• Proceedings of the Korean Geotechical Society Conference
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• 2004.03a
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• pp.176-187
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• 2004

서울ㆍ경기지역은 한반도의 서부중앙지역으로 동경 126$^{\circ}$와 127$^{\circ}$, 북위 36$^{\circ}$와 38$^{\circ}$ 사이에 위치해 있으며, 면적은 서울 605$\textrm{km}^2$, 경기도 10,184$\textrm{km}^2$를 차지한다. 북쪽으로는 휴전선, 서쪽으로는 서해, 동쪽으로는 강원도, 남쪽으로는 충청도와 접하고 있으며 한강에 의해 남북지역으로 나뉘어져 한 수 이북은 산간지역이 한 수 이남지역에는 평야지대가 발달하고 있다. 지형은 대체로 추가령 구조곡을 경계로 북부산지와 남부산지로 나누어지는데, 북부는 중국 요동방향의 마식령산맥, 남부는 중국방향의 광주산맥과 차령산맥이 각각 그 골간을 이루고 있으며, 서쪽해안에 가까워질수록 고도가 낮아져 평야나 구릉성 산지로 바뀐다.(중략)

• Journal of the Korea Organic Resources Recycling Association
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• v.17 no.4
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• pp.48-58
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• 2009

Glycosyl hydrolases (GH, EC 3.2.1.-) are key enzymes which can hydrolyze the glycosidic bonds between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. The new enzyme nomenclature of glycoside hydrolases is based on their amino acid sequence similarity and structural features. Here, we examined the glycosyl hydrolase family(GHF) genes reported from earthworm species. Among overall 115 GHFs, 12 GHFs could be identified from earthworm species through CAZy database. Of 12 GHF group genes, five genes including GHF2, 5, 17, 18, 20 are thought to be potent for industrial applications. The alignment of these genes with same genes from other animal species exhibited high sequence homology and some important amino acid residues necessary for enzyme activity appeared to be conserved. These genes can be utilized as a pest control agent or applicable to the food industry, clinical therapeutics and organic wastes disposition.

• Journal of the Korean Society for information Management
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• v.26 no.3
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• pp.7-24
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• 2009

Since the Web is dynamic, it is necessary to analyze scholarly Web space with both quantitative and qualitative methods for better understanding of communication characteristics. In this study, we analyzed contents of pages and links to ascertain the characteristics of Korean scholarly Web space in terms of network structure and communication behavior. The result shows that the structure of the original network with all the external links remained is not much different from that of the network with activated external links only. However, the purposes of linking vary among scholarly institutions. The centrality measures correlate more strongly with the clustering coefficient than with the constraint index implying the similar explanatory power of the two types of structural indices.

• Tuberculosis and Respiratory Diseases
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• v.66 no.4
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• pp.280-287
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• 2009

Background: The epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), became an attractive therapeutic option for advanced non-small-cell lung cancer (NSCLC). Several studies suggested that there might be some different efficacy or response predictors between gefitinib and erlotinib. We compared the efficacy and toxicity of gefitinib and erlotinib in Korean patients with advanced NSCLC and evaluated specific predictors of response for both gefitinib and erlotinib. Methods: We collected the clinical information on patients with advanced NSCLC, who were treated with gefitinib or erlotinib at the Ewha Womans University Hospital, between July 2003 and February 2009. Median survival times were calculated using the Kaplan-Meier method. Results: Eighty-six patients (52 gefitinib vs. 34 erlotinib) were enrolled. Patient median age was 64 years; 53 (62%) subjects were male. Out of the 86 patients treated, 83 received response evaluation. Of the 83 patients, 35 achieved a response and 12 experienced stable disease while 36 experienced progressive disease, resulting in a response rate of 42% and a disease control rate of 57%. After a median follow-up of 502 days, the median progression-free and overall survival time was 129 and 259 days, respectively. Comparing patients by treatment (gefitinib vs erlotinib), there were no significant differences in the overall response rate (44% vs. 39%, p=0.678), median survival time (301 days vs. 202 days, p=0.151), or time to progression (136 days vs. 92 days, p=0.672). Both EGFR-TKIs showed similar toxicity. In a multivariate analysis using Cox regression model, adenocarcinoma was an independent predictor of survival (p=0.006; hazard ratio [HR], 0.487; 95% confidence interval [CI], 0.292-0.811). Analyses of subgroups did not show any difference in response predictors between gefitinib and erlotinib. Conclusion: Comparing gefitinib to erlotinib, there were no differences in the response rate, overall survival, progression-free survival, or toxicity. No specific predictor of response to each EGFR-TKI was identified.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.16 no.3
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• pp.121-143
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• 2021

As the social economy emerges as one of the alternatives for solving social problems, interest and experiments on social franchise, a methodology for scaling the social economy, continue to increase. The success or failure of social franchise has a huge impact on franchisors, members of franchisees, as well as beneficiaries, local residents, and stakeholders in the region, but research on ways to increase their chances of success is still insufficient. Based on previous studies, this study tried to derive success factors by analyzing the effects of social franchise characteristics on business performance, and to understand the mediating effect of franchise autonomy, which is the differentiation point of social franchises, between characteristic factors and business performance. Social value orientation, social economy experience, local network utilization, and customer orientation were derived as characteristic factors affecting business performance, and franchise autonomy was set as a mediating variable, and a survey was conducted for franchisee members and their influence was analyzed. Through this study, it was found that social economy experience and local network utilization had a positive (+) effect on economic performance, and social value orientation, local network utilization, and customer orientation had a positive (+) effect on social performance. Also, the results of franchise autonomy playing a mediating role between social economy experience, local network utilization and economic performance, and a mediating role between local network utilization and social performance were presented. This study has significance as the first study to conduct a full-scale empirical study on social franchises. It is hoped that theoretical research on social franchises will be more active in the future and will be used as a useful reference for performance creation for organizations that seek or already operate social franchises.

• Korean Journal of Labor Studies
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• v.17 no.1
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• pp.325-350
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• 2011

This article examines part-time work in the UK in terms of its characteristics and institutional contexts. Part-time jobs developed early due to the UK's liberal market institution and low level of public support for female employment. A large proportion of the employed women (about 40 percent) work part-time. Part-time work has been largely for married women. The expansion of part-time work in the UK was primarily market-driven and led by employers. Married women have worked part-time work primarily to accommodate their family responsibilities. There have been significant changes in labor market regulation in the UK since 1997. The Labor government legislated the Part-time Workers Regluations in 2000 to protect part-time workers. The government has also changed and newly implemented various laws and policies for work-life balance. There has been a real progress in improving the quality of part-time work overall. Nevertheless, we have not seen qualitatively different results in terms of female employment patterns and the qualify of part-time work so far. It has been largely constrained by the government's liberal orienation and voluntarism of labor relations in the UK.

• Convergence Security Journal
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• v.19 no.2
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• pp.3-9
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• 2019

Most of security countermeasures have been implemented to cope with continuous increase leakage of technology, but almost security countermeasures are focused on securing the boundary between inside and outside. This is effective for detecting and responding to attacks from the outside, but it is vulnerable to internal security incidents. In order to prevent internal leakage effectively, this study identifies activities corresponding to technology leakage activities and designes technology leakage activity detection items. As a design method, we analyzed the existing technology leakage detection methods based on the previous research and analyzed the technology leakage cases from the viewpoint of technology leakage activities. Through the statistical analysis, the items of detection of the technology leakage outcomes were verified to be appropriate, valid and reliable. Based on the results of this study, it is expected that it will be a basis for designing the technology leaking scenarios based on future research and leaking experiences.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.211-211
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• 2013

나노 크기의 공간에서의 물질의 이동은 표면의 환경에 의해 영향을 받을 수 있다. 소수성그래핀과 친수성 실리콘 기판 사이의 계면에서의 물의 확산은 호기심을 자극할 뿐만 아니라 그래핀 소자의 특성을 좌우하는 전하도핑(charge doping) 현상을 이해하는데 중요한 모델이 된다. 본 연구에서는 라만 분광법과 원자 힘 현미경을 사용하여 그래핀/SiO2 계면 사이의 물의 확산 현상과 그에 따른 정공 밀도 변화를 탐구하였다. 열처리 된 그래핀은 기판과의 상호 작용에 의해 높은 밀도의 정공(electron hole)으로 도핑 되어 있으며, 이를 물에 담지 하였다. 본 실험에서는 이차원 라만 분광법을 통해 물 속에 담겨진 그래핀의 정공 밀도의 공간적인 분포를 확산 시간에 따라 조사하였다. 물의 확산은 시료에 따라 수 시간에서 수 일의 시간대에 걸쳐 그래핀 가장자리에서 중앙으로 이루어진다는 사실을 확인하였다. 또한 물의 계면 확산으로 인하여 전하 밀도가 감소한다는 사실은 열처리 된 그래핀의 정공 도핑을 유발하는 산소가 계면에 존재한다는 것을 증명한다.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.26 no.10A
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• pp.1645-1652
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• 2001

제3세대 이동 통신 시스템에서 상향 링크와 하향 링크 사이에 불균형적인 타임 슬롯 할당이 가능한 TD/CDMA TDD 시스템은 비대칭적인 트래픽을 효과적으로 분배하는데 적합하다. 게다가 TD/CDMA TDD 시스템은 슬롯이 시간 영역과 코드 영역에서 정의되기 때문에 유효 자원의 statistical multiplexing이 매우 효과적이다. 그러나 상향 링크와 하향 링크사이의 트래픽의 비대칭성을 반영하기 위해서 타임 슬롯을 최적으로 할당시킬 수 있는 동적 경계선이 요구된다. 본 논문에서 슬롯의 하향 링크부분이 이동국의 접근 시도의 정도에 따라 최대화되는 새로운 최적의 TDD 경계선 제어 움직임 알고리즘을 제안하였다. 제안된 알고리즘에서 이동국의 평균 접근 시도가 미리 정의된 상한 임계치를 초과할 경우, TDD 경계선은 평균 접근 시도가 다른 하한 임계치 아래로 내려갈 때까지 프레임의 중앙에 위치한다. 본 논문에서 모의실험 결과를 통하여 제안된 알고리즘이 기존의 TDD 경계선 알고리즘보다 데이터 트래픽의 평균 접근 지연과 음성 트래픽의 블록킹 확률 측면에서 훨씬 더 좋은 성능을 나타냄을 입증하였다.

• The Korean Journal of Zoology
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• v.38 no.1
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• pp.26-37
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• 1995

뱀장어, Anguilla joponicu의 표피를 구성하는 주종 세포인 상피세포는 80남 정도의 많은 당김세사를 함유하고 있어서 표피의 골격 유지에 중요한 역할을 하고 있다 회유행동 특성에 의해. 성숙된 뱀장어는 바다로 나가게 되고 표피는 급격한 환경변화를 서게 되는데 그 현상들을 살펴보면 먼저 상해반응으로 세포 내의 파립 형질내세망의 내강이 확장되는 현상과 다양한 크기의 공포의 증가로 인해 상피세포들 사이의 공간이 확장되며 일부 세포에서는 괴사 또는 변성되는 형태인 다층층판구조를 갖기도 한다. 이에 대한 능동적 대처로 부착반쪽으로 모이는 당김세사들이 일정한 방향성을 갖게 되며, 상피세포 사이의 연접부위에 부착반의 수가 증가되며 미토콘드리아. 형질내세망 등 세포소기 관이 발달되고, 분비과립의 증가 등 분비양상이 증가되고, 능동적인 염배출과 연관된 핵상부의 중앙축을 따라 미토콘드리아 및 과립 형질내세망이 풍부한 세포도 나타났다. 이와 같은 변화는 염분농도의 증가에 따른 환경적요인에 의해 일어나는 상피세포의 기능적 방어기작이라고 사료된다.