• Title/Summary/Keyword: 비방사능

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A study of Brain Micro-PET Imaging and Bindingpotential with a Different Specific Activity of 18F-Fallypride in the Small Animal (소동물에서 18F-Fallypride의 비방사능에 따른 뇌의 PET이미지와 Binding Potential 차이에 대한 연구)

  • Cho, Kyu-Sang;Ahn, Sung-Min
    • The Journal of the Korea Contents Association
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    • v.15 no.9
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    • pp.418-424
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    • 2015
  • In this study, we proceed if there are any changes in binding ability of receptor-ligand in some degree of SA and in radioactive uptake from the corpus striatum based on small animal experiment in vivo based on the S.A values. By dividing 18F-Fallypride into 3 S.A values(high S.A : 43.29~74 GBq/umol, ordinary S.A : 20.72~29.23 GBq/umol, low S.A : 6.29~8.51 GBq/umol), we injected directly into the veins and performed 90 minutes of dynamic scan using Micro PET. After scanning, we compared and analyzed with Binding Potential (Binding Potential) from the bilateral striatum. high SA and low SA, ordinary SA and low SA showed significant differences. Also, in the image comparison using 18F-Fallypride show high radioactive uptake in the striatum at high SA and ordinary SA, but the radioactive uptake at low SA is lower than other two SA. Since 18F-Fallypride has affinity to dopamine D2/3 pharmacokinetic, the difference of Binding Potentials at decreased level of SA values was not that significant. However, further PET research of the corpus striatum using 18F-Fallypride is necessary because the differences in images and Binding Potentials at 6.5 times smaller SA values compared to high SA value showed were significant.

Multi-Radioactivity Measurement System Design for Indoor Environmental Monitoring (실내 환경 모니터링을 위한 다중 방사능계측 시스템 설계)

  • Sagong, Byung-Il;Kim, Nam-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2022.05a
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    • pp.459-461
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    • 2022
  • In this paper, we propose a measurement system for measuring radioactivity detected in an indoor environment. This is to measure and prevent radiation generated in various spaces such as general house, workplace, and research institutes. Multi-radioactivity sensors are used to measure multiple spaces simultaneously. The measured radioactivity data is transmitted to the PC in real time through ZigBee and monitored. Even with a small amount of radioactivity, it is considered that it must be installed in a place where radiation exposure is expected, such as a laboratory or workplace, for prevention from chronic radiation syndrome.

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A Study on the Measurement of Activity Concentrations of Pu and Am and Their Isotopic Ratios in the Radioactively Contaminated Soil (방사능으로 오염된 토양에 대한 Pu 및 Am 방사능 농도 및 동위원소비 측정에 대한 연구)

  • Lee, Myung Ho;Song, Byoung Chul;Park, Young Jai;Kim, Won Ho
    • Analytical Science and Technology
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    • v.17 no.6
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    • pp.514-519
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    • 2004
  • Soil samples collected from around the BOMARC Missile Site were measured for their activity concentrations and isotopic ratios of Pu and Am isotopes with particle sizes. The activity concentrations of Pu and Am in the BOMARC soil were remarkably higher than the fallout levels, and the activities decreased nearly exponentially with an increasing particle size of the soil due to a decreasing surface area. The activity ratios of Pu-238 / Pu-239, 240, Pu-241 / Pu-239, 240 and Am-241 / Pu-239, 240 observed in the BOMARC soil were much lower than those attributed to the nuclear reprocess plants and the Chernobyl fallout. Also, the atomic ratio of Pu-240 / Pu-239 in the BOMARC soil was remarkably lower than the fallout value influenced by the nuclear weapons testing and the Chernobyl accident. The atomic ratio of Pu-240 / Pu-239 was so close to the value of the weapons grade Pu released from the crash of a B52 plane in the Thule of the Greenland, such that the Pu isotopes detected in the BOMARC soil could have originated from the weapons grade plutonium.

퍼지멤버쉽 함수를 이용한 환경중 방사능 비상 사고의 모델링

  • 정효준;황원태;서경석;김은한;한문희
    • Proceedings of the Korean Environmental Sciences Society Conference
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    • 2003.05a
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    • pp.407-408
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    • 2003
  • 다중입력조건에 따른 단일 출력퍼지시스템인 인구밀도와 도로조건에 따른 소개속도의 모델링시스템에서는 인구밀도와 도로조건의 퍼지멤버쉽에 대한 소개속도의 상승작용을 확인할 수 있었다. 그러나 도로조건을 평가하는 방법을 포장과 비포장으로만 구분함으로 인해 발생하는 퍼지추론과정에서 비탄력성은 향후 도로조건에 대한 세밀한 조사를 통하여 퍼지멤버쉽함수의 형태를 재고해야 할 것으로 판단된다. 실제 원자력시설에서 발생할 수 있는 사고의 경우 방사능에 노출될 수 있는 일반대중은 방사능에 대한 깊은 지식을 가지지 못하는 경우가 대부분이다. 따라서 차폐효과 혹은 소개속도를 정량적으로 파악하기 힘든 경우가 많다. 따라서, 이러한 퍼지시스템은 방사선 비상대응 시스템을 개발하는 의사결정자나 비상시 방사능에 노출되는 사람들의 대응 방식을 모델링하는데 유용할 것으로 판단된다.

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Biokinetics of Carbohydrate and Lipid Metabolism in Normal Laying Hen -II. Incorporation of Activity in Plasma Lipid After Injection of Glucose-U-$C^{14}$- (정상산란계(正常産卵鷄)에 있어서 탄수화물(炭水化物)과 지질대사(脂質代謝)의 생동역학(生動力學) -제2보(第二報) 방사능(放射能)$(C^{14})$포도당 주사후(注射後) 혈장(血漿) 지질(脂質)로의 방사능(放射能)의 병합(倂合)-)

  • Chiang, Y.H.;Riis, P.M.
    • Applied Biological Chemistry
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    • v.21 no.1
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    • pp.63-67
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    • 1978
  • The incorporation of activity in plasma lipid was determined after injection of $u-C^{14}-glucose$ to normal laying hen. The extraction of total lipid from plasma was carried out by the method of Floch et al. with some modifications. The counting of carbon-14 activity was conducted by a Beckman Liquid Scintillation System, The concentration of plasma lipid was estimated as much as 3,070mg per 100ml of plasma taken at 5 minutes after injection of tracer amount of $u-C^{14}-glucose$. The specific activity per gram of plasma lipid carbon atom per injected dose per kg body weight increased gradually following the time after injection until 120 minutes, whereas the glucose activity decreased logarithmically. The partial incorporation quotient of activity in plasma lipid from that of glucose was 0.73% until 120 minutes after the injection.

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HANARO Fission Moly Target으로서의 LEU와 HEU의 특성 비교

  • 조동건;김명현
    • Proceedings of the Korean Nuclear Society Conference
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    • 1997.05a
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    • pp.108-113
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    • 1997
  • 하나로(HANARO)를 이용하여 핵분열 방법으로 진단용 방사선원인 $^{99m}$ Tc의 모핵종인 Mo-99를 생산할 경우, HEU 및 LEU UO2 표적이 사용될 수 있다. 표적연료로서 HEU(93w/o $^{235}$ U)가 LEU(19.75w/o $^{235}$ U)에 비해 생성수율(Ci/gU)이 높게 나타났으며 제품의 질(quality)을 좌우하는 비방사능(Ci$^{99}$Mo/gMo)은 같게 나타났다. HEU가 같은 Mo-99의 방사능량을 얻기 위해서는 우라늄 장전량이 적어지므로 폐기물측면과 용해측면에서 이득이나 농축도를 고려하면, 큰 이득이 발생하지 않으므로 하나로에 LEU를 사용하는 것도 타당하다 할 수 있다.

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생물 공학 의약품의 품질관리에 관한 연구(비방사능 물질 표지법을 이용한 숙주유래 DNA의 검출법 개발)

  • 용군호;민홍기;김창민;오호정;한강현;최규실
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1993.04a
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    • pp.59-59
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    • 1993
  • 비방사능물질인 Biotin을 DNA probe에 표지하여 nonisotopic hybridization 방법을 사용하여 감도를 높임으로써, 손쉽게 생물공학 의약품의 품질관리에 사용되도록 하였다. Bethesda Research Laboratories(BRL) 회사 제품인 biotinylated probes-avidin alkaline phosphatase를 이용한 chemiluminescene detection방법으로 행하여 λ phage DNA, yeast DNA, E.coil DNA의 한계 검출 농도를 알아내고, 생물 공학 제품에 적용하였다. Dot blot hybridization 방법으로 행하여 λ phage DNA는 0.1pg, Yeast DHA는 4.5pg, E. coli DNA는 8.9pg까지 검출되었고, 기존 생물공학 제품에서는 숙주 유래 DNA가 전혀 검출되지 않았다.

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Analysis of Radioactivity in Coal Fly Ash (비산석탄회의 방사능 농도 분석)

  • Shin, Hyun-Sang;Lee, Myung-Ho;Kim, Mi-Kyung;Park, Doo-Wun;Lee, Chang-Woo;Rhee, Dong-Seok
    • Journal of Radiation Protection and Research
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    • v.24 no.4
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    • pp.187-193
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    • 1999
  • The specific radioactivity concentrations in the coal fly ash obtained from heat producing stations in Korea were analyzed and its radiological hazard for reuse in construction purpose was evaluated. The concentrations of uranium isotopes in the real fly ash measured by TBP solvent extraction method and $\alpha$-spectrometer were found to be about 116.1 Bq $kg^{-1}$ for $^{238}U$, 5.01 Bq $kg^{-1}$ for $^{235}U$, and 121.2 Bq $kg^{-1}$ for $^{234}U$, respectively. The activity ratio of $^{234}U/^{238}U$, in the coal fly ash was in $1.04\;{\pm}\;0.03$, which is similar to that of uncontaminated Korean soil in natural conditions (1.14). The specific radioactivities of $^{226}Ra,\;^{232}Th,\;and\;^{40}K$ in the coal fly ash were also determined using $\gamma$-spectrometer with a HPGe detector The results showed that $^{226}Ra,\;^{232}Th,\;and\;^{40}K$ in the coal fly ash were in concentrations of $101.7{\sim}113.9$, $39.5{\sim}54.2\;and\;315.0{\sim}990.6$ Bq $kg^{-1}$, respectively. With the specific radioactivities obtained from $\gamma$-spectrometric measurements of the coal fly ash, its radiological hazard for reuse was evaluated. The result showed that the radioactivity of the coal fly ash was in permissible level.

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방사능 고정화에 있어서 PVA-PMAA 계의 화학적 특성적 특성

  • 원휘준;안병길;정종헌;최왕규;오원진
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05d
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    • pp.157-162
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    • 1996
  • Poly(vinyl alcohol)(PVA)-poly(methacrylic acid)(PMAA) 계의 방사능 고정화에 대한 일련의 실험을 수행하였다. 전위차 적정 데이터와 FT-IR spectra 를 해석하여 PVA-PMAA 계의 화학적 특성을 설명하였다. 인위적으로 오염시킨 모래에 대한 침출실험 결과, $^{241}$Am, $^{154,155}$ Eu, $^{144}$ Ce의 전이 계수가 $^{l34,137}$ Cs 에 비해 높은 것으로 나타났다. 실험에 사용된 고분자 용액중, PVA-PMAA 계는 전체 방사능의 85% 이상을 차지하는 Cs 의 고정화에 효과적이었다.

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