• Proceedings of the Korean Statistical Society Conference
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• 2004.11a
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• pp.111-116
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• 2004

스트레스 수준이 논을 것으로 예상되는 공군사관학교 수험생의 신체검사 결과로부터 신체건강 지표인 혈액 내 생화학적 요인들과 정신건강 지표인 다면 인성검사 점수를 추출하여 통계적 상관성 및 유의성을 비교 분석하였다 사관생도들 중 $10\%$의 표본을 추출하여 사관생도와 수험생 집단간의 특성 비교를 위한 비교집단으로 이용하였다. 수험생과 사관생도 집단 간의 특성 요인 비교는 Mann-whitney U 검정과 Kruskal-Wallis 검정을 이용하였다. 수험생 집단 내에서 혈중 요인 및 정신건강 지표인 MMPI 점수는 정상범주에 있었고 두 요인 간 상관성은 발견할 수 없었다. 그러나 사관생도와 수험생 집단 간의 특성 요인들에 대한 유의성 검정 결과, 특히 2학년생도들의 혈액 내 혈구 수 및 활동성 또는 적극성과 관련된 MMPI 하위척도에서 수험생 집단과 매운 유의한 차이를 보이는 특이한 현상을 발견할 수 있었고 이에 대한 해석을 언급하였다.

• Proceedings of the Korean Nutrition Society Conference
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• 2003.10a
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• pp.191-191
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• 2003

• Environmental Analysis Health and Toxicology
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• v.20 no.1
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• pp.1-11
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• 2005

환경오염의 조기 경보 시스템으로 생체지표를 이용한 생태독성 모니터링이 최근 널리 연구되고 있다. 환경내의 생물종에서 측정한 생체지표를 이용한 환경 모니터링은 생태계 수준의 영향에 대한 예측 정보를 제공해 줄 수도 있다. 이를 위해서는 생체지표와 개체군 수준에서의 반응과의 인과관계가 밝혀져야 한다. 오염물질에 대한 생체의 반응은 분자, 세포, 생화학, 생리적, 개체, 개체군, 군집 수준에서 나타나게 되며, 이러한 각 단계별 반응은 반응 시간의 규모와 독성학적, 생태적 관련성에 따라 구분 지어 볼 수 있다. 각 개별 수준에서의 반응을 종합하면 오염물질에 노출된 생체의 전제적인 영향을 이해할 수 있으며, 이러한 이해를 바탕으로 개체군에서 나타나는 영향에 대한 인과관계를 추론할 수 있다. 생체지표와 개체군 수준의 반응과의 인과관계 정립은 효율적인 환경오염 예방기능 수행에 필수적인 과정이며, 다단계 생체 지표는 각 단계별 반응의 인과관계를 밝히기 위해 가장 적절한 접근 방법이다. 수서 무척추 생물인 Chironomus의 유충은 이러한 다단계 바이오마커 연구에 매우 적절한 생물학적 모델이다. 이 논문의 첫 번째 부분은 생체지표를 이용한 환경 모니터링을, 두 번째 부분은 Chironomus의 유충에서 생체지표의 적용에 대해서 다룬다.

• Journal of Korean Society of Forest Science
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• v.112 no.1
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• pp.93-104
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• 2023

Life expectancy is increasing due to the aging of the population, which is in turn exacerbating problems such as the prevalence of various geriatric diseases. This study was established to provide basic data for the expansion of forest healing activities for the elderly by systematically analyzing the literature on how such activities affect this age group. For the collection of studies, the Korean databases RISS, KISS, Korea Med, and Science On were used, while PubMed, Cochrane Central, MDPI, and Google Scholar were used to identify reports published elsewhere. To assess the quality of the methodology used in the collected studies, the risk of bias was analyzed using Cochrane's RoB2 and RoBANS. Among 1,856 reports initially identified, 21 were finally selected for analysis in this study, which were limited to research papers on forest healing activities for the elderly published between 2000 and January 2022. In this review, the subjects were those aged 60 or older, with a total of 750 participants, ranging from at least 7 to a maximum of 88 per study. The analysis showed that the most frequently performed tests in each category were on depression as a psychological indicator in 7 studies, MMSE(Mini Mental State Examination) as a cognitive indicator in 2 studies, on blood pressure as a physiological indicator in 4 studies, on melatonin as a biochemical indicator in 2 studies, and on body fat and muscle strength as physical indicators in 3 studies. Of the 21 studies, 19 used two or more test items, with psychological indicators being most commonly measured. For the future application of forest healing activities for the elderly, various forest healing programs to prevent cognitive function decline should be developed and distributed, and follow-up studies should be continuously presented to provide the basis for forest healing activities.

• Food Science of Animal Resources
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• v.28 no.1
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• pp.91-98
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• 2008

This study was conducted to reveal the effects of pork consumption on the renal and hematochemical indices of workers occupationally exposed to an unclean environment for 6 weeks. Forty-five free-living volunteers were recruited from the workers employed in a car-engine part factory and a leather dyeing company in the Gyeonggi area. Volunteers were to submit a subject consent form prior to the study. They were asked to complete a questionnaire on dietary habits, and blood and urine samples were collected before and after the pork consumption trial. Pork dishes were fed twice weekly (150g per meal) as part of lunch or dinner at the work place. Urine N-Acetyl-${\beta}$-D-glucosamidase (NAG) levels were reduced after the trial, but total-cholesterol, HDL-and LDL-cholesterol levels did not change. However, triglyceride levels did increase significantly (p<0.005). The Zn, Pb, and Cd concentrations in serum tended to decrease, though without statistical significance. In conclusion, the regular consumption of pork may be beneficial for renal functions, however further research in this area is needed.

• Journal of Digital Convergence
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• v.11 no.1
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• pp.299-308
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• 2013

We investigated the effect of mulberry leaf extract (MLE) on blood biochemical parameters of white rats induced TCDD toxicity. Data were analyzed by One-way ANOVA and Post-Hoc Test. The numbers of leukocyte and platelet decreased by TCDD were increased dramatically after treated MLE (p<0.01). The concentration of calcium and magnesium decreased by TT were increased by MLE and shown a statistical significance (p<0.01) but the concentration of phosphorus increased by TT was decreased by MLE. In the test of parameters related to renal function, only the concentration of uric acid in the MLE group was decreased than it in TT group and shown a statistical significance (p<0.01). Also the concentration of blood glucose and the activity of amylase and lipase increased by TT were decreased after treated MLE and shown a statistical significance (p<0.01), and MLE had an control effect for elevating blood glucose. In the test of parameters related to liver function, the acticity of AST, ALT and ALP increased by TT was decreased after treated MLE and shown a statistical significance (p<0.01), and MLE had an improving effect for liver function. In the case of total cholesterol (T,cho), triglyceride( TG), LDL-cholesterol (LDL-C) and HDL-cholesterol (HDL-C) related to lipid metabolism, the amount of T,cho, TG, LDL-C increased by TT were decreased after treated MLE and shown a statistical significance (p<0.01), and MLE had an ability of anti-hyperlipidemia. From these results, we concluded that MLE could mollified TCDD toxicity in white rats exposed to TCDD.

• Journal of Digital Convergence
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• v.18 no.12
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• pp.585-594
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• 2020

At present, aging-related degenerative muscle diseases are considered a serious problem. However, the drug effect on the treatment and prevention of sarcopenia has not been investigated. The purpose of this study was to evaluate the value of extract of Pu'er tea as a remedy to alleviate the symptoms of sarcopenia. Pu'er tea extracts showed excellent radical scavenging ability. The expression of Myh3 was promoted and myotube formation also was increased by treatment of Pu'er tea extracts. These results suggest that Pu'er tea is a natural substance that promotes myogenesis, and is valuable as a material for pharmaceutical research on the prevention and treatment of various muscle diseases, including sarcopenia. And It is necessary to confirm specific indicator substances of puer tea and further study on this.

• Journal of the Korean Institute of Gas
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• v.17 no.6
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• pp.58-66
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• 2013

Among the risks which can be faced with fire, combustion toxicity is a significant influence on the survival. Fire toxicity researches have been limited generally on the lethal aspects. In this study, HF gas which can be generated from fire, and also found in general industrial site was used for analysis. Blood analysis and biochemistry analysis performed to find internal demage of experimental animals which were used for measuring average activity stopping time from Animal test(KS F2271: Gas hazard test). In addition, Using the malondialdehyde analysis, indicators of oxidative damage, we had quantitative analysis to target lymphocyte for measuring the oxidative damage caused by toxic substances.

• Journal of Digital Convergence
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• v.11 no.10
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• pp.493-505
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• 2013

We investigated the effect of red ginseng extracts on blood biochemical parameters, bone density and bone inorganic components etc. and data were analyzed by one-way ANOVA and Post-Hoc Test. In the results of our study, the level of albumin and HDL, Ca, P, Mg, and estradiol in blood, and the content of Ca, P, ash in femur were significantly increased in red ginseng treated group than in OVX group, and the level of ALP, AST, ALT, blood glucose, total cholesterol, triglyceride, LDL, creatinine, osteocalcin, and N-terminal telopeptide were significantly decreased in red ginseng treated group than in OVX group (p < 0.01). From these results, we knew that within the normal level, red ginseng extracts improved liver and kidney function, component of glucose and lipid in blood, bone density, bone ash and inorganic components in femur, and index related with bone metabolism.

• The Korean Journal of Nuclear Medicine
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• v.33 no.4
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• pp.341-351
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• 1999

Biochemical markers of bone turnover has received increasing attention over the past few years, because of the need for sensitive and specific tool in the clinical investigation of osteoporosis. Bone markers should be unique to bone, reflect changes of bone loss, and should be correlated with radiocalcium kinetics, histomorphometry, or changes in bone mass. The markers also should be useful in monitoring treatment efficacy. Although no bone marker has been established to meet all these criteria, currently osteocalcin and pyridinium crosslinks are the most efficient markers to assess the level of bone turnover in the menopausal and senile osteoporosis. Recently, N-terminal telopeptide (NTX), C-terminal telopeptide (CTX) and bone specific alkaline phosphatase are considered as new valid markers of bone turnover. Recent data suggest that CTX and free deoxypyridinoline could predict the subsequent risk of hiP fracture of elderly women. Treatment of postmenopausal women with estrogen, calcitonin and bisphosphonates demonstrated rapid decrease of the levels of bone markers that correlated with the long-term increase of bone mass. Factors such as circadian rhythms, diet, age, sex, bone mass and renal function affect the results of biochemical markers and should be appropriately adjusted whenever possible. Each biochemical markers of bone turnover may have its own specific advantages and limitations. Recent advances in research will provide more sensitive and specific assays.