• The Journal of Korean Society for Radiation Therapy
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• v.15 no.1
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• pp.53-60
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• 2003

I. Purpose It is essential to have the correct body contour information for the calculation of dose distribution. The role of CT images in the radiation oncology field has been increased. But there still exists a method to use cast or lead wire for the body contour drawing. This traditional method has drawbacks such as in accurate and time consuming procedure. This study has been designed to overcome this problem. II. Materials and Methods A digital camera is attached to a pole which stands on the opposite side of the gantry. Positional information was acquired from an image of the phantom which is specially designed for this study and located on the isocenter level of the simulator Laser line on the patients skin or on the phantom surface was digitized and reconstructed as the contour. Verification of usefulness this technique has been done with various shape of phantoms and a patients chest III. Results and Conclusions Contours from the traditional method with the cast or lead wire and the digital image method showed good agreement within experimetal error range. This technique showed more efficiente in time and convenience. For irregular shaped contour, like H&N region, special care are needed. The results suggest that more study is needed. To use of the another photogrammatory techinique with two camera system may be better for the actual clinical application

• Journal of the Korean Society of Radiology
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• v.10 no.8
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• pp.565-569
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• 2016

Recently, a use of linear accelerator with a multi-leaf collimator(MLC) for radiation therapy is increasing. The importance of quality assurance (QA) for the linear accelerator is emphasized as the side effects of the inaccurate delivery of the radiation beam has been increased according to the high dose irradiation technique. In this study, The $HgI_2$ and $PbI_2$ photoconductor layer samples of $400{\mu}m$ thickness were fabricated using sedimentation method among particle-in-binder technology. From the fabricated samples, the electrical properties(dark current, output current, response properties and linearity) were investigated. From the experimental results, $HgI_2$ has good charge signal generation and linearity. Finally, from the signal response results about various thickness of $HgI_2$ sensor, the signal creation efficiency of $400{\mu}m$ thickness of $HgI_2$ sensor has the highest value and the excellent reproducibility below ${\pm}2.5%$.

• Journal of radiological science and technology
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• v.39 no.4
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• pp.543-547
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• 2016

Acute stroke is a one of common disease that require fast diagnosis and treatment to save patients life. however, the acute stroke may cause lifelong disability due to brain damage with no prompt surgical procedure. In order to diagnose the Stroke, brain perfusion CT examination and possible rapid implementation of 3D angiography has been widely used. However, a low-dose technique should be applied for the examination since a lot of radiation exposure to the patient may cause secondary damage for the patients. Therefore, the degradation of the measured CT images may interferes with a clinical check in that blood vessel shapes on the CT image are significantly affected by gaussian noise. In this study, we employed the spatio-temporal technique to analyze dynamic (brain perfusion) CT data to improve an image quality for successful clinical diagnosis. As a results, proposed technique could remove gaussian noise successfully, demonstrated a possibility of new image segmentation technique for CT angiography. Qualitative evaluation was conducted by skilled radiological technologists, indicated significant quality improvement of dynamic CT images. the proposed technique will be useful tools as a clinical application for brain perfusion CT examination.

• Journal of radiological science and technology
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• v.33 no.1
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• pp.51-59
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• 2010

We developed an analysis software that automatically detects incoming isotopes for multi-purpose gamma-ray detectors. The software is divided into three major parts; Network Interface Module (NIM), Spectrum Analysis Module (SAM), and Graphic User Interface Module (GUIM). The main part is SAM that extracts peak information of energy spectrum from the collected data through network and identifies the isotopes by comparing the peaks with pre-calibrated libraries. The proposed peak detection algorithm was utilized to construct libraries of standard isotopes with two peaks and to identify the unknown isotope with the constructed libraries. We tested the software by using GammaPro1410 detector developed by NuCare Medical Systems. The results showed that NIM performed 200K counts per seconds and the most isotopes tested were correctly recognized within 1% error range when only a single unknown isotope was used for detection test. The software is expected to be used for radiation monitoring in various applications such as hospitals, power plants, and research facilities etc.

• Korean Journal of Food Science and Technology
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• v.32 no.3
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• pp.525-530
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• 2000

A study was carried out to establish the detection method of irradiated agricultural products cultivated in Korea by Thermoluminscece(TL). Samples were irradiated using Co-60 gamma rays at various doses(0.05, 0.1, 0.2, 0.3 and 0.5 kGy). After irradiation, separated minerals of the samples measured by TL. TL intensity increased with increasing doses and the irradiated samples were higher than the non-irradiated samples. TL first and second glow curves showed maximum TL temperature point at $176.16{\sim}190.08^{\circ}C$ and $143.84{\sim}146.56^{\circ}C$, respectively. All the irradiated samples can be classified correctly by the shape of the glow curve and the glow curve ratio. Correlation coefficients of ginger, carrot, potato and sweet potato were 0.9968, 0.8522, 0.9612 and 0.9071, respectively, that showed very high correlation between irradiation dose and TL intensity. Therefore, these results suggest that TL measurement is an useful detection method for irradiated agricultural products.

• The Journal of the Acoustical Society of Korea
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• v.36 no.3
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• pp.172-178
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• 2017

Ultrasound has been widely used for biological and medical applications including induction of cell death, but a precise mechanism of induced cell death by ultrasound is controversial. In this study, an irradiation system with 40 kHz ultrasound was developed for a suitable cell death test of a representative unicellular organism, yeast, and used to study the biological effect of ultrasound on inducing cell death. Potassium Iodide (KI) dosimetry was used to devise an optimal system that successfully delivers 40 kHz ultrasound and produces reactive oxygen species in a 1.5 ml Eppendorf tube. Cell death was observed in an ultrasound transmission time-dependent fashion in this system. Thermal effect during irradiation was not observable in ultrasound induced cell death. Co-treatment of 40 kHz ultrasound and hydrogen peroxide showed a synergistic effect in inducing cell death. This finding suggests that 40 kHz ultrasound is related to reactive oxygen species formation. However, NAC (N-acetyl-L-cysteine) oxygen scavenger slightly inhibited the cell death by 40 kHz ultrasound. It was also found that 40 kHz ultrasound induced cell death was slightly inhibited by inhibitors of necrosis or apoptosis (glycyrrhizin or zVAD-fmk). This study suggests that cell death induced by 40 kHz ultrasound may not be exclusively related to reactive oxygen species formation and thermal effects in irradiated yeast cells.

• Progress in Medical Physics
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• v.15 no.4
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• pp.179-185
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• 2004

To deal with tumor motion from respiration is one of the important issues for the advanced treatment techniques, such as the intensity modulated radiation therapy (IMRT), the image guided radiation therapy (IGRT), the three dimensional conformal therapy (3D-CRT) and the Cyber Knife. Studies including the active breath control (ABC) and the gated radiation therapy have been reported. Authors have developed the device for reducing the respiration effects and the diaphragm motions with this device were observed to determined the effectiveness of the device. The device consists of four belts to immobilize diaphragm motion and the vacuum cushion. Diaphragm motions without and with device were monitored fluoroscopically. Diaphragm motion ranges were found to be 1.14 ～ 3.14 cm (average 2.14 cm) without the device and 0.72～1.95 cm (average 1.16 cm) with the device. The motion ranges were decreased 20 ～ 68.4% (average 44.9%.) However, the respiration cycle was increased from 4.4 seconds to 3.7 seconds. The CTV-PTV margin could be decreased significantly with the device developed in this study, which may be applied to the treatments of the tumor sited diaphragm region.

• Progress in Medical Physics
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• v.7 no.1
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• pp.53-64
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• 1996

Purpose: The purposes of this paper are to develop a theoretical basis that the beam directions should be considered when the mechanical accuracy of teletherapy machine is evaluated by the star pattern test, to develop methods using asymmetric field in length to simulate beam direction for the case that beam direction does not appear on film. Method: In evaluating mechanical rotational accuracy of the gantry of teletherapy unit by the star pattern test, the direction of radiation beams was considered. A star pattern using some narrow beams was made. Density profiles at 10cm far from estimated gantry axis on the star pattern were measured using an optical densitometer. On each profile, one coordimate of a beam axis was determined. A pair of coordinates on a beam axis form an equation of the axis. Assume that a unit vector equation omitted is with same direction as radiation beam and a vector equation omitted is a vector directing to the beam axis from the estimated gantry axis. Then, a vector product equation omitted ${\times}$ equation omitted is an area vector of which the absolute value is equal to the distance from the estimated gantry axis to the beam axis. The coordinate of gantry axis was obtained by using least-square method for the area vectors relative to the average of whole area vectors. For the axis, the maximum of absolute value of area vectors would be an accuracy of the gantry rotation axis. For the evaluation of mechanical accuracies of collimator and couch axes for which beam direction could not be depicted on a star pattern test film, narrow beams asymmetric in field length was used to simulate beam direction. Result: For a star test pattern to evaluate the mechanical accuracy of rotational axes of a telectherapy machine, the result considering beam direction was different from that ignoring beam direction. For the evaluation of mechanical accuracies of collimator and couch axes by means of a star pattern test, narrow asymmetric beams could simulate beam direction. Conclusion: When a star pattern test is used to evaluate the mechanical accuracy of a teletherapy unit, beam direction must be considered or simulated, and quantitatively evaluated.

• 대한방사선치료학회:학술대회논문집
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• 2005.06a
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• pp.19-22
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• 2005

Introduction: Daily Q.A is the important step which must be preceded in a radiation treatment. Specially, radiation output measurement and laser alignment, SSD indicator related to a patient set-up recurrence must be confirmed for a reasonable radiation treatment. Daily Q.A proceeds correctness and a prompt way, and needs an objective measurement basis. Manufacture of the device which can facilitate confirmation of output measurement and appliances check at one time was requested. Methods and Materials: Produced the phantom formal daily check device which can confirm a lot of appliances check (output measurement and laser alignment, field size, SSD indicator) with one time of set up at a time, and measurement observed a linear accelerator (4 machine) for four months and evaluated efficiency. Result: We were able to confirm an laser alignment, field size, SSD indicator check at the same time, and out put measurement was possible with the same set up, so daily Q.A time was reduced, and were able to confirm an objective basis about each item measurement. As a result of having measured for four months, output measurement within ${\pm}\;2\%$, and measured laser alignment, field size, SSD indicator in range within ${\pm}\;1mm$. Conclusion: We can enforce output measurement and appliances check conveniently and time was reduced and was able to raise efficiency of business. We were able to bring n cost reduction by substitution expensive commercialized equipment. Further It is necessary to makes a product as strong and slight materials, and improve convenience of use.

• Radiation Oncology Journal
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• v.4 no.2
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• pp.99-105
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• 1986

Optimal balance between control probability and risk of complication is emphasized even in present time, Although certain incidence of intestinal injury is accepted as an inevitable consequence after abdominopelvic irradiation, these complications still remain as problems. 60 mice were irradiated with 250 kVp orthovoltage x-ray machine and $200rad{\times}5/wk$ regimen. Histpathologic findings of colorectum and the relationship with occult blood test were analyzed and possible tolerable dose which would be safe from permanent complication was also estimated. Followings are the results: Mild mucosal and submucosal edema were observed in 1,000 rad irradiated group. Congestion of small vessels was prominent in 2,000 rad irradiated group and infiltration of inflammatory cells was observed in 3,000 rad irradiated group. Denuded mucosa was observed in 3,000 rad irradiated group. Occult blood test is not a proper indicator for rectal denuding or rectal ulcer, but our results suggest the possibility of using this as a relative scale of intestinal damage. Mitotic figures of crypt cells were observed even in 5,000 rad irradiated group, these suggest that the repair capacity of crypt cells are still functioning.