• Title/Summary/Keyword: 생물학적 정보

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An Automatic Mobile Cell Counting System for the Analysis of Biological Image (생물학적 영상 분석을 위한 자동 모바일 셀 계수 시스템)

  • Seo, Jaejoon;Chun, Junchul;Lee, Jin-Sung
    • Journal of Internet Computing and Services
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    • v.16 no.1
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    • pp.39-46
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    • 2015
  • This paper presents an automatic method to detect and count the cells from microorganism images based on mobile environments. Cell counting is an important process in the field of biological and pathological image analysis. In the past, cell counting is done manually, which is known as tedious and time consuming process. Moreover, the manual cell counting can lead inconsistent and imprecise results. Therefore, it is necessary to make an automatic method to detect and count cells from biological images to obtain accurate and consistent results. The proposed multi-step cell counting method automatically segments the cells from the image of cultivated microorganism and labels the cells by utilizing topological analysis of the segmented cells. To improve the accuracy of the cell counting, we adopt watershed algorithm in separating agglomerated cells from each other and morphological operation in enhancing the individual cell object from the image. The system is developed by considering the availability in mobile environments. Therefore, the cell images can be obtained by a mobile phone and the processed statistical data of microorganism can be delivered by mobile devices in ubiquitous smart space. From the experiments, by comparing the results between manual and the proposed automatic cell counting we can prove the efficiency of the developed system.

개조개, Saxidomus purpuratus의 자원생태학적 특성치

  • 김영혜;류동기;장대수;김종빈;김성태;김영승
    • Proceedings of the Korean Society of Fisheries Technology Conference
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    • 2003.05a
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    • pp.363-365
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    • 2003
  • 개조개(Saxidomu purpuratus)는 우리나라 전 연안에 분포하고 있으며, 연평균 생산량은 약 약 7,300들 정도가 어획되어지며, 경남 남해안 생산량이 전국 생산량의 약 73% 이상을 차지하고 있다. 본 종은 2001년부터 TAC 실시 대상 어종으로 선정되어 자원이 관리되어지는 실정에 있다. 따라서 개조개 자원을 보다 더 합리적으로 관리하기 위해서는 이 자원에 대한 자원생물학적 특성치인 자연사망계수, 어획사망계수, 생잔율, 어획개시연령 정확한 정보가 있어야만 효율적이고 종합적인 관리 발안을 수립할 수 있을 것이다. (중략)

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A Similarity-based Inference System for Identifying Insects in the Ubiquitous Environments (유비쿼터스 환경에서의 유사도 기반 곤충 종 추론검색시스템)

  • Jun, Eung-Sup;Chang, Yong-Sik;Kwon, Young-Dae;Kim, Yong-Nam
    • Journal of the Korea Society of Computer and Information
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    • v.16 no.3
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    • pp.175-187
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    • 2011
  • Since insects play important roles in existence of plants and other animals in the natural environment, they are considered as necessary biological resources from the perspectives of those biodiversity conservation and national utilization strategy. For the conservation and utilization of insect species, an observational learning environment is needed for non-experts such as citizens and students to take interest in insects in the natural ecosystem. The insect identification is a main factor for the observational learning. A current time-consuming search method by insect classification is inefficient because it needs much time for the non-experts who lack insect knowledge to identify insect species. To solve this problem, we proposed an smart phone-based insect identification inference system that helps the non-experts identify insect species from observational characteristics in the natural environment. This system is based on the similarity between the observational information by an observer and the biological insect characteristics. For this system, we classified the observational characteristics of insects into 27 elements according to order, family, and species, and proposed similarity indexes to search similar insects. In addition, we developed an insect identification inference prototype system to show this study's viability and performed comparison experimentation between our system and a general insect classification search method. As the results, we showed that our system is more effective in identifying insect species and it can be more efficient in search time.

Analysis of current density distribution and in vitro exposure system for ELF exposed cell experiments (ELF 전자파 피폭 세포실험을 위한 배양기의 전류밀도 분포해석 및 Invitro 노출장치 설계)

  • 김대근;정재승;안재목
    • Proceedings of the Korea Electromagnetic Engineering Society Conference
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    • 2000.11a
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    • pp.297-301
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    • 2000
  • ELF 전자파의 생물학적인 영향 평가를 위한 in vitro 세포 실험에서 노출장치의 설계는 코일내피 유도기전력(E)과 전류밀도(J) 해석과 함께 이루어져야 한다. 균일 자기장 속에서 세포를 배양할 경우애도 배양기내의 전도성 매질로 인해 균일한 E와 J가 분포하지 않는다. 따라서 균일한 ELF 자기장 노출장치로부터 발생되는 샘플 매질 내에서의 E나 J를 정확히 예측하는 것은 in vitro 세포실험의 성공여부를 가늠 할 정도로 매우 중요한 정보가 된다. 이에 본 논문에서는 in vitro 실험에 적합한 ELF in vitro 노출 장치를 설계하고 노출 장치에 대한 전자기학적 평가를 수행하였다. 코일 내에서 샘플 매질의 유무와 샘플 내에서도 세포가 놓여질 임의의 위치에 따라 E와 J를 예측하고 검증을 위한 측정과 시뮬레이션을 시도하였다. 노출장치는 헬름 홀쯔 코일로 제작되었고 자기장의 세기는 1-2OG 범위 내에서 가변이 가능하다. 또한 코일내의 자기장의 분포가 균일(uniform), 비균일(nonuniform)만 두 가지모드를 각각 제작하여 보았다.

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홀로그래픽 회절 토모그래피와 그 생물학적 응용

  • Gang, Pil-Seong;Choe, Won-Sik
    • Broadcasting and Media Magazine
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    • v.18 no.3
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    • pp.95-108
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    • 2013
  • 디지털 홀로그래픽 현미경이나 정량적 위상 현미경(quantitative phase microscopy)과 같은 기존의 간섭현미경은 3차원 이미징 기술로 분류되는데, 이는 획득한 이미지의 복소장(complex field)을 계산을 통해 다른 깊이로 전파시킬 수 있기 때문이다. 그러나 엄밀한 의미에서는 하나의 복소장 이미지는 단지 2차원 맵이기 때문에 근본적으로는 샘플의 2차원 정보만을 가지고, 물체의 3차원 구조의 일부분을 측정하는 것에 지나지 않는다. 본 논문에서는 1969년에 Wolf가 제안한[1,2] 홀로그래픽 회절 토모그래피(Optical Diffraction Tomography: ODT)를 실험적으로 구현한 3차원 위상 현미경(Tomographic Phase Microscopy: TPM)을 소개하고자 한다. TPM은 샘플을 다양한 각도로 조명하여 서로 다른 입사각에 대해 복소장 이미지를 얻고, ODT를 통해서 샘플의 3차원 구조를 복원해내는 기술이다. 보다 구체적으로는 다양하고 독립적인 2차원 이미지들을 샘플의 3차원 푸리에 공간에 맵핑함으로써 샘플 단면의 흡수율과 굴절률을 복원할 수 있다. 굴절률은 분자 농도와 비례하기 때문에, 살아있는 세포에 대한 굴절률의 3차원 맵을 얻을 수 있으면 세포 내부의 분자 구성을 연구할 수 있고, 이를 통해 다양한 생의학적 응용을 연구할 수 있다.

Current Concept of Biomimicry - Ecological Approach for Sustainable Development - (생태모방의 현재적 개념 - 지속가능한 발전을 위한 생태적 접근 -)

  • Bae, Haejin;Park, Eun Jin;Lee, Eunok
    • Korean Journal of Environment and Ecology
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    • v.33 no.1
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    • pp.116-123
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    • 2019
  • This study focused on defining concepts such as biology push (biology-based biomimicry) and technology pull (technology problem-based biomimicry) in the multidisciplinary field of ecological imitation and analyzing the status of related research and technology at the domestic and international levels. From an ecological point of view, biomimicry is defined as ecological mimicry in which ideas obtained through classification and investigation of principles of biology and ecology are applied to the concepts of engineering and technology. We also defined the biology push as the ecological imitation based on biological characteristics starting from an ecological viewpoint and technology pull as the ecological imitation based on technical problems starting from technical needs. Although biomimicry studies often focus on the technology development by finding stable and eco-friendly source materials from biological and ecological characteristics, we wanted to emphasize the unlimited potential of research of biomimicry that can begin with an idea based on biological and ecological characteristics. This study presents the need to develop the research and technology further based on the biological and ecological viewpoints that can contribute to future sustainable development.

Estimating Amino Acid Composition of Protein Sequences Using Position-Dependent Similarity Spectrum (위치 종속 유사도 스펙트럼을 이용한 단백질 서열의 아미노산 조성 추정)

  • Chi, Sang-Mun
    • Journal of KIISE:Software and Applications
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    • v.37 no.1
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    • pp.74-79
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    • 2010
  • The amino acid composition of a protein provides basic information for solving many problems in bioinformatics. We propose a new method that uses biologically relevant similarity between amino acids to determine the amino acid composition, where the BOLOSUM matrix is exploited to define a similarity measure between amino acids. Futhermore, to extract more information from a protein sequence than conventional methods for determining amino acid composition, we exploit the concepts of spectral analysis of signals such as radar and speech signals-the concepts of time-dependent analysis, time resolution, and frequency resolution. The proposed method was applied to predict subcellular localization of proteins, and showed significantly improved performance over previous methods for amino acid composition estimation.

Heterogeneous Clustering Ensemble Method using Evolutionary Approach with Different Cluster Results (다양한 클러스터 결과에 의해 진화적 접근법을 사용하는 이종 클러스터링 앙상블 기법)

  • Yoon Hye-Sung;Ahn Sun-Young;Lee Sang-Ho;Cho Sung-Bum;Kim Ju-Han
    • Proceedings of the Korean Information Science Society Conference
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    • 2006.06a
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    • pp.16-18
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    • 2006
  • 데이터마이닝 기법의 클러스터링 알고리즘은 생물정보학에서 데이터 셋의 사전 정보를 고려하지 않고 중요한 유전적, 생물학적 상호작용을 찾기 위하여 적용되고 있다. 그러나 다양한 형식의 수많은 알고리즘들은 바이오데이터의 다양한 특성들과 실험의 가정 때문에 다른 클러스터링 결과들을 만들 수 있다. 본 논문에서는 바이오 데이터 셋의 특성에도 적합하면서 양질의 클러스터링 결과를 만들기 위한 새로운 방법을 제안한다. 이 방법은 여러 가지 클러스터링 알고리즘의 결과들을 유전자 알고리즘의 기본 개념인 진화적 환경에서 가장 적합한 형질을 선택하는 문제와 결합하였다. 그리고 실제 데이터 셋을 이용하여 우리의 제안하는 방법을 증명하고 실험 결과로 최적의 클러스터 결과를 보인다.

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Comprehensive Analysis of Exposed Adverse Factors in Disaster Response Activities - Focused on Fire - (재난 대응 활동 시 노출가능 유해인자 종합분석 -화재 현장을 중심으로-)

  • Park, Chanseok
    • Journal of the Society of Disaster Information
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    • v.10 no.3
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    • pp.420-430
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    • 2014
  • Firefighters performing disaster response activities such as Fire Suppression Rescue First Aid in fire are being exposed in various adverse factors, heat, smoke, toxic gases, emotional stress, biological toxic factors and physical overload by unnatural ergonomic posture required for firefighters. But so far, there is the study for this problem only separately. There is no study about comprehesive analysis of exposed adverse factors in fire-related disaster response activities and countermeasures. The purpose of this study is to contiribute to solving the health problems and prevention of accidents of firefighters by extracting hazardous agents in disaster such as fire and by proposing countermeasures. After analyzing circumstances such as fire-suppression, rescue first aid and life-environment, exposure factors of fire are derived and exposure status is suggested according to physical chemical biological psychological aspects. The countermeasure against the noise of the physical exposure factors are proposed. The countermeasures such as protective equipment and clean room in chemical factors, infection prevention education, vaccination and periodic check system in biological factors, PTSD alleviation booth and mentoring in psychological factors are proposed.

A Node Scheduling Control Scheme with Time Delay Requirement in Wireless Sensor Actuator Networks (무선 센서 엑츄에이터 네트워크에서의 시간지연을 고려한 노드 스케줄링 제어 기법)

  • Byun, Heejung
    • Journal of Internet Computing and Services
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    • v.17 no.5
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    • pp.17-23
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    • 2016
  • Wireless sensor-actuator networks (WSANs) enhance the existing wireless sensor networks (WSNs) by equipping sensor nodes with an actuator. The actuators work with the sensor nodes and perform application-specific operations. The WSAN systems have several applications such as disaster relief, intelligent building, military surveillance, health monitoring, and infrastructure security. These applications require capability of reliable data transfer to act responsively and accurately. Biologically inspired modeling techniques have received considerable attention for achieving robustness, scalability, and adaptability, while retaining individual simplicity. In this paper, an epidemic-inspired algorithm for data dissemination with delay constraints while minimizing energy consumption in WSAN is proposed. The steady states and system stability are analyzed using control theory. Also, simulation results indicate that the proposed scheme provides desirable dissemination delay and energy saving.