiness affected them almost day and night. In addition, many patients had abnormal bowel habits as a general symptom. According to Sasang Constitution, the Soeumin gave sleep disturbance and indigestion; the Soyangin showed a different pattern in their tongue coatings and bowel habits; the Taeumin had different tongue coatings and sweating pattern. The commonly prescribed herbal formula for pruritus was Gakhangjungisan, Yangkyuksanhwatang, Chungsimyonjatang. As for their efficiency, 61.0 % of patients improved, whereas 39.0 percent did not. Patients aged over 30 showed a more significant improvement than those of 20 years or under, and the duration of less than 1 year was more significantly improved than that of 1 year or more. Those who had no experience in western medical care or had been continuously treated showed a more significant improvement than those with intermittent treatments, and severe pruritus was more significantly improved than mild pruritus.

• Journal of Veterinary Clinics
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• v.28 no.3
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• pp.273-279
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• 2011

Botulinum toxin type A (BoNT/A) has been proven to be a safe and effective treatment for wrinkles in human. As well as the anti-wrinkle effects, the anti-pruritic effect of BoNT/A has been revealed from several researches for new therapy. The aim of this study was to investigate the anti-pruritic effect of BoNT/A against histamine-induced pruritus on canine skin. Five clinically healthy beagles were included in the study. All dogs were received 0.05 ml (5 Unit) of BoNT/A on the right dorsal thoracic region as an experiment and the same volume of saline solution was injected on the left dorsal thoracic region as a control, respectively. Intradermal histamine injections were performed four times (before treatment and days 1, 3 and 7 after BoNT/A injection). The severity of pruritus, the diameter and thickness of wheal, the erythema index and cutaneous temperature were assessed. The severity of pruritus was reduced on BoNT/A treated sides, compared with saline treated sides (p < 0.05). BoNT/A decreased wheal size, in both diameter and thickness (p < 0.05). Although, erythema index of both sides were increased after first histamine injection, BoNT/A treated sides showed the low-value as compared with saline treated sides. Cutaneous temperature was decreased significantly on BoNT/A treated sides. These results indicates that BoNT/A reduce histamine-induced pruritus on canine skin and suggested a possibility of application of BoNT/A for local intractable dermatologic problem in dogs.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.9
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• pp.4412-4420
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• 2013

Alcohol affects human body very seriously by causing different types of disease. Therefore, a great deal of studies on alcohol addiction have been conducted. There is little, however, on skin problem in relation to alcohol abuse in domestic researches. This study, with this reason, has been conducted on alco holic women, especially who have sensitive skin, with pruritus. From May 1st until 20th, 2013, surveys using same questionnaires had been carried out for the two different groups. one with 114 female alcoholics from four different clinics for acoholics through the nation, the other with 106 residents without alcoholic problems in Cheong-ju and Seong-nam city. From the comparative study of those surveys, alcohol addicts showed higher scores on pruritus than those without alcoholic problems. In addition, Audit-K score had positive correlation with pruritus score, and drinking cycle and quantity, too, had been found related to pruritus. It is expected that the findings will be used as a fundamental data for treating alcohol addicts with skin disease and leading more active researches on this field for the future.

• The Monthly Diabetes
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• s.197
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• pp.52-53
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• 2006

• 대한한약
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• s.2
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• pp.325-326
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• 1998

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.4
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• pp.41-50
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• 2015

Objectives : 선태는 아토피 피부염에서 소양증 완화를 위해 사용되고 있다. 본 연구에서는 면역계 및 신경계 손상을 일으킨 rat model에서 선태 추출물이 소양증 완화에 효과가 있는지 알아보고자 한다.Methods : 출생 48시간 이내의 rat을 대상으로, capsaicin(50 mg/kg)을 피하 투여하였다. 임의로 선정된 12마리의 실험군에 3주 동안 선태 추출물(0.5g/kg)을 매일 경구 투여하였다. 이후 scratching behavior 와 dermatitis score를 측정하였다.Results : 선태 투여군과 대조군에서 scratching number 와 dermatitis score의 차이가 없었다.Conclusions : 위의 결과로부터 capsaicin으로 유발한 아토피 피부염 rat model에서 선태의 소양증 완화 효과가 없다는 것을 알 수 있었다. 아토피 피부염의 효과적인 치료를 위해 면역계 뿐만 아니라 신경계 손상 회복시키는 약물을 찾기 위한 더 많은 연구가 필요할 것으로 생각된다.

• 월간산업보건
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• s.231
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• pp.4-14
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• 2007

• Journal of Korean Medical classics
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• v.19 no.1 s.32
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• pp.194-201
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• 2006

일반래설(一般來說), 상한소양병포괄소시호탕증(傷寒小陽病包括小柴胡湯證), 시호계지탕증(柴胡桂枝湯證), 대시호탕증(大柴胡湯證), 황금탕증(黃芩湯證), 시호계지건강탕증(柴胡桂枝乾薑湯證), 시호가용골모려탕증(柴胡加龍骨牡蠣湯證). 가시한국대표성적임상의서(可是韓國代表性的臨床醫書)${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$, 주요재잡병편중(主要在雜病篇中)${\ulcorner}$한(寒)${\lrcorner}$문적소양형증용약리참천술료소양병(門的少陽形證用藥裏參闡術了少陽病) 종차가이간출(從此可以看出)${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$대소양병적인식정도여(對少陽病的認識程度與一般的傷寒體系具有明顯的區別). 필자통과분석(筆者通過分析)${\ulcorner}$동의보감(東醫寶鑑) 잡병편(雜病篇) 한(寒)${\lrcorner}$당중적유관소양형증용약적조문(當中的有關少陽形證用藥的條文), 득출여하결론(得出如下結論): ${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$당중(當中), 소양병시이구고(少陽病是以口苦), 인건(咽乾), 목현(目眩), 협만(脇滿), 건구(乾區), 왕래한열등증상위주(往來寒熱等症狀爲主), 발병부위시소양병호발부위태양양명지간화흉협(發病部位是少陽病好發部位太陽陽明之間和胸脇); 기재적주요치방시소시호탕(記載的主要治方是小柴胡湯), 황금탕(黃芩湯), 십조탕등삼개처방(十棗湯等三個處方). 종저일점가이간출(從這一點可以看出)${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$불구니어(不拘泥於)${\ulcorner}$상한론(傷寒論)${\lrcorner}$적체계(的體系), 갱가중시실용성(更加重視實用性), 즉이증상위중심료해병정(卽以症狀爲中心了解病情), 심조갱가적합적치법여치방(尋更加適合的治法與治方). 기대금후능유인연구유관십조탕시부가이열입소양병치방화(期待今後能有人硏究有關十棗湯是否可以列入少陽病治方和)${\ulcorner}$동의보감(東醫寶鑑)${\lrcorner}$육경형증용약당중적표본개념(六經形證用藥當中的標本槪念).