• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.2
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• pp.87-92
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• 2015

Mucopolysaccharidosis (MPS) is an inherited disease entity associated with lysosomal enzyme deficiencies. MPS type 2, also known as Hunter syndrome, has a characteristic morphology primarily involving x-l inked recessive defects and iduronate-2-sulfatase gene mutation. The purpose of this case report is to provide important clues to help pediatricians identify Hunter syndrome patients earlier (i.e., before the disease progresses). A 30-month-old boy showed developmental delay and decreased speech ability. Physical examinations revealed a flat nose and extensive Mongolian spots. Brain magnetic resonance images (MRIs) showed bilateral multiple patchy T2 hyperintense lesions in the periventricular and deep white matter, several cyst-like lesions in the body of the corpus callosum, and diffuse brain atrophy, which were in keeping with the diagnosis. Based on these findings, the patient was suspected of having MPS. In the laboratory findings, although the genetic analysis of IDS (Iduronate-2-sulfatase) did not show any pathogenic variant, the enzymatic activity of IDS was not detected. We could confirm the diagnosis of MPS, because other sulfatases, such as ${\alpha}$-L-iduronidase, were detected in the normal range. Early enzymatic replacement therapy is essential and has a relatively good prognosis. Therefore, early diagnosis should be made before organ damage becomes irreversible, and brain MRIs can provide additional diagnostic clues to help distinguish the disorder.

• Geophysics and Geophysical Exploration
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• v.11 no.2
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• pp.137-147
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• 2008

Fault rupture directivity of the Odaesan earthquake, which was inferred to be the main cause of the high PGAvalue (> 0.1 g) unusually observed at the near-source region, was analyzed by using the data from the nearby (R < 100 km) dense seismic stations. The Boatwright's method (2007) was adopted for this purpose in which the azimuth and takeoff angle of the unilateral rupture directivity function could be estimated based on the relative peak ground-motions of seismic stations resulting from the nature of the rupture directivity. In this study, the approximate values of the relative peak ground-motions was derived from the difference between the log residuals of the point-source spectral model (Boore, 2003) for the main and secondary events based on the Random Vibration Theory. In this derivation, the spectral difference for a frequency range between the source corner frequencies of main and secondary events was considered to reflect only the effect of the fault directivity. The inversion result of the model parameters for the fault directivity function showed that the fault-plane of NWW-SEE direction dipping steeply to the North with high rupture velocity near upward in SE direction is responsible for the observed high level of ground-motion at the near-source region.

• Proceedings of the KSR Conference
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• 2007.11a
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• pp.1379-1385
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• 2007

In domestic transitional zone design, there is regulation to prevent generation of irregular substructure behaviors that negatively influence in prevention of plasticity settlement on approach section and contact section as well as relieve overall track rigidity by reducing sectional foundation and track stiffness difference, but design guideline that considers dynamic behavior of transitional track in actual service line is very insignificant. Therefore in this study, characteristics of transitional track dynamic behaviors by substructure stiffness are researched and measured dynamic response of transitional track by substructure stiffness in order to prove correlation between substructure and track and calculate elasticity(stiffness) and track load of transitional track by using measurement and formula to provide basic information for developing design guideline considering dynamic behavior of service line transitional track.

• The Journal of Korean Orthopaedic Ultrasound Society
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• v.1 no.1
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• pp.1-5
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• 2008

Purpose: We studied the diagnostic value of dynamic US in the extensor tendon dislocation at the metacarpophalangeal joint. Materials and Methods: From January 2007 to October, we studied 6 cases that had been diagnosed and followed over 5 months (2-10) in average. US examination using a 10-MHz linear transducer were performed in three cases. The causes of dislocations were traumatic in 5 cases and congenital in one case. Results: In only 3 cases which could not be diagnosed clinically, we performed US. In dynamic US, all three cases showed the extensor tendon dislocation evidently. Operative findings were sagittal band rupture in 4 cases, capsular loosening in one case and sagittal band thinning in one case. Sagittal band repair was performed in 4 cases and capsular augmentation in one case. In case of congenital dislocation showing 4 digital extensor tendon dislocations in right hand, we operated only the second extensor by sagittal band repair with augmentation by looping. At last follow-up, no case showed recurrence or limitation of motion. Conclusion: In case of extensor tendon dislocation without apparent clinical finding, US with dynamic study has so great value that it can detect the dislocation in real time, which is superior to MRI.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.5
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• pp.608-615
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• 2017

The objective of this study was to evaluate the physicochemical, structural, and rheological properties of new domestic potato cultivars ('Goun', 'Sebong', and 'Jinsun') against the foreign potato cultivar 'Atlantic'. Based on the results obtained from scanning electron micrograph, X-ray, and Fourier transform infrared spectrum analyses, the structural properties of all potato flours were not considerably different. Rapid visco analyzer analyses showed that the setback viscosities of 'Goun', 'Sebong', and 'Jinsun' were significantly lower than that of 'Atlantic'. For steady shear rheological properties, potato flour dispersions showed shear-thinning behaviors (n=0.45~0.49) at $25^{\circ}C$. Apparent viscosity and consistency index of 'Atlantic' were similar to those of 'Sebong' and 'Jinsun'. For dynamic shear rheological properties, storage modulus (G′) and loss modulus increased, whereas complex viscosity (${\eta}^*$) was reduced with increasing frequency from 0.63 to 62.8 rad/s. G′ and ${\eta}^*$ values of 'Jinsun' were significantly higher than those of the other potato cultivars.

• Nuclear Engineering and Technology
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• v.20 no.2
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• pp.88-104
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• 1988

The FUel Rod Analysis(FURA) code is developed using two-dimensional finite element methods for axisymmetric and plane stress analysis of fuel rod. It predicts the thermal and mechanical behavior of fuel rod during normal and load follow operations. To evaluate the exact temperature distribution and the inner gas pressure, the radial deformation of pellet and clad, the fission gas release are considered over the full-length of fuel rod. The thermal element equation is derived using Galerkin's techniques. The displacement element equation is derived using the principle of virtual works. The mechanical analysis can accommodate various components of strain: elastic, plastic, creep and thermal strain as well as strain due to swelling, relocation and densification. The 4-node quadratic isoparametric elements are adopted, and the geometric model is confined to a half-pellet-height region with the assumption that pellet-pellet interaction is symmetrical. The pellet cracking and crack healing, pellet-cladding interaction are modelled. The Newton-Raphson iteration with an implicit algorithm is applied to perform the analysis of non-linear material behavior accurately and stably. The pellet and cladding model has been compared with both analytical solutions and experimental results. The observed and predicted results are in good agreement. The general behavior of fuel rod is calculated by axisymmetric system and the cladding behavior against radial crack is used by plane stress system. The sensitivity of strain aging of PWR fuel cladding tube due to load following is evaluated in terms of linear power, load cycle frequency and amplitude.

• Journal of the Korean Society for Nondestructive Testing
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• v.28 no.4
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• pp.339-345
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• 2008

The heat exchanger tube in nuclear power plants is mainly fabricated from nonferromagnetic material such as a copper, titanium, and inconel alloy, but the moisture separator & reheater tube in the turbine system is fabricated from ferromagnetic material such as a carbon steel or ferrite stainless steel which has a good mechanical properties in harsh environments of high pressure and temperature. Especially, the moisture separator & reheater tubes, which use steam as a heat transfer media, typically employ a tubing with integral fins to furnish higher heat transfer rates. The ferromagnetic tube typically shows superior properties in high pressure and temperature environments than a nonferromagnetic material, but can make a trouble during the normal operation of power plants because the ferrous tube has service-induced damage forms including a steam cutting, erosion, mechanical wear, stress corrosion cracking, etc. Therefore, nondestructive examination is periodically performed to evaluate the tube integrity. Now, the remote field testing(RFT) technique is one of the solution for examination of ferromagnetic tube because the conventional eddy current technique typically can not be applied to ferromagnetic tube such as a ferrite stainless steel due to the high electrical permeability of ferrous tube. In this study, we have designed RFT probes, calibration standards, artificial flaw specimen, and probe pusher-puller necessary for field application, and have successfully carry out RFT examination of the moisture separator & reheater tube of nuclear power plants.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.308-308
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• 2021

다목적댐의 홍수조절운영에 있어서 댐유입량은 직접 관측의 어려움과 오차로 인해 정확한 유량을 산정하는데 한계가 있다. 남강댐 유역의 경우 유역면적대비 과소한 저수용량으로 말미암아 급격한 홍수유입이 발생할 경우 유출률이 비정상적 수치를 보이는 경우가 종종 발생하고 있다. 본 연구에서는 물리기반의 격자형 유출모형을 댐 직상류 잔유역에 적용하여 유출률을 산정 후 남강댐 계측유입량의 타당성을 간접적으로 검증할 수 있는 방법론을 제시하고자 한다. 댐유역에서 잔유역은 직상류 수위표지점 하류의 유역을 일컬으며, 이들 수위표지점에서 홍수시의 배수영향은 최소화될 만큼 이격되어 있고, 댐체 혹은 취수탑에 부착된 수위표와는 달리 기계적 진동의 영향이 최소화되어 있다고 가정한다면, 수위계측지점의 유량을 경계조건으로 활용하여 작은 면적에 대한 정밀한 수문학적 유출모델링을 통하여 비교적 신뢰성있는 유출값을 추정할 수 있다는 장점이 있다. 남강댐 잔유역은 유역 내 산청, 신안, 창촌 수위관측소를 기준으로 상류의 유역을 제외한 부분으로 설정하였다. 본 연구에서는 210m 격자에 대하여 모든 입력자료를 가공하였으며, 입력자료 중 지형자료는 WAMIS에서 제공한 DEM, 토지피복도, 토양도를 활용하였다. 강우자료는 유역 내 위치한 25개 강우관측소의 시단위 강우자료를 활용하였고, 강우사상은 진주 기상관측소의 일우량 100mm 이상을 기준으로 총 8개의 강우사상을 선정하였다. 남강댐 유역의 유출률을 산정하기 위해 산청, 창촌, 신안 등 3개의 수위관측소의 관측유량을 경계조건으로 사용하였고, 모의된 수문곡선의 총유량과 첨두유량을 관측값과 비교하였다. 유출률을 산정하기 위한 기준시간은 강우시작부터 강우종료 후 48시간으로 설정하였다. 유출률은 강우사상별로 편차가 심한 특성을 보이고 있었으며, 전체적으로는 계측유량기준 106~39.1%의 유출률이 보정된 유량을 통해서는 85~33%의 유출률로서 계측유량이 전반적으로 과대추정 되는 경향이 있었음을 확인할 수 있었다. 이들 중 2010년 7월 강우사상은 관측 유입량 기준 95.6%의 유출률을 보여, 추정유량 58.5%대비 상당한 과대추정 경향을 보인 사례로 판단할 수 있었다. 수문학적 유입량 추정방법은 현장계측을 대체할 수 있는 기법으로는 무리가 있으나 현장계측의 신뢰도를 평가하기 위한 목적으로는 유용한 대안이 될 수 있을 것으로 기대된다.

• Tuberculosis and Respiratory Diseases
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• v.44 no.5
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• pp.1030-1039
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• 1997

Background : Impulse Oscillometry is a noninvasive and effort-independent test used to characterize the mechanical impedance of the respiratory system. The clinical potential of the IOS is rapid and demands only passive cooperation which makes it especially appealing for children, for epidemiologic surveys and for conditions in which quiet breathig instead of forced expiratory maneuvers are preferred. However, several studies have shown conflicting results that the role of IOS about detection of smoking induced small airway diseases or early airway obstruction Methods : Study was to evaluate the clinical ability of the IOS to detect about smoking induced early airway obstruction in persons with normal spirometry test. Respiratory asymptomatic study groups were formed that one is non-smoking group, another is smoking group. Results : The parameters of spirometry were not significantly differences between non-smoking group and smoking group. Among the parameters of IOS, total resistance(non-smoking group : smoking group=$2.22{\pm}1.20$ : $2.58{\pm}1.71$), peripheral resistance($1.25{\pm}0.62$ : $1.47{\pm}0.10$), bronchial compliance($0.44{\pm}0.12$ : $0.47{\pm}0.16$) were not statistically significant different (p<0.05), but central resistance and lung compliance were not statistically significant different (unit ; resistance=hPa/l/s, compliance=l/hPa). Resistance(Rrs) was not statistically significant different with changes of frequences(5, 10, 15, 20, 25, 30, 35Hz), but Reactance(Xrs) was statistically significant different with low frequences that X5(non-smoking group : smoking group=$-0.62{\pm}0.28$ : $-0.76{\pm}0.48$, p<0.001) and X10($-0.06{\pm}0.19$ : $-0.15{\pm}0.33$, p<0.013) (unit; hPall/s, $hPa{\cong}cmH_2O$). Conclusion : Impulse oocillometer(IOS) is clinically available method to detect about smoking induced early airway obstruction. And clinically potential parameters of IOS were considers that total resistance, peripheral resistance, bronchial resistance, and reactance of low frequency at 5Hz, 10Hz.

• The Journal of the Petrological Society of Korea
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• v.21 no.3
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• pp.309-333
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• 2012

Basalt having lots of feldspar phenocryst occurred at the northern and southern slope of the Mt. Halla, Jejudo. Among them, the Sioreum trachybasalt in southern slope consists of abundant phenocrysts of plagioclase in aphanitic groundmass. And the number of plagioclase grains are about 20 per $10cm^2$, and based on 667 grains the sizes are 13~0.7 mm (average 4.23 mm) in length and 8.6~0.5 mm (average 2.3 mm) in width. In according to modal analyses, Sioreum basaltic rock consists mainly of plagioclase (16~28%), olivine, clinopyroxene (1.5~6%) and opaque minerals (~0.1%) of magnetite and ilmenite as phenocryst and microphenocryst and groundmass (60~82%). The compositions of plagioclase, olivine and clinopyroxene are bytownite~andesine, chrysolite~hyalosiderite, augite respectively. Plagioclase phenocrysts show different type of zoning, namely, normal, reversal, patchy, oscillatory type. The An contents of zoned plagioclase mainly increase from core to rim. Those of oscillatory type from core to rim show variations of increase following decrease or decrease following increase, being more enriched in rim or almost same to core. Under the microscope, some plagioclase phenocrysts are especially melted in core part or marginal part, or found as only the remnant remain which resulted from reaction with melt. Some clinopyroxene are also corroded in margin part or found as irregular shape resulted from melting. The characteristics of petrography and compositional variation from core to rim of plagioclase and clinopyroxene, indicate that they are disequilibrium with melt and has been undergone geological environmental changes in magma batch during crystallization including magma mixing with replenishment of more mafic and high temperature melt.