• Journal of Korea Entertainment Industry Association
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• v.13 no.7
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• pp.521-529
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• 2019

The purpose of this study was to examine the effects of customized cognitive stimulation therapy on cognition, depression, and activities of daily living in elderly with dementia in the community. The program consisted of 7 sessions, 50 minutes once a week, from March 4 to April 26, 2019. As a result, customized cognitive stimulation therapy improved the overall cognitive function, and it also increased the level of independence in the daily living and reduced the depression of the experimental group. It also showed significant differences in cognitive function when compared with control group. Therefore, the customized cognitive stimulation therapy of this study was to grasp the cognitive function of the elderly with dementia and present the cognitive tasks to the subjects for selection that induced interest and proved to be effective. Afterward, the activities were organized by difficulty according to the level of cognitive function for each session, leading to the improvement of cognitive function. Additionally, the subjects were experienced success by participating actively and continually in the activities selected with interest. Through this, it was thought to have a positive effect on the spontaneity of activities of daily living and decrease depression.

• Korean Journal of Biological Psychiatry
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• v.6 no.2
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• pp.153-160
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• 1999

Animal models can provide a useful tool for the study of some aspects of psychiatric disorders and their treatment. The four criteria for the evaluation of animal models of psychiatric disorders are as following : 1) similarity of inducing conditions 2) similarity of behavioral state 3) common underlying neurobiological mechanisms 4) reversal by clinically effective treatment techniques. Several animal models have been proposed for schizophrenia : phenylethylamine model, L-dopa model, hallucinogen model, cocaine model, amphetamine model, phencyclidine model, noradrenergic reward system lesion model, reticular stimulation model, social isolation model, conditioned avoidance reaction, catalepsy test, paw test, self-stimulation paradigms, latent inhibition paradigms, blocking paradigms, prepulse inhibition of the startle reflex, rodent interaction, social behavior in monkeys, hippocampal damage, high ambient pressure, and models using selective breeding. Among them, animals with bilateral lesion of the hippocampus may provide an adequate animal model for several symptoms of schizophrenia, and ketamine model can reproduce negative symptoms and cognitive deficits as well as positive symptoms of schizophrenia. In conclusion, no model of schizophrenia is entirely representative of the disease, and findings gleaned from model systems must be cautiously interpreted. Furthermore, the process of developing and validating animal models must work in concert with the process to identify reliable measures of human phenomenology.