• Proceedings of the Korean Society for Information Management Conference
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• 2012.08a
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• pp.143-146
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• 2012

본 연구에서는 MEDLINE에 수록된 논문의 암 관련 우울증 문헌을 대상으로 MeSH(Medical Subject Headings) 키워드를 이용하여 1992년부터 2011년까지 20년간의 연구 동향을 분석하였다. 암과 우울증에 해당하는 MeSH 키워드를 주제로 다룬 논문 3,389편과 50,778개의 키워드를 대상으로 주요 학술지 및 암 발병 위치와 우울증 치료요법을 분석하였다. 암 관련 우울증 논문의 암 발병 위치별 빈도는 유방암이 799편으로 가장 높았으며, 폐암, 전립선암, 뇌종양, 두경부암이 뒤를 이었다. 또한 우울증 치료 요법별 빈도는 비약물치료가 552편으로 약물치료 400편보다 높게 나타났으며 비약물치료는 크게 상담치료와 상담 외 치료에 대한 키워드로 구분되었고, 약물치료는 치료 요법명과 약명으로 다시 구분되었다.

• Journal of Biomedical Engineering Research
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• v.38 no.5
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• pp.271-276
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• 2017

Cancer biomarkers are using in the diagnosis, staging, prognosis and prediction of disease progression. But, there are not sufficiently profiled and validated in early detection and risk classification of prostate cancer. In this study, we have devoted to finding a panel of serum biomarkers that are able to detect the diagnosis of prostate cancer. The serum samples were consisted of 111 prostate cancer and 343 control samples and examined. Eleven biomarkers were constructed in this study, and then nine biomarkers were relevant to candidate biomarkers by using t test. Finally, four biomarkers, PSA, ApoA2, CYFRA21.1 and TTR, were selected as the prostate cancer biomarker panel, logistic regression was used to identify algorithms for diagnostic biomarker combinations(AUC = 0.9697). A panel of combination biomarkers is less invasive and could supplement clinical diagnostic accuracy.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.sup1
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• pp.116-120
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• 2008

Prostate cancer is the second leading cause of cancer death of men in western countries and the death related to this disease in Korea is also getting increased. Although anatomic imaging tools such as transrectal US or MRI have been playing a great role in detection of primary prostate lesion, the evaluation of regional lymph node or distant organ metastasis using these modalities is not successful. $^{18}F-FDG-PET$ scan is emerging diagnostic tool for various malignancies. Considering the usual characteristics of prostate cancer such as slow growing and osteoblastic metastasis, the application of FDG PET scan to this disease might be limited. However, in advanced prostate cancer refractory to chemotherapy, FDG PET scan show strong FDG uptake and SUV changes in serial PET scan can be a good indicator of treatment response. Although FDG PET can be useful only in limited cases of prostate cancer, its indication can be widened in future owing to rapid technical improvement and accumulated experiences in this field.

• The Korean Journal of Nuclear Medicine
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• v.36 no.2
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• pp.140-142
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• 2002

A 67-year-old woman who had undergone anterior resection for a moderately differentiated adenocarcinoma of the rectum and wedge resection for liver metastasis presented with hematogenous lung metastasis. Metastatic pulmonary nodules in both lung fields were shown on plain chest radiograph and CT. Ga-67 SPECT images revealed accumulation of radioactivity corresponding to the pulmonary nodules. The authors present an unusual case of accumulation of Ga-67 in metastatic pulmonary nodules in a patient with a moderately differentiated adenocarcinoma of the rectum.

• Journal of Veterinary Clinics
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• v.19 no.2
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• pp.256-259
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• 2002

A 39 kg, 7-year-old male Labrador Retriever dog with a 3-month history of epistaxis, sneezing, and nasal discharge was referred to the Veterinary Medical Center of the Tokyo University. On the plain X-ray and computed tomography (CT) of the head showed increased density of the soft tissue in the left nasal cavity and the tumor infiltrated to nasal septum. The tumor mass removed by rhinotomy. Histopathological examination of the mass revealed adenocarcinoma. Four weeks after the surgery, the radiation therapy was performed twice a week for f weeks. 4 months after surgery, the dog had a recurrence in nasal cavity and administered carboplatin 300 mg/$m^2$ twice. However, the tumor had no response to chemotherapy, additional surgery and additional radiation therapy, and the dog was euthanized at the owner's request. At necropsy, metastatic proliferation was confirmed in the lung, lymph nodes and nasal cavity.

• Journal of Chest Surgery
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• v.28 no.12
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• pp.1144-1149
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• 1995

Adenocarcinoma involving esophago-gastric junction[EGJ is usually originated from the gastric cardia and it presents unique clinical manifestations, requires special surgical care, and bears a much poor prognosis. We analyse the clinical data of 109 adenocarcinoma involving EGJ operated between August, 1987 and March, 1994. Curative resection of primary tumor including esophagus and lymph node dissection was possible on 102 cases[93.5% . Among these cases, 89 cases were advanced state over the stage III. The operative mortality was 1.8% and postoperative morbidity was 16.5%. The overall 3 year and 5 year survival rate was 48.5%, 34.1% each, and median survival was 27.5 month in the curative resected cases. The treatment failure was mainly distant metastsis including lymph node, except one local recurrence.Among many factors influencing long term results of resected adenocarcinoma involving EGJ, the only effort a surgeon can make is to attain completeness of tumor removal by dissecting all involved lymph node and ensuring adequate tumor free margins of both esophageal and cardiac side.

• Journal of Chest Surgery
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• v.30 no.4
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• pp.457-461
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• 1997

L casts of Barrett's esophagus complicated with stricture is reported. A 82 years old male was undergone distal esophagectomy '||'&'||' esophagogastrostomy on suspicion of malignancy. The microscopic examination of specimen taken from the lesion revealed the "tall columnar cells" which were indicative of Barrett's esophagus, hence the diagnosis. Barrett's esophagus is a rare disease in Korea. Because of the malignant potential of the disease, surgery involving esophagectomy is often required.d.

• Journal of Chest Surgery
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• v.37 no.1
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• pp.92-94
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• 2004

Mucoepidermoid carcinoma of the lung is extremely rare. This rare tumor arise beyond the carina, usually main stem bronchi, but occasionally in lobar or segmental airways, This tumor presents with symptoms of bronchial irritation or obstruction. Distant metastasis is an uncommon, therefore complete surgical resection is the treatment of the choice. The prognosis of this tumor correlates with the histologic grade of the tumor. We experienced a case of mucoepidermoid carcinoma arising from the right middle lobe, which was treated with the right middle lobectomy, with good result. We report this case and follow-up of the patient.

• Journal of Chest Surgery
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• v.13 no.1
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• pp.66-71
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• 1980

This is one case report of coexisting two histologically different carcinomas in the different lobes of the right lung, which operated the right pneumonectomy in the Dept. of Thoracic and Cardiovascular Surgery Hanyang University Hospital. The 43 years old male patient complained coughing, blood tinged sputum and weight loss. The chest films [PA and lateral view] showed a small round hazy shadow in the posterior segment of the right upper lobe and irregular hazy densities in the right middle lobe and hilar area. Histopathologically, the tumor in the posterior segment of the right upper lobe was consisted of a tissue of adenocarcinoma and the tumor in the right middle lobe was consisted of a tissue of well-differentiated bronchial squamous cell carcinoma.

• The Monthly Diabetes
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• s.203
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• pp.22-43
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• 2006

지난 18일 통계청이 발표한 2005년 사망원인통계결과에 의하면 2005년에 각종 암으로 사망한 사람은 총65만명으로 사망원인 중 1위를 차지했다.(전체 사망자의 26.7%), 그 다음으로는 뇌혈관 질환,심장질환,자살,당뇨병 순으로 통계 됐다. 2005년에 가장 많이 사망한 암은 폐암으로 전체 사망자의 28.4%인 13,805명이였으며, 다음으로는 위암(22.6%), 간암(22.5%), 데장암(12.5%), 췌장암(7%)의 순으로 나타났다. 사망률이 가장 많이 증가한 암은 2004년과 같이 폐암이며, 그 다음으로는 대장암,췌장암,전립선암이다. 반면 사망률이 가장 많이 감소한 암은 위암이고, 그 다음이 자궁암이다. 이렇듯 암은 한국인에게서 가장 많이 발견되는 질병 중에 하나이며, 이로 인해 많은 사람들이 사망하고 있다. 10월호에서는 과연 암이란 어떤 질병이고, 어떻게 우리의 생명을 위협하는지 알아보고자 한다.