• Childhood Kidney Diseases
• /
• v.13 no.2
• /
• pp.130-137
• /
• 2009

Purpose : Stem cell transplantation (SCT) has gained worldwide acceptance as a treatment for hematologic disorders. This study was performed to evaluate the clinical characteristics and outcomes of the acute kidney injury after SCT in children. Methods : The records of 53 patients who were treated with SCT at the pediatric department of Yeungnam University Hospital between January, 1996 and April, 2009 were used as subjects. Their were divided into two groups ; 'Early renal insufficiency' (ERI, n=18) and 'Non-early renal insufficiency' (NERI, n=35). ERI had greater than 25% of drop in GFR after SCT. Results: Total 53 patients were analyzed. In cord blood SCT (n=11), ERI was 4 (36.4%) and NERI was 7 (63.6%). In bone marrow SCT (n=16), ERI was 8 (50.0%) and NERI was 8 (50.5%). In autologous peripheral blood SCT (n=26), ERI was 6 (23.1%) and NERI was 20 (76.9%). There is no difference in both groups according to kinds of SCT. GVHD was developed in 22 patients, and there is no difference in each group. Twenty two of 53 patients died. ERI was 12 (66.7%) and NERI was 10 (28.6%). Acute renal failure is most important cause of the deaths. Conclusion : Out of 53 pediatric patients who were treated with SCT, 18 patients had greater than 25% of drop in GFR. There is no difference in both groups according to kinds of SCT. GVHD was found in 22 patients and there is no relation between GVHD development and acute kideney injury.

• Environmental and Resource Economics Review
• /
• v.7 no.2
• /
• pp.1-30
• /
• 1998

본 논문은 심각한 환경오염에 직면한 중국의 환경오염 현황을 살펴보고 향후 2010년까지의 대기환경오염을 추정하였다. 세계 3위의 에너지 소비국인 중국은 석탄을 주 에너지원으로 사용하고 있으며 이에 따라 대기오염이 심각해지고 있다. 중국인의 호흡기 질환은 10대 사망원인 중 1위가 되고 있으며 전체 사망원인의 27%를 차지하고 있다. 치명적인 피해를 주는 중국의 공해물질이 주변국인 우리 나라 상공에까지 대량 유입됨으로써 심각한 문제를 야기하고 있다. 1997년의 기후변화협약에서 선진국에서는 자발적인 $CO_2$ 감축목표를 설정하였고 이의 수단으로 배출권 거래제나 공동이행, 순삭감 방식을 결정한 바 있다. 이에 따라 향후에 예상되는 동북아 국가간 환경협력에 대하여 기본 자료 및 정책수립에 기초 환경정보를 제공하고자 한다.

• 건강소식
• /
• v.26 no.1 s.278
• /
• pp.8-15
• /
• 2002

새해가 밝으면 가족과 친지들끼리 덕담을 주고받으며 서로의 건강과 만사형통을 기원한다. 그러나 단지 건강을 바라는 마음만으로는 질병 없이 건강하게 살려는 꿈이 이루어지지 않을 것이다. 끊임없이 자신의 건강상태를 체크해보고 개인에게 맞는 건강관리법을 택해 꾸준히 관리하는 것이 건강을 유지하는 유일한 방법일 것이다. 우리나라의 주요 사망원인을 보면 암이 가장 많고 이어 뇌혈관 질환, 심장질환, 운수사고, 간질환 순을 나타났다. 이들 주요 사망원인들은 식생활이나 스트레스 관리, 운동, 안전수칙준수 등으로 충분히 예방할 수 있는 생활습관에서 오는 원인들이다. ‘이달의 건강길라잡이’에서는 주요 만성질환 예방 및 국민건강증진을 위하여 새해를 맞아 건강과 질병의 개념에 대해 알아보고 건강과 질병은 연장선상에 있는 것이며 따라서 건강은 꾸준히 관리해야만 한다는 것의 의미를 알아본다. 또한 암 · 심장질환 등 주요 만성 질병 예방을 위한 건강 지침을 제안하며 가족의 건강생활실천을 도모하고자 한다.

• The Monthly Diabetes
• /
• s.216
• /
• pp.10-13
• /
• 2007

요즈음은 인터넷이나 대중매체를 통해 일반인들도 다양한 질병에 대한 많은 정보를 얻을 수 있다. 이에 속하는 것으로 당뇨병은 대표적 만성질환이며 누구나 한번쯤은 들어 본 적이 있는 질환일 것이다. 현대와 같이 고도로 의학이 발달한 상황에서도 만성질환은 완치되는 것이 아니고 평생 관리를 해야하는 질병이기 때문에 많은 환자들이 살아가는 동안 서서히 지치게 되고 관리를 소홀히 하게 됨으로써 당뇨병성 신경병증, 망막증, 신증, 대혈관병증(뇌졸중, 심혈관질환, 말초혈관질환) 등과 같은 합병증의 발생으로 일상생활에 지장을 받게 된다. 따라서 당뇨병환자는 일생 주기적으로 검사와 함께 자신에게 맞는 약을 복용하고 경우에 따라서는 인슐린 주사까지 맞음으로써 지속적인 혈당관리를 하여 합병증의 발생을 최소화 하는 것이 필요하다. 이상에 언급한 다양한 합병증 중 가장 중요한 사망원인은 심혈관질환으로 40세 이후에 발생한 당뇨병환자에서 전체 사망 원인의 50% 이상을 차지한다. 또한 대부분의 당뇨병성 만성합병증이 적극적인 혈당관리로 효과적인 예방이 가능한 반면 심혈관질환과 같은 대혈관합병증은 혈당조절이 잘 되고 있는 환자에서도 당뇨병 발생 기간과 무관하게 발생하고 또 여러 혈관에 걸쳐 다발적이고 광범위하게 발생하므로 원인이 되는 다른 위험요소들에 대한 관리가 함께 이루어져야 한다.

• Journal of Veterinary Clinics
• /
• v.29 no.5
• /
• pp.416-421
• /
• 2012

A 10-year-old 4-kg spayed female Chihuahua with severe congestive heart failure was referred for surgical treatment. Through several examinations, the dog was diagnosed as severe mitral regurgitation (MR) and moderate TR. Because of the poor prognosis associated with continuation of medical management, surgical repair of the mitral valve was considered as the treatment option for the dog. The mitral valve repair was performed undergoing cardio pulmonary bypass (CPB) circuit. However after mitral repair, the dog was died without recovery from anesthesia. Many risk factors associated with failure of cardiac surgery are included CPB management, hypothermia, organ dysfunction, hemorrhage, hypotension, electrolyte & acid base imbalance, and infection. Although the dog is died from the operation, it is an important to reveal the factors of failure in veterinary clinic. From the case report, causes of failure of mitral valve repair can be considered from the failure of oxygenation and gas exchange by hypothermia and serious hypotension with low heart rate by low cardiac output syndrome (LCOS). Through the several considerations from this case, it is known that coming cardiac surgery for mitral valve repair is required to be more careful for successful operation. Further it can be brought to increase success rate in further operation.

• Journal of Chest Surgery
• /
• v.29 no.1
• /
• pp.38-42
• /
• 1996

Intraabdominal complications after cardiac surgery are infrequent, but often fatal. From 1985 to 1993, a total of 1241 cardiovascular operations requiring cardiopulmonary by pass were performed at Pusan Paik Hospital. A total of 16 intraabdominal complications occurred, represe ting a 1.3% incidence. Complications included enterocolitis in six, hepatitis in three, gastric bleeding in two, erosive gastritis in one, cholecystitis in one, spleen rupture in one, epididymitis in one, inguinal hernia in one patient. The overall mortality rate was 12.5% (2 of 16). Three of the 16 patients underwent surgical intervention, and one died. We concluded that intraabdominal complications after cardiac surgery are associated with a high mortality rate, so when evidence of an acute abdominal symptom is observed or conservativi medical treatment fails to improve symptoms, prompt early surgical intervention should be performed.

• The Korean Journal of Applied Statistics
• /
• v.17 no.3
• /
• pp.431-443
• /
• 2004

For the purpose of disease mapping, we consider the four small area estimation techniques to estimate the mortality rate of small areas; direct, Empirical estimation with total moment estimator and local moment estimator, Estimation based on hierarchial generalized linear model. The estimators are compared by empirical study based on lung cancer mortality data from 2000 Annual Reports on the Cause of Death Statistics in Gyeongsang-Do and Jeonla-Do published by Korean National Statistical Office. Also he stability and efficiency of these estimators are investigated in terms of mean square deviation as well as variation of estimates.

• Neonatal Medicine
• /
• v.18 no.2
• /
• pp.221-227
• /
• 2011

Purpose: The objectives were to identify the characteristics of neonates with hydrops fetalis, and to identify the risk factors associated with mortality. Methods: A retrospective review of AMC (Asan Medical Center) dataset was performed from January 1990 to June 2009. The characteristics of 71 patients with hydrops fetalis were investigated and they were divided into two groups: the survived group and the expired group. Various perinatal and neonatal factors in two groups were compared to find out risk factors associated with mortality based on univariate analysis, followed by multiple regression analyses (SPSS version 18.0). Results: Of those 71 neonates (average gestational age: 33 weeks, birth weight: 2.6 kg), 38 survived, 33 died, resulting in overall mortality rate of 46.5%. The most common etiology was idiopathic followed by chylothorax, cardiac anomalies, twin-to-twin transfusion, meconium peritonitis, cardiac arrythmias, and congenital infections. Factors that were associated independently with mortality in logistic regression analyses were low 5-minutes Apgar score, hyaline membrane disease and delayed in achieving 50th percentile ideal body weight for appropriate gestational age by 10 days. Conclusion: In this study, 5-minutes Apgar score, hyaline membrane disease and delayed in achieving 50th percentile ideal body weight for appropriate gestational age by 10 days were significant risk factors associated with mortality in hydrops fetalis. Therefore, the risk of death among neonates with hydrops fetalis depends on the illness immediately after birth and severity of hydrops fetalis. Informations from this study may prove useful in prediction of prognosis to neonates with hydrops fetalis.

• 월간산업보건
• /
• s.204
• /
• pp.33-35
• /
• 2005

• 월간산업보건
• /
• s.183
• /
• pp.45-47
• /
• 2003