• Title/Summary/Keyword: 소규모 경시적 마이크로어레이

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Statistical Analysis of a Small Scale Time-Course Microarray Experiment (소규모 경시적 마이크로어레이 실험의 통계적 분석)

  • Lee, Keun-Young;Yang, Sang-Hwa;Kim, Byung-Soo
    • The Korean Journal of Applied Statistics
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    • v.21 no.1
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    • pp.65-80
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    • 2008
  • Small scale time-course microarray experiments are those which have a small number of time points. They comprise about 80 percent of all time-course microarray experiments conducted up to 2005. Several statistical methods for the small scale time-course microarray experiments have been proposed. In this paper we applied three methods, namely, QR method, maSigPro method and STEM, to a real time-course microarray experiment which had six time points. We compared the performance of these three methods based on a simulation study and concluded that STEM outperformed, in general, in terms of power when the FDR was set to be 5%.